NystatinSpeciesBiocontrolHygroscopicusBiosynthesisNodosusAntibioticsAntibacterial and antifungalStrainsBiosynthetic gene clusterGenusMetabolitesEchinocandinsIsolatesStrainCandidaBacteriaRimosusTriazoleMarine-DerivedAntiparasiticActivityEnzymesSystemicPhytopathogenic fungiRDNAFluconazoleActinomycetesAgentsFermentationYeastCompoundAgentGeneticallyEvaluationActivitiesEffect
Nystatin4
- Nystatin is a polyene antifungal antibiotic obtained from Streptomyces nursei. (nih.gov)
- Nystatin (ointment) is an antifungal, polyene antibiotic that is FDA approved for the treatment of cutaneous or mucocutaneous mycotic infections caused by Candida [Monilia]albicans and other Candida species. (wikidoc.org)
- Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin. (biosergen.net)
- Nystatin cream or Nystatin ointment is an antifungal (yeast) medication that is derived from Streptomyces Noursei. (toothnature.com)
Species9
- Streptomyces netropsis is a bacterium species from the genus of Streptomyces. (wikipedia.org)
- List of Streptomyces species LPSN bacterio.net Straininfo of Streptomyces netropsis UniProt Deutsche Sammlung von Mikroorganismen und Zellkulturen [1] Blake, R.D. (2004). (wikipedia.org)
- Seven Streptomyces species ( Streptomyces rimosus, S. albus, S. riseoflavus, S. fumosus, S. spiralis, S. aureofaciens and S. flavogriseus) isolated from three different grassland soils were screened based on the morphology and their ability to produce chitinase. (springeropen.com)
- Culture filtrate of Streptomyces albus was able to inhibit the growth of all the selected pathogenic fungi namely Magnaporthe oryzae , Fusarium graminearum , Rhizoctonia solani , Puccinia species and Botyrtis cinerea whereas Streptomyces rimosus has the least inhibitory activity. (springeropen.com)
- Amphotericin B is a polyene antifungal isolated from Streptomyces species. (goldbio.com)
- Molecular characterization based on 16S rRNA gene sequencing of RP1A-12 identified it as a species of Streptomyces, closely related to S. flocculus. (icrisat.org)
- The results of this study showed that it may be possible to manage chickpea Fusarium wilt disease effectively by using Streptomyces species, as biocontrol agents. (plantprotection.pl)
- Demanding sustainable agriculture is increasingly highlighted as a biocontrol approach, particularly Streptomyces species known to produce a variety of antibiotic compounds and secondary metabolites. (online-rpd.org)
- In this study, we investigated the use of Streptomyces species formulations to enhance bacterial growth with nitrogen sources. (online-rpd.org)
Biocontrol1
- Culture filtrates and crude extracts of the potential candidates were screened further for extracellular antifungal activity and characterized for biocontrol and plant-growth-promoting traits. (icrisat.org)
Hygroscopicus1
- Rapamycin was used as a kind of original antifungal antibiotic, which is produced by Streptomyces hygroscopicus. (diagrade.com)
Biosynthesis3
- It is a triazole antifungal agent that inhibits fungal CYP450-mediated 14 alpha-lanosterol demethylation, which is essential in fungal ergosterol biosynthesis. (medscape.com)
- is involved in the biosynthesis of the antifungal agent validamycin A. (enzyme-database.org)
- To date, the different types of regulators involved in polyene macrolide biosynthesis have been categorized as follows: (1) Streptomyces antibiotic regulatory protein (SARP) family regulator, such as ActII-orf4, which regulates actinorhodin biosynthesis, and CcaR, which regulates clavulanic biosynthesis. (biomedcentral.com)
Nodosus2
- It is polyene antibiotic obtained from Streptomyces nodosus . (pharmacy180.com)
- Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela. (lookformedical.com)
Antibiotics3
- Streptomyces netropsis produces the antibiotics netropsin and distamycin A and the antifungal polyene mycoheptin. (wikipedia.org)
- Antifungal Agents - Antibiotics : 1. (pharmacy180.com)
- The ability of fungi to resist or to become tolerant to chemotherapeutic agents, antifungal agents, or antibiotics. (lookformedical.com)
Antibacterial and antifungal2
- Tunicamycin is an antibacterial and antifungal. (sigmaaldrich.com)
- A group of small, histidine-rich, cationic peptides in human SALIVA which are antibacterial and antifungal. (lookformedical.com)
Strains6
- However, there is some incidence for antifungal resistance among some Candida strains, limiting treatment options. (intechopen.com)
- The selected strains were identified as Streptomyces spp. (plantprotection.pl)
- Our results assigned them to strains related to genus of Streptomyces. (plantprotection.pl)
- In vitro, antagonistic effects of Streptomyces strains against the disease were evaluated through the dual-culture method, volatile and non-volatile metabolites, siderophore, protease and chitinase production. (plantprotection.pl)
- In addition, the biomass of chickpea plants (plant height and dry weight) significantly increased in plants treated with Streptomyces strains compared to non-bacterized control. (plantprotection.pl)
- Specifically, the addition of L-glutamic acid and L-cysteine resulted in earlier sporulation and bacterial growth in Streptomyces strains, respectively. (online-rpd.org)
Biosynthetic gene cluster1
- characterized the biosynthetic gene cluster of the tirandamycins in Streptomyces sp. (wikimili.com)
Genus2
- Sequencing showed that 93.3% were of the genus Streptomyces while 6.7% were of the genus Rhodococcus. (scirp.org)
- Streptomyces is a large genus of actinobacteria well known for their secondary metabolism, producing a large array of antibacterial, antifungal, and antiparasitic drugs. (berkeley.edu)
Metabolites1
- Antifungal Metabolites from Marine-Derived Streptomyces sp. (microbiologyjournal.org)
Echinocandins2
- New antifungals include the echinocandins (eg, caspofungin, micafungin) with pediatric dosing approved by the US Food and Drug Administration (FDA). (medscape.com)
- Even when there is a broad range of antifungals drugs for Candida infections, azoles, polyenes, and echinocandins are considered among the most effective treatment. (intechopen.com)
Isolates2
- In this study, 60 isolates of Streptomyces were isolated from wheat rhizosphere and screened in laboratory condition using dual culture. (ac.ir)
- In this study, about 112 isolates of Streptomyces were isolated from chickpea rhizospheric soils. (plantprotection.pl)
Strain3
- Streptomyces blastmyceticus strain 12-6 was isolated from a forest soil sample of Cheonan area on the basis of strong antifungal activities against plant pathogenic fungi. (koreamed.org)
- Keasling's team, comprised of JBEI and ABPDU scientists, studied the genes from the original strain ( S. roseoverticillatus) that encode the jawsamycin-building enzymes and took a deep dive into the genomes of related Streptomyces, looking for a combination of enzymes that could make a molecule with jawsamycin's toothy rings while skipping the other parts of the structure. (scienceblog.com)
- The Streptomyces globisporus SP6C4 strain and Streptomyces sp. (online-rpd.org)
Candida1
- But, EPSS5 displayed low antifungal activity against Candida albicans . (springeropen.com)
Bacteria4
- Well aware of the advantages biology has to offer, a group of biofuel experts led by Lawrence Berkeley National Laboratory (Berkeley Lab) took inspiration from an extraordinary antifungal molecule made by Streptomyces bacteria to develop a totally new type of fuel that has projected energy density greater than the most advanced heavy-duty fuels used today, including the rocket fuels used by NASA. (scienceblog.com)
- He had scoured the scientific literature for organic compounds with three-carbon rings and found just two known examples, both made by Streptomyces bacteria that are nearly impossible to grow in a lab environment. (scienceblog.com)
- A culture of the Streptomyces bacteria that makes the jawsamycin. (scienceblog.com)
- Various pigments like carotenes, melanins, flavones, quinines and violacein[ 4 - 6 ] are produced by different bacterial genera like Serratia , Streptomyces , Pseudomonas , Bacillus , Vibrio and Cytophyga that play an important role in their molecular and physiological processes and help taxonomist to identify and classify the bacteria, as they differ in chemical structure with specific chromophores. (ijpsonline.com)
Rimosus1
- S . rimosus , S . fumosus , S . albus and S . flavogriseus were able to produce chitinase, although the enzyme chitinase was found to be higher in Streptomyces albus . (springeropen.com)
Triazole3
- Itraconazole is a synthetic triazole antifungal agent that slows fungal cell growth by inhibiting CYP450-dependent synthesis of ergosterol, a vital component of fungal cell membranes. (medscape.com)
- Posaconazole is a triazole antifungal agent. (medscape.com)
- Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS. (lookformedical.com)
Marine-Derived3
- Cytotoxic and Antifungal Staurosporine Derivatives from Marine-derived Actinomycete Streptomyces sp. (bvsalud.org)
- 2-Epi-anthracimycin, a new cytotoxic agent from the marine-derived actinomycete Streptomyces sp. (kindai.ac.jp)
- Chlokamycin, a new chloride from the Marine-derived Streptomyces sp. (kindai.ac.jp)
Antiparasitic1
- [1] Members of this structural family have shown a wide range of biological activities like in antiparasitic, antifungal and anti-HIV evaluations, and furthermore, have shown potential usefulness because of their potent antibacterial properties. (wikimili.com)
Activity8
- Antifungal activity of biphenyls from streptomyces sp. (journalcra.com)
- Tunicamycin was first isolated from Streptomyces lysosuperificus based on its antiviral activity. (sigmaaldrich.com)
- Furthermore, gene overexpression is also frequently associated to antifungal resistance as well as an increase in the activity of proteins that reduce oxidative damage. (intechopen.com)
- Immunosuppressant and antifungal activity. (abcam.com)
- Immunosuppressant and antifungal activity in vitro and in vivo . (abcam.com)
- The antifungal activity of this drug depends, at least, in part, on its binding to a sterol moiety. (pharmacy180.com)
- While no antifungal activity has been detected against Aspergillus niger . (springeropen.com)
- Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS. (lookformedical.com)
Enzymes1
- used primers specific for ketosynthase (KS) domains and CYP450 enzymes to probe the DNA of Streptomyces sp. (wikimili.com)
Systemic1
- Itraconazole is an effective oral systemic antifungal, but is rarely used in pediatrics. (medscape.com)
Phytopathogenic fungi1
- Streptomyces albus has the highest ability to produce chitinase which can act as antifungal for degradation of the cell wall of many phytopathogenic fungi. (springeropen.com)
RDNA1
- با توجه به نتایج شناسایی مولکولی بر اساس توالی 16S rDNA، جدایه UTS22 متعلق به گونه Streptomyces fulvissimus بوده و به عنوان جدایه برتر در کنترل بیولوژیک B . sorokiniana معرفی میشود. (ac.ir)
Fluconazole1
- Fluconazole oral is a synthetic oral antifungal (broad-spectrum bistriazole) that selectively inhibits fungal CYP450 and sterol C-14 alpha-demethylation, which prevents conversion of lanosterol to ergosterol, thereby disrupting cellular membranes. (medscape.com)
Actinomycetes1
- Actinomycetes, particularly Streptomyces sp. (springeropen.com)
Agents5
- Candidal infections are sensitive to a broad range of antifungal agents. (medscape.com)
- Several molecular mechanisms with antifungal agents have been reported for C. albicans where insertions, deletions, and point mutations in genes codifying target proteins are frequently related to the antifungal drug resistance. (intechopen.com)
- This chapter summarizes the main molecular mechanisms to C. albicans antifungal drug resistance, besides offering an overview of new antifungal agents and new antifungal targets to combat fungal infections. (intechopen.com)
- Amphotericin B is an amphoteric, forming soluble salts in both basic and acidic environments, and due to extensive unsaturation, it is unstable, primarily used as antifungal agents. (pharmacy180.com)
- S8 have been reported as potent antifungal agents and are gaining attention for improving crop growth in sustainable agriculture. (online-rpd.org)
Fermentation1
- Natamycin (E235) is an anti-fungal compound produced by Streptomyces fermentation. (fredabiotech.com)
Yeast1
- Broad-spectrum antifungal agent that inhibits yeast growth by altering cell membrane permeability, causing fungal cells to die. (medscape.com)
Compound1
- The compound of interest in this project is physostigmine, produced by Streptomyces griseofuscus. (berkeley.edu)
Agent4
- A fungicidal allylamine antifungal agent. (medscape.com)
- A broad-spectrum azole antifungal agent. (medscape.com)
- It is an imidazole broad-spectrum antifungal agent. (medscape.com)
- Used as an antifungal agent. (pharmacy180.com)
Genetically1
- Fortunately, one of the molecules had been studied and genetically analyzed due to interest in its antifungal properties. (scienceblog.com)
Evaluation1
- Evaluation of Streptomyces spp. (plantprotection.pl)
Activities1
- Isolation, Identification and Antifungal Activities of Streptomyces spp from Various Soil Samples. (mtu.edu.mm)
Effect1
- The effect of environmental factors were determined on Streptomyces albus being the best chitinolytic producing isolate. (springeropen.com)