Antibody quadrivalent vaccine papillomavirus vaccines. Medical search. Frequent questions

Gardasil, Merck & Co. Inc.) for use in males aged 9 through 26 years for prevention of genital warts caused by human papillomavirus (HPV) types 6 and 11. (cdc.gov)
The 9-valent HPV vaccine (Gardasil 9 [9vHPV]) is available in the United States to decrease the risk of certain cancers and precancerous lesions in males and females. (medscape.com)
Gardasil vaccine was fast tracked to licensure by the Food and Drug Administration in 2006. (wfdev.net)
At the National Vaccine Information, we issued our first press release in the summer of 2006 warning parents that Gardasil had not been adequately tested in young girls before government health officials recommended that all 11 and 12 year old girls get three doses of the vaccine. (wfdev.net)
12 Merck only studied Gardasil in fewer than 1200 girls under age 16 and followed them up for about two years before lobbyists tried, unsuccessfully in 2007, to get the vaccine mandated for all sixth grade girls in every state. (wfdev.net)
Even though Gardasil was only tested on about a thousand young girls before licensure in 2006, CDC officials told doctors to give three doses of the vaccine to millions of little girls at a cost averaging $165 per dose. (wfdev.net)
14 Because Merck did not test Gardasil in pre-licensure clinical trials in combination with all other vaccines routinely given to pre-teen and teenage girls, the CDC suggested that safety could be assumed and directed that Gardasil be given simultaneously with other vaccines. (wfdev.net)
But what is Gardasil vaccine supposed to protect our children against? (wfdev.net)
So here's the bottom line: Gardasil vaccine is supposed to prevent a sexually transmitted infection that is naturally cleared from the body within two years by the vast majority of people. (wfdev.net)
Treating Gabrielle's serious Gardasil vaccine injury has cost her family and insurance company tens of thousands of dollars. (wfdev.net)
By mid-2006 the quadrivalent vaccine (Gardasil) was registered by Australia's Therapeutic Goods Administration (TGA) and the bivalent vaccine (Cervarix) was registered in 2007. (ogmagazine.org.au)
A nonavalent vaccine (Gardasil 9) is currently in production which will provide an even greater degree of protection (against 9 HPV types instead of 4: HPV 6/11/16/18/31/33/45/52/58). (nursinginpractice.com)
The aim of the study is to determine di-sorders of immune homeostasis in patients with laryngeal papillomatosis at different periods after complex treatment with the inclusion of the "Gardasil" quadrivalent vaccine in the adjuvant therapy. (uran.ua)
Studies of the immunity state were conducted in 26 patients with laryngeal papillomatosis (LP) before, 2-12 and 13-29 months after complex treatment, consisting of surgical removal of papillomas and anti-relapse therapy, including inhalation of Laferobion, taking a vitamin-mineral complex and a course of vaccination with antiviral "Gardasil" quadrivalent vaccine according to which the second and third injections were administered in 2 and 6 months after the first. (uran.ua)
Complex treatment with the use of the "Gardasil" quadrivalent antiviral vaccine in the postoperative period contributed to the normalization of most immunological reactivity indices that were altered in patients. (uran.ua)
The effectiveness of antirelapse treatment of recurrent laryngeal papillomatosis with the use of the vaccine "Gardasil" in the long term] Zhurn. (uran.ua)
For instance, it is important to note that persistence of antibody responses after a single dose has not been evaluated for Gardasil, the quadrivalent HPV vaccine that is more widely used in the United States and many other countries. (infectioncontroltoday.com)

Although immunization with the human papillomavirus vaccine is recommended for all boys and girls, vaccination rates remain low. (aafp.org)
The Meningococcal Vaccines Work Group of ACIP reviewed available data on immunogenicity in high-risk groups, bactericidal antibody persistence after immunization, current epidemiology, vaccine effectiveness (VE), and cost-effectiveness of different strategies for vaccination of adolescents. (cdc.gov)
In the 2009 National Immunization Survey-Teen, 53.6% of adolescents aged 13 through 17 years had received a dose of meningococcal vaccine ( 3 ). (cdc.gov)
Each year, recommendations for routine use of vaccines in children, adolescents, and adults in the United States are developed by the Advisory Committee on Immunization Practices (ACIP). (cdc.gov)
CDC's National Center for Immunization and Respiratory Diseases (NCIRD) maintains the most current immunization schedules on the Vaccines and Immunizations pages of CDC's website ( http://www.cdc.gov/vaccines/schedules ), including the schedules published in this supplement. (cdc.gov)
Each year, the Advisory Committee on Immunization Practices (ACIP) reviews the current recommended immunization schedules for persons aged 0 through 18 years to ensure that the schedule reflects current recommendations for licensed vaccines. (cdc.gov)
For more information, see Human Papillomavirus (HPV) Advisory Committee on Immunization Practices Vaccine Recommendations and Centers for Disease Control and Prevention (CDC): Human Papillomavirus (HPV) Vaccination Information . (msdmanuals.com)
Overview of Immunization Immunity can be achieved Actively by using antigens (eg, vaccines, toxoids) Passively by using antibodies (eg, immune globulins, antitoxins) A toxoid is a bacterial toxin that has been modified. (msdmanuals.com)
The HPV vaccine is a routine childhood vaccination (see CDC: Child and Adolescent Immunization Schedule by Age ). (msdmanuals.com)
Those who meet the criteria within these schedules can receive the vaccines free-of-charge as part of Manitoba's Immunization Program. (gov.mb.ca)
Catch up schedules for partially immunized individuals must be created in accordance with the current Canadian Immunization Guide and the Vaccines Offered Free-of-Charge ( Eligibility Criteria for Publicly-Funded Vaccines ). (gov.mb.ca)
No live attenuated influenza vaccine (LAIV), known as FluMist, will be offered based on effectiveness recommendations by the Centers for Disease Control and Prevention (CDC) Advisory Committee on Immunization Practices. (blogspot.com)
August is National Immunization Awareness Month, which is sponsored by the National Public Health Information Coalition to encourage people of all ages to make sure they are up to date on the vaccines recommended for them. (blogspot.com)
Use of a 2-dose schedule for human papillomavirus vaccination -- updated recommendations of the Advisory Committee on Immunization Practices. (medscape.org)
Asthma status and waning of measles antibody concentrations after measles immunization. (contemporarypediatrics.com)
Refer to https://www.who.int/teams/immunization-vaccines-and-biologicals/policies/position-papers for most recent version of this table and position papers. (who.int)
Remítase a los Advisory Committee on Immunization Practices Vaccine Recommendations and Guidelines for the most updated vaccine-specific recommendations. (cdc.gov)

Issues reviewed by ACIP included efficacy, immunogenicity, and safety of the HPV4 vaccine in males, epidemiology of HPV and burden of HPV-associated diseases and cancers in males, cost-effectiveness of male vaccination, and programmatic considerations. (cdc.gov)
The efficacy for prevention of HPV 6, 11, 16, or 18-related genital warts among males who received at least 1 vaccine dose and regardless of baseline DNA or serology (intent to treat population), was 67.2%, and the efficacy for prevention of genital warts related to any HPV type was 62.1% ( Table ) ( 5 ). (cdc.gov)
20,000 participants) will determine the efficacy of the HPV L1 VLP vaccine by using prevention of type-related CIN I, genital warts, and CIN II/III as the endpoints. (cdc.gov)
Background: A randomised double-blind placebo-controlled phase II study was done to assess the efficacy of a prophylactic quadrivalent vaccine targeting the human papillomavirus (HPV) types associated with 70% of cervical cancers (types 16 and 18) and with 90% of genital warts (types 6 and 11). (johnshopkins.edu)
In 2002, the first randomised placebo-controlled trial of the efficacy of a VLP-based HPV vaccine showed 100 per cent efficacy in preventing persistent HPV infection in young, previously uninfected women. (ogmagazine.org.au)
A bivalent vaccine with the same efficacy against human papillomavirus types 16 and 18 costing £13-£21 less per dose (depending on the duration of vaccine protection) may be as cost effective as the quadrivalent vaccine although less effective as it does not prevent anogenital warts. (bmj.com)
Thiruvananthapuram: The Rajiv Gandhi Centre for Biotechnology (RGCB) is contributing significantly in determining the efficacy of Cervavax, India's first indigenously developed vaccine for the prevention of cervical cancer, the second-most prevalent cancer among women in the country. (goachronicle.com)
In the development of India's first cervical cancer vaccine, the RGCB at Thiruvananthapuram has facilitated stringent tests in its state of the art laboratory to demonstrate the efficacy of Cervavax with infections as the endpoint. (goachronicle.com)
In case of the qHPV vaccine also, the efficacy is measured by development of antibodies against each type of HPV present in the vaccine," she pointed out. (goachronicle.com)
Thus, one of the measures of vaccine efficacy is also to estimate HPV infection rates in those who are administered the vaccine. (goachronicle.com)
High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up. (vakciny.net)
We report data for the longest efficacy evaluation to date of a prophylactic HPV vaccine. (vakciny.net)
The work of Nelly Mugo (University of Washington), Dr. Anna Wald (Vaccine and Infectious Disease Division) and Dr. Denise Galloway (Human Biology Division), in collaboration with Dr. Dalton Wamalwa (University of Nairobi, Kenya), shows the efficacy of quadrivalent HPV vaccine, in HIV-1 infected girls and boys in Africa. (fredhutch.org)
The assessment of qHPV vaccine efficacy was performed at month 7 and 12. (fredhutch.org)
The authors also sought to assess the effect of HIV-1 infection stage on vaccine efficacy. (fredhutch.org)
Even though HIV-1 related immunosuppression reduces the titer of HPV antibody, the seroconversion rate is so high that the authors do not expect that to be a limitation to the vaccine efficacy. (fredhutch.org)
The performance of on HPV vaccines, H. pylori eradication control group to estimate the efficacy of visual, cytological, and molecular triage for gastric cancer prevention, triage the vaccination schedules. (who.int)
The protective efficacy of these inactivated vaccines was demonstrated in the 1950s. (cdc.gov)

The current HPV vaccine recommendations apply to 9 years old and above through the age of 26 years and adults aged 27-45 years who might be at risk of new HPV infection and benefit from vaccination. (mdpi.com)
Vaccine candidates have been evaluated in animal models of papillomavirus infection. (cdc.gov)
Species-specific VLP vaccines provide protection against infection and disease. (cdc.gov)
The primary endpoint was the combined incidence of infection with HPV 6, 11, 16, or 18, or cervical or external genital disease (ie, persistent HPV infection, HPV detection at the last recorded visit, cervical intraepithelial neoplasia, cervical cancer, or external genital lesions caused by the HPV types in the vaccine). (johnshopkins.edu)
Interpretation: A vaccine targeting HPV types 6, 11, 16, 18 could substantially reduce the acquisition of infection and clinical disease caused by common HPV types. (johnshopkins.edu)
Human papillomavirus ( HPV ) infection must be present for cervical cancer to occur. (medscape.com)
Recognition of the etiologic role of human papillomavirus ( HPV ) infection in cervical cancer has led to the recommendation of adding HPV testing to the screening regimen in women 30-65 years of age (see Workup). (medscape.com)
Infection with Human Papillomavirus (HPV) "is estimated to cause […] 100% of cervical cancer cases," and contributes to the incidence of other cancers affecting both women and men, including anal cancer, oral and oropharyngeal cancers, and cancers of the genitals (WHO, 2008b). (medscinet.com)
Evidence suggests that HPV vaccines prevent HPV infection. (medscape.com)
Human Papillomavirus (HPV) Infection Human papillomavirus (HPV) infects epithelial cells. (msdmanuals.com)
The cause of most cervical cancers is human papillomavirus (HPV) infection. (msdmanuals.com)
Preparations reference Human papillomavirus (HPV) infection is the most common sexually transmitted disease. (msdmanuals.com)
Objective To assess the cost effectiveness of routine vaccination of 12 year old schoolgirls against human papillomavirus infection in the United Kingdom. (bmj.com)
5 Two prophylactic vaccines against human papillomavirus (a bivalent vaccine against types 16 and 18 and a quadrivalent vaccine that also includes types 6 and 11) have been shown to be efficacious in up to five years of follow-up against types 16 and 18 cervical infection and associated disease as well as against anogenital warts. (bmj.com)
At 5 years post enrollment, the combined incidence of HPV 6/11/16/18-related persistent infection or disease was reduced in vaccine-recipients by 96% (two cases vaccine versus 46 placebo). (vakciny.net)
Through 5 years, vaccine-induced anti-HPV geometric mean titres remained at or above those following natural infection. (vakciny.net)
In conclusion, a prophylactic quadrivalent HPV vaccine was effective through 5 years for prevention of persistent infection and disease caused by HPV 6/11/16/18. (vakciny.net)
Understanding the role of naturally acquired (i.e., infection-induced) human papillomavirus (HPV) antibodies against reinfection is important given the high incidence of this sexually transmitted infection. (biomedcentral.com)
We conducted a systematic review and a meta-analysis to (1) strengthen the evidence on the association between HPV antibodies acquired through past infection and subsequent type-specific HPV detection, (2) investigate the potential influence of type-specific HPV antibody levels, and (3) assess differential effects by HIV status. (biomedcentral.com)
However, the extent to which naturally acquired, or infection-induced, antibodies can help prevent HPV reinfection remains poorly understood, especially with respect to the level and the duration of protection. (biomedcentral.com)
In addition, the levels of antibodies in women from the one- and two-dose groups were five to 24 times higher than the levels of antibodies in women who did not receive vaccination, but had prior HPV infection. (infectioncontroltoday.com)
In a polygamous country like Ghana with a high incidence of cervical cancer but no national screening program, the Human Papilloma Virus (HPV) vaccine presents a unique opportunity to reduce the burden of HPV infection and cervical cancer in Ghanaian women. (childsurvival.net)
1 The research also reaffirmed the benefit of the 2-dose varicella vaccine regimen for preventing breakthrough infection, and, in their conclusion, the investigators recommended adherence to the 2-dose varicella vaccine regimen for children with asthma. (contemporarypediatrics.com)
2 Because there were no cases of measles among the prior study's subjects, the question of whether a decline in vaccine-induced adaptive immune function increases the risk of clinical infection could not be explored. (contemporarypediatrics.com)
So, the researchers chose breakthrough varicella infection as a model for their case-control study to determine whether asthma is associated with an increased risk of vaccine-preventable disease. (contemporarypediatrics.com)
These children would likely benefit from the HPV vaccine if the vaccine strategy was efficient despite HIV-1 infection. (fredhutch.org)

Evaluation of immune response to single dose of quadrivalent HPV vaccine at 10-year post-vaccination. (who.int)
Patients received a first dose of quadrivalent HPV vaccine (qHPV, against types 6, 11, 16, 18) at enrollment, a second dose at month 2, a third and last dose at month 6. (fredhutch.org)

Cases of meningococcal disease caused by serogroups C and Y among persons who were vaccinated with meningococcal conjugate vaccine have been reported. (cdc.gov)
In 2010, CDC received 12 reports of serogroup C or Y meningococcal disease among persons who had received a meningococcal conjugate vaccine. (cdc.gov)

More research is needed, particularly regarding the incidence of vaccine-preventable infectious diseases and the safety of vaccination in patients with AIIRD. (bmj.com)
Novavax creates transformational vaccines that help address some of the world's most pressing infectious diseases. (novavax.com)
Novavax has demonstrated its ability to quickly develop viable vaccine candidates for emerging infectious diseases such as COVID-19. (novavax.com)
We are a biotechnology company committed to help address serious infectious diseases globally through the discovery and development of innovative vaccines to patients around the world. (novavax.com)

In addition, a recent case of VITT has been reported after HPV vaccination (recombinant human papillomavirus quadrivalent vaccine) , which uses nonadenoviral virus‐like particle vaccine technology. (informedchoicewa.org)
In total, 552 women (16-23 years) were enrolled in a randomised, placebo-controlled study of a quadrivalent HPV 6/11/16/18 L1 virus-like-particle vaccine with vaccination at months 0, 2, and 6. (vakciny.net)

Different human papillomavirus types share early natural history transitions in immunocompetent women. (who.int)
In particular, human papillomavirus types 16 and 18 are associated with 70% of cervical cancers, 3 whereas 90% of anogenital warts are linked to human papillomavirus types 6 and 11. (bmj.com)
6 7 In addition, the results from clinical trials suggest that both vaccines may offer partial protection against oncogenic human papillomavirus types not in the vaccine. (bmj.com)
Our model considers the impact of vaccination on squamous cell carcinomas, adenocarcinomas, cervical cancers due to high risk human papillomavirus types not in the vaccine, non-cervical cancers, and anogenital warts. (bmj.com)

We are now watching a new revolution: the introduction of the human papillomavirus (HPV) vaccine to the national immunisation schedule is expected to decrease the incidence of invasive cervical cancer further, while simultaneously having an impact on the incidence of high-grade cervical dysplasia, treatment-related sequelae, the incidence of other anogenital cancers, and the suffering associated with genital warts. (ogmagazine.org.au)
Over 200 human papillomavirus (HPV) types, which are members of five genera ( α, β, γ, μ, v ) [ 1 , 2 ], are responsible for approximately 5% of all human cancers and substantial precancerous and benign lesions [ 3 , 4 ]. (oncotarget.com)
Primary prevention of cervical cancer is now possible with the availability of human papillomavirus (HPV) vaccines targeting HPV types 16 and 18, which cause the majority of cervical cancers worldwide, as well as in Africa. (scielo.org.za)
The establishment of and affordable vaccination schemes for investigators in national cancer orga- cancer research networks in LMICs to human papillomavirus (HPV)-related nizations, health services, universities, exchange experiences and enhance the cancers and the evaluation of the impact and other key groups within and outside local capacity is among EDP's priorities. (who.int)

The bivalent and quadrivalent vaccines are approved for females and the quadrivalent vaccine is approved for males. (hiv.gov)

Postlicensure data in females indicate that HPV4 adverse events are similar to adverse events reported following administration of other vaccines to adolescents ( 6 ). (cdc.gov)
4 Because of this, adolescents should be observed for 15 minutes after receiving these vaccines. (aafp.org)
At that time, vaccination was recommended at age 11 or 12 years rather than at age 14 or 15 years because 1) more persons have preventive-care visits at age 11 or 12 years, 2) adding this vaccine at the 11 or 12 year-old visit would strengthen the pre-adolescent vaccination platform, and 3) the vaccine was expected to protect adolescents through the entire period of increased risk. (cdc.gov)
After licensure, additional data on bactericidal antibody persistence, trends in meningococcal disease epidemiology in the United States, and VE have indicated many adolescents might not be protected for more than 5 years. (cdc.gov)
Human papillomavirus vaccination rates in adolescents with cerebral palsy compared to the general population. (childrensmercy.org)
Recommendations for routine use of vaccines in children and adolescents are harmonized to the greatest extent possible with recommendations made by the American Academy of Pediatrics (AAP), the American Academy of Family Physicians (AAFP), and the American College of Obstetrics and Gynecology (ACOG). (cdc.gov)
All adults and adolescents should get the COVID-19 vaccine regardless of their CD4 count or HIV viral load. (hiv.gov)
Most importantly, at 7 months, the seroconversion rate (in this case the proportion of vaccinated patients who developed antibodies against a specific type of the virus) was superior to 93% for all four HPV types targeted by the vaccine, similarly to what was observed for HIV-1 infected US girls, or for HIV-1 negative adolescents from Kenya and Ghana. (fredhutch.org)
This is the first report demonstrating that qHPV vaccine is as efficient in HIV-1 infected adolescents in Africa compared to infected adolescents from developed countries (with higher standards of care) or HIV-1 uninfected adolescents (not immunosuppressed). (fredhutch.org)
The authors point out that the World Health Organization and American Cancer Society recently approved a new schedule for HPV vaccine reducing the vaccination protocol from three to two doses, which may not be as efficient as the three-dose protocol in HIV-infected adolescents. (fredhutch.org)

Antibody responses among adolescent females receiving two or three quadrivalent human papillomavirus vaccine doses at standard and prolonged intervals. (emmes.com)
Human papillomavirus 16L1-58L2 chimeric virus-like particles elicit durable neutralizing antibody responses against a broad-spectrum of human papillomavirus. (oncotarget.com)
In addition, antibody responses to the vaccine are higher before the onset of puberty. (nursinginpractice.com)
Phase 1 data from the Company's Phase 1/2 randomized, observer-blinded, placebo-controlled trial shows that NVX-CoV2373 was generally well-tolerated and elicited robust antibody responses numerically superior to that seen in human convalescent sera. (novavax.com)
Women vaccinated with one dose of a human papillomavirus (HPV) vaccine had antibodies against the viruses that remained stable in their blood for four years, suggesting that a single dose of vaccine may be sufficient to generate long-term immune responses and protection against new HPV infections, and ultimately cervical cancer, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. (infectioncontroltoday.com)
Our findings challenge previous dogma that protein subunit vaccines require multiple doses to generate long-lived responses. (infectioncontroltoday.com)
The researchers also found that while antibody levels among women who received one dose were lower than among those who received the full three doses, the levels appeared stable, suggesting that these are lasting responses. (infectioncontroltoday.com)
The researchers observed the latter findings are consistent with existing information that corticosteroids do not affect humoral or cell-mediated responses to vaccine. (contemporarypediatrics.com)
[9] Recommendations for when vaccines are administered are based on the age-specific disease risks, age-specific risks for complications, and age-specific vaccination responses, as well as possible effects on the passive maternal-fetal immune response. (medscape.com)

Vaccines are available to protect against many of the HPV strains that can cause genital warts and cancer. (msdmanuals.com)

India's Minister of Science and Technology Dr Jitendra Singh on Thursday (September 1), announced the scientific completion of Cervavac, India's first indigenously developed quadrivalent human papillomavirus (qHPV) vaccine for the prevention of cervical cancer . (healthissuesafrica.com)

Thimerosal is currently used only in multidose vials of influenza vaccine, and exposure through vaccines is not associated with adverse neurologic outcomes. (aafp.org)
The virosomal influenza vaccine Invivac: immunogenicity and tolerability compared to an adjuvanted influenza vaccine (Fluad in elderly subjects. (vakciny.net)
The first live, attenuated influenza vaccine was licensed in 2003. (cdc.gov)

The measles, mumps, and rubella vaccine is not associated with autism. (aafp.org)
The measles, mumps, and rubella vaccine does not increase the risk of autism and should be routinely used. (aafp.org)
The study was undertaken as a follow-up to an earlier investigation in which it was found that measles vaccine virus-specific immunoglobulin G levels waned more rapidly in children with asthma or who subsequently developed asthma compared with unaffected controls. (contemporarypediatrics.com)

About 20 percent of the women in the study received fewer than three doses of the vaccine, not by design. (infectioncontroltoday.com)
The researchers looked for the presence of an immune response to the vaccine (measured by antibody levels) in blood samples drawn from 78, 192, and 120 women who received one, two, and three doses of the vaccine, respectively, and compared the results with data from 113 women who did not receive vaccination but had antibodies against the viruses in their blood because they were infected with HPV in the past. (infectioncontroltoday.com)
those with varicella disease or who received ≥2 doses of the vaccine). (medscape.com)

The discovery that human papillomaviruses (HPV) are etiologically linked with cervical cancer has led to efforts to apply this knowledge to improve cervical cancer screening and to potentially prevent cervical cancer through vaccination. (cdc.gov)
Many studies have proven that the use of monovalent, recombinant bivalent, and recombinant quadrivalent vaccines were effective to prevent cervical cancer. (ui.ac.id)
Pradipta, B & Sungkar, S 2007, ' The Use of Human Papilloma Virus Vaccine to Prevent Cervical Cancer ', Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia . (ui.ac.id)
5 However, following on from zur Hausen's crucial studies, research groups all over the world recognised that a vaccine that induced neutralising antibodies to specific 'high-risk' HPV genotypes could theoretically prevent cervical cancer. (ogmagazine.org.au)
Our modeling analysis showed that the vaccination of 12-year-old adolescent girls against cervical cancer with the AS04-adjuvanted human papillomavirus 16/18 vaccine would be a cost-effective strategy to prevent cervical cancer in Hungary. (biomedcentral.com)
Since the introduction of human papillomavirus (HPV) vaccines, both primary and secondary preventive (i.e., screening) measures have been available to prevent cervical cancer. (biomedcentral.com)

Bradley-Ewing A, Lee BR, Doctor JN, Meredith G, Goggin K, Myers A. A pilot intervention combining assessment and feedback with communication training and behavioral nudges to increase HPV vaccine uptake. (childrensmercy.org)
Multilevel Implementation Strategies for Adolescent Human Papillomavirus Vaccine Uptake: A Cluster Randomized Clinical Trial. (mayo.edu)
Socioeconomic disadvantage and human papillomavirus (HPV) vaccination uptake. (mayo.edu)
Determining how long protection from HPV lasts after vaccination could help to bolster public confidence in the vaccine and increase uptake. (myadlm.org)
Implementation of HPV vaccination in a primary school-based programme was successful, with high vaccine uptake and completion rates. (scielo.org.za)

Like other papillomaviruses, BPVs are small non-enveloped viruses with an icosahedral capsid around 50-60 nm in diameter. (wikipedia.org)
Jian Zhou and Ian Frazer's 1991 breakthrough was to use recombinant DNA technology to create virus-like particles (VLPs) of the recombinant HPV-16 L1 capsid protein that mimic the papillomavirus structurally and elicit high titres of neutralising antibodies. (ogmagazine.org.au)
The neutralizing antibodies elicited by human papillomavirus (HPV) major capsid protein L1 virus-like particle (VLP)-based vaccines are largely type-specific. (oncotarget.com)
Recombinant DNA technology is used to prepare HPV vaccines from the major capsid (L1) protein of HPV. (msdmanuals.com)
Most HPV infections clear within 1-2 year by cell-mediated immune response and generation of serum neutralizing antibodies (IgG) against the capsid L1 protein of HPV [ 1 , 8 ]. (biomedcentral.com)

Members of the human herpesvirus (HHV) and human papillomavirus (HPV) families cause the most common primary viral infections of the oral cavity. (medscape.com)
Vaccines or candidate vaccines used to prevent PAPILLOMAVIRUS INFECTIONS. (childrensmercy.org)
Natural History of Incident and Persistent Cutaneous Human Papillomavirus and Human Polyomavirus Infections. (who.int)
Human papillomavirus genotyping using next generation sequencing (NGS) in cervical lesions: Genotypes by histologic grade and their relative proportion in multiple infections. (who.int)
Vaccines mimic natural infections resulting in development of specific antibodies. (goachronicle.com)
Studies have shown the potential protective effect of neutralizing antibodies against subsequent infections when the immune response is initiated by HPV vaccines [ 10 ]. (biomedcentral.com)
Despite the effectiveness of vaccines, disease outbreaks can still occur in our modern day, often as a result of nonimmunization or underimmunization among children and adults, as well as from exposure to infections brought into the country by unvaccinated travelers who visit and return from high-risk or endemic regions. (medscape.com)
Several HPV vaccines have been developed and approved by the Food and Drug Administration and provide an efficient protection against new HPV infections. (fredhutch.org)

Protection was associated with the development of neutralizing antibodies. (cdc.gov)

It contains Novavax ' patented saponin-based Matrix-M™ adjuvant to enhance the immune response and stimulate high levels of neutralizing antibodies. (novavax.com)
NVX‑CoV2373 was created using Novavax' recombinant nanoparticle technology to generate antigen derived from the coronavirus spike (S) protein and contains Novavax' patented saponin-based Matrix-M™ adjuvant to enhance the immune response and stimulate high levels of neutralizing antibodies. (novavax.com)

Family physicians should gather accurate information about the harms and benefits of vaccines to advocate for vaccination and decrease the incidence of vaccine-preventable diseases. (aafp.org)
3 The fourth dose of the diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine is associated with an increased incidence of fever and injection site reactions compared with the first dose (one in four children). (aafp.org)
Meningococcal disease incidence has decreased since 2000, and incidence for serogroups C and Y, which represent the majority of cases of vaccine-preventable meningococcal disease, are at historic lows. (cdc.gov)
Human vaccines are intended to reduce the incidence of UTERINE CERVICAL NEOPLASMS, so they are sometimes considered a type of CANCER VACCINES. (childrensmercy.org)
Human papillomaviruses are responsible for nearly 3000 cases of cervical cancer 1 and more than 100 000 diagnosed cases of anogenital warts 2 in the United Kingdom every year, despite a decrease in the incidence of cervical cancer as a result of regular cytological screening. (bmj.com)
7 8 Both vaccines have the potential to bring a decrease in the incidence of human papillomavirus related disease and are being considered for routine immunisation in many countries. (bmj.com)

Union Science & Technology Minister Dr Jitendra Singh, who announced the scientific completion of the quadrivalent Human Papilloma Virus (qHPV) vaccine in New Delhi last week, said cervical cancer, though largely preventable, accounts for nearly one-fourth of the world's cervical cancer deaths, a statement said here on Sunday. (goachronicle.com)
At month 12, the seropositivity rates were still superior to 90% for type 6, 11 ,16, and 72.5% for type 18, meaning that the qHPV vaccine is highly immunogenic. (fredhutch.org)

CDC guidance for vaccine providers regarding these updated recommendations also is included. (cdc.gov)
Recommendations for routine use of vaccines in adults are reviewed and approved by the American College of Physicians (ACP), AAFP, ACOG, and the American College of Nurse-Midwives. (cdc.gov)
Vaccine-specific recommendations may be outdated. (cdc.gov)

The antibody titres were also increased with AP. (vakciny.net)

2 , 5 Administration of acetaminophen at the time of vaccination or shortly afterward may alleviate some adverse effects, but there may be a decreased antibody response to some vaccine antigens in children who receive antipyretics. (aafp.org)
Immunity to diseases can occur via active immunity (the immune system produces lymphocytes and/or antibodies following exposure to antigens) and passive immunity (immunity is acquired by the transfer of antibodies from a previously immunized person or someone who has recovered from a disease). (medscape.com)

We wanted to evaluate whether two doses, or even one dose, of the HPV 16/18 L1 VLP vaccine [Cervarix] could induce a robust and sustainable response by the immune system,' she adds. (infectioncontroltoday.com)
One of these is Cervarix TM , an AS04-adjuvanted bivalent vaccine against HPV types 16 and 18 produced by GlaxoSmithKline. (biomedcentral.com)
The purpose of this study was to assess the cost-effectiveness of adding vaccination with the AS04-adjuvanted human papillomavirus 16/18 vaccine (Cervarix TM ) at age 12 to the current national cervical screening program. (biomedcentral.com)

The results were sensitive to the price of the vaccine, the discount rate, the screening participation rate and whether herd immunity was taken into account. (biomedcentral.com)

For example, varicella vaccine should be discarded if not used within 30 minutes after reconstitution, whereas MMR vaccine, once reconstituted, must be kept in a dark place at 36°F to 46°F (2°C to 8°C) and should be discarded within 8 hours if not used. (cdc.gov)

SK bioscience shares our sense of urgency to ensure broad and equitable access for our COVID-19 vaccine candidate around the world. (novavax.com)
CEO of SK bioscience said, 'SK's accumulated vaccine R&D and production capability has been spotlighted by the world's most advanced global pharmaceutical companies as well as the global initiatives for the COVID-19 vaccine manufacturing and supply such as CEPI. (novavax.com)
He added, 'We will cooperate with the government supporting its two-track strategy, developing vaccine in Korea and securing COVID-19 vaccine from a global manufacturer in a short period of time. (novavax.com)

11 Those with severe immunosuppression may have a diminished immune response to the vaccine. (hiv.gov)

Caregiver and adolescent factors associated with delayed completion of the three-dose human papillomavirus vaccination series. (childrensmercy.org)
Practice Transformation Program to increase adolescent human papillomavirus, meningococcal, tetanus-diphtheria-pertussis and influenza vaccination. (childrensmercy.org)
The scientists validated their test with blood samples from 49 pre-adolescent girls who received a quadrivalent HPV vaccine and 40 age-matched, unvaccinated girls. (myadlm.org)

Its purpose is to inform clinicians in NYS who provide primary care to individuals with HIV about human papillomavirus (HPV)-related anal disease and assist them in identifying opportunities for prevention, screening, and treatment. (hivguidelines.org)

Therefore a prophylactic vaccine against these four types would substantially reduce HPV-related disease. (cdc.gov)
7 After filing a patent application, Zhou and Frazer licensed their technology in 1995 to a pharmaceutical company to develop a prophylactic vaccine against HPV 16, 18, 6, 11. (ogmagazine.org.au)

SK bioscience, using its cell culture and recombinant protein capability, will initiate the production of the NVX-CoV2373 antigen at its vaccine facility in Andong L-house, South Korea beginning in August 2020 . (novavax.com)
In preclinical trials, NVX‑CoV2373 demonstrated indication of antibodies that block binding of spike protein to receptors targeted by the virus, a critical aspect for effective vaccine protection. (novavax.com)

Phase I trials (300 participants) were performed to establish immunogenicity and tolerability of a range of doses of monovalent HPV L1 vaccines. (cdc.gov)

Self-screening reached the ideal target group, and it is possible to link cervical cancer screening to the cervical cancer vaccine by giving women the opportunity of self-sampling for hrHPV testing. (scielo.org.za)

For 36 months, participants underwent regular gynaecological examinations, cervicovaginal sampling for HPV DNA, testing for serum antibodies to HPV, and Pap testing. (johnshopkins.edu)

Estimates from 8 studies suggested a negative dose-response relationship between HPV antibody level and subsequent detection among females. (biomedcentral.com)
We did not find evidence that naturally acquired HPV antibodies protect against subsequent HPV positivity in males and provide only modest protection among females for HPV-16. (biomedcentral.com)

In the UK the Department of Health has announced a routine human papillomavirus immunisation programme for schoolgirls aged 12 or 13, starting from September 2008, with a two year catch-up programme for girls up to 18. (bmj.com)
Is Routine Human Papillomavirus Vaccination an Option for Ghana? (childsurvival.net)

While vaccines are universally recommended, some children may have contraindications to particular vaccines. (who.int)
Providers are sometimes concerned when they have the same contraindications or precautions as their patients from whom they withhold or defer vaccine. (cdc.gov)
For administration of routinely recommended vaccines, there is no evidence of risk of exposure of vaccine components to the health care provider, so conditions in the provider labeled as contraindications and precautions to a vaccine components are not a reason to withdraw from this function of administering the vaccine to someone else. (cdc.gov)

Antibody titers to 4vHPV types were measured at one and six months post-dose 3 from all participants and post-dose 2 from participants who were on time for dose 3. (emmes.com)
The specificity of the types differs:[citation needed] BPV-1 infects paragenital areas, including penis, teats and udders BPV-2 infects skin, alimentary canal and urinary bladder Xipapillomavirus or epitheliotropic BPVs (formerly known as subgroup B), including types 3, 4 and 6, have a smaller genome of around 7.3 kb and are unique among papillomaviruses in lacking the E6 oncoprotein. (wikipedia.org)
6 Thus, we believe the emerging data on VITT after nonadenoviral vector vaccines highlighted by our case suggests that VITT should remain on the differential diagnosis for thrombotic thrombocytopenic reactions seen after multiple different vaccine types so that an accurate diagnosis can be made and appropriate treatment interventions promptly instituted. (informedchoicewa.org)
It is anticipated that prophylactic HPV vaccines for types 16 and 18 administered to young women before the onset of sexual activity can prevent 70 per cent of cervical cancer cases. (ogmagazine.org.au)
We found that vaccination with the HPV16L1-58L2 cVLP formulated with alum plus monophosphoryl lipid A (Alum-MPL) adjuvant elicited robust neutralizing antibodies in both mice and rabbits against all tested HPV types including HPV16/31/33/35/52/58 (genus α9 ), HPV18/39/45/59/68 (genus α7 ), HPV6/11 (genus α10 ), HPV2/27/57 (genus α4 ), and HPV5 (genus β1 ). (oncotarget.com)
are caused by HPV types not included in the vaccine. (msdmanuals.com)
The test showed that immunoglobulin G antibodies for HPV-16 and -18 (common types of HPV) were much more prevalent among vaccinated girls three years after the third dose of the vaccine compared with unvaccinated girls (63.3% vs. 12.5% for HPV-16). (myadlm.org)

It is estimated that the 9vHPV vaccine can increase prevention of cervical high-grade squamous intraepithelial lesions in up to 90% of cases compared with the quadrivalent HPV vaccine. (medscape.com)
ACIP is chartered as a federal advisory committee to provide expert external advice and guidance to the Director of the Centers for Disease Control and Prevention (CDC) on use of vaccines and related agents for the control of vaccine-preventable diseases in the civilian population of the United States. (cdc.gov)
The Prevention and Implementation two doses for each of the two vaccines. (who.int)

A Learning Collaborative Model to Improve Human Papillomavirus Vaccination Rates in Primary Care. (childrensmercy.org)

Anatomy2

Organisms11

Diseases10

Chemicals and Drugs67

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Psychiatry and Psychology3

Phenomena and Processes7

Anthropology, Education, Sociology and Social Phenomena3

Information Science3

Named Groups1

Health Care11

Geographicals1

Gardasil17

Immunization17

Efficacy18

Infection26

Dose of quadrivalent HPV vaccine2

Conjugate vaccine2

Infectious diseases4

Virus-like particle va2

Human papillomavirus types4

Cancers4

Bivalent and quadrivalent1

Adolescents10

Responses9

Genital1

Indigenously developed1

Influenza vaccine3

Measles3

Doses of the vaccine3

Prevent cervical cancer6

Uptake5

Capsid5

Infections8

Development of neutralizi1

Levels of neutralizi2

Incidence6

QHPV vaccine2

Recommendations3

Titres1

Antigens2

Cervarix3

Immunity1

Varicella1

COVID-19 Vaccine3

Immune response to the vaccine1

Adolescent3

Anal1

Prophylactic vaccine2

Protein2

Monovalent1

Cervical cancer1

Serum antibodies1

Females2

Routine2

Contraindications3

Types7

Prevention3

Vaccination rates1