• Our objectives were to investigate the effect of broad (BS) versus narrow (NS) spectrum antianaerobic antibiotic activity on lung microbiome diversity and pulmonary function, hypothesizing that BS antibiotics would cause greater change in microbiome diversity without a significant improvement in lung function. (lww.com)
  • Often, the exact species of bacteria causing the illness is unknown, in which case narrow-spectrum antibiotics can't be used, and broad-spectrum antibiotics are used instead. (wikipedia.org)
  • citation needed] Antimicrobial spectrum Broad-spectrum antibiotics Hopkins SJ (1997). (wikipedia.org)
  • Erythromycin is a broad-spectrum, macrolide antibiotic with antibacterial activity. (synzeal.com)
  • Analysed target's ability to act as generalized broad-spectrum drug/vaccine target. (blogspot.com)
  • The current study aims at prioritizing broad-spectrum antibacterial targets, present in multiple food and waterborne bacterial pathogens, through a comparative genomics strategy coupled with a protein interaction network analysis. (blogspot.com)
  • The analyses revealed a set of promising broad-spectrum antibacterial targets, present in multiple food and waterborne pathogens, which are essential for bacterial survival, non-homologous to host and gut flora, and functionally important in the metabolic network. (blogspot.com)
  • The identified broad-spectrum candidates, namely, integral membrane protein/virulence factor (MviN), preprotein translocase subunits SecB and SecG, carbon storage regulator (CsrA), and nitrogen regulatory protein P-II 1 (GlnB), contributed by the peptidoglycan pathway, bacterial secretion systems and two-component systems, were also found to be present in a wide range of other disease-causing bacteria. (blogspot.com)
  • The identified broad-spectrum targets can aid in the design and development of antibacterial agents not only against food and waterborne pathogens but also against other pathogens. (blogspot.com)
  • Doxycycline is a broad-spectrum antibacterial synthetically derived from oxytetracycline. (nih.gov)
  • The findings published in Nature [1] indicate that this bactericidal antimicrobial biomaterial could be utilized to eradicate a broad spectrum of bacteria and fungi as well as antibiotic-resistant pathogens in the health, agricultural and environmental industries. (yissum.co.il)
  • As a platform technology, aap 's antibacterial silver coating technology has a broad spectrum of applications. (pharmiweb.com)
  • In view of this and of its broad spectrum of applications, aap 's antibacterial silver coating technology offers enormous market potential. (pharmiweb.com)
  • In search of broad-spectrum antibacterial activity from traditionally used Indian medicinal plants, 66 ethanolic plant extracts were screened against nine different bacteria. (unboundmedicine.com)
  • Twelve extracts showing broad-spectrum activity were tested against specific multidrug-resistant (MDR) bacteria, methicillin-resistant Staphylococcus aureus (MRSA) and extended spectrum beta-lactamases (ESbetaL)-producing enteric bacteria. (unboundmedicine.com)
  • Gram-positive and Gram-negative MDR bacteria are almost equally sensitive to these extracts/fractions, indicating their broad-spectrum nature. (unboundmedicine.com)
  • AU - Aqil,F, AU - Ahmad,I, PY - 2007/4/19/pubmed PY - 2007/6/27/medline PY - 2007/4/19/entrez SP - 79 EP - 92 JF - Methods and findings in experimental and clinical pharmacology JO - Methods Find Exp Clin Pharmacol VL - 29 IS - 2 N2 - In search of broad-spectrum antibacterial activity from traditionally used Indian medicinal plants, 66 ethanolic plant extracts were screened against nine different bacteria. (unboundmedicine.com)
  • It has a broad spectrum of antibacterial activity. (guidechem.com)
  • This study shows a broad spectrum and great therapeutic potential of the plant with the ability to attract significant scientific attention. (academicjournals.org)
  • Gatifloxacin is an 8-methoxy fluoroquinolone that shows a broad spectrum and increased antibacterial activities against Gram-positive cocci bacteria, anaerobes, chlamydias and mycoplasmas. (bmj.com)
  • Bismuth oxide is a photocatalyst with broad absorption spectrum it is capable of eliminating organic molecules. (hiphopgalaxy.com)
  • With the exception of some spore-forming bacteria and envelope-lacking viruses, ethanol shows a broad antibacterial and antiviral spectrum. (medsci.org)
  • Effective broad spectrum antibacterial and antifungal. (petsupplies4less.com)
  • The risk factors for candid are sometimes we call in the fungal world the other C. diff , have somewhat similar characteristics in that broad spectrum antibacterial use is a very common association with those who develop infections due to Candida . (cdc.gov)
  • And it makes some sense because we use broad spectrum antibiotics and tend to eliminate all the good and bad bacteria, if they exist, and what's left, fungus. (cdc.gov)
  • Clotrimazole is a broad-spectrum antifungal agent that inhibits yeast growth by altering cell membrane permeability, causing death of fungal cells. (medscape.com)
  • It is a synthetic oral antifungal (broad-spectrum bistriazole) that selectively inhibits fungal cytochrome P-450 and sterol C-14 alpha-demethylation, which prevents the conversion of lanosterol to ergosterol, thereby disrupting cellular membranes. (medscape.com)
  • There is a need for isolation of a broad spectrum of antibiotics from microorganisms due to the emergence of antibiotic resistance . (bvsalud.org)
  • Therefore, it could be used for preparing broad-spectrum antibacterial agents. (bvsalud.org)
  • A drug combination with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. (bvsalud.org)
  • The synthesized compounds were evaluated for their biological activity in vitro: tuberculostatic, antibacterial, cytotoxic, and anticancer. (springer.com)
  • The present study was aimed to analyse in vitro , the antibacterial and antifungal activities of the leaf extracts of Melia azedarach . (ijpsonline.com)
  • A narrow-spectrum antibiotic is an antibiotic that is only able to kill or inhibit limited species of bacteria. (wikipedia.org)
  • Narrow-spectrum antibiotic allow to kill or inhibit only those bacteria species that are unwanted (i.e. causing disease). (wikipedia.org)
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of doxycycline capsules and other antibacterial drugs, doxycycline capsules should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
  • Ethyl acetate, acetone and methanol fractions of more than six plants indicated that the active phytocompounds were distributed mainly into acetone and ethyl acetate fractions, whereas they were least prevalent in methanol fractions as evident from their antibacterial activity against MDR bacteria. (unboundmedicine.com)
  • The organosulfur compounds of garlic exhibit a range of antibacterial properties such as bactericidal, antibiofilm, antitoxin, and anti-quorum sensing activity against a wide range of bacteria including multi-drug resistant (MDR) strains. (frontiersin.org)
  • The antibacterial activity against various pathogenic and drug-resistant bacteria was tested using crude garlic extracts, garlic powder (GP), garlic extracts using various solvents, GO, and phytochemicals isolated from garlic. (frontiersin.org)
  • Bismuth oxide nanoparticles displayed antibacterial properties against Gram-negative as well as Gram-positive bacteria. (hiphopgalaxy.com)
  • Antibacterial and antifungal activity was measured using agar well diffusion assay and broth microdilution methods, respectively against different pathogenic bacteria and fungi. (ijpsonline.com)
  • Purpose: To evaluate the antibacterial effect of four oral antiseptics (two solutions of cetylpyridinium chloride, chlorhexidine gluconate and benzalkonium chloride) on facultative bacteria using two methods. (bvsalud.org)
  • Overview of Antibacterial Drugs Antibacterial drugs are derived from bacteria or molds or are synthesized de novo. (msdmanuals.com)
  • Ornidazole, as one of the common drugs for filling therapy in recent years, is included in the category of nitroimidazoles, which contain nitro that can be successfully reduced to amino under anaerobic conditions, thus accelerating the extinction of microorganisms and exerting significant antibacterial efficacy [ 5 ]. (hindawi.com)
  • All parts showed low to significant antibacterial activity against the mentioned bacterial strains. (academicjournals.org)
  • The inclusion of step-down units and general hematology-oncology units in adult 2017 baseline SAAR models and the addition of SAARs for narrow-spectrum beta-lactam agents, antifungals predominantly used for invasive candidiasis, antibacterial agents posing the highest risk for Clostridioides difficile infection, and azithromycin (pediatrics only) expand the role SAARs can play in ASP efforts. (cdc.gov)
  • Health benefits that are associated with the use of garlic are attributed to its anticancer, anti-inflammatory, antifungal, antiviral, and antibacterial activity. (frontiersin.org)
  • Examples of narrow-spectrum antibiotics include fidaxomicin and sarecycline. (wikipedia.org)
  • Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and efficacy. (tamu.edu)
  • However, strain- and plant extract-dependent variations in the antibacterial activity were also evident. (unboundmedicine.com)
  • The principal phytochemicals that exhibit antibacterial activity are oil-soluble organosulfur compounds that include allicin, ajoenes, and allyl sulfides. (frontiersin.org)
  • Using orthodontic composite containing nonoparticles with antibacterial activity may prevent dental caries. (thejcdp.com)
  • The antibacterial activity of the methanolic extract of various parts of Rhododendron arboreum such as flowers, leaves, bark, stem and roots were investigated against medically important pathogens by determining the zone inhibition. (academicjournals.org)
  • The bioautography of TLC chromatogram showed single band exhibited antibacterial activity and phytocompound from this band was isolated and identified as 5,6,7,8-tetrahydro-1,2,4-benzotriazine-3-amine using gas chromatography-mass spectroscopy analyses. (ijpsonline.com)
  • The antibacterial effect of 0.13% benzalkonium chloride against the biological indicators was observed after five minutes in direct exposure, while cetylpyridinium chloride and chlorhexidine gluconate had an antibacterial effect against all the microorganisms after 10 minutes. (bvsalud.org)
  • When combined with the patented antimicrobial LP3 Enzyme System, the results are antibacterial and antifungal with effective biofilm destruction. (petsupplies4less.com)
  • Antibacterial agents predominantly used for resistant Gram-positive Adult, Pediatric infections (e.g. (cdc.gov)
  • The review provides a focused and comprehensive portrait of the status of garlic and its compounds as antibacterial agents. (frontiersin.org)
  • A systematic and comparative study has been made starting from a naturally-occurring chalcone nucleus to design effective antibacterial agents. (scielo.org.za)
  • ABSTRACT This study compared the utilization and cost of antibacterial agents in surgical units of 2 government hospitals in Palestine. (who.int)
  • The total consumption of antibacterial agents was 414.1 DDD and 591.5 DDD at Thabet and Rafidia hospitals respectively. (who.int)
  • RÉSUMÉ La présente étude a comparé l'utilisation et le coût des agents antibactériens dans des services de chirurgie de deux hôpitaux publics en Palestine. (who.int)
  • Faropenem sodium tablets are a type of medication specifically used for anti-inflammatory and antibacterial purposes. (guidechem.com)
  • All the compounds were screened for their tuberculostatic, antibacterial, and anticancer activities. (springer.com)
  • Conclusion: The antiseptic solutions included in this study had an antibacterial effect against S. mutans, E. faecalis, and P. aeruginosa. (bvsalud.org)
  • Multiple antibacterial effects of organosulfur compounds provide an excellent framework to develop them into novel antibiotics. (frontiersin.org)
  • were the reported increasing rates of resistance to antibiotics used second most common pathogen isolated from device- to treat P. aeruginosa infections, such as carbapenems associated HA infections in a study of intensive care and extended-spectrum cephalosporins ( Fig. 1A-B ). In units in Philippine hospitals. (who.int)
  • Preliminary results indicated that target compounds exhibited weak tuberculostatic and antibacterial activities. (springer.com)
  • However, since the antibacterial mechanism of Lla-Met is not well understood, we explored this phenomenon in the present study. (bvsalud.org)
  • They are high-purity and have antibacterial activities. (hiphopgalaxy.com)
  • The antibacterial activities were tested by well diffusion method . (bvsalud.org)
  • aap Implantate AG (" aap ") announces that it has received yesterday approval from the ethics commissions to conduct a human clinical study for its innovative antibacterial silver coating technology. (pharmiweb.com)
  • aap is the first company worldwide to test an antibacterial silver coating on anatomical plates for fracture treatment in a study of this kind. (pharmiweb.com)
  • Our previous study found that linolenic acid-metronidazole (Lla-Met) has a good antibacterial effect against H. pylori, both antibiotic-resistant and sensitive H. pylori. (bvsalud.org)
  • Bismuth's antibacterial capacity oxide was tested for salmonella ATCC 1231. (hiphopgalaxy.com)
  • The antibacterial capacity of the nanoparticles also was studied using an approach to diffusion of disks. (hiphopgalaxy.com)
  • Aqil F, Ahmad I. Antibacterial properties of traditionally used Indian medicinal plants. (unboundmedicine.com)
  • TY - JOUR T1 - Antibacterial properties of traditionally used Indian medicinal plants. (unboundmedicine.com)
  • The spectrum of absorption in the UV-visible spectrum was analysed to determine the UV protective properties of nanoparticles. (hiphopgalaxy.com)
  • Therefore, the clinical treatment of this disease is based on the principle of antibacterial therapy. (hindawi.com)
  • The mode of antibacterial action of 1c was also studied by scanning electron microscopy, which showed membrane disruption and cell lysis of the organisms during the exposure of the tested compound. (scielo.org.za)
  • Higher generations generally have expanded spectra against aerobic gram-negative bacilli. (msdmanuals.com)
  • In addition, aap Implantate AG has an innovation pipeline with promising development projects such as the antibacterial silver coating technology and magnesium-based implants. (pharmiweb.com)
  • Since then, extensive research has been performed on the antibacterial effects of garlic. (frontiersin.org)