• The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. (nih.gov)
  • TSG101 antibody [4A10] detects TSG101 protein at cytoplasm by immunohistochemical analysis. (genetex.com)
  • This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. (nih.gov)
  • The protein may play a role in cell growth and differentiation and act as a negative growth regulator. (genetex.com)