aaaaxxxAntigens cd82. Medical search. FAQ
  • Metastasis
  • In relation to cancer, CD82 function is to inhibit tumor invasion and suppresses tumor metastasis. (
  • The metastasis-suppressive effect of CD82 can be observed in the animal studies of cancer metastasis by re-introducing CD82 expression in various metastatic cancer cell lines such as prostate cancer AT6.1, prostate cancer LNCaP, fibroblastoma HT1080, melanoma MDA-MB-435, breast cancer LCC6, liver cancer MHCC97-H, and lung cancer LLC lines. (
  • The observations of CD82-mediated suppression of cancer metastasis in animal models are supported by a variety of clinical studies on the human cancers from prostate, breast, ovary, colon, lung, stomach, liver, and other organs. (
  • CD63
  • The vesicles derived from mammalian cells contain a family of integral membrane proteins that cross four times the lipid bilayer and are called tetraspanins [ 11 ], including the surface markers of lymphocytes and antigen-presenting cells such as CD37, CD9, CD53, CD63, CD81, and CD82. (
  • protein
  • Depending on the character of the Cyclopamine communicating protein, tetraspanins possess been suggested as a factor in the control of mobile migration, adhesion, and signaling.13C16 CD82 has been shown to be an important member of the tetraspanin superfamily of glycoproteins and appears to function by modulating the amounts, trafficking, or activity of its interacting partners in the TEM. (
  • Glycosylation
  • CD82 undergoes two types of post-translational modifications: glycosylation at its large extracellular loop and palmitoylation at the cysteine residues in or near cytoplasmic domains. (
  • molecules
  • CD1 molecules, like MHC I and II, play an equally important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. (
  • immune
  • Several pathways involved in acute phase response, complement activation, immune/defense response, and antigen processing and presentation were remarkably affected at the early stage of WED immunization. (
  • therefore
  • Therefore, EVs are potential biomarkers and antigens for vaccination, with potential uses for early diagnostic, and therapeutic applications in several diseases. (
  • publications
  • This graph shows the total number of publications written about "Antigens, CD14" by people in Harvard Catalyst Profiles by year, and whether "Antigens, CD14" was a major or minor topic of these publication. (