• Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD53:FITC (SM1137F). (acris-antibodies.com)
  • While MHC class I is ubiquitously expressed by almost all cells, MHC class II is mostly expressed by antigen-presenting cells (APCs) such as monocytes, macrophages, and dendritic cells. (biomedcentral.com)
  • CD53 is expressed on almost all hematopoietic cells such as B cells, monocytes, macrophages, neutrophils, und T cells, but not on erythrocytes and platelets. (miltenyibiotec.com)
  • CD53 mediates oxidative burst in monocytes and has been shown to interact with a number of proteins including IL-4, CD20, CD2, CD9, IL-2, VLA-4, and CD4. (miltenyibiotec.com)
  • Beinert T, Munzing S, Possinger K, Krombach F. Increased expression of the tetraspanins CD53 and CD63 on apoptotic human neutrophils. (springer.com)
  • The vesicles derived from mammalian cells contain a family of integral membrane proteins that cross four times the lipid bilayer and are called tetraspanins [ 11 ], including the surface markers of lymphocytes and antigen-presenting cells such as CD37, CD9, CD53, CD63, CD81, and CD82. (hindawi.com)
  • Deneka M, Pelchen-Matthews A, Byland R, Ruiz-Mateos E, Marsh M. In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53. (springer.com)
  • The malignant cells will typically express B cell-associated antigens (CD19, CD23, and dim CD20), low-level surface immunoglobulin (Ig) (K or L), and the T cell-associated antigen, CD5. (renalandurologynews.com)
  • CD53 antigen is exclusivelly expressed on leucocytes (not present on platelets, red blood cells and non-hematopoietic cells). (acris-antibodies.com)
  • CD53 is expressed on all leukocytes including plasma cells, but not on platelets, erythrocytes, and non-hematopoietic tissues. (miltenyibiotec.com)
  • Identification of the CD85 antigen as ILT2, an inhibitory MHC class I receptor of the immunoglobulin superfamily. (springer.com)
  • Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity. (springer.com)
  • Malissen B. An evolutionary and structural perspective on T cell antigen receptor function. (springer.com)
  • The specific function of CD53 has not yet been defined, but CD53 has been shown to modulate cell adhesion, migration, cell proliferation, and survival. (springer.com)
  • These cells are involved in external antigen (Ag) processing and antigenic peptide presentation in the context of MHC class II to CD4+ T helper (T h ) cells. (biomedcentral.com)
  • CD3ζ possesses a small extracellular part, a TM region, and a long cytoplasmic part that contains three immunoreceptor tyrosine-based activation motifs (ITAMs), which correspond to the six tyrosines that get phosphorylated upon antigen binding to the extracellular part of TCRαβ. (springer.com)
  • Pattern of expression of tetraspanin antigen genes in Burkitt lymphoma cell lines. (springer.com)
  • Functional annotation analysis reveals that both hematopoietic cell populations are more competent in MHC class II-associated antigen presentation and in T cell activation than non-hematopoietic cells. (biomedcentral.com)
  • CD53: May be involved in growth regulation in hematopoietic cells. (mybiosource.com)
  • Our results highlight the potential of cells of hematopoietic origin in local antigen presentation, whatever their Ly6C expression. (biomedcentral.com)
  • Mouse CD53 (aa 107-181) derived in Human Cells. (creativebiomart.net)
  • Kamoun M, Kadin ME, Martin PJ, Nettleton J, Hansen JA A novel human T cell antigen preferentially expressed on mature T cells and shared by both well and poorly differentiated B cell leukemias and lymphomas. (springer.com)
  • In mesangial cells, CD53 ligation stimulates the induction of DNA synthesis via the MEK-ERK pathway. (springer.com)
  • TCR-associated zeta-Fc epsilon RI gamma heterodimers on CD4-CD8- NK1.1+ T cells selected by specific class I MHC antigen. (springer.com)
  • CD53 is a member of the tetraspanin family of hydrophobic membrane-spanning proteins. (springer.com)