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  • human
  • CD34 may also stimulate proportions of adult human HSCs to differentiate into full-fledged neurons. (neuromics.com)
  • CD34 staining of human tonsil tissue. (neuromics.com)
  • Here we show that the human placenta contains large numbers of CD34-expressing hematopoietic cells, with the potential to provide a cellular yield several-fold greater than that of a typical UCB harvest. (nih.gov)
  • The purpose of this study was to determine cryopreservation techniques for fetal human liver (FHL) CD34(+) cells. (biomedsearch.com)
  • Flow Cytometric analysis of normal Human peripheral blood cells labeling CD34 with Anti-Human CD45 FITC and either ab155377 (right histogram) at 0.25 µg/test in 100 µl final volume or an equal amount of Mouse IgG1 kappa Isotype Control APC (left histogram). (abcam.com)
  • Native purified CD34 from permanent human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia. (abnova.com)
  • Reversibility of CD34 expression on human hematopoietic stem cells that retain the capacity for secondary reconstitution. (abnova.com)
  • citation needed] Human HSCs express the CD34 marker. (wikipedia.org)
  • Human leukocyte antigen (HLA)-DR is positive in most patients. (wikipedia.org)
  • Before the cord blood is stored for later use, it undergoes viral testing, including tests for HIV and Hepatitis B and C, and tissue typing to determine Human Leukocyte Antigen type. (wikipedia.org)
  • cells
  • A concurrent patient group meeting eligibility but not receiving CD34+ cells will be evaluated similar to the treated group to assess the rate of significant spontaneous improvement in cardiac function without CD34+cell infusion. (bioportfolio.com)
  • C) CD34(+) cells are frozen at a concentration of 1 x 10(6)/ml, and D) a thawing temperature of 37 degrees C is used. (biomedsearch.com)
  • The presence of CD34 on non-hematopoietic cells in various tissues has been linked to progenitor and adult stem cell phenotypes. (wikipedia.org)
  • citation needed] CD34 is expressed in roughly 20% of murine hematopoietic stem cells, and can be stimulated and reversed. (wikipedia.org)
  • The Fc region of immunoglobulin E (IgE) becomes bound to mast cells and basophils and when IgE's paratopes bind to an antigen, it causes the cells to release histamine and other inflammatory mediators. (wikipedia.org)
  • The Duffy antigen is located on the surface of red blood cells, and is named after the patient in which it was discovered. (wikipedia.org)
  • It has been shown that these pre-endothelial/pre-hematopoietic cells in the embryo arise out of a phenotype CD34 population. (wikipedia.org)
  • The hypothesis of a bipotential precursor was further supported by the fact that endothelial cells and hematopoietic cells share many of the same markers, including Flk1, Vegf, CD34, Scl, Gata2, Runx1, and Pecam-1. (wikipedia.org)
  • CD34, found on endothelial cells. (wikipedia.org)
  • T cells become activated by recognising foreign antigens bound to antigen presenting cells (APC), in particular, dendritic cells. (wikipedia.org)
  • In order for naïve T cells to bind to their specific antigen, they need to experience physical contact with those cells. (wikipedia.org)
  • Therefore, T cells need a region where they can go to sample foreign antigens that have entered the body. (wikipedia.org)
  • The rolling mechanism helps the L-selectin molecules on the surface of naive T cells to weakly interact with GlyCAM-1 and CD34 molecules on HEV cells. (wikipedia.org)
  • molecules
  • The allergen binds to the antigen-binding sites, which are situated on the variable regions of the IgE molecules bound to the mast cell surface. (wikipedia.org)
  • chemokine
  • Finally, recent data suggest CD34 may also play a more selective role in chemokine-dependent migration of eosinophils and dendritic cell precursors. (wikipedia.org)
  • encounter
  • When they encounter such an antigen, the cell becomes activated, resulting in the immune system mounting a response against the causative agent of the infection. (wikipedia.org)
  • ELISA
  • MA5-17829 targets CD34/gp105-120 in ELISA, FACS, IHC (F), IHC (P), IP, and WB applications and shows reactivity with Mouse samples. (thermofisher.com)
  • Negative
  • A negative CD34 may exclude Ewing's sarcoma/PNET, myofibrosarcoma of the breast, and inflammatory myofibroblastic tumors of the stomach. (wikipedia.org)
  • Functions
  • Effector memory T-lymphocytes do not express L-selectin, as they circulate in the periphery and have immediate effector functions upon encountering antigen. (wikipedia.org)
  • express
  • Central memory T-lymphocytes, which have encountered antigen, express L-selectin to localize in secondary lymphoid organs. (wikipedia.org)
  • Blood
  • It carries the antigenic determinants of the Duffy blood group system which consist of four codominant alleles-FY*A and FY*B-coding for the Fy-a and Fy-b antigens respectively, FY*X and FY*Fy, five phenotypes (Fy-a, Fy-b, Fy-o, Fy-x and Fy-y) and five antigens. (wikipedia.org)
  • Since antigen levels are usually low, contact in blood circulation would be unlikely. (wikipedia.org)
  • Structure
  • Three-dimensional structure prediction of the interaction of CD34 with the SH3 domain of Crk-L. (abnova.com)
  • Molecular
  • Conversely, under other circumstances CD34 has been shown to act as molecular "Teflon" and block mast cell, eosinophil and dendritic cell precursor adhesion, and to facilitate opening of vascular lumina. (wikipedia.org)
  • lymphocyte
  • 2010 Application of HLA-A*0201/WT1 pentamer combined with intracellular IFNgamma+ staining in detecting circulating WT1 specific T cells in leukemia 2010 "Comparison of Wilms' tumor antigen 1-specific T lymphocyte generation soon after nonmyeloablative allergenic stem-cell transplantation in acute and chronic leukemia patients", published in Int J Hematol. (wikipedia.org)
  • markers
  • BPDCN are characterized by co-expression of CD4 and CD56 antigens in the absence of any specific myeloid or lymphoid lineage or markers, primary skin infiltrations followed by bone marrow involvement, and aggressive clinical course. (czytelniamedyczna.pl)
  • A category of rare and aggressive haematologic tumors co-expressing CD4 and CD56 antigens in the absence of any specific myeloid, B-, T-lymphoid or natural killer (NK) lineage markers is classified as blastic plasmacytoid dendritic cell neoplasms (BPDCN) according to the most recent 2008 WHO classification of tumours of haematopoietic and lymphoid tissues (1). (czytelniamedyczna.pl)
  • tissue
  • If preservation of these antigen epitopes is required for downstream applications, it is more suitable to use in this case the Neural Tissue Dissociation Kit (T) (# 130-093-231). (miltenyibiotec.com)
  • negative
  • A negative CD34 may exclude Ewing's sarcoma/PNET, myofibrosarcoma of the breast, and inflammatory myofibroblastic tumors of the stomach. (wikipedia.org)
  • Still during the double negative stage, CD34 expression stops and CD1 is expressed. (wikipedia.org)
  • role
  • Finally, recent data suggest CD34 may also play a more selective role in chemokine-dependent migration of eosinophils and dendritic cell precursors. (wikipedia.org)