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  • Itgax
  • Proteína ITGAX ou CD11c. (wikipedia.org)
  • O CD11c ( cluster de diferenciación 11c) ou cadea alfa X de integrina é unha subunidade de proteína transmembrana de tipo I que se expresa en altos niveis na maioría das células dendríticas humanas, e tamén en monocitos , macrófagos , neutrófilos , e algunhas células B que está codificada no xene ITGAX do cromosoma 16 humano . (wikipedia.org)
  • 1998). "Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb. (wikipedia.org)
  • murine
  • Atg16l1 deficiency in CD11c+DCs exacerbated DSS-induced murine colitis. (naver.com)
  • The CD11c MicroBeads UltraPure allow for the rapid and simple isolation of all defined murine DC subsets. (miltenyibiotec.com)
  • phenotype
  • The CD11c + CD8 + T cell moiety was characterized by its high killing activity and IFN-γ-producing ability, which represent an active phenotype of the effector CTLs. (biomedcentral.com)
  • functional studies
  • To date, the low frequency of these DCs in human blood has essentially prevented functional studies defining their specific contribution to antigen presentation. (rupress.org)