Antidepressive AgentsPlacebo EffectDepressive Disorder, Treatment-ResistantDepressive Disorder, MajorElectroconvulsive TherapyDepressive DisorderSubstance-Related DisordersSubstance Abuse Treatment CentersAntidepressive Agents, TricyclicResidential TreatmentAntidepressive Agents, Second-GenerationFluoxetineEating DisordersSerotonin Uptake InhibitorsCitalopramDrug ResistanceTreatment OutcomeImipramineDesipramineSertralineAntipsychotic AgentsCognitive TherapyDepressionCyclohexanolsNortriptylineParoxetineAmitriptylineMianserinPsychiatric Status Rating ScalesPhenelzineTranylcypromineAdrenergic Uptake InhibitorsAnxiety DisordersBipolar DisorderMood DisordersSwimmingMonoamine Oxidase InhibitorsDiagnostic and Statistical Manual of Mental DisordersSerotonin Plasma Membrane Transport ProteinsSuicideBrain-Derived Neurotrophic FactorClomipramineBupropionBrainPsychotherapyStress, PsychologicalAnhedoniaFluvoxamineDysthymic DisorderSerotoninBehavior, AnimalPersonality InventoryClinical Trials as TopicHelplessness, LearnedComorbidityMental DisordersHippocampusReceptor, Serotonin, 5-HT1AElectroshockTime FactorsAnxietyAnalysis of VarianceSeverity of Illness IndexZimeldineDouble-Blind MethodAffectRats, Sprague-DawleyBiogenic MonoaminesPsychotropic DrugsDothiepinReceptors, Serotonin, 5-HT1TrazodoneReceptors, SerotoninHypothalamo-Hypophyseal SystemRisk FactorsMaprotilineGyrus CinguliPharmacogeneticsBuspironeAnti-Anxiety AgentsDrug Therapy, CombinationFollow-Up StudiesPrefrontal CortexSuicide, AttemptedTupaiaPituitary-Adrenal SystemRecurrenceCorticosteroneMotor ActivityInterview, PsychologicalDose-Response Relationship, DrugDrug Administration ScheduleQuestionnairesAmygdalaFrontal LobeBenzodiazepinesEmotionsDisease Models, AnimalExploratory BehaviorUnited States