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  • CD14
  • Antigens, CD14" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
  • This graph shows the total number of publications written about "Antigens, CD14" by people in Harvard Catalyst Profiles by year, and whether "Antigens, CD14" was a major or minor topic of these publication. (harvard.edu)
  • Below are the most recent publications written about "Antigens, CD14" by people in Profiles. (harvard.edu)
  • mast cells
  • Ex vivo, FcεRI stimulation of bone marrow-derived mast cells from CD151 −/− mice resulted in significantly enhanced expression of proinflammatory cytokines IL-4, IL-13, and TNF-α compared with wild-type controls. (jimmunol.org)
  • Collectively, our data indicate that CD151 exerts negative regulation over IgE-induced late phase responses and cytokine production in mast cells. (jimmunol.org)
  • Gene
  • However, unlike the RBC Blood Groups Systems, the HPA Systems were not named on a per gene or related gene basis with one or more antigens in each system. (bloodantigens.com)
  • Rather, one HPA gene can contain multiple HPA systems so in reality each biallelic antithetical antigen pair is really its own system. (bloodantigens.com)
  • For example, the HPA-1 system contains the antithetical antigens HPA-1a and HPA-1b, but this same gene also contains the HPA-4 system (HPA-4a and HPA-4b). (bloodantigens.com)
  • molecular
  • At the molecular signaling level, CD151 selectively regulated IgE-induced activation of ERK1/2 and PI3K, associated with cytokine production, but had no effect on the phospholipase Cγ1 signaling, associated with degranulation. (jimmunol.org)
  • immune
  • Several pathways involved in acute phase response, complement activation, immune/defense response, and antigen processing and presentation were remarkably affected at the early stage of WED immunization. (biomedcentral.com)
  • significantly
  • Only 3 mutations have been identified in humans to date, two (G533A and C511T), are predicted not to significantly alter CD151 function and are not associated with disease (Karamatic Crew et al. (atlasgeneticsoncology.org)
  • In this study, we show that CD151 deficiency significantly exacerbates the IgE-mediated late phase inflammation in a murine model of passive cutaneous anaphylaxis. (jimmunol.org)