For example, a meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with depression. (wikipedia.org)
Venlafaxine, an antidepressant agent structurally and pharmacologically unrelated to other antidepressants and agents used to treat generalized anxiety disorder, is used to treat melancholia, generalized anxiety disorder (GAD), panic disorder, post-traumatic stress disorder, and hot flashes in breast cancer survivors. (illumina.com)
Multiple Meta-Analyses of New Generation Antidepressants (MANGA) Study Group None. (ox.ac.uk)
Thus, great hopes rest on the question whether the observed increase in NG following antidepression treatment may have the potential to become a novel drug target and specific mechanism in the development of the next generation of antidepressants that specifically involves targeting of neuropoetic factors in addition to their "traditional" effects as modulators of synaptic transmission. (johnshopkins.edu)
An AHRQ-sponsored report found that only 46% of patients experienced remission from depression during 6 to 12 weeks of treatment with second-generation antidepressants. (hireprowriter.com)
Amoxapine, the N -demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). (genelabs.com)
Therapeutic1
Although single drugs in one or two classes were available for the treatment of depression several decades ago, multiple therapeutic modalities now exist, often with many agents within each class. (beatcfsandfms.org)
Serotonin1
MCs can secrete nociceptor sensitizing and activating agents, such as serotonin, prostaglandins, histamine, and proteolytic enzymes that can also activate the pain-mediating transient receptor potential vanilloid channels. (frontiersin.org)
MeSH1
Antidepressive Agents, Second-Generation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
Clinical observations of the action profile of second-generation antipsychotic drugs in the treatment of schizophrenia have pointed to a possibility of these agents possessing mood-stabilizing properties. (nel.edu)
Antipsychotics2
However, the picture has changed following the introduction of second-generation antipsychotics. (nel.edu)
Most second-generation antipsychotics have demonstrated efficacy in the treatment of mania, both in monotherapy and as adjuncts to mood stabilizers. (elsevierpure.com)
Compounds2
As a consequence, oxidative stress arises from an imbalance between oxidant and antioxidant compounds in favor of excessive free radical generation. (hindawi.com)
Phytochemicals include compounds with various biological properties (i.e. antioxidant, antiproliferative, DNA repair) which have presumably evolved, in part, to allow plants to cope with environmental challenges including exposure to radiation and toxins, and defense against pests and infectious agents (Tuteja et al. (psychosocialsomatic.com)
Depression1
Depression is considered the major problem found in most of the individuals from this generation and it is said that around 16.1 million people suffer from depression in United States alone. (depressionandanxietytips.com)
Efficacy1
More careful assessment of the efficacy of an agent at early and regular intervals, with early revision of the treatment modality if it is not optimal, is an important new guideline that applies not only to somatic treatments, but also to psychotherapeutic approaches and combination psychotherapy-pharmacotherapy when treatment is not proceeding optimally. (beatcfsandfms.org)
Reaction1
According to Pashley, [3] products for in-office application are generally classified as those that do not polymerize, such as varnishes and precipitating agents, and those that undergo a setting reaction or polymerizing action, such as the conventional or resin-modified glass ionomer cements and resinous adhesives. (jdentlasers.org)
The study results showed that there was a significant reduction in sensitivity at the various time intervals with all the four desensitizing agents - glutaraldehyde in methacrylate resin (Gluma Desensitizer), nanofilled methacrylate resin (Seal and Protect), sodium fluoride varnish (Duraphat), and Er,Cr:YSGG laser therapy. (jdentlasers.org)
People2
This graph shows the total number of publications written about "Antidepressive Agents, Second-Generation" by people in this website by year, and whether "Antidepressive Agents, Second-Generation" was a major or minor topic of these publications. (uchicago.edu)
Below are the most recent publications written about "Antidepressive Agents, Second-Generation" by people in Profiles. (uchicago.edu)
Treatment1
Today, second- and third-generation treatment modalities are available. (beatcfsandfms.org)
Multiple1
The use of multiple agents appears to be superior to monotherapy in relapse prevention. (elsevierpure.com)
Oral tricyclic antidepressants and traditional anticonvulsants are better for short term pain relief than newer generation anticonvulsants. (bmj.com)
The biogenic amine transporters (BATs) regulate endogenous neurotransmitter concentrations and are targets for a broad range of therapeutic agents including selective serotonin reuptake inhibitors (SSRIs), serotonin-noradrenaline reuptake inhibitors (SNRIs) and tricyclic antidepressants (TCAs). (cornell.edu)
Second Generation1
T Polymorphism of the HTR2C Gene is Associated with Second Generation Antipsychotic-Induced Weight Gain in Female Patients with Schizophrenia. (cdc.gov)
SELECTION CRITERIA: All RCTs comparing fluoxetine with any other AD (including non-conventional agents such as hypericum) for patients with unipolar major depressive disorder (regardless of the diagnostic criteria used) were included. (ox.ac.uk)
Dopamine2
I took a look at the patent, as best as I could at present (not able to process it too well), and it is a use patent (as described by @Valentijn ) for 'dopamine stabilizing agents' (I was able to find an article about one of them, called '(−)-OSU6162', which is an experimental drug) in combination with just about any antidepressant you can think of. (phoenixrising.me)
Patients with anergic dysthymia, the authors suggest, may have a better response to treatment with agents that increase norepinephrine or dopamine. (medscape.com)
Medicine1
The root of this plant, which is yellow due to the presence of curcumin, has been used as a flavoring and coloring agent for food and medicine in Asian countries. (primal-state.de)
Terms1
Figure 3: Portion of list of terms for the PA search Antidepressive Agents pointing out the actual PA assignment for some terms. (nih.gov)
Effects2
Findings from the trial indicate that pelareorep and pembrolizumab synergize and show anti-cancer activity in these difficult-to-treat patients, which is mediated through the complementary immunotherapeutic effects of the two agents. (dailytimesleader.com)
The 2020 research article looked at the effects of cordyceps mushrooms on exercise performance in healthy mice and found that cordyceps aids ATP generation in mitochondrial cells. (honeblends.com)
Brain2
In addition, combination treatment of mice with risperidone and a monoamine reuptake inhibitor antidepressant imipramine or fluoxetine elicited larger increases in brain phospho-Ser-GSK3 than each agent alone. (researchgate.net)
various studies suggest that individually different brain states and networks are involved in the generation and perception of tinnitus. (cognitive-liberty.online)
Next generation2
In addition, the Branch provides training to develop the next generation of clinical translational researchers. (nih.gov)
For the next generation of chemical sensors, in addition to rapid qualitative and quantitative detection, it is also necessary to solve the problem of a distributed sensor power supply. (bvsalud.org)
Details1
The assessment of quality with the risk of bias tool revealed that the great majority of them failed to report methodological details, like the method of random sequence generation, the allocation concealment and blinding. (ox.ac.uk)