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  • human
  • Taken together, the results expand the pathogen binding properties of CD5 and CD6 and provide novel evidence for their therapeutic potential in human cystic echinococcosis. (classicistranieri.com)
  • Herpes virus infections induce loss of CD5 expression in the expanded CD8+ human T cells. (nordicbiosite.com)
  • Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis. (duke.edu)
  • BACKGROUND: We investigated sera from elderly subjects with and without age-related macular degeneration (AMD) for presence of autoantibodies (AAbs) against human macular antigens and characterized their identity. (duke.edu)
  • Freedman AS, Freeman G, Whitman J, Segil J, Daley J, Levine H, Nadler LM: Expression and regulation of CD5 on in vitro activated human B cells. (exbio.cz)
  • Alberola-Ila J, Places L, Cantrell DA, Vives J, Lozano F: Intracellular events involved in CD5-induced human T cell activation and proliferation. (exbio.cz)
  • MALT
  • We report a 35-year-old woman with multicentric CD5-positive mucosa associated lymphoid tissue (MALT) lymphoma of conjunctival region. (ispub.com)
  • The occurrence of multicentric conjunctival CD5-positive MALT lymphoma in the younger age further support to the notation that CD5+ MALT-lymphomas arising in the ocular adnexa might be characterized by an unusual clinical course. (ispub.com)
  • In recent studies, several cases of conjunctival CD5-positive MALT lymphoma have been reported [ 3 5 6 ]. (ispub.com)
  • Fig . 2B ) With exception of CD5 expression, the morphological findings and growth pattern of the neoplastic cells, led us to diagnosis of a malignant small cell B-cell non-Hodgkin lymphoma and sub-typed as extranodal marginal zone B-cell lymphoma of MALT type. (ispub.com)
  • vitro
  • Further in vitro assays demonstrate that membrane-bound or soluble CD5 and CD6 forms differentially modulate the pro- and anti-inflammatory cytokine release induced following peritoneal cells exposure to E . granulosus s . l . tegumental components. (classicistranieri.com)
  • subpopulation
  • CD5 is the phenotypic marker of a B cell subpopulation involved in the production of autoreactive antibodies.Disease relevance: CD5 is a phenotypic marker for some B cell lymphoproliferative disorders (B-CLL, Hairy cell leukemia, etc. (nordicbiosite.com)
  • CD5 is the phenotypic marker of a B cell subpopulation involved in the production of autoreactive antibodies. (exbio.cz)
  • novel
  • Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration. (duke.edu)
  • signals
  • CD5 and CD6 are two highly homologous class I SRs mainly expressed on all T cells and the B1a cell subset, and involved in the fine tuning of activation and differentiation signals delivered by the antigen-specific receptors (TCR and BCR, respectively), to which they physically associate. (classicistranieri.com)
  • CD5 may serve as a dual receptor, giving either stimulatory or inhibitory signals depending both on the cell type and development stage. (nordicbiosite.com)
  • These data suggest that signals mediated through CD5 on the B cell surface may modify the B cell maturation pathway from naive to memory transition. (nii.ac.jp)
  • disease
  • Disease relevance: CD5 is a phenotypic marker for some B cell lymphoproliferative disorders (B-CLL, Hairy cell leukemia, etc. (exbio.cz)
  • Mouse
  • Importantly, prophylactic infusion of soluble CD5 or CD6 significantly ameliorated the infection outcome in the mouse model of secondary cystic echinococcosis. (classicistranieri.com)
  • presence
  • Additionally, CD5 and CD6 have been shown to interact with and sense the presence of conserved pathogen-associated structures from bacteria, fungi and/or viruses. (classicistranieri.com)
  • show
  • Binding studies show that both soluble and membrane-bound forms of CD5 and CD6 bind to intact viable protoscoleces from E . granulosus s . l . through recognition of metaperiodate-resistant tegumental components. (classicistranieri.com)