- If the findings are severe and recurrent, I might check for hypercoagulability with an antiphospholipid antibody panel. (the-hospitalist.org)
- as part of an evaluation for antiphospholipid antibody syndrome , as part of the evaluation of patients with connective tissue disease. (labtestsonline.org.uk)
- Antiphospholipid antibody tests are immune proteins ( antibodies ) directed against phospholipids. (labtestsonline.org.uk)
- When antiphospholipid antibodies are produced, they interfere with the clotting process in a way that is not fully understood. (labtestsonline.org.uk)
- Antiphospholipid antibodies are also associated with thrombocytopenia (low platelets) and with the risk of recurrent miscarriages (especially in the 2nd and 3rd trimester), premature labour, and pre-eclampsia . (labtestsonline.org.uk)
- Antiphospholipid antibodies are frequently seen with autoimmune disorders such as Systemic Lupus Erythematosus (SLE) . (labtestsonline.org.uk)
- Antiphospholipid syndrome (APS) , also called Hughes syndrome, is a recognised group of signs and symptoms that includes the formation of thrombi (blood clots), recurrent miscarriages, thrombocytopenia, and the presence of one or more antiphospholipid antibodies. (labtestsonline.org.uk)
- There are two types of tests that are used to detect antiphospholipid antibodies. (labtestsonline.org.uk)
- Positive HCV-antibody test with negative HCV RNA by polymerase chain reaction (PCR): Inform patients they do not have evidence of current (active) HCV infection. (medscape.com)
- Reinfection after previous spontaneous or treatment-related viral clearance: Obtain initial HCV-RNA testing (because an HCV-antibody test is expected to be positive). (medscape.com)
- A rapid antibody test for HCV is available. (medscape.com)
- The first is the test for cardiolipin or beta2 glycoprotein I antibodies. (labtestsonline.org.uk)
- But that was usually it unless there was something in the history or physical exam that would lead me to look for something less common - for example, cryoglobulins or an underlying hematologic disease that would lead to a predominance of lesions in acral sites. (the-hospitalist.org)
- They underwent clinical assessment and blood testing for factor V Leiden, prothrombin G20210A, methyltetrahydrofolate reductase C677T, plasminogen activator inhibitor type 1 (PAI-1) mutations, antithrombin, proteins C and S levels, and also antiphospholipid antibodies (anticardiolipin antibodies and lupus anticoagulant), cryoglobulins and cryoagglutinins. (nih.gov)
- [ 12 ] Laboratory abnormalities include elevated anticardiolipin antibodies, sedimentation rate, blood pressure, and creatinine as well as a mild leukocytosis and eosinophilia. (medscape.com)
- The prevalences of factor V Leiden, prothrombin G20210A, elevated titer of antiphospholipid antibodies and the presence of cryoglobulins were higher in the early onset group, although the differences were not statistically significant. (nih.gov)