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  • Augmentation
  • TCAs may also be useful for those with comorbid attention deficit hyperactivity disorder (ADHD), enuresis, and narcolepsy, as well as for augmentation strategies. (medscape.com)
  • Mental Disorders
  • From scientists in research labs to CEOs at companies across the country, here's how one healthcare company is partnering with people from all walks of life to help drive change in how we treat mental disorders-and the stigma often associated with them. (justmeans.com)
  • See how @JNJNews is partnering with people from all walks of life to help drive change in how we treat mental disorders-and the stigma often associated with them. (justmeans.com)
  • This very lack of local resources is one of the reasons why 76 to 85% of people with serious mental disorders living in low- and middle-income countries have received no treatment, according to the World Health Organization . (justmeans.com)
  • Lifetime prevalence and age-of-onset distributions of mental disorders in the World Health Organization's World Mental Health Survey Initiative. (springer.com)
  • duration
  • Adequate duration is often defined as a minimum of 6 weeks, stemming from the observation that fewer than 7% of patients who show little improvement following 6 weeks of treatment with fluoxetine eventually respond (ie, show a 50% decrease in symptom severity) following an additional 2 weeks of treatment. (psychiatrictimes.com)
  • ketamine
  • One of the primary effects of ketamine in the brain is to block the NMDA [N-methyl-d-aspartate] glutamate receptor," said James W. Murrough, MD, principal investigator of the study, and Assistant Professor of Psychiatry and Neuroscience, and Associate Director of the Mood and Anxiety Disorders Program at the Icahn School of Medicine at Mount Sinai. (scienceblog.com)
  • Understand that this treatment requires a ketamine to be administered in a controlled manner. (scienceblog.com)
  • Ketamine - a glutamate N-methyl-d-aspartate (NMDA) receptor antagonist - has now been demonstrated in several studies to bring about a rapid and robust antidepressant effect, even in patients suffering from TRD. (clinicaltrials.gov)
  • Neurobiology
  • Study co-author Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai and President for Academic Affairs for the Mount Sinai Health System, and a world expert on the neurobiology and treatment of mood disorders, said: "What we have here is a proof of concept study and we consider the results very promising. (scienceblog.com)
  • rapid
  • The evidence of ketamine's rapid antidepressant effect is overwhelming, with researchers often saying this discovery is the most important medical breakthrough in over 50 years. (scienceblog.com)
  • psychotic
  • Smoking high-potency marijuana every day could increase the chances of developing psychosis by nearly five times, according to the biggest-ever study to examine the impact of pot on psychotic disorder rates. (thedailystar.net)