• Our study shows that an early neurodegenerative process induced by the toxic tau protein can begin just hours after a traumatic brain injury, "Lu said, "We have developed a potent monoclonal antibody that can prevent the onset of widespread neurodegeneration. (hcplive.com)
  • Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Nucleocapsid Protein (NP) Antibody is a chimaeric recombinant Monoclonal Antibody against SARS-CoV-2/COVID-19 NP, containing Mouse variable region and Human IgG1 constant region. (proteomecommons.org)
  • Increasing R&D of monoclonal antibody drugs for novel clinical indications is also expected to boost growth of the market. (pharmiweb.com)
  • 544-MBS212521 Product Name DAXX, Monoclonal Antibody Host Mouse Specificity Mouse anti Human DAXX antibody, clone DAXX-01 recognizes human Death domain-associated protein 6, also known as DAXX, ETS1-associated. (bioscience-explained.org)
  • 639-abx010472 Product Name Brain Natriuretic Peptide (BNP), Monoclonal Antibody Clonality Monoclonal Isotype IgG2b Kappa Host Mouse Species Reactivity Mus musculus (Mouse) Purity/Purification Protein A + Protein G. (bioscience-explained.org)
  • 494-0201-024 Product Overview This product is a recombinant mouse anti-Ebola virus monoclonal antibody. (bioscience-explained.org)
  • 617-CAK71162 Host Mouse Clonality Monoclonal Immunogen Anti-His monoclonal antibody is produced by immunizing. (bioscience-explained.org)
  • We have also found that smg p25A is mainly detected inneural tissues by use of its specific monoclonal antibody, and that the levels of smg p25A mRNA increase in PC12 cells after their differentiation into neuron-like cells. (nii.ac.jp)
  • Since the first monoclonal antibody was clinically approved 35 years ago, there have been considerable advances in antibody technology . (bvsalud.org)
  • Nivolumab is a human monoclonal antibody. (janusinfo.se)
  • Anti-citrullinated protein antibodies (ACPAs) are autoantibodies (antibodies to an individual's own proteins) that are directed against peptides and proteins that are citrullinated. (wikipedia.org)
  • Clinically, cyclic citrullinated peptides (CCP) are frequently used to detect these antibodies in patient serum or plasma (then referred to as anti-citrullinated peptide antibodies). (wikipedia.org)
  • The use of peptides for the generation of antibodies against specific peptides has become an essential tool in proteomic research. (gbiosciences.com)
  • A crucial step in using peptides as antigens is their coupling to carrier proteins. (gbiosciences.com)
  • The carrier proteins, once coupled to the peptides, provide these additional motifs and generate a strong antibody response. (gbiosciences.com)
  • The carrier proteins are coupled to haptens, including peptides and small proteins, with the use of protein cross-linkers. (gbiosciences.com)
  • ActiveHOOK™ carrier proteins have been pre-activated with the heterobifunctional protein cross linker sulfoSMCC and therefore are ready for the addition of cysteine containing peptides or proteins for a simple one step reaction. (gbiosciences.com)
  • The ActiveHOOK™ BSA rapidly couples to free sulfhydryl groups on peptides and proteins. (gbiosciences.com)
  • Keyhole limpet hemocyanin is a widely used carrier protein due to its large molecular mass (4.5x105-1.3x107Da aggregates) and large number of primary amines that can react with cross-linkers for the coupling of peptides. (gbiosciences.com)
  • Antibodies to citrullinated (CitP) and norleucine-containing (NorP) peptides were detected in the sputum of patients with RA and control participants, as well as in the serum of RA patients, using an enzyme-linked immunosorbent test. (physiciansweekly.com)
  • These synthetic peptides corresponded to different regions of the vimentin gene product, but are shared between the human (NP_003371, NCBI) and mouse (NP_035831, NCBI) protein sequences. (antibodiesinc.com)
  • The use of amino acids, proteins and peptides is not expected to have any environmental impact. (janusinfo.se)
  • According to the European Medicines Agency guideline on environmental risk assessments for pharmaceuticals (EMA/CHMP/SWP/4447/00), vitamins, electrolytes, amino acids, peptides, proteins, carbohydrates, lipids proteins, vaccines and herbal medicinal products are exempted because they are unlikely to result in significant risk to the environment. (janusinfo.se)
  • The presence of autoantibodies against citrullinated proteins in rheumatoid arthritis patients was first described in the mid-1970s when the biochemical basis of antibody reactivity against keratin and filaggrin was investigated. (wikipedia.org)
  • We sought to determine whether immune reactivity occurs between anti-SARS-CoV-2 protein antibodies and human tissue antigens, and whether molecular mimicry between COVID-19 viral proteins and human tissues could be the cause. (frontiersin.org)
  • This extensive immune cross-reactivity between SARS-CoV-2 antibodies and different antigen groups may play a role in the multi-system disease process of COVID-19, influence the severity of the disease, precipitate the onset of autoimmunity in susceptible subgroups, and potentially exacerbate autoimmunity in subjects that have pre-existing autoimmune diseases. (frontiersin.org)
  • Cross-reactivity occurs when amino acid sequence homology exists between a pathogen and self-tissue proteins ( 1 ). (frontiersin.org)
  • In this mechanism, antibodies formed against SARS-CoV-2 would also bind to human tissue proteins leading to autoimmune reactivity. (frontiersin.org)
  • 513-CABT-B1265 Species reactivity Human Host/Isotype Mouse / IgG1 To classify Monoclonal Type Antibody Clone OTI7B10 Immunogen Full length human PDCD1LG2 recombinant protein produced in HEK293T cell. (bioscience-explained.org)
  • Randox Biosciences is a world-leading primary manufacturer of high quality monoclonal and polyclonal antibodies, antibody fragments and human recombinant proteins. (randox.com)
  • Randox Biosciences offers an extensive portfolio of over 900 products for a multitude of R&D applications including more than 500 monoclonal and polyclonal antibodies and over 140 human recombinant proteins as well as antibody fragments, buffers & diluents and plasma. (randox.com)
  • Key components of our custom service are our range of monoclonal antibodies as well as our recombinant antibody fragments (sdAbs, scFvs, fAbs). (randox.com)
  • A potential solution to these problems is to select intracellular antibody fragments to block PPIs, use these antibody fragments for target validation in disease models and finally derive small molecules overlapping the antibody-binding site. (nih.gov)
  • Our results may aid RAS-dependent cancer drug development and demonstrate a general concept for developing small compounds to replace intracellular antibody fragments, enabling rational drug development to target validated PPIs. (nih.gov)
  • Besides classical monoclonal antibodies and antibody fragments, new antibody formats can broaden the therapeutic space of new biological entities. (tu-darmstadt.de)
  • Among these are molecules such as bispecific antibodies (bsAbs) and immunoligands, as wells as other antibody fragments and derivates - such as camelid single domain antibody Fc-fusions. (tu-darmstadt.de)
  • Chondrichthyes such as sharks and rays provide a source of single-domain antibody fragments known as variable new antigen receptors (VNARs), which have been exploited as molecular targeting agents. (bvsalud.org)
  • Moreover, pharmaceutical recombinant protein is increasingly adopted for the treatment of diseases such as cancer, diabetes, anemia, and hepatitis. (medgadget.com)
  • Medicinal and industrial usage of recombinant protein in drug manufacturing is rising, coupled with increasing demand for various protein expression systems and other related high-tech systems, which are expected to drive the market growth. (medgadget.com)
  • Recombinant therapeutic antibodies and proteins market is expected to witness significant growth over the forecast period, attributed to rising advancements in the development of recombinant therapeutic drugs. (medgadget.com)
  • Increasing focus on recombinant therapeutics for drug development is expected to drive growth of the recombinant therapeutic antibodies and proteins market over the forecast period. (medgadget.com)
  • Furthermore, recombinant therapeutic antibodies and proteins market is expected to exhibit high growth, attributed to increasing adoption of protein-engineering technologies and government support for its development. (medgadget.com)
  • Schlossarek, S., Mearini, G. and Carrier, L. (2011) Cardiac myosin-binding protein c in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities. (scirp.org)
  • Recombinant Therapeutic Antibodies and Proteins Market Sh. (pharmiweb.com)
  • Therapeutic proteins such as non-covalent binders are developed in labs and find application in the pharmaceutical sector. (pharmiweb.com)
  • Therapeutic proteins are used in the treatment of chronic and rare disorders. (pharmiweb.com)
  • These proteins support a targeted therapeutic process and reimburse the lack of a pivotal protein in order to offer a tailored method of therapy. (pharmiweb.com)
  • For instance, according to the National Center for Biotechnology Information (NCBI) data of 2017, the U.S. Food and Drug Administration (FDA) approved over 140 recombinant therapeutic proteins for human use and several hundred are currently in development. (pharmiweb.com)
  • The global recombinant therapeutic antibodies and proteins market size was valued at US$ 91.2 billion in 2017, and is expected to witness a robust CAGR of 12.2% over the forecast period (2018 - 2026). (pharmiweb.com)
  • Use of several recombinant methodologies has enhanced the half-life, functionality, and targeting ability of new therapeutic protein drugs. (pharmiweb.com)
  • Some of the widely adopted recombinant therapeutic products are monoclonal antibodies that can be produced using various platform-based approaches. (pharmiweb.com)
  • Major governments around the world are focused on supporting R&D in recombinant therapeutic antibodies and proteins, which is expected to boost growth of the market. (pharmiweb.com)
  • High prevalence of rare disorders is also contributing to growth of the recombinant therapeutic antibodies and proteins market. (pharmiweb.com)
  • These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans. (antibodiesinc.com)
  • It may also be possible to use this approach to detect proteins associated with cancer or heart disease, says Michael Strano, the Carbon P. Dubbs Professor in Chemical Engineering at MIT. (mit.edu)
  • The new paper represents their first attempt to identify corona phases that can detect proteins, which are larger, more complex, and more fragile than the molecules identified by their previous sensors. (mit.edu)
  • The good news is that the researchers have also developed an antibody to that protein, which they said can detect and destroy it thus stopping the neurodegenerative process-at least in mouse models. (hcplive.com)
  • The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. (genetex.com)
  • 592-781553 Antibodies that detect p16INK4a can be used in several scientific applications, including Western Blot, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunohistochemistry and ELISA. (bioscience-explained.org)
  • 544-MBS850641 Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal C3 Suitable for: IHC-P, WB Reacts with: Mouse, Rat, Human Antibodies that detect. (bioscience-explained.org)
  • 26-5993-100 Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal mCherry Suitable for: IP, WB Reacts with: Species independent Antibodies that detect. (bioscience-explained.org)
  • 498-BSM-52750R COX4 Antibodies Antibodies that detect COX4 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Flow Cytometry and. (bioscience-explained.org)
  • Western Blot: Tight Junction Protein 2 Antibody [NBP1-86850] - Primary mouse lung endothelial cells treated with or without control IgG was blotted with the anti-TJP-2 antibody. (novusbio.com)
  • Primary Antibody diluted 1:1000. (novusbio.com)
  • Immunocytochemistry/ Immunofluorescence: Tight Junction Protein 2 Antibody [NBP1-86850] - Staining in primary mouse lung endothelial cells. (novusbio.com)
  • Evidence is presented that 19S β 2 M macroglobulin antibodies as well as 7S gamma globulin antibodies are formed during the course of primary malarial infections in human volunteers. (ajtmh.org)
  • We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells. (amsbio.com)
  • by Abnova - A powerful platform for protein-protein interaction and protein phosphorylation studies in situ is created by combining Abnovas dual recognition, primary antibody pair with proximity ligation assay from Olink Bioscience. (dnatube.com)
  • Conjugated primary antibodies with 490 nm, 550 nm, 594 nm, and 650 nm fluorophores! (antibodiesinc.com)
  • Cytokines are small proteins that are secreted by immune cells and help ensure a rapid response to restrict a virus. (freerepublic.com)
  • We applied both human monoclonal anti-SARS-Cov-2 antibodies (spike protein, nucleoprotein) and rabbit polyclonal anti-SARS-Cov-2 antibodies (envelope protein, membrane protein) to 55 different tissue antigens. (frontiersin.org)
  • Elabscience Category Type: Polyclonal Synonyms: 2019-nCoV E protein, 2019-nCoV sM protein, Envelope small membrane protein. (proteomecommons.org)
  • BioServUKDescription:SARS Coronavirus Membrane Protein (Matrix) (E.coli) 500ugStorage conditions: -80˚C. Avoid repeated. (proteomecommons.org)
  • Synthetic peptide corresponding to aa 644-659 (CN 644 YEFKKITED TVEFGS 659 ) of C-terminal rat PMP70 (peroxisomal membrane protein 70). (enzolifesciences.com)
  • Peroxisomal membrane protein 70 (PMP70) is an abundant, integral membrane protein of the peroxisome. (enzolifesciences.com)
  • In the present study, five proteins highly expressed in pancreatic islets with no expression in the surrounding exocrine glandular cells of pancreas, and one protein with the opposite expression pattern, were identified by searches in the Human Protein Atlas (www.proteinatlas.org). (nih.gov)
  • The proteins were analyzed immunohistochemically on a specially designed tissue microarray, containing isolated human islets and pancreatic tissues with different characteristics, and compared to the expression of previously known markers of endocrine and exocrine pancreatic cells. (nih.gov)
  • Our custom development service, which encompasses antibodies and human recombinant proteins has achieved tremendous success within the biopharmaceutical and diagnostic industries. (randox.com)
  • On their own, none of the polymers had any affinity for the 14 proteins tested, all taken from human blood. (mit.edu)
  • Western Blot: Tight Junction Protein 2 Antibody [NBP1-86850] - Analysis in human cell lines A-431 and SK-MEL-30 using anti-TJP2 antibody. (novusbio.com)
  • Immunohistochemistry-Paraffin: Tight Junction Protein 2 Antibody [NBP1-86850] - Staining of human pancreas shows weak cytoplasmic psotivity in exocrine glandular cells. (novusbio.com)
  • Immunocytochemistry/ Immunofluorescence: Tight Junction Protein 2 Antibody [NBP1-86850] - Staining of human cell line U-2 OS shows positivity in plasma membrane, cytoplasm and cell junctions. (novusbio.com)
  • Immunohistochemistry-Paraffin: Tight Junction Protein 2 Antibody [NBP1-86850] - Staining of human testis shows strong membranous and cytoplasmic positivity in cells in seminiferous ducts. (novusbio.com)
  • Immunohistochemistry-Paraffin: Tight Junction Protein 2 Antibody [NBP1-86850] - Staining of human colon shows moderate cytoplasmic and membranous positivity in glandular cells. (novusbio.com)
  • Protein A package is recommended for the purification of human antibodies. (fishersci.com)
  • Their next goal is to "humanize" the antibody so it can be used for early detection and treatment of neurodegeneration in the human brain. (hcplive.com)
  • Based on analysis of non-fractionated, directly labeled, whole human serum proteomes we have identified a protein signature based on 19 non-redundant analytes, that discriminates between cancer patients and healthy subjects. (lu.se)
  • We also did selective epitope mapping using BLAST and showed similarities and homology between spike, nucleoprotein, and many other SARS-CoV-2 proteins with the human tissue antigens mitochondria M2, F-actin and TPO. (frontiersin.org)
  • Very recently, human monoclonal antibodies were approved for use on patients with COVID-19. (frontiersin.org)
  • The human monoclonal antibodies used in this study are almost identical with these approved antibodies. (frontiersin.org)
  • Dual recognition enzyme-linked immunosorbent assay (ELISA) capable of detecting semi-quantitatively total SARS-CoV-2 virus N-protein-specific antibodies (IgG, IgM and IgA) in a single human serum or. (proteomecommons.org)
  • This chimeric human antibody was made using the variable domain sequences of the original VHH format, for improved compatibility with existing reagents, assays and techniques. (prosci-inc.com)
  • Human GFAP is a 49,749 dalton protein (432 amino acids) expressed in astrocytes. (neuromics.com)
  • Here we report two monoclonal antibodies (mAbs) cloned from memory B cells of patients recently recovered from COVID-19, and both mAbs specifically bind to the spike (S) protein of SARS-CoV-2, block the binding of receptor binding domain (RBD) of SARS-CoV-2 to human angiotensin converting enzyme 2 (hACE2), and effectively neutralize S protein-pseudotyped virus infection. (medrxiv.org)
  • These technologies include the use of human naïve, semi-synthetic or synthetic antibody diversities (to avoid the immunogenicity issue) in combination with cellular or non-cellular in vitro selection systems for the presentation and isolation of antibodies, such as Phage or Yeast Display. (tu-darmstadt.de)
  • Three different antipeptide antibodies were generated in chickens against sequences shared between the mouse (NP_035831) and human (NP_003371) gene products. (antibodiesinc.com)
  • These antibodies have been validated with human, mouse and rat tissues. (antibodiesinc.com)
  • Human Vimentin is a 53,521 dalton protein (466 amino acids) expressed in many cell types of mesodermal origin and is one of the intermediate filament types that form the cytoskeleton. (antibodiesinc.com)
  • Schematic representation of the partial purification of misfolded, disease-associated prion protein from chronic wasting disease (CWD)-affected deer brain specimens and its continued ability to seed the conversion of human prion protein (PrP) during protein misfolding cyclic amplification (PMCA) reactions. (cdc.gov)
  • Another is the ability of M protein to bind a human protein called fibronectin (Fn). (lu.se)
  • ECSA Scientific Day 2023 (23 November 2023): Antibodies against high-risk human papillomavirus proteins as markers for noncervical HPV-related cancers in a black South African population, according to HIV status. (who.int)
  • Human papillomavirus (HPV) proteins may elicit antibody responses in the process towards HPV-related malignancy. (who.int)
  • The Food and Drug Administration (FDA) has recommended that all donated blood be screened for antibodies to human immunodeficiency virus type 2 (HIV-2) beginning no later than June 1, 1992. (cdc.gov)
  • Efforts to prevent transmission of human immunodeficiency virus type 1 (HIV-1), particularly through the blood supply, led to the rapid development in 1985 of diagnostic tests for HIV-1 antibodies. (cdc.gov)
  • On April 25, 1990, the Food and Drug Administration (FDA) licensed an enzyme immunoassay (EIA) test kit for detection of antibodies to HIV-2 in human serum or plasma. (cdc.gov)
  • The RA associated citrullinome has been reported to include targets from synovial fluid and tissue that range from proteases, receptors, and carrier proteins. (wikipedia.org)
  • We found that SARS-CoV-2 antibodies had reactions with 28 out of 55 tissue antigens, representing a diversity of tissue groups that included barrier proteins, gastrointestinal, thyroid and neural tissues, and more. (frontiersin.org)
  • To characterize the family of proteins, a panel of subtype-selective antibodies was generated against recombinant muscarinic receptor proteins and shown to bind specifically to each of the cloned receptors. (jneurosci.org)
  • If their shapes are significantly altered, the proteins may be seen as antigens by the immune system, thereby generating an immune response. (wikipedia.org)
  • Subsequent studies demonstrated that autoantibodies from RA patients react with a series of different citrullinated antigens, including fibrinogen, deiminated Epstein-Barr Virus Nuclear Antigen 1 and vimentin, which is a member of the intermediate filament family of proteins. (wikipedia.org)
  • Cross-reaction was found between S. equina antigens and antibodies in the sera of Wuchereria bancrofti -infected patients, with the highest levels observed between sera of chronic infected patients and Setaria spp. (who.int)
  • Antiicitrullinated protein/peptide antibodies could be found in RA patients' sputum and were linked to their presence in the serum. (physiciansweekly.com)
  • Finally, equal volumes of each of the three affinity-purified anti-peptide antibodies were mixed, and the preparation was filtersterilized. (antibodiesinc.com)
  • A 2006 clinical study showed that anti viral citrullinated peptide (VCP) antibodies of the IgG and IgA isotypes represent a discriminating specific marker of rheumatoid arthritis from other chronic arthritides and disease controls, suggesting an independent production of each isotype. (wikipedia.org)
  • During inflammation, arginine amino acid residues can be enzymatically converted into citrulline residues in proteins such as vimentin, by a process called citrullination. (wikipedia.org)
  • Proteins are made up of hundreds or thousands of smaller units called amino acids, which are attached to one another in long chains. (medlineplus.gov)
  • There are 20 different types of amino acids that can be combined to make a protein. (medlineplus.gov)
  • As nivolumab is a protein composed of natural amino acids, proteins are expected to biodegrade in the environment and not pose a significant risk. (janusinfo.se)
  • 247-OAEF00516 Mouse monoclonal Yellow Fever Virus NS1 Suitable for: ELISA Isotype: IgG1 Specificity This antibody is specific for the NS1 protein of Yellow Fever virus, and does not cross-react with NS1 from other. (bioscience-explained.org)
  • 270-11-302-C100 Mouse monoclonal [1696] to HIV protease Suitable for: Dot blot Isotype: IgG1 Specificity The antibody recognizes free N-terminus of mature HIV protease (HIV-1 and HIV-2). (bioscience-explained.org)
  • 372-CA006-100 Target Protein Cytomegalovirus ICP36 DNA Binding Protein Target Protein Also Known As pUL44, MDBP, pp52, DB52 Clone Designation 10D8 Species/Isotype Mouse IgG1(k) Purity Affinity. (bioscience-explained.org)
  • Green Fluorescence Protein (affinity purified) antibody, 100 ug - 1 kit is backordered and will ship as soon as it is back in stock. (dnamethsoc.com)
  • Antibodies were affinity-purified and mixed in equal concentrations. (antibodiesinc.com)
  • We believe the answer is probable, since some of the systemic disease clinical manifestations of COVID-19 cannot be explained solely by the binding of SARS-CoV-2 spike proteins with cell membranes of tissues that exhibit angiotensin-converting enzyme 2 (ACE2). (frontiersin.org)
  • 4F10 was against the Epstein-Barr virus (EBV) Zta protein and 311 H specifically recognized EBV DNase enzyme. (karger.com)
  • This revolutionary combination enables unprecedented specificity and sensitivity of protein detection and quantification for high performance immunofluorescence and immunohistochemistry applications. (dnatube.com)
  • Each of the three antibodies were analyzed by immunohistochemistry (at a dilution of 1:2000) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution, Aves Labs Cat. (antibodiesinc.com)
  • We have found that the C-terminal systeine residues of smg p21B, rhoA p21, and smg p25A are geranylgeranylated, and that these prenylation are essential for each small G protein to bind to membranes. (nii.ac.jp)
  • Our data showed that these pathogenic antibodies, through a mechanism of Antibody Dependent Auto-Attack (ADAA), target and bind to host vulnerable cells or tissues such as damaged lung epithelium cells, initiate a self-attack immune response, and lead to serious conditions including ARDS, cytokine release, and death. (researchsquare.com)
  • Furthermore, the pathogenic antibodies can bind to unmatured fetal tissues and cause abortions, postpartum labors, still births, and neonatal deaths of pregnant mice. (researchsquare.com)
  • Antibodies bind to specific foreign particles, such as viruses and bacteria, to help protect the body. (medlineplus.gov)
  • These proteins bind and carry atoms and small molecules within cells and throughout the body. (medlineplus.gov)
  • One of these mechanisms involves the production of the M protein, which, amongst other things, acts as an anti-phagocytic factor and can bind host proteins. (lu.se)
  • Using carbon nanotubes, MIT chemical engineers have devised a new method for detecting proteins, including fibrinogen, one of the coagulation factors critical to the blood-clotting cascade. (mit.edu)
  • Messenger proteins, such as some types of hormones, transmit signals to coordinate biological processes between different cells, tissues, and organs. (medlineplus.gov)
  • The increase in this serum globulin coincides closely with the appearance of antibodies to malaria as detected by fluorescent antibody studies. (ajtmh.org)
  • Phycobiliproteins are fluorescent proteins derived from cyanobacteria and eukaryotic algae. (dojindo.com)
  • Title : An evaluation of the Kolmer Reiter protein and fluorescent treponemal antibody tests Personal Author(s) : Tucker, Cecil B.;Cameron, George M.;Buchanan, Rufus L.;Dillon, Ann;Grayson, John H. (cdc.gov)
  • Dengue virus Envelope protein antibody detects Dengue virus Envelope protein protein at cytoplasm by immunohistochemical analysis. (genetex.com)
  • If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase. (thermofisher.com)
  • This study, using a virus-free mouse model, explores the pathogenic roles of certain antibodies specific to the spike proteins of highly pathogenic coronaviruses such as the COVID-19 and the SARS-CoV viruses. (researchsquare.com)
  • The SARS-CoV-2 Nucleoprotein (also known as Nucleocapsid Protein or N Protein) is a protein that binds to the RNA in the viral particle. (proteomecommons.org)
  • Here, we have used a recombinant scFv antibody microarray in an attempt to classify sera derived from pancreatic adenocarcinoma patients vs. healthy subjects. (lu.se)
  • Specific Fab antibodies against CEACAM6, EGFR and hCG were isolated from the immune repertoires of transgenic rats and wild type chickens (Yeast Display), and EGFR-specific scFv and VHH antibodies were isolated from the immune repertoires of chickens and camelids (Phage Display). (tu-darmstadt.de)
  • Ribosome-inactivating protein karasurin-C Antibody, FITC conjugated is Available at Gentaur Genprice with the fastest delivery. (joplink.net)
  • CusabioRibosome-inactivating protein karasurin-C Antibody, HRP conjugated is Available at Gentaur Genprice. (joplink.net)
  • CusabioRibosome-inactivating protein bryodin I Antibody, FITC conjugated is Available at Gentaur Genprice. (joplink.net)
  • Using mAb 4F10 as a probe, the Zta protein could be detected as a 36-kD molecule in L5 cells and as a 38-kD molecule in B95-8 cells, reflecting the fact reported by other laboratories, using rabbit polyclonal antisera, that the Zta protein was variously modified in different host cells. (karger.com)
  • However, when HIV testing is indicated, tests for antibodies to both HIV-1 and HIV-2 should be obtained if epidemiologic risk factors for HIV-2 infection are present, if clinical evidence exists for HIV disease in the absence of a positive test for antibodies to HIV-1, or if HIV-1 Western blot results exhibit the unusual indeterminate pattern of gag plus pol bands in the absence of env bands. (cdc.gov)
  • A positive result by HIV-1 Western blot confirms the presence of antibodies to HIV, and testing for HIV-2 is recommended only if HIV-2 risk factors are present. (cdc.gov)
  • Here we describe 5 candidate proteins for further investigation of their physiological role and potential involvement in the pathogenesis of diabetes. (nih.gov)
  • Protein phosphorylation plays an important role in physiological processes, such as muscle contraction. (scirp.org)
  • This protein plays a key role in a number of physiological processes and can be used by GAS to evade the immune system. (lu.se)
  • This gene encodes the major vault protein which is a lung resistance-related protein. (thermofisher.com)
  • Publications] Kaibuchi,K.: 'Molecular cloning and characterization of the stimulatory GDP/GTP exchange protein(GDS)for smg p21s,ras p21ーlike small GTPーbinding proteins. (nii.ac.jp)
  • Small volumes of Anti-carbamylated Protein Antibody elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. (caslab.com)
  • In comparison to the traditional generation of antibody libraries, GGC could be validated with regards to gene repertoire distribution, the overall size of libraries as well as to the biophysical characteristics of isolated antibodies. (tu-darmstadt.de)
  • For instance, protein conjugation and derivatization methods, including albumin-fusion15, PEGylation and Fc-fusion are in trend for increasing the circulating half-life of a therapy. (pharmiweb.com)
  • Recognizes native and denatured forms of purified GST or GST fusion proteins. (bioscience-explained.org)
  • Design and Construction of Antibody Fusion Proteins Incorporating Variable New Antigen Receptor (VNAR) Domains. (bvsalud.org)
  • A major breakthrough has been the design of multispecific antibodies and antibody fusion proteins , which introduce the possibility of recognizing two or more targets with a single molecule. (bvsalud.org)
  • Here, we describe methods to engineer antibody fusion proteins that incorporate VNARs. (bvsalud.org)
  • Fusion proteins are compounds that are produced in the laboratory and combine or "fuse" two different proteins with desirable immune-modifying and disease-fighting traits to form a single drug. (msdmanuals.com)
  • When given to a person, the newly created fusion protein can be used to modify the natural immune response and treat many diseases. (msdmanuals.com)
  • An example of a fusion protein is the drug etanercept , which fuses a cytokine receptor with an antibody. (msdmanuals.com)
  • This antibody was raised against Dengue virus 2 Envelope protein, which may cross react with Envelope protein of Dengue virus 3 but does not recignize with Envelope protein of JEV. (genetex.com)
  • Green: Dengue virus Envelope protein stained by Dengue virus Envelope protein antibody (GTX127277) diluted at 1:1000. (genetex.com)
  • Non-infected (-) and infected (+) BHK-21 whole cell extracts (5 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Dengue virus Envelope protein antibody (GTX127277) diluted at 1:25000. (genetex.com)
  • 182 : 104907 Development of antibody-based assays for high throughput discovery and mechanistic study of antiviral agents against yellow fever virus. (genetex.com)