ChromograninImmunohistochemistryCytoplasmicImmunohistochemicalIsotypeNeuronsMarkerNeuroendocrineTumorProteinEpithelialCytokeratinMarkersClinicalMinimalClinicallySecondaryTumorsCocktailSupplierProteinsMajorClassificationSufferersImmuneQualityHighestPrimaryHighServicesSimilarFoundMainResearchSmallCells
Chromogranin7
- At the end of the experiment, animals were euthanized and autopsies were performed, with routine histopathological examination and immunohistochemical study with antibodies to human chromogranin A, synaptophysin, and the marker of proliferative activity (Ki-67) of both original donor tumor and orthotopic pancreatic and liver xenografts. (almclinmed.ru)
- At immunohistochemical assessment, the patient's primary and metastatic tumor tissue specimens expressed anti-chromogranin A (full-blown cytoplasmic reaction) and anti-synaptophysin (mild cytoplasmic reaction) antibodies. (almclinmed.ru)
- An immunohistochemical study of the orthotopic tumor fragments and heterotopic tumor fragments showed moderate cytoplasmic staining with antibodies to chromogranin A and synaptophysin. (almclinmed.ru)
- Immunoperoxidase staining of a human pancreas cryosection with Mouse anti Human chromogranin A antibody, clone LK2H10 ( MCA5696 ). (bio-rad-antibodies.com)
- Mouse anti Human Chromogranin A antibody, clone LK2H10 specifically recognizes chromogranin A (CgA), a secretory glycoprotein and member of the chromogranin/secretogranin family, widely expressed by cells of the neuroendocrine system and related tumours, which is used in immunohistochemistry as a valuable diagnostic marker for pheochromocytomas, paragangliomas and carcinoid, pancreatic and prostate tumours. (bio-rad-antibodies.com)
- Previously described as the cholangioblastic variant of intrahepatic cholangiocarcinoma, these tumors are described as having varied architectural patterns, biphasic cytology (large eosinophilic and small basophilic cells), and diffuse reactivity to both cytokeratin 7 and inhibin A. In the current report, all tumors also demonstrated patchy reactivity to synaptophysin and chromogranin. (hanspopperhepatopathologysociety.org)
- The authors caution against a pitfall of calling this tumor neuroendocrine in nature based on the synaptophysin/chromogranin staining. (hanspopperhepatopathologysociety.org)
Immunohistochemistry4
- Ototoxicity was assessed by measuring frequency specific ABR thresholds before and 96 h after treatment, loss of inner (IHCs) and outer (OHCs) hair cells, and by performing densitometry-based immunohistochemistry analysis of cochlear synaptophysin, organic transporter 2 (OCT2), and copper transporter 1 (CTR1) at 12 and 7 mm from the round window. (frontiersin.org)
- 17. Effectiveness of computer-aided diagnosis (CADx) of breast pathology using immunohistochemistry results of core needle biopsy samples for synaptophysin, oestrogen receptor and CK14/p63 for classification of epithelial proliferative lesions of the breast. (nih.gov)
- Immunohistochemistry was optimistic for neural cell adhesion molecule CD56 and synaptophysin, which was indicative of neuroendocrine origin. (inacj.com)
- Multiplex immunohistochemistry was utilized utilizing antibodies in opposition to CD66b, CD8, CD20, FoxP3, CD68 and pan - Cytokeratin . (inacj.com)
Cytoplasmic2
- Membrane cytoplasmic and nuclear blots were incubated with appropriate HRP-conjugated secondary antibodies (Bio-Rad) and visualized using a chemiluminescence reaction (Amersham Piscataway NJ) recognized by X-ray autoradiography (Biomax Chemiluniscence Film Kodak Rochester NY). (techblessing.com)
- All had cytoplasmic expression of synaptophysin and insulin however had been immunonegative for glucagon, confirming a purposeful analysis of canine insulinoma. (influenza-x.org)
Immunohistochemical1
- The Function of a Minimal Immunohistochemical Antibody Panel in Confirming Undifferentiated Nasopharyngeal Carcinoma: A Cross-Sectional Research on the Muhimbili Nationwide Hospital, Dar-es-Salaam, Tanzania. (inacj.com)
Isotype3
- Littermate control wild-type and APP/PS1 mice were tail vein injected with either saline, isotype control (IgG2b), or an antibody recognizing α4-integrin, anti-CD49d, once a week for 4 consecutive weeks. (nih.gov)
- Our data suggests that the antibody therapy was able to reduce microgliosis, astrogliosis, and synaptic changes in the APP/PS1 mice compared to isotype control injections without changing amyloid-β plaque load. (nih.gov)
- Interestingly, both isotype control and antibody therapy also reduced the number of proinflammatory cytokines in the spleen although changes in the brain were less robust. (nih.gov)
Neurons1
- Subcortical white matter neurons were identified with antibodies to MAP2, a cytoskeletal protein enriched in dendrites and somas of mature neurons. (medscape.com)
Marker2
- 2. Usefulness of immunocytochemistry using a Breast Marker antibody cocktail targeting P63/cytokeratin7/18/cytokeratin5/14 for fine needle aspiration of the breast: a retrospective cohort study of 139 cases. (nih.gov)
- cells are express and synaptophysin-negative pRb, the epithelial cell marker cytokeratin that's portrayed in the retinal pigmented epithelium as well as the vascular endothelial cell marker Compact disc34. (monossabios.com)
Neuroendocrine1
- One main tumour was recognized as a combined neuroendocrine-non-neuroendocrine neoplasm, which is the primary report of this neoplasm in canines. (influenza-x.org)
Tumor2
- Eight major groups of lung carcinomas are recognized in WHO-2004: Squamous cell lung carcinoma Small cell lung carcinoma Adenocarcinoma of the lung Large cell lung carcinoma Adenosquamous carcinoma Sarcomatoid carcinoma Carcinoid tumor Salivary gland-like carcinoma of the lung LCLC-RP are considered variants of large cell carcinoma. (wikipedia.org)
- Orthotopic patient-derived xenografts (PDX) in immunodeficient mice are recognized as the most adequate neoplastic model due to their ability to maintain primary tumor properties after implantation. (almclinmed.ru)
Protein6
- 1997 Pre- and post-synaptic protein such as for example synaptophysin and drebrin respectively are indicated in synaptic vesicles with dendrites (Aoki GKA50 et al. (techblessing.com)
- Individual cytosolic protein blots were incubated with main antibodies (1:500 dilution) for IL-1β TNFα CD11b GFAP iNOS cPLA2-IVA sPLA2-IIA iPLA2-VIA COX-1 COX-2 5 12 and 15-LOX m-PGES-1 (1:200) cPGES synaptophysin drebrin (Abcam Cambridge MA) or tubulin (Cell Signaling). (techblessing.com)
- 8, 15, 16] Antibodies for the major MCPyV capsid protein (VP1) are associated with MCPyV infection, which is asymptomatic and the prevalence of which increases with age. (medscape.com)
- Most importantly, it must be able to recognize the target protein in its native chromatin-associated context after fixation. (thp.at)
- A primary antibody is an immunoglobulin that binds specifically to a particular epitope of a protein or molecule of interest within a sample. (thp.at)
- Any binding interaction between a primary antibody and the protein of interest is detected using a secondary antibody which will bind to the primary antibody, and thus the protein. (thp.at)
Epithelial1
- It was additionally optimistic for pan - cytokeratin antibody AE1 and AE3 and cytokeratin (CAM) 5.2, which come up from epithelial origin in line with NSCLCs. (inacj.com)
Cytokeratin1
- A big proportion of beforehand recognized NPC circumstances by routine H and E stains had been confirmed to not be so by a minimal IHC antibody pan el of pan - cytokeratin cocktail (AE1/AE3) and leukocyte frequent antigen (CD45). (inacj.com)
Markers1
- Optibodies™ are a range of optimized antibodies for markers which are clinically and diagnostically important. (thp.at)
Clinical5
- 12. The clinical use of a P63/cytokeratin7/18/cytokeratin5/14 antibody cocktail in diagnostic breast pathology. (nih.gov)
- We offer the most comprehensive selection of monoclonal and polyclonal primary antibodies for academic and industrial researchers, but also clinical purposes (CE-IVD). (thp.at)
- In clinical perspective, antibodies must be specific with high affinity towards their epitopes, flexible to use, good LOT consistency and reliable. (thp.at)
- Optibody™ antibodies are carefully validated and fine-tuned with the needs of today's clinical IHC laboratory. (thp.at)
- [ 1 ] These criteria are based on the presence or absence of cancer, the presence of well-characterized paraneoplastic (onconeural) antibodies, and the type of clinical syndrome. (medscape.com)
Minimal1
- Seasonal vaccination induced cross-reactive neuraminidase inhibition and binding antibodies to N9, but minimal cross-reactive antibody-dependent cell-mediated cytotoxicity (ADCC) antibodies to A(H7N9). (cdc.gov)
Clinically2
- Therapeutic antibodies against the α4β1 integrin receptor have been used clinically to attenuate the ability of various immune cells to adhere to endothelium and migrate into target tissues such as the intestines (Crohn's disease) or brain (multiple sclerosis). (nih.gov)
- This data suggests that it is indeed feasible to alter the immune component of AD brain changes using a clinically feasible strategy of delivering a particular subtype of IgG or epitope selective antibodies that target infiltration of the peripheral immune system. (nih.gov)
Secondary1
- Our range of secondary antibodies has been carefully selected to provide optimum quality and flexibility. (thp.at)
Tumors1
- Then again, faulty mismatch restore (dMMR) tumors, primarily positioned in the correct colon, are recognized to have favorable survival and dense native immune infiltration. (inacj.com)
Cocktail1
- 1. Availability of immunocytochemistry using cocktail antibody targeting p63/cytokeratin14 for the differential diagnosis of fibroadenoma and ductal carcinoma in situ in fine needle aspiration cytology of the breast. (nih.gov)
Supplier1
- Find an alternative to any major antibody supplier by using our knowledge in antibody suppliers. (thp.at)
Proteins4
- In addition decreased proteins and mRNA degrees of brain-derived neurotrophic element synaptophysin GKA50 and drebrin had been within SZ weighed against control frontal cortex. (techblessing.com)
- 2007 Proteins concentrations were established with Lowry's proteins reagent (Bio-Rad Hercules CA). Membrane and cytosolic fractions were distinguished using tubulin and cadherin antibodies. (techblessing.com)
- For an antibody to work in chromatin IP, it must be of high titer and it must be very specific, with no detection of non-target proteins. (thp.at)
- Active Motif specializes in manufacturing high-quality antibodies to histones, histone modifications and chromatin proteins and validating them for use in ChIP, as well as ChIP-Seq & ChIP-chip. (thp.at)
Major1
- new fields recognize Inhibitors,research,lifescience,medical the major interactions between genetic make-up and response to diet and dietary changes, both in terms of predisposing to development of obesity, metabolic syndrome, and DM2, and in determining responsiveness to specific dietary changes. (hifpathway.com)
Classification1
- About 50 different lung cancer variants are recognized under the 2004 revision of the World Health Organization ("WHO-2004") histological typing system, the most widely recognized and used lung cancer classification scheme. (wikipedia.org)
Sufferers1
- Nevertheless, whether or not laparoscopic surgical procedure for grossly EGC-mimicking superior gastric most cancers (AGC) sufferers is oncologically secure long-term remains to be controversial.We retrospectively analyzed 472 sufferers with AGC who had been recognized as scientific EGC. (influenza-x.org)
Immune1
Quality1
- Chromatin immunoprecipitation (chromatin IP or ChIP) is an extremely challenging technique, and only antibodies of the highest quality will do. (thp.at)
Highest1
- Vaccine group 1 had the highest antibody responses to the vaccine virus and the 3rd/5th wave drifted viruses. (cdc.gov)
Primary2
- Membranes were incubated over night in tris-buffered-saline remedy containing 5% nonfat dried milk and 0.1% Tween-20 with specific primary antibodies (1:200 dilution) for either NMDA receptors NR-1 NR-2B IL-1R and cadherin (Cell Signaling Beverly MA). (techblessing.com)
- Regardless the field of research you are working in our primary antibodies will support your experiments with well-characterized and consistent performance. (thp.at)
High1
- Although some adults infected with influenza 2009 A(H1N1)pdm09 viruses mounted high hemagglutination inhibition (HAI) antibody response, they still suffered from severe disease, or even death. (cdc.gov)
Services1
- In addition, their Epigenetic Services team offers ChIP Antibody Validation Services in which they will determine if your antibody is suitable for use in ChIP, ChIP-Seq or ChIP-chip. (thp.at)
Similar1
- Notably, the relative levels of cross-reactivity to the drifted viruses as measured by the antibody GMT ratios to the 5th wave viruses were similar across all 4 vaccine groups. (cdc.gov)
Found1
- 8] VP1 antibodies are found in nearly all Merkel cell carcinoma patients, as well as in 42-77% of the general population, demonstrating that virally-induced carcinogenesis is a rare phenomenon. (medscape.com)
Main1
- Nuclear blots were incubated with main antibodies for NF-κBp50 and NF-κBp65 (1:200) (Abcam). (techblessing.com)
Research2
- Avoid delays in your research by using our knowledge where and how to replace Santa Cruz antibodies e.g. with the most popular alternatives from Proteintech ( Replacement list (PDF) ). (thp.at)
- Research frequently necessitates a range of antibodies tailored to the specific needs of each individual project. (thp.at)
Small1
- Moreover, a lot of our antibodies are available in small scale but also and bulk quantities. (thp.at)
Cells1
- Memory space CTL comprehended most of T cells recognized on long-term follow-up of individuals after AHSCT. (monossabios.com)