AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Antibodies, MonoclonalLymphocytesAntibodiesLymphocyte ActivationT-LymphocytesAntibody SpecificityAntibodies, ViralAntibodies, BacterialAntibody FormationT-Lymphocytes, CytotoxicAntibodies, NeutralizingB-LymphocytesLymphocyte SubsetsEpitopesLymphocyte CountFluorescent Antibody TechniqueCD4-Positive T-LymphocytesCytotoxicity, ImmunologicCells, CulturedMice, Inbred BALB CAntibody AffinityBinding Sites, AntibodyAntibodies, Anti-IdiotypicSpleenFlow CytometryCD8-Positive T-LymphocytesMolecular Sequence DataAntigens, CD3Interleukin-2T-Lymphocyte SubsetsMice, Inbred C57BLLymphocyte Culture Test, MixedImmunoglobulin MPhytohemagglutininsAntigens, CDCross ReactionsAntigens, SurfaceCell LineHIV AntibodiesAmino Acid SequenceAntibodies, NeoplasmLymphocytes, Tumor-InfiltratingAntibodies, AntinuclearAntibodies, ProtozoanAntigens, Differentiation, T-LymphocyteInterferon-gammaImmunity, CellularImmunoglobulin GConcanavalin AReceptors, Antigen, T-CellLeukocyte CountAntigensClone CellsAntigen-Antibody ReactionsAutoantibodiesCytotoxicity Tests, ImmunologicAntigens, NeoplasmThymus GlandImmunizationLymph NodesJurkat CellsLymphocyte DepletionKiller Cells, NaturalLymphocyte CooperationImmunophenotypingMembrane GlycoproteinsNeutralization TestsLymphocyte TransfusionAntigens, ViralAntibodies, BlockingRosette FormationMitogensImmunoglobulinsMice, Inbred StrainsCytokinesAntibodies, FungalBase SequenceAntigen-Antibody ComplexImmune SeraCell SeparationRecombinant ProteinsAntigens, CD4Time FactorsHIV-1HybridomasCell DivisionAntibodies, BispecificImmunization, PassiveT-Lymphocytes, Helper-InducerImmunologic MemoryEnzyme-Linked Immunosorbent AssayLymphocyte Function-Associated Antigen-1Immunoglobulin ARabbitsImmunohistochemistryImmunoglobulin Fab FragmentsMacrophagesImmunoenzyme TechniquesMonocytesAntigens, CD45
MONOCLONAL ANTIBODIESAntigensWhite blood cells called lymphImmunoglobulinSubsetsMixed lymphocyte cultureMake antibodiesMain types of lymphocytesCellsAssayTumor-infiltratinRecombinantHuman lymphocytesBinding to an antigenCD20SerumImmunityBone marrowProliferationMonocytesSuppressesRheumatoidStimulationImmunoglobulinsLymphomaResponsesSpecimensMoleculeSurfaceThymusLymphaticSecretionsAutologousInfectionCytotoxicityCellPeptidesActivationAbstractAssaysMacrophageMiceCharacterizationInvaderReactivityProteinReactAzideCytokinesLymphoidEnumerationAdaptive immuneImmune System
MONOCLONAL ANTIBODIES8
  • With the help of new monoclonal antibodies against mouse LAG-3, we show that LAG-3 surface expression is not limited to activated T and NK cells but is also found on activated B cells. (nih.gov)
  • Identification of HLA-DP polymorphism with DP alpha and DP beta probes and monoclonal antibodies: correlation with primed lymphocyte typing. (ox.ac.uk)
  • The value of monoclonal antibodies for such studies is demonstrated, and the molecular data can, in some cases, pinpoint the amino acids responsible for the specificity of the monoclonal antibodies. (ox.ac.uk)
  • Immunophenotyping relies on detecting specific antigenic determinants on the surface of WBCs by antigen-specific monoclonal antibodies that have been labeled with a fluorescent dye or fluorochrome, such as phycoerythrin (PE) or fluorescein isothiocyanate (FITC). (cdc.gov)
  • How Do Anti-CD20 Monoclonal Antibodies Work? (rxlist.com)
  • Anti-CD20 monoclonal antibodies are administered as a solution (liquid) to be added to fluid and injected intravenously (into a vein). (rxlist.com)
  • Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. (abcam.com)
  • Monoclonal antibodies and T-cell hybridomas : perspectives and technical advances / editors, Günter J. Hämmerling, Ulrich Hämmerling and John F. Kearney. (who.int)
Antigens11
  • The principle is based on the secretion of antibody from in vivo activated plasma B cells found in blood circulation for a short period of time in response to TB-antigens during active TB infection rather than latent TB infection. (wikipedia.org)
  • The position of bands on the nitrocellulose strips allows this antibody reactivity to be associated with specific viral antigens. (cdc.gov)
  • Studies with panels of allogeneic normal B cells and of HLA homozygous B-cell lines showed that the target antigen(s) recognized by these antibodies is clearly distinct from HLA-D antigens. (ox.ac.uk)
  • Corresponding antigens seem to be expressed on placenta, since the lymphocytotoxic antibodies could be absorbed out with trophoblastic homogenates and one serum reacted with JAR cells (cultured choriocarcinoma line). (ox.ac.uk)
  • To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. (wikipedia.org)
  • Acquired immunity comes from antibodies you get from your mother in the womb or that you make in response to antigens that aren't yours -- like from a cold virus or a vaccine. (webmd.com)
  • Secreted antibodies bind to antigens on the surfaces of invading microbes (such as viruses or bacteria), which flags them for destruction. (newworldencyclopedia.org)
  • Thirty-four lymphoblastoid cell lines that had been previously typed for HLA-DP antigens by primed lymphocyte typing (PLT) were tested by Southern blotting and by ELISA. (ox.ac.uk)
  • They destroy antigens tagged by antibodies or cells that are infected or somehow changed. (kidshealth.org)
  • T lymphocytes are responsible for cell-mediated immunity , so named because the T cells themselves latch onto the antigens of the invader and then initiate reactions that lead to the destruction of the nonself matter. (britannica.com)
  • Lymphocytes enable the body to remember antigens and to distinguish self from harmful nonself (including viruses and bacteria). (msdmanuals.com)
White blood cells called lymph1
  • This enzyme is found throughout the body but is most active in specialized white blood cells called lymphocytes. (medlineplus.gov)
Immunoglobulin4
  • An antibody ( Ab ), also known as an immunoglobulin ( Ig ), [1] is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses . (wikipedia.org)
  • Antibodies are glycoproteins belonging to the immunoglobulin superfamily . (wikipedia.org)
  • The terms antibody and immunoglobulin are often used interchangeably, [1] though the term 'antibody' is sometimes reserved for the secreted, soluble form, i.e. excluding B-cell receptors. (wikipedia.org)
  • An antibody can also be called immunoglobulin or Ig. (webmd.com)
Subsets4
  • CD4+ T-cells and other lymphocyte subsets in persons infected with human immunodeficiency virus (HIV). (cdc.gov)
  • The guidelines describe single-platform technology (SPT), a process in which absolute counts of lymphocyte subsets are measured from a single tube by a single instrument. (cdc.gov)
  • With CD45 gating, the relative numbers of beads and lymphocyte subsets are enumerated, and their absolute numbers and percentage values are calculated. (cdc.gov)
  • The aim of our research was to determine how immunotherapy changes the proportion of lymphocyte subsets in dog peripheral blood and the levels of cytokines secreted by these cells during therapy. (mdpi.com)
Mixed lymphocyte culture2
  • Blocking antibody directed against donor responding cells has been found to develop in HL-A-mixed lymphocyte culture-identical donor-recipient combinations after renal transplantation in which splenectomy was not perfortned. (northwestern.edu)
  • Cytotoxic antibody associated with rejection episodes and detected only by the discriminatory mixed lymphocyte culture developed in other HL-A-mixed lymphocyte culture-identical combinations as well. (northwestern.edu)
Make antibodies4
Main types of lymphocytes1
Cells46
  • HIV infection is characterized by a decrease and, eventually, a depletion of CD4+ T-lymphocytes (helper T cells). (cdc.gov)
  • Using immunophenotyping, HIV-positive blood samples and age-matched controls were tested for the proportion of lymphocytes that are T cells, B cells, natural killer (NK) cells, CD4+ T cells (helper T cells), and CD8+ T cells (suppressor/inducer T cells). (cdc.gov)
  • The functional activity of this T lymphocyte subpopulation is a matter of discussion and has to be clarified by functional studies of purified populations of these cells. (rug.nl)
  • A type of T cell called killer T lymphocytes bind to the pathogen and produce cytotoxin that destroys cells. (scienceaid.net)
  • A large number of cloned B cells secrete antibodies that kill the microorganism. (scienceaid.net)
  • Lymphocyte activation gene 3 (LAG-3/CD223) is a CD4 homolog known to be selectively expressed in activated T and NK cells. (nih.gov)
  • Anti‐DNA antibody synthesis in response to DNA was T‐dependent, and the experiments with reconstituted lymphocytes from identical twins discordant for SLE showed that B cells and T cells from SLE patients must cooperate to synthesize anti‐DNA antibody. (elsevierpure.com)
  • Anti‐DNA antibody synthesis by lymphocytes from patients with inactive SLE was enhanced by T4 cells and suppressed by T8 cells in response to DNA. (elsevierpure.com)
  • Although T4 cells from patients with active SLE could enhance anti‐DNA antibody synthesis by autologous B cells, their T8 cells could not suppress anti‐DNA antibody synthesis by autologous B cells. (elsevierpure.com)
  • These results indicate that elevated anti‐DNA antibody synthesis in response to DNA in patients with active SLE is due to abnormalities of both SLE B cells and SLE T cells. (elsevierpure.com)
  • They further indicate that dysfunction of T8 cells from patients with active SLE may, in part, be responsible for deficient regulation of anti‐DNA antibody synthesis. (elsevierpure.com)
  • Together with B and T cells , antibodies comprise the most important part of the adaptive immune system . (wikipedia.org)
  • After an antigen binds to a BCR, the B cell activates to proliferate and differentiate into either plasma cells , which secrete soluble antibodies with the same paratope, or memory B cells , which survive in the body to enable long-lasting immunity to the antigen. (wikipedia.org)
  • Lymphocytes called T cells and B cells work together to build your acquired immunity. (webmd.com)
  • CONCLUSIONS: Murine studies suggest that measures of T-lymphocyte activity (particularly CD4 and CD8 T cells) may be predictive biomarkers of severity. (ox.ac.uk)
  • Other lymphocyte-like cells are commonly known as natural killer cells, or NK cells, and are part of the innate immune system . (newworldencyclopedia.org)
  • The NK cells are sometimes labeled "large granular lymphocytes," while the T cells and B cells are labeled as "small lymphocytes. (newworldencyclopedia.org)
  • While offering protection against millions of possible invaders, including viruses , bacteria , are cancer cells, lymphocytes allow normal body cells and helpful, symbiotic bacteria to flourish at the same time. (newworldencyclopedia.org)
  • A stained lymphocyte surrounded by red blood cells viewed using a light microscope. (newworldencyclopedia.org)
  • The two main categories of lymphocytes are the B lymphocytes ( B cells ) and T lymphocytes ( T cell ), both of which are involved in the adaptive immune system (Alberts 1989). (newworldencyclopedia.org)
  • B cells specifically are involved in the humoral immune system and produce antibodies , while T cells are involved in the cell-mediated immune system and destroy virus-infected cells and regulate the activities of other white blood cells (Alberts 1989). (newworldencyclopedia.org)
  • B cells respond to pathogens by producing large quantities of antibodies that then neutralize foreign objects like bacteria and viruses . (newworldencyclopedia.org)
  • In addition, lymphocyte-like cells called natural killer (NK) cells are involved in the immune system, albeit part of the innate immune system . (newworldencyclopedia.org)
  • The humoral immune system acts against bacteria and viruses in the body liquids (e.g., blood ) by means of proteins called immunoglobulins (also known as antibodies ), which are produced by B cells. (newworldencyclopedia.org)
  • Simultaneously, RAW 264.7 and MLE-15 cells were treated with SWCNT (24 hours, 6 microg/cm2 to 48 microg/cm2) or bleomycin (0.1 microg/ml) in the presence of OPN-blocking antibody or isotype control and TGF-beta1 was measured in supernatants. (cdc.gov)
  • RAW 264.7 and MLE-15 cells exposed to SWCNT and bleomycin had significantly less TGF-beta1 released in the presence of OPN-blocking antibody. (cdc.gov)
  • Further evidence that the 2.4G2 IgG was directed against FcRII came from binding studies of the monoclonal antibody to J774 cells and a series of independently isolated variants which do not express FcRII. (silverchair.com)
  • IgG antibody producing cells are strongly positive for the J11d. (atcc.org)
  • The antibody does not react with mature (medullary) thymocytes, pluripotential stem cells, platelets or cells of monocyte-macrophage lineage. (atcc.org)
  • Amplifier T cells responsible for enhancement of the antibody response to type III pneumococcal polysaccharide have been shown to be resistant to the effects of antilymphocyte serum (ALS) given at the time of immunization, a treatment that eliminates suppressor T cell activity. (johnshopkins.edu)
  • Lymphocytes start out in the bone marrow and either stay there and mature into B cells, or go to the thymus gland to mature into T cells. (kidshealth.org)
  • B lymphocytes, the immune cells that secrete antibodies, follow this pattern. (sciencedaily.com)
  • No vaccine trial to date," he said, "has been able to produce significant numbers of memory T lymphocytes, which are important in killing HIV-infected or cancerous cells. (sciencedaily.com)
  • 50%), compact MC infiltrates are accompanied by perifocal clusters of lymphocytes containing a mixture of B and T cells. (bmj.com)
  • The key cells of the immune system are the white blood cells known as lymphocytes. (britannica.com)
  • and the percentage of lymphocytes that are CD4+ T-cells. (cdc.gov)
  • Anti-CD20 antibodies attach to the CD20 receptor and cause the tumor cells to disintegrate (lyse). (rxlist.com)
  • MPA prevents the glycosylation of lymphocyte and monocyte glycoproteins that are involved in intercellular adhesion to endothelial cells and may inhibit recruitment of leukocytes into sites of inflammation and graft rejection. (nih.gov)
  • Flow Cytometry: HLA DRB1 Antibody (LN-3 + HLA-DRB/1067) [NBP2-45316] - Flow Cytometric Analysis of Human Raji cells using HLA DRB1 Antibody (LN-3 + HLA-DRB/1067). (novusbio.com)
  • The immune system can remember every antigen encountered because after an encounter, some lymphocytes develop into memory cells. (msdmanuals.com)
  • Lymphocyte immune globulin inhibits the cell-mediated immune response by altering T-cell function or by eliminating antigen-reactive cells. (medscape.com)
  • Lymphoma is a type of cancer that affects your blood cells called lymphocytes. (lymphoma.org.au)
  • Our lymphocytes are white blood cells that are a big part of our immune system. (lymphoma.org.au)
  • Unlike our other blood cells, lymphocytes usually live in our lymphatic system rather than in our blood stream. (lymphoma.org.au)
  • Some rare lymphomas are Natural Killer cell (NK) lymphomas - NK cells are a type of T-cell lymphocyte. (lymphoma.org.au)
  • Non-Hodgkin Lymphoma (NHL) - these are lymphomas of all other B-cells or T-cell lymphocytes, including NK cells. (lymphoma.org.au)
Assay4
  • The antibodies from lymphocyte secretions (ALS) assay is an immunological assay to detect active diseases like tuberculosis, cholera, typhoid etc. (wikipedia.org)
  • The antibodies from lymphocyte secretion (ALS) assay was earlier used to detect specific antibody response after oral vaccination with a killed cholera vaccine in healthy adults without any requirement for in vitro antigen stimulation. (wikipedia.org)
  • Development of a novel in vitro assay (ALS assay) for evaluation of vaccine-induced antibody secretion from circulating mucosal lymphocytes. (wikipedia.org)
  • We harvested peripheral blood lymphocytes and analyzed antibody levels in supernatants collected on days 0, 5, and 20 (using an antibody-in-lymphocyte-supernatant [ALS] assay), as well as in plasma on these days. (wustl.edu)
Tumor-infiltratin3
  • Adoptive cell therapy using tumor-infiltrating lymphocytes (TILs) has shown activity in melanoma, but has not been previously evaluated in metastatic non-small cell lung cancer. (nature.com)
  • PD-L1 IHC positivity and abundance of tumor infiltrating lymphocytes were of positive prognostic value in univariable regression analyses in patients treated with (neo)adjuvant chemotherapy, where it was strongest for 22C3 CPS ≥ 10 and distant relapse-free interval (HR = 0.18, p = 0.019). (lu.se)
  • However, PD-L1 status was not independently prognostic when adjusting for abundance of tumor infiltrating lymphocytes in multivariable analyses. (lu.se)
Recombinant2
  • They are man-made antibody that was developed using cloning and recombinant DNA technology from human and murine (mice or rat) genes and work by inhibiting early-stage B lymphocyte activation. (rxlist.com)
  • Alemtuzumab is a recombinant monoclonal antibody against CD52 (lymphocyte antigen). (medscape.com)
Human lymphocytes1
Binding to an antigen1
  • The class hence determines the function triggered by an antibody after binding to an antigen, in addition to some structural features. (wikipedia.org)
CD204
  • History Rituximab an anti-CD20 antibody effectively depletes B lymphocytes. (techuniq.com)
  • In the 2000s rituximab a chimeric monoclonal antibody against the protein CD20 which is definitely primarily found on the surface of B lymphocytes was launched for the management of ABO-IKT [3 4 This protocol has become standard in multiple centers after Tydén et al. (techuniq.com)
  • 5] 1st launched antigen-specific immunoabsorption combined with anti-CD20 antibody and Sonnenday et al. (techuniq.com)
  • 6] reported successful ABO-IKT using plasmapheresis cytomegalovirus (CMV) hyperimmune globulin and anti-CD20 antibody without splenectomy. (techuniq.com)
Serum2
  • The Cambridge Biotech HIV-1 Western Blot Kit, when used as directed, will detect antibodies to HIV-1 when present in human serum or plasma. (cdc.gov)
  • The PubMed, Zoological Record, and Embase databases were screened from January 1980 to May 2018 to identify animal studies of RSV infection that assessed serum antibody titer or T lymphocytes with disease severity as an outcome. (ox.ac.uk)
Immunity3
  • We now move in to look at specific immunity and the role of the T lymphocytes . (scienceaid.net)
  • Because these fluids were traditionally known as humors , antibody-mediated immunity is sometimes known as, or considered a part of, humoral immunity . (wikipedia.org)
  • For example, antibodies in a mother's breast milk give a baby temporary immunity to diseases the mother has been exposed to. (kidshealth.org)
Bone marrow4
  • B lymphocytes are also made in the bone marrow and mature in lymph nodes where they acquire membrane receptors. (scienceaid.net)
  • Increase of bone marrow lymphocytes in systemic mastocytosis: reactive lymphocytosis or malignant lymphoma? (bmj.com)
  • To clarify the nature (reactive or neoplastic) of lesional, perifocally aggregated lymphocytes in bone marrow infiltrates of systemic mastocytosis (SM), the histopathology of which can resemble malignant lymphoma with focal bone marrow involvement, particularly low grade malignant B cell lymphoma of lymphoplasmacytic immunocytoma subtype, which frequently exhibits increased mast cell (MC) numbers. (bmj.com)
  • Focal accumulations of lymphocytes in the bone marrow of SM are reactive in nature and could be termed lymphocytosis. (bmj.com)
Proliferation3
  • Heterogeneity of inhibition of cytolytic T lymphocyte clones by monoclonal anti-Lyt-2/3 antibodies: parallel effects on cytolysis, proliferation and lymphokine secretion. (ox.ac.uk)
  • Because T- and B-lymphocytes are critically dependent for their proliferation on de novo synthesis of purines, whereas other cell types can utilize salvage pathways, MPA has potent cytostatic effects on lymphocytes. (nih.gov)
  • This antigen is involved in B-lymphocyte activation and proliferation. (beckman.com)
Monocytes1
Suppresses3
Rheumatoid1
  • Laboratory tests such as complete blood count with differential, complete metabolic panel, erythrocyte sedimentation rate and C-reactive protein, antinuclear antibody, rheumatoid factor , lipid panel, thyroid-stimulating hormone , and celiac screen should all be performed to investigate symptoms, but are often unhelpful. (medscape.com)
Stimulation2
  • MPA inhibits proliferative responses of T- and B-lymphocytes to both mitogenic and allospecific stimulation. (nih.gov)
  • Antigen stimulation of lymphocytes induces CD229 clustering to sites of T cell‑B cell contact (7). (rndsystems.com)
Immunoglobulins1
Lymphoma1
Responses3
  • We aimed to review the role of antibody and T-cell responses in relation to RSV disease severity in animals. (ox.ac.uk)
  • METHODS: Systematic review and meta-analysis of animal studies examining the association between T-cell responses/phenotype or antibody titers and severity of RSV disease. (ox.ac.uk)
  • Immunosuppressive, delayed hypersensitivity, and cellular cytotoxicity tests are suppressed to a greater degree than antibody responses. (medscape.com)
Specimens2
  • All specimens were tested using the Synthetic Peptide Enzyme Immunoassay (EIA) (Genetic Systems HIV-1/HIV-2 Peptide EIA) for the detection of antibody to human immunodeficiency virus type 1 or type 2 (HIV-1 and HIV-2) or both (Bio-Rad Laboratories, Hercules, CA). Any specimen that reacted in an initial test was retested in duplicate with the Genetic Systems HIV-1/HIV-2 Peptide EIA. (cdc.gov)
  • All specimens were tested using the Synthetic Peptide Enzyme Immunoassay (EIA) (Genetic Systems HIV-1/HIV-2 Peptide EIA) for the detection of antibody to human immunodeficiency virus type 1 or type 2 (HIV-1 or HIV-2) or both (Bio-Rad Laboratories, Redmond, WA). (cdc.gov)
Molecule2
  • Adenosine deaminase converts deoxyadenosine, which can be toxic to lymphocytes, to another molecule called deoxyinosine that is not harmful. (medlineplus.gov)
  • The antibody recognizes a unique molecule of the pathogen, called an antigen . (wikipedia.org)
Surface2
  • They were shown to react mainly with surface Ig (SIg) bearing lymphocytes, plus a minor SIg negative subset. (ox.ac.uk)
  • Initially, all antibodies are of the first form, attached to the surface of a B cell - these are then referred to as B-cell receptors (BCR). (wikipedia.org)
Thymus2
Lymphatic2
Secretions2
Autologous1
Infection3
  • A mathematical model and CD4+ lymphocyte dynamics in HIV infection. (cdc.gov)
  • Lymphocytes are a type of white blood cell that support our immune system by fighting infection and disease. (lymphoma.org.au)
  • Because our lymphocytes fight infection and disease, they are part of our immune system. (lymphoma.org.au)
Cytotoxicity1
  • These findings are taken to be strong evidence in favor of qualitatively demonstrable separate antibody molecules dealing with two separate functions, i.e., cytotoxicity versus enhancement or immunoregulation. (northwestern.edu)
Cell12
  • The Cambridge Biotech HIV-1 Western Blot Kit is manufactured by Calypte Corporation from HIV-I propagated in an H9/HTLV-IIIb T-lymphocyte cell line. (cdc.gov)
  • REACTIVITY OF PRESUMED ANTI-NATURAL KILLER CELL ANTIBODY LEU-7 WITH INTRAFOLLICULAR LYMPHOCYTES-T . Clinical and Experimental Immunology , 54 (3), 834-837. (rug.nl)
  • These antibodies exhibited a maximal cytotoxic activity at +4 degrees C. They reacted mainly with B lymphocytes as assessed by microlymphocytotoxicity assays using B- or T-cell enriched subpopulations and T- or B-cell lines as targets. (ox.ac.uk)
  • Using this binding mechanism, an antibody can tag a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). (wikipedia.org)
  • A lymphocyte is a type of white blood cell (leukocyte) in the vertebrate immune system . (newworldencyclopedia.org)
  • These variants of J774 bound 5% as much of the monoclonal antibody as the parent line, which bound 600,000 molecules of 2.4G2 IgG per cell. (silverchair.com)
  • The antigenic relatedness of mouse lymphocyte FcR to mouse macrophage FcRII was demonstrated by the binding of 2.4G2 IgG to FcR-bearing lymphoid cell lines and the inhibition of the lymphocyte FcR by the monoclonal antibody. (silverchair.com)
  • One requires two parallel tracks for cell-killing T lymphocytes. (sciencedaily.com)
  • The overall objective of EuroNeut-41 was to design a vaccine that raises antibodies able to prevent HIV cell fusion by blocking the virus fusion protein gp41 in its pre-fusogenic conformation. (europa.eu)
  • A scanning electron micrograph of a human T lymphocyte (or T cell) from the immune system of a healthy person. (britannica.com)
  • Western Blot: HLA DRB1 Antibody (LN-3 + HLA-DRB/1067) [NBP2-45316] - Western Blot Analysis of Ramos cell lysate using HLA DRB1 Antibody (LN-3 + HLA-DRB/1067). (novusbio.com)
  • T-cell lymphocytes. (lymphoma.org.au)
Peptides1
  • The most promising Ags were submitted to a more in-depth biophysical investigation of their structure and conformation stability, and for their capacity to interact with neutralising antibodies (Abs) and peptides. (europa.eu)
Activation1
  • Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. (nature.com)
Abstract2
  • abstract = "This report describes the presence of a T lymphocyte subpopulation in germinal centres of lymph follicles. (rug.nl)
  • abstract = "The cellular mechanism of anti‐DNA antibody synthesis in patients with systemic lupus erythematosus (SLE) was studied by DNA‐specific solid‐phase radioimmunoassay. (elsevierpure.com)
Assays1
  • This document has been developed by CDC to give guidance to laboratories performing lymphocyte immunophenotyping assays in human immunodeficiency virus-infected persons. (cdc.gov)
Macrophage2
  • Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. (silverchair.com)
  • To investigate the antigenic relationship between the macrophage and lymphocyte Fc receptors (FcR), a monoclonal antibody capable of blocking mouse macrophage Fc receptors was selected. (silverchair.com)
Mice2
  • RESULTS: RSV-specific antibody appears to protect from disease in mice, but such an effect was less evident in bovine RSV. (ox.ac.uk)
  • Treated mice developed antibodies and lymphocytes against SARS-CoV2. (unige.ch)
Characterization1
Invader1
Reactivity1
  • This subpopulation is defined by reactivity with Leu 7 antibody, in addition to OKT11, OKT1, OKT3 and OKT4 positivity. (rug.nl)
Protein1
  • 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. (novusbio.com)
React1
  • Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. (abcam.com)
Azide2
Cytokines1
  • This technology therefore allows the stable and sustained long-term production and release of proteins such as cytokines or antibodies. (unige.ch)
Lymphoid2
Enumeration1
  • Enumeration of CD4+ lymphocytes in HIV-positive participants and age-matched controls was performed on cryopreserved whole blood using the method reported by Fiebig et. (cdc.gov)
Adaptive immune1
Immune System2
  • The constant region at the trunk of the antibody includes sites involved in interactions with other components of the immune system. (wikipedia.org)
  • An antigen is any substance that causes the immune system to produce antibodies. (newworldencyclopedia.org)