Loading...
  • CD20
  • CD19 and CD20 play an important role in the development, differentiation, and activation of B cells. (aacrjournals.org)
  • In this study we set out to determine whether cytotoxic CD8 + T-cell responses specific for peptides derived from CD19 and CD20 antigens occur in healthy individuals and patients with B-cell malignancies. (aacrjournals.org)
  • Antibody FMC7 (Flinder Medical Centre) appears to recognise a conformational variant of CD20 also known as the FMC7 antigen. (wikipedia.org)
  • embryonic antigen
  • Feizi T, Kapadia A, Knowles BB, Solter D and Evans MJ (1981) Stage specific embryonic antigen involves 1,3 fucosylated type 2 blood group chains. (springer.com)
  • Knowles BB, Rappaport J and Solter D (1982) Murine embryonic antigen SSEA-1 is expressed on human cells and structurally related human blood group antigen I is expressed on mouse embryos. (springer.com)
  • It is also called Lewis x and SSEA-1 (stage-specific embryonic antigen 1) and represents a marker for murine pluripotent stem cells, in which it plays an important role in adhesion and migration of the cells in the preimplantation embryo. (wikipedia.org)
  • cell
  • Kapadia A, Feizi T and Evans MJ (1981) Cahnges in the expression and polarization of blood group I and i antigens in post-implantation embryos and teratocarcinomas of mouse associated with cell differentiation. (springer.com)
  • Antigens expressed on the Cell Membrane of T-Lymphocytes during differentiation, activation, and normal and neoplastic transformation. (online-medical-dictionary.org)
  • When the cDNA was transfected into COS and NIH 3T3 cells, the antigen was found on the cell surface and could be released by treatment with phosphatidylinositol-specific phospholipase C. The 69-kDa precursor is processed to the 40-kDa form. (pnas.org)
  • The mechanism for NK T cell-dependent differentiation of Ag-specific Tr cells mediating systemic tolerance was studied by defining the cytokine profiles in heterogeneous and enriched NK T spleen cells. (jimmunol.org)
  • A cell surface antigen that is expressed only during a specific period of embryological differentiation. (thefreedictionary.com)
  • Although T cell lymphomas occur infrequently, they express early T cell differentiation antigens and are less often aneuploid than are B cell tumors. (thefreedictionary.com)
  • The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells. (wikipedia.org)
  • Although it is present in over 90% of T-cell lymphomas, it is generally less effective at demonstrating this condition than is CD3 antigen. (wikipedia.org)
  • His another important achievement is the induction of antigen-specific T cell tolerance, which has been a distant dream of immunologists for pinpoint-targeted control of the immune system. (wikipedia.org)
  • Through the development of an anti-ICAM1 antibody against the newly found epitope, he succeeded in inducing antigen-specific T cell tolerance via the development of tolerogenic semi-mature dendritic cells (J Exp Med. (wikipedia.org)
  • The protein has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. (wikipedia.org)
  • CD48 was the first B-cell-specific cellular differentiation antigen identified in transformed B lymphoblasts. (wikipedia.org)
  • CD48 and CD2 molecular coupling together with other interaction pairs of CD28 and CD80, TCR and peptide-MHC and LFA-1 and ICAM-1 contribute to the formation of an immunological synapse between a T cell and an antigen presenting cell. (wikipedia.org)
  • pathways
  • Our findings underscore the importance of antigen-dependent, direct cytotoxic immune responses in stroke and suggest modulation of CTLs and their effector pathways as a potential new strategy for stroke therapy. (sigmaaldrich.com)