• Health benefits that are associated with the use of garlic are attributed to its anticancer, anti-inflammatory, antifungal, antiviral, and antibacterial activity. (frontiersin.org)
  • The antiviral, antibacterial, and anticancer properties of its chemo-skeleton have motivated this study to explore its efficacy in pharmaceutics. (nih.gov)
  • Taken together, the incorporation of [pineapple peel powder] and probiotics in yogurts offers new opportunities in the development of novel functional foods, and this approach could lead to the development of novel bioactive peptides having antibacterial and anticancer activity," concluded the authors of one study investigating the antibacterial effects of yogurt. (mdlinx.com)
  • Cordycepin exhibits various bio-activities, including anticancer, antibacterial, antiviral and immune regulation activities, and is a significant focus of research. (spandidos-publications.com)
  • Cordycepin ( Fig. 1A ) with the molecular formula C 10 H 13 N 5 O 3 has been demonstrated to have various bio-activities, including anticancer ( 4 - 7 ), antibacterial ( 8 ), antiviral ( 9 , 10 ) and immune regulation activities ( 11 ) and has became a topic of interest to various research groups. (spandidos-publications.com)
  • A large body of epidemiological studies has proven the bioactivities of phenolics in both standard compounds and natural extracts: namely, anticancer, anti-inflammatory, and antibacterial activities as well as reducing diabetes, cardiovascular disease, and neurodegenerative disease. (mdpi.com)
  • All the compounds were screened for their tuberculostatic, antibacterial, and anticancer activities. (springer.com)
  • The synthesized compounds were evaluated for their biological activity in vitro: tuberculostatic, antibacterial, cytotoxic, and anticancer. (springer.com)
  • The antibacterial activity against various pathogenic and drug-resistant bacteria was tested using crude garlic extracts, garlic powder (GP), garlic extracts using various solvents, GO, and phytochemicals isolated from garlic. (frontiersin.org)
  • In the present work, we identified the volatile compounds of ethanol extracts of Melissa officinalis, Mentha sp. (fiocruz.br)
  • Phytol was a compound identified in all extracts by GC/MS, being majoritary component in Plectranthus barbatus and Rosmarinus officinalis. (fiocruz.br)
  • These results encourage additional studies, in order to evaluate the possibilities of using ethanol extracts of Lamiaceae family as natural source for antibacterial activity. (fiocruz.br)
  • Both in vitro and in vivo studies with the aim of relating antimicrobial and antioxidant properties of extracts, fractions, synergistic mixtures, and single pure compounds to possible treatments of human disorders and diseases are encouraged. (hindawi.com)
  • We also welcome the submission of research articles studying the chemical structure of extracts, fractions, and isolated pure compounds. (hindawi.com)
  • All extracts and the isolated and synthesized compounds were subjected to screening of bioactivity for medical, cosmetic, and plant protection purposes, for industrial applications, and the use of the total or remaining biomass in production of growth substrates, organic fertilizers, and bioremediation materials was investigated. (europa.eu)
  • Additionally, all proposed inhibitors demonstrate robust predicted binding modes unaffected by the G196S and N263K mutations with one of the synthesized compounds demonstrating in vitro antibacterial activity against S. aureus. (biosolveit.de)
  • citation needed] It may has in vitro antibacterial properties. (wikipedia.org)
  • Pharmacology studies on P . oleracea have also showed its significant antibacterial effects on the enteropathogenic bacteria, which might reveal the treatment of P . oleracea in cases of bacillary dysentery to some extent. (mdpi.com)
  • The researchers separated the hemp leaf extract into fractions using high-performance liquid chromatography (HPLC) and screened these for activity against E. coli - identifying two fractions with significant antibacterial activity. (elgalabwater.com)
  • Compounds 14-19, 21, 34, 31, and 30 demonstrated significant antibacterial activities with MIC values of 15.625 μg/ml. (uwc.ac.za)
  • It has a wide range of nutritional and bioactive compounds, including essential amino acids, carbohydrates, fiber, vitamins, minerals and phytonutrients, making this plant a powerful one. (yahoo.com)
  • That includes key nutrients like calcium , iron , B vitamins, potassium, magnesium and vitamin C . Overall, moringa is rich in macro- and micronutrients and other bioactive compounds which are vital for the normal functioning of the body and prevention of many diseases. (yahoo.com)
  • The principal phytochemicals that exhibit antibacterial activity are oil-soluble organosulfur compounds that include allicin, ajoenes, and allyl sulfides. (frontiersin.org)
  • The organosulfur compounds of garlic exhibit a range of antibacterial properties such as bactericidal, antibiofilm, antitoxin, and anti-quorum sensing activity against a wide range of bacteria including multi-drug resistant (MDR) strains. (frontiersin.org)
  • Separation and Identification of Four New Compounds with Antibacterial Activity from Portulaca oleracea L. (mdpi.com)
  • Researchers identify two hemp compounds with antibacterial activity that offer promise for a variety of applications in the food, pharmaceutical and cosmetic industries. (elgalabwater.com)
  • The team screened the antibacterial activity of hemp leaf extract against three species of bacteria: Escherichia coli, Staphylococcus aureus, and Bacillus cereus. (elgalabwater.com)
  • This study presents evidence of the antibacterial activity of industrial hemp leaf extract on E. coli and S. aureus. (elgalabwater.com)
  • The discovery that cannabidivarinic acid and cannabidiolic acid possess antibacterial activity makes these compounds good candidates for a variety of applications in the food, cosmetic and pharmaceutical industries. (elgalabwater.com)
  • So our aim is to isolate the triterpenoidal compounds from dichloromethane fraction (DCMF) of Calothamnus quadrifidus R.Br leaves and in addition to evaluate the antibacterial activity of the isolated compounds. (biomedcentral.com)
  • Compounds 4 and 5 showed strong antibacterial activity against S. typhimurium while compound 4, 5 and 3, 4 exhibits moderate effect against E.coli and S. aureus respectively. (biomedcentral.com)
  • There were no reports about investigation of the triterpenoidal content, so we deemed it of interest to isolate and identify the triterpene compounds from DCMF of C. quadrifidus leaves and to evaluate the antibacterial activity of the pure isolates. (biomedcentral.com)
  • Volatile compounds of Lamiaceae exhibit a synergistic antibacterial activity with streptomycin. (fiocruz.br)
  • In one study, the strongest antibacterial activity was observed against Streptococcus mutans, an organism known to cause tooth decay in humans. (wikipedia.org)
  • The broad‐spectrum antibacterial activity exhibited by three Pediococcus strains isolated from beer was preliminarily characterized. (vtt.fi)
  • The antibacterial activity against a range of Gram‐negative test organisms was not affected by catalase or proteolytic enzymes and was extremely thermotolerant. (vtt.fi)
  • Antibacterial activity against gram-negative and gram-positive bacteria was determined by agar diffusion test. (utb.cz)
  • In the present study a compound ascidia Aplidium multiplicatum, collected from Vizhinjam, south west coast of India was assayed for their antibacterial activity against six human bacterial pathogens. (ijsrp.org)
  • The antibacterial activity of crude extract of ascidians showed inhibitory activity against all six species. (ijsrp.org)
  • The crude methanol extract was more active exhibiting a broad spectrum antibacterial activity than the crude ethanol and acetone extract against each of the bacterial species tested. (ijsrp.org)
  • In antibacterial activity the gram negative bacteria Pseudomonas aeruginosa showed most sensitive against 12.0533± 0.010116 mm A.multiplicatum in crude methanol extract. (ijsrp.org)
  • Compound X5, X14 and a 11 mixture of X5 and X6 showed comparative anti-inflammatory activity to dexamethasone . (bvsalud.org)
  • Interestingly, moringa has been shown in several studies to have greater antibacterial activity against gram-positive bacteria, such as Staph . (mdlinx.com)
  • Although studies have shown that cordycepin is a broad-spectrum antibiotic ( 18 ), studies focusing on the mechanism of the antibacterial activity and the possible targets are lacking. (spandidos-publications.com)
  • To contribute to the development of antibacterial products from propolis produced by native Brazilian bees, twenty-nine samples of propolis collected from hives in the state of Minas Gerais, Brazil, were screened for in vitro activity against Aeromonas hydrophila, Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus. (scielo.br)
  • Both the parent compound and the metabolite possess in vitro bactericidal activity against most strains of anaerobic bacteria. (nih.gov)
  • Efficiency of green tea extract in oral hygiene has been known for centuries and this gave researchers a clue that antibacterial activity might be involved. (sciencedaily.com)
  • Fig. 2: Synthesis and antibacterial activity of syn-BNPs based on BGCs predicted to encode MBAs. (nature.com)
  • The anti‐proliferative activity of all newly synthesized compounds has been assessed against six human solid tumor cell lines. (researchgate.net)
  • Seven compounds show good activity against single cell line whereas, compounds having a pyridine scaffold showed significant anti‐proliferative activity. (researchgate.net)
  • All newly synthesized compounds were screened for anti‐proliferative activity against different human tumor cell lines. (researchgate.net)
  • Compound 5 showed high antiproliferative activity against several human tumor cell lines. (researchgate.net)
  • Seven compounds inhibited the growth of some cancer cell lines, whereas one of the 2-quinoline derivatives displayed favorable activity against all tested cancer cells with GI 50 values of 0.92-13 μM. (springer.com)
  • Sulfonamides are compounds with diverse pharmacological activity. (springer.com)
  • The amidine functional group is an important structural element of compounds with established pharmacological activity. (springer.com)
  • Although the seed oil showed antibacterial activity, it didn't show any antifungal activity. (who.int)
  • The oil also showed marked antibacterial activity. (who.int)
  • The peer-reviewed literature reported antibacterial, antifungal, antiprotozoal, antituberculosis, and antiviral activities for 123 marine natural products, 111 marine compounds with antidiabetic and anti-inflammatory activities as well as affecting the immune and nervous system, while in contrast 79 marine compounds displayed miscellaneous mechanisms of action which upon further investigation may contribute to several pharmacological classes. (elsevierpure.com)
  • Active compounds like catechin, quercetin, and chlorogenic acids may be credited for the anti-cancer, antioxidant and antiviral properties of apricots. (livescience.com)
  • We demonstrate that biologically relevant compounds such as glutathione, cysteine and human blood components significantly reduce the toxicity of silver ions to clinically relevant pathogenic bacteria and primary human dermal fibroblasts (skin cells). (bath.ac.uk)
  • The results revealed that final composites exhibit sufficient antibacterial properties against tested bacteria, with nonuniform distribution of silver particles in the PVC matrix, which caused a decrease in mechanical properties. (utb.cz)
  • With an ongoing increase in drug-resistant bacteria , research is investigating natural compounds as a potential source and inspiration for new antimicrobial agents. (medicalnewstoday.com)
  • A 2021 review notes that these compounds may be effective against multi-drug resistant bacteria and can provide a framework for the development of future antibiotics. (medicalnewstoday.com)
  • A 2022 article notes that echinacea has an antibacterial effect on respiratory bacteria. (medicalnewstoday.com)
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of Metronidazole Injection USP and other antibacterial drugs, Metronidazole Injection USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
  • Up to now several compounds targeted against the ATP-binding site of bacteria gyrase have been known but couldn't be used as drugs due to their side effects on mammalian cells. (sciencedaily.com)
  • Because garlic stops microorganisms (such as bacteria) from reproducing, it has some antiseptic and antibacterial effects. (msdmanuals.com)
  • Many studies have investigated the antioxidant properties of natural products, but despite the large number of natural products that are currently studied, the search for new natural compounds with antimicrobial and antioxidant activities still remains a growing research area. (hindawi.com)
  • This special issue aims to highlight the recent research on new trends and on new antimicrobial and antioxidant natural compounds obtained from medicinal plants. (hindawi.com)
  • Two compounds of note are quercetin, a potent antioxidant and anti-inflammatory agent, and isothiocyanates, which aid in detoxification and have anti-inflammatory effects," Smith says. (yahoo.com)
  • However, the antibacterial efficacy varied with bacterial species and strains. (nih.gov)
  • All isolated anthraquinones showed moderate-to-high antibacterial efficacy while compound A3 also demonstrated moderate anti-inflammatory effect. (bvsalud.org)
  • Microbiological studies of this oil indicated that both these oils have shows antibacterial and antifungal activities. (who.int)
  • Exposure to the antimicrobial compounds triclosan and triclocarban may affect not only our ability to fight off germs, but also the birth length of newborns. (medicaldaily.com)
  • Nowadays, plants are considered a valuable source of unique natural compounds used in the development of antidiabetic, anti-inflammatory, anticancerous, and antimicrobial drugs. (hindawi.com)
  • Therefore, molecular docking was also used in the present study to simulate the binding of cordycepin with different antibacterial targets, such as β-ketoacyl-(acyl-carrier-protein) synthase III (FabH), DNA gyrase B and thymidylate kinase, in order to identify the most likely antimicrobial mechanism of cordycepin. (spandidos-publications.com)
  • A 2022 review notes that the antimicrobial effect of oregano oil may be due to a compound known as carvacrol. (medicalnewstoday.com)
  • It has been reported that the antibacterial and cytotoxic properties of silver are affected by the assay conditions, particularly the type of growth media used in vitro. (bath.ac.uk)
  • Mulley, G , Jenkins, ATA & Waterfield, NR 2014, ' Inactivation of the antibacterial and cytotoxic properties of silver ions by biologically relevant compounds ', PLoS ONE , vol. 9, no. 4. (bath.ac.uk)
  • But the potential applications for hemp-derived materials with antibacterial properties extend beyond medications - for example, as natural preservatives in food packaging and cosmetics. (elgalabwater.com)
  • The oil-based emulsion system was also tested for its antibacterial properties against Staphylococcus aureus . (nih.gov)
  • Although plenty of prescription antibiotics are available, the threat of antibiotic resistance has sparked interest in foods that have antibacterial properties. (mdlinx.com)
  • Several compounds in garlic have natural antibacterial properties . (medicalnewstoday.com)
  • These include compounds such as allicin, ajoenes, and allyl sulfides, which exhibit a range of antibacterial properties. (medicalnewstoday.com)
  • Silver is increasingly being used in garments to exploit its antibacterial properties. (cdc.gov)
  • These compounds have been shown to have strong anti-inflammatory and antibacterial properties. (livescience.com)
  • higher homologs have hemostatic and antibacterial properties. (bvsalud.org)
  • Antibacterial activities of the isolated compounds were evaluated using agar well diffusion method while minimum inhibitory concentration was assessed by microtiter plate assay method. (biomedcentral.com)
  • Compounds 29 and 34 were more cytotoxic than ursolic acid, with IC50 values of 46.99 and 48.18 μg/ml. (uwc.ac.za)
  • The Pharmabees team is studying honey to investigate antibacterial phytochemicals. (cardiff.ac.uk)
  • We evaluated the effectiveness of seven commercial hydrolytic enzymes to simultaneously hydrolyze N-glucuronides (using the antibacterial triclocarban as example compound) and other conjugates (using select phenols and parabens as examples) by using on-line solid phase extraction-high performance liquid chromatography-isotope dilution-tandem mass spectrometry. (cdc.gov)
  • Wounding and UVB Light Synergistically Induce the Biosynthesis of Phenolic Compounds and Ascorbic Acid in Red Prickly Pears ( Opuntia ficus-indica cv. (mdpi.com)
  • This finding may be used to develop even more potent antibacterial compounds. (sciencedaily.com)
  • By application of the three fractions on TLC and spraying with p -anisaldehyde / sulphuric acid reagent which is characteristic for terpenoidal compounds [ 5 ], it was found that the DCMF is rich in terpenoidal compounds than other two fractions. (biomedcentral.com)
  • These transformations tolerated a broad range of the nucleophilic reagents thus allowing the synthesis of a wide variety of hetero- and carbocyclic compounds including the derivatives of pyridine, pyrimidine, pyrazole, pyran, dioxane, and isoxazole as well as their heterofused derivatives. (researchgate.net)
  • Phenolic compounds were extracted with food grade solvent of acidified aqueous ethanol from leaves, berries, berry press cakes, and branches of Finnish berry plants and analyzed with HPLC-DAD, UPLC-DAD-ESI-MS and NMR. (nih.gov)
  • Antibacterial, anti-inflammatory and anti-oxidatant activities of various isolated compounds from Cratoxylum species. (bvsalud.org)
  • The objective of this study was to investigate the bioactivity of twenty-nine known isolated compounds from Cratoxylum species including three anthraquinones , four triterpenes , and twenty-two xanthones . (bvsalud.org)
  • EP0750901A2 ] The invention provides an antibacterial oral composition containing an antibacterial compound such as Triclosan and a monoalkyl phosphate compound whereby the uptake and retention of the antibacterial compound on dental tissue is substantially increased due to the presence of the monoalkyl phosphate compound. (epo.org)
  • Several triterpene and xanthone compounds also expressed antibacterial effect against P. gingivalis. (bvsalud.org)
  • This compound has a chlorine atom in its structure linked to the quinoxaline ring (C-5) substituted at the C-2 position with a sulfanilamide moiety. (springer.com)
  • Accordingly, selected pure compounds from plants of Cratoxylum genus might be of benefit in developing medications that are important in treating periodontal diseases . (bvsalud.org)
  • Pure triterpenoidal compounds isolated from C. quadrifidus leaves showed antibacterial activities in different strengths. (biomedcentral.com)
  • The antibacterial activities were investigated against various Gram-negative and Gram-positive foodborne pathogens. (nih.gov)
  • All isolated compounds were subjected to antibacterial, anti-inflammatory and anti-oxidant activities. (bvsalud.org)
  • Preliminary results indicated that target compounds exhibited weak tuberculostatic and antibacterial activities. (springer.com)
  • The review provides a focused and comprehensive portrait of the status of garlic and its compounds as antibacterial agents. (frontiersin.org)
  • Since then, extensive research has been performed on the antibacterial effects of garlic. (frontiersin.org)
  • Aged garlic extract (AGE), made from garlic allowed to age for at least 20 months, has more stable active compounds than most forms. (msdmanuals.com)
  • The review is summarized and systematized the published data on the multicomponent reactions of ethyl trifluoroacetoacetate, carbonyl compounds (aldehydes and ketones), and nucleophilic reagents. (researchgate.net)
  • Major compounds of this oil were identified as ethyl cinnamate and ethyl p-methoxycinnamate. (who.int)
  • For example, a 2023 study highlights that oregano oil may be a potential antibacterial agent that is effective against streptococcus mutans. (medicalnewstoday.com)
  • These findings prompted us to extend our search for biologically active compounds among nitrogen heterocyclic derivatives. (springer.com)
  • Moringa contains inflammation-fighting nutrients including phytonutrients, antioxidants and antibacterial compounds," says Smith. (yahoo.com)
  • One study suggests that these specific compounds found in moringa may help alleviate low-grade inflammation associated with chronic diseases. (yahoo.com)
  • The team then performed a series of experiments to explore the mechanism of action of these compounds. (elgalabwater.com)
  • Cinnamon extract is mostly made up of cinnamaldehyde and eugenol, which are compounds that attack respiratory and gastrointestinal pathogens. (mdlinx.com)
  • Known and predicted inhibitors of FtsZ in addition to predicted targets of known FtsZ inhibitors, comprised of 98,032 compounds, formed the initial seed set of compounds. (biosolveit.de)
  • Similarly, a 2020 article notes that clove extract may have potential as a new antibacterial agent. (medicalnewstoday.com)
  • The results of computational molecular docking analysis indicated that the interaction energy between cordycepin and NAD+‑dependent DNA ligase (LigA) was lower than that between cordycepin and other common antibacterial targets. (spandidos-publications.com)
  • Using analytical HPLC, they went on to reveal the identity of the two active compounds as cannabidivarinic acid and cannabidiolic acid. (elgalabwater.com)
  • Together, these powerful compounds fight inflammation in the body by targeting free radicals (compounds that damage cells) and as a result reduces oxidative stress, inflammation and fights disease. (yahoo.com)
  • We determined the antibacterial effective fraction of P . oleracea in a previous study. (mdpi.com)
  • The reactive organosulfur compounds form disulfide bonds with free sulfhydryl groups of enzymes and compromise the integrity of the bacterial membrane. (frontiersin.org)
  • Honey could help provide an alternative antibacterial agent with promising therapeutic potential. (medicalnewstoday.com)
  • To boot, consumers seem to be interested in minimally processed foods with antibacterial effects-so a market for these products exists. (mdlinx.com)