AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
beta-LactamasesCephaloridineAntibodiesMicrobial Sensitivity TestsAntibody SpecificityAnti-Bacterial AgentsAntibodies, ViralAntibodies, MonoclonalAntibodies, BacterialAntibody FormationAntibodies, NeutralizingAntibody AffinityFluorescent Antibody TechniqueInterleukin-1betaAntibodies, Anti-IdiotypicBinding Sites, AntibodyEpitopesHIV AntibodiesAntibodies, NeoplasmAntibodies, Protozoanbeta 2-MicroglobulinAntibodies, AntinuclearCross ReactionsMolecular Sequence DataAutoantibodiesImmunoglobulin MIntegrin beta3Antibodies, FungalReceptors, Adrenergic, betaNeutralization TestsMice, Inbred BALB CAmino Acid SequenceCell LineAntigen-Antibody ReactionsAntibodies, BispecificAntibodies, BlockingCells, CulturedSingle-Chain AntibodiesImmunoglobulin GRecombinant ProteinsAntigen-Antibody ComplexImmunoglobulin Fab FragmentsRabbitsbeta 2-Glycoprotein ITransforming Growth Factor betaAntibodies, HeterophileAntibodies, CatalyticBase SequenceFluorescent Antibody Technique, IndirectBlotting, WesternImmune SeraImmunoglobulin AHybridomasAntibodies, AntiphospholipidAntibodies, Monoclonal, HumanizedEpitope MappingImmunohistochemistryEnzyme-Linked Immunosorbent AssayImmunizationImmunoenzyme TechniquesAntigens, SurfaceIntegrin alpha5beta1AntigensRNA, MessengerMolecular WeightIntegrin beta4Electrophoresis, Polyacrylamide GelImmunoblottingIntegrin beta ChainsIntegrinsAntigens, BacterialIntegrin alpha6beta4Mice, Inbred C57BLIntegrin alpha4beta1
Monoclonal AntibodiesMetallo-beta-lactamasesInhibitorsBiotinBispecificExtended-spectrumResistanceInhibitorCD20FragmentDetectionBacteriaActivatesAntigenGeneViralBlockersDrugsDiagnosticsResponsesSubunitPatientsProteinsCellularClinicalHttpsPeptideHumanCellsProductionCellSmallVirusPresenceSimilarProperties
Monoclonal Antibodies2
  • Identification and Characterization of Functional Human Monoclonal Antibodies to Plasmodium vivax Duffy-Binding Protein. (tropmedres.ac)
  • Drug discovery efforts targeting this receptor and other pathway components have centred on monoclonal antibodies and small molecule inhibitors. (biomedcentral.com)
Metallo-beta-lactamases1
  • Dr Garau is author and co-author of more than fifty publications in high-quality journals, including JACS, PNAS, Nature Neuroscience and Structure (Cell), a book chapter (X-ray Structures and Mechanisms of Metallo-Beta-Lactamases), and received several research highlights with international collaborators. (iit.it)
Inhibitors2
  • Clavulanic acid is in a class of medications called beta-lactamase inhibitors. (baranbaspar.com)
  • After cellular stimulation with EGF and analysis at the level of AP-1 activation using a β-lactamase reporter gene, a 10-12 fold shift or 2.5-3 fold shift toward greater potency in the IC 50 was observed for EGFR and MEK-1 inhibitors, respectively, in the presence of RNAi targeting EGFR. (biomedcentral.com)
Biotin1
  • CusabioHAGH Antibody, Biotin conjugated is Available at Gentaur Genprice with the fastest delivery.Online Order Payment is possible or send. (joplink.net)
Bispecific1
  • Located in South San Francisco, Sutro Biopharma focuses on next-generation cancer and autoimmune therapeutics with the development of antibody conjugates, bispecific antibodies and cytokine derivatives. (biospace.com)
Extended-spectrum3
  • Ashayeri-Panah M, Feizabadi MM, Eftekhar F (2014) Correlation of multi-drug resistance, integron and blaESBL gene carriage with genetic fingerprints of extended-spectrum β-lactamase producing Klebsiella pneumoniae . (springer.com)
  • Prevalence of extended spectrum Beta-lactamase and AmpC beta lactamase in gram negative bacilli isolated from various clinical samples in a tertiary care hospital. (edu.in)
  • OBJECTIVES: Escherichia coli producing CTX-M-type extended-spectrum beta-lactamases (ESBLs) are spreading worldwide. (who.int)
Resistance2
  • Resistance to methicillin - that indicates resistance to all beta-lactam agents - was first reported in 1961, the date that marks the appearance of Methicillin-resistant S. aureus (MRSA). (frontiersin.org)
  • in citrobacter freundii, cefamandole resistance was transferred always with cephalotin resistance as well as with a tem-like beta lactamase (conferring resistance to ampicillin, carbenicillin and azlocillin). (liverpool.ac.uk)
Inhibitor1
  • On August 14, Entasis announced positive topline results from its Phase II clinical trial of ETX2514, a beta-lactamase inhibitor, in combination with sulbactam, to treat complicated urinary tract infections (cUTI) including acute pyelonephritis (kidney infection) in adults. (biospace.com)
CD204
  • Rituximab (RTX) is a CD20‑targeting antibody that is the standard‑of‑care for patients with non‑Hodgkin Lymphoma (NHL) cases. (spandidos-publications.com)
  • Taken together, these findings warranted further investigation on NAV‑006 as a next generation anti‑CD20 antibody that could improve the efficacy of parent RTX in NHL patients with high levels of CA125. (spandidos-publications.com)
  • This strategy includes the monoclonal anti-CD20 antibody, rituximab (RTX), alone or in combination with chemotherapy for patients who have advanced-stage disease. (spandidos-publications.com)
  • The mechanisms of action by which RTX kills FL cells include complement-dependent cytotoxicity (CDC) ( 3 ), antibody-dependent cellular cytotoxicity (ADCC) ( 4 , 5 )-herein referred to as 'effector function' mechanisms-as well as CD20 signaling effects ( 6 ). (spandidos-publications.com)
Fragment1
  • Examples include chimeric and humanized minretumomab, as well as a fusion protein of a minretumomab single-chain variable fragment and the enzyme beta-lactamase. (wikipedia.org)
Detection1
  • The Rapid Screening Test (RST) was used for the detection of Dengue-specific IgG and IgM antibodies. (bvsalud.org)
Bacteria2
  • They are more active against lactamases produced by bacteria. (howmed.net)
  • Immunity produced when an animal's own immune system reacts to a stimulus e.g., a virus or bacteria, and produces antibodies and cells which will protect it from the disease caused by the bacteria or virus. (mysanantoniovet.com)
Activates1
  • In HIT, platelet factor 4 forms multimolecular complexes with heparin that trigger the formation of antibodies and activates platelets. (consultant360.com)
Antigen2
  • Minretumomab (CC49) is a mouse monoclonal antibody that was designed for the treatment of cancers that express the TAG-72 antigen. (wikipedia.org)
  • Genemedi developed the antigen and antibody to detect the non-infectious disease such as immune dysfunction, abortion and teratology, nonbacterial diarrheic disease, Prion associated diseases (Scrapie, Bovine Spongiform Encephalopathy, Chronical Waste Disease), winter dysentery and so on. (genemedi.com)
Gene2
  • AP-1 activation was assessed using an ME180 cell line stably transfected with a beta-lactamase reporter gene under the control of AP-1 response element following epidermal growth factor (EGF) stimulation. (biomedcentral.com)
  • We used a cell-based human FXR β-lactamase ( Bla ) reporter gene assay to profile the Tox21 10K compound collection of environmental chemicals and drugs. (nature.com)
Viral2
  • The research in my lab is at the interface of chemistry and biology to investigate the molecular basis of diseases and discover novel therapeutic/technological approaches (e.g., ligands, biodrugs, nanodiscs, targeted nanovectors, lipid-nanoparticles for nucleic acid delivery, engineered viral cages and antibodies). (iit.it)
  • nanoBIOTECHNOLOGY , with applications that range from design and generation of bioactive 3D (nano-)biomaterials (e.g., nanodiscs, targeted nanovectors, lipid-nanoparticles for nucleic acid delivery, engineered viral cages and antibodies) to biodrugs and cascade biocatalysts in sustainable technology. (iit.it)
Blockers1
  • He had received heparin for deep vein thrombosis prophylaxis and during dialysis, but he was not on any other medications known to cause thrombocytopenia, such as H2 blockers and beta-lactamase antibiotics. (consultant360.com)
Drugs1
  • Drugs having beta lactam molecules are not clinically given alone. (howmed.net)
Diagnostics1
  • From this initial study, we conclude that measurement of antibody and of cellular (IFN-γ) responses to brucellergene OCB protein epitopes may be worthy of further investigation as an alternative or adjunct to current diagnostics. (ox.ac.uk)
Responses2
  • Comparison of total antibody and interferon-γ T-cell responses in patients following infection with brucellosis in Georgia. (ox.ac.uk)
  • the control patients had the best antibody responses in the igg and iga antibody classes and the renal allograft recipients in the igm class. (liverpool.ac.uk)
Subunit2
  • The basic subunit of beta-crystallins. (lookformedical.com)
  • A hottest embodiment makes use of a novel human monoclonal antibody that binds to a conserved space of the gp41 transmembrane subunit of the virus. (kits-elisa.com)
Patients7
  • Blankenberg-Sprenkels SD, Fielder M, Feltkamp TW et al (1998) Antibodies to Klebsiella pneumoniae in Dutch patients with ankylosing spondylitis and acute anterior uveitis and to Proteus mirabilis in rheumatoid arthritis. (springer.com)
  • Chou CT, Uksila J, Toivanen P (1998) Enterobacterial antibodies in Chinese patients with rheumatoid arthritis and ankylosing spondylitis. (springer.com)
  • Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled trial. (tropmedres.ac)
  • We aimed to explore the potential benefit and safety of selectively blocking the anaphylatoxin and complement protein C5a with the monoclonal antibody IFX-1 (vilobelimab), in patients with severe COVID-19.MethodsWe did an exploratory, open-label, randomised phase 2 trial (part of the adaptive phase 2/3 PANAMO trial) of intravenous IFX-1 in adults with severe COVID-19 at three academic hospitals in the Netherlands. (tropmedres.ac)
  • Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants. (lookformedical.com)
  • persistence of antibodies to pneumococcal vaccine in patients with chronic renal failure. (liverpool.ac.uk)
  • antibody response to the 14-valent pneumococcal capsular polysaccharide vaccine was measured by the enzyme-linked immunosorbent assay (eia) in 17 renal allograft recipients, 29 azotemic, 11 hemodialysis, and 33 control patients. (liverpool.ac.uk)
Proteins1
  • The invention provides antibodies that bind to a plurality of β-chemokines, particularly monocyte chemotactic proteins MCP-1, MCP-2 and MCP-3. (justia.com)
Cellular1
  • RTX's mechanism of action includes complement‑dependent cytotoxicity (CDC) and antibody‑dependent cellular cytotoxicity (ADCC). (spandidos-publications.com)
Clinical2
  • 11 The patient did not have positive HIT antibodies and serotonin release assay nor had the other clinical criteria. (consultant360.com)
  • Previous clinical evidence suggested that high levels of serum CA125 have a negative impact on the effectiveness of the experimental therapeutic antibodies farletuzumab and amatuximab ( 13 - 15 ). (spandidos-publications.com)
Https1
  • Although approved for use in some countries, as of fall, 2006, clenbuterol is not an ingredient of any therapeutic drug approved by the U. Food and Drug Administration, https://tabletshome.com/clenbuterol-antibody-buy-clenbuterol-40mcg/ . (baranbaspar.com)
Peptide2
  • The conserved space positive by the neutralizing antibody is a peptide of roughly 12 amino acids in dimension and ideally 8-10 amino acids. (kits-elisa.com)
  • The present invention is extra directed to a package deal and a means for detecting the presence and determining focus of an antibody that inhibits HIV-1 fusion-associated epitope, a peptide on gp41 with the amino acid sequence represented by GCSGKLIC. (kits-elisa.com)
Human1
  • The antibody is produced by regular cell traces developed using human B lymphocyte cells collected from a affected individual possessing extreme titers of anti-HIV antibodies. (kits-elisa.com)
Cells1
  • The invention also provides cells producing the antibodies, and methods of making and using the same. (justia.com)
Production1
Cell1
Small1
  • Its lead product candidate is vibregron, an oral, once-daily, small molecule beta-3 agonist. (biospace.com)
Virus1
  • Les examens ont été réalisés au Centre d'Infectiologie Charles Mérieux (CICM) de Bamako avec le dépistage du génome des virus responsables de la Dengue, de la fièvre de la Vallée du Rift, et du Zika à l'aide de la technique de la RT-PCR en temps réel. (bvsalud.org)
Presence1
  • Eventually, this effect was shown to depend on the presence of a specific antibody against the type b capsule. (medscape.com)
Similar1
  • Gamma-crystallins are similar in structure to BETA-CRYSTALLINS in that they both form into a Greek key-like structure. (lookformedical.com)
Properties1
  • Clenbuterol is a substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. (baranbaspar.com)