All variants bound the PfRH5 receptor basigin and were recognized by a panel of monoclonal antibodies. (nature.com)
Protein5
The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) has recently emerged as a leading candidate antigen against the blood-stage human malaria parasite. (nature.com)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike S1 Receptor-Binding Domain (RBD) Protein is a recombinant. (proteomecommons.org)
The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. (proteomecommons.org)
The spike protein on the surface of the SARS-CoV-2 virus binds to human cells and allows the virus to enter. (sciencefeedback.co)
The SARS-CoV-2 spike protein binds and modulates estrogen receptors. (medicatrix.be)
CD473
Antigens, CD47" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
This graph shows the total number of publications written about "Antigens, CD47" by people in this website by year, and whether "Antigens, CD47" was a major or minor topic of these publications. (rush.edu)
Below are the most recent publications written about "Antigens, CD47" by people in Profiles. (rush.edu)
CD381
1 2 Cell surface antigens CD38 and CD138 can be used to distinguish normal cells from clonal plasma cells, but more extensive use of immunophenotyping has been limited by a lack of universally accepted markers of MM. 3-5 Once diagnosed, the current standard-of-care for MM includes immunomodulatory drugs, proteasome inhibitors, steroids, and antibody therapies. (bmj.com)
Tumor2
Our main goal is to identify new tumor antigens specifically expressed at the tumor cell surface and to validate their potential use as new therapeutic targets through the development of antibody-based immune-therapies. (hipi-lab-saint-louis.fr)
Because 10% of Sézary patients display malignant T cells that do not express KIR3DL2, we pursue our search for specific tumor antigens. (hipi-lab-saint-louis.fr)
Platelet2
P-selectin glycoprotein ligand-1 ( PSGL-1 ) is a glycoprotein found on white blood cells and endothelial cells that binds to P-selectin (P stands for platelet ), which is one of a family of selectins that includes E-selectin (endothelial) and L-selectin (leukocyte). (wikidoc.org)
SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19. (medicatrix.be)
Pathways1
The development of an effective vaccine against the merozoite has proved exceptionally challenging, hindered by substantial levels of polymorphism in the most widely studied candidate antigens 4 and redundant erythrocyte invasion pathways 5 . (nature.com)
Cell1
Although malignant cells were identified as a clonal expansion of CD4+ T cell with memory phenotype, their phenotypic detection relies on the loss of pan-T cell antigens such as CD26 or/and CD7. (hipi-lab-saint-louis.fr)
Human cells1
This two-part narrative review presents evidence for the widespread harms of novel product COVID-19 mRNA and adenovectorDNA vaccines and is novel in attempting to provide a thorough overview of harms arising from the new technology in vaccines that relied on human cells producing a foreign antigen that has evidence of pathogenicity. (gospanews.net)
Basigin4
All variants bound the PfRH5 receptor basigin and were recognized by a panel of monoclonal antibodies. (nature.com)
CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). (creativebiomart.net)
Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.The primary amine of Biotinylated rh CD147 /EMMPRINwas chemically labeled by specially optimized long spacer biotin reagent without decreasing its bioactivity, and has been used successfully for easy detection in ELISA, dot blot or Western blot, immunohistochemistry applications using streptavidin or avidin-conjugated probes. (creativebiomart.net)
Recombinant human basigin (BSG, CD147) produced in HEK293 cells and purified from culture supernatant. (thenativeantigencompany.com)
Receptor4
[ 204 ] To minimize cytokine-release syndrome, a humanized anti-CD3 antibody (that does not bind human Fc receptor), visilizumab (HuM291), was evaluated in Phase I and II studies. (medscape.com)
T cell-targeted immunomodulators such as monoclonal antibodies against PD-1 or CTLA-4 are used in combination with T cells engineered with chimeric antigen receptor (CAR) (CAR-T cells) against several malignancies in clinical trials. (bdbiosciences.com)
An introduction to chimeric antigen receptor (CAR) T-cell immunotherapy for human cancer. (bdbiosciences.com)
Recombinant human angiotensin-converting enzyme 2 (ACE2) extracellular domain (18-615) was expressed in HEK293 cells using a C-terminal sheep Fc-tag and purified to SARS-CoV-2 receptor binding domain (RBD) of the spike protein binds to the host cell ACE2 receptor to facilitate viral entry into the cell. (thenativeantigencompany.com)
Protein3
The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) has recently emerged as a leading candidate antigen against the blood-stage human malaria parasite. (nature.com)
The binding of biotin with streptavidin or avidin is extremely strong, which is used widely in protein biochemistry. (betalifesci.com)
ACCURUN® SARS-CoV-2 Antigen Reference Material Kit is formulated for use with test methods that detect the nucleocapsid protein of SARS-CoV-2 virus. (thenativeantigencompany.com)
CD433
Antigens, CD43" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
This graph shows the total number of publications written about "Antigens, CD43" by people in UAMS Profiles by year, and whether "Antigens, CD43" was a major or minor topic of these publications. (uams.edu)
Below are the most recent publications written about "Antigens, CD43" by people in Profiles over the past ten years. (uams.edu)
Ligand1
Tumor cells can express the PD-1 ligand (PD-L1) on their surface to bind with PD-1 and activate this brake or off-switch of the immune system. (bdbiosciences.com)
Surface1
E. histolytica has unique isoenzymes, surface antigens, DNA markers, and virulence properties that distinguish it from other genetically related and morphologically identical species, such as E. dispar and E. moshkovskii . (basicmedicalkey.com)
Sensitivity1
Early reports dubbed increases in B cell antigen sensitivity a "neuraminidase effect," ( Cowing and Chapdelaine, 1983 ) and recent evidence has ascribed this phenomenon to sialic acid acting as a negative regulator of immune cell interactions ( Bagriacik and Miller, 1999 ). (frontiersin.org)
Targets1
Progress in this arena, however, is being made with a new generation of merozoite antigen targets identified in recent years that exhibit relatively low levels of polymorphism and against which functional neutralizing antibodies can be raised by vaccination. (nature.com)
In phase 2 (Donor-T-cell activation, differentiation, and migration), the infused donor T lymphocytes are responsible for triggering GVHD and proliferate after activation by the recipient antigens expressed on host cells. (medscape.com)
Our results suggest that extended AP-1 binding sites, together with adjacent binding sites for additional TFs, encode part of the information that governs transcription factor binding sites activity in the genome. (cusabio.com)