Antiarrhythmic patients atrial flutter. Medical search. Frequent questions

Administration resulted in successful heart rhythm control in 31-44% of patients within 90 minutes, with sustained polymorphic ventricular tachycardia in 0.9-2.5% of patients. (wikipedia.org)
Tachycardia may or may not be present, depending on the degree of AV block associated with the atrial flutter activity. (medscape.com)
Sendra-Ferrer M , Gonzalez MD. Ibutilide for the control of refractory ventricular tachycardia and ventricular fibrillation in patients with myocardial ischemia and hemodynamic instability. (muhealth.org)
Atrial Fibrillation, Atrial Tachycardia: What's the Difference? (acc.org)
Prior Holter monitoring demonstrated episodes of atrial fibrillation as well as an atrial tachycardia. (acc.org)
Figure 1 is a 12-lead ECG demonstrating bursts of atrial tachycardia. (acc.org)
We then started isoproternol up to 10mcg/min with no induction of atrial tachycardia or atrial fibrillation. (acc.org)
Despite an irregularly irregular rhythm, the patient in our case suffers from a focal atrial tachycardia. (acc.org)
Focal atrial tachycardia as the sole mechanism for supraventricular tachycardia is relatively rare accounting for 10-15% of cases referred for catheter ablation. (acc.org)
(2) Although relatively rare, sustained episodes of focal atrial tachycardia may lead to a rate related cardiomyopathy. (acc.org)
In a retrospective series, only 3% of all atrial tachycardia from a large tertiary referral center was classified as pulmonary vein tachycardia. (acc.org)
(3) In this series, focal ablation of either the earliest activation site at the os of the vein, or circumferential ablation of the culprit vein resulted in favorable long term freedom from recurrent atrial tachycardia, and atrial fibrillation. (acc.org)
(4) In three large series of patients undergoing ablation for focal pulmonary vein tachycardia, the reported development of atrial fibrillation post ablation is low. (acc.org)
Figures 1 and 2 demonstrate a 12-lead electrocardiogram with bursts of atrial tachycardia and sinus rhythm. (acc.org)
Not only is the risk of death in patients with AF twice that of patients without AF, but AF can result in myocardial ischemia or even infarction, heart failure exacerbation, and tachycardia-induced cardiomyopathy if the ventricular rate is not well-controlled. (ahrq.gov)
Whether or not a rhythm-control strategy is adopted, adequate rate control should be achieved in all patients with AF to prevent myocardial infarction (if significant coronary artery disease is present), exacerbation of heart failure, and tachycardia-induced cardiomyopathy and to alleviate symptoms. (ahrq.gov)
For patient education information, see the Heart Health Center , as well as Atrial Flutter , Arrhythmias (Heart Rhythm Disorders) , Stroke , Supraventricular Tachycardia (SVT, PSVT) , and Palpitations . (medscape.com)
Recent data support the role of flecainide in preventing ventricular tachyarrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia associated both with ryanodine receptor and calsequestrin mutations. (wjgnet.com)
In patients with isthmus-dependent atrial flutter, entrainment mapping from the isthmus during tachycardia results in postpacing intervals (PPI) close to the tachycardia cycle length (TCL). (univ-brest.fr)
In all patients, RFA of the isthmus resulted in termination of tachycardia, confirming the isthmus-dependent nature of the flutter. (univ-brest.fr)
In three patients of group B, the administration of ibutilide was discontinued due to development of nonsustained ventricular tachycardia, which resolved with discontinuation of the drug. (hippokratia.gr)
Fifty one patients with electrically inducible atrioventricular re-entrant tachycardia were allocated to one of five doses of dofetilide (1.5, 3, 6, 9, and 15 μg/kg), two thirds of the dofetilide dose being given over a 15 minute loading period and the remainder over a 45 minute maintenance period. (bmj.com)
MAIN OUTCOME MEASURE Responders were defined as patients in whom dofetilide prevented reinduction of atrioventricular re-entrant tachycardia at the end of the infusion. (bmj.com)
Treatment related side effects were reported in four patients, one with a new sustained incessant supraventricular tachycardia. (bmj.com)
CONCLUSIONS Dofetilide shows promise as an agent for the prevention of atrioventricular re-entrant tachycardia in patients without structural heart disease. (bmj.com)
While class I antiarrhythmic drugs are effective in treating this form of tachycardia, there is a reluctance to use these agents, especially in patients with structural heart disease, because of potential proarrhythmia or undesirable side effects-as seen in the cardiac arrhythmia suppression trial (CAST). (bmj.com)
Our goal in this study was to assess the efficacy of intravenous dofetilide, in five different dosing regimens, for treating patients with inducible atrioventricular re-entrant tachycardia, by determining its ability to prevent reinduction of the tachycardia. (bmj.com)
However, accurate diagnostic workup of broad complex tachycardia is crucial to ensure correct indication for ICD treatment and to avoid unnecessary invasive treatment and device-associated morbidity.Case summaryWe present a case of atypical atrial flutter with 2:1 atrioventricular (AV) conduction via a left-posterior accessory pathway (AP), leading to the diagnosis of Wolff-Parkinson-White (WPW) syndrome. (deepdyve.com)
Upon admission, the 72-year-old patient showed a regular broad complex tachycardia with superior axis and positive concordance in precordial leads, suggestive of either ventricular tachycardia (VT), antidromic AV re-entrant tachycardia (AVRT), or supraventricular tachycardia with antegrade conduction via a left-posterior AP. (deepdyve.com)
However, current techniques for ablating complex arrhythmias such as atrial fibrillation and ventricular tachycardia are associated with sub-optimal success rates and prolonged radiation exposure. (rmmj.org.il)
Radiofrequency (RF) catheter ablation has advanced over the last 25 years from an experimental procedure to the first-line treatment for a number of cardiac arrhythmias including atrioventricular re - entrant tachycardia, accessory pathway-associated tachycardias, and typical atrial flutter. (rmmj.org.il)
The clinical indications for anatomy-based catheter ablation have since expanded to more complex arrhythmias such as atrial fibrillation and scar-based ventricular tachycardia. (rmmj.org.il)
The discrimination of ventricular tachycardia (VT) versus supraventricular wide complex tachycardia (SWCT) via 12-lead electrocardiogram (ECG) is crucial for achieving appropriate, high-quality, and cost-effective care in patients presenting with wide QRS complex tachycardia (WCT). (bvsalud.org)
Dofetilide has been used off-label with success in patients with paroxysmal atrial fibrillation and atrial flutter, as well as atrial tachycardia and ventricular tachycardia. (psu.edu)
Forty-seven patients (40%) experienced atrial tachyarrhythmias at a median of 3 days after surgery (70% atrial fibrillation, 22% atrial flutter, and 6% junctional tachycardia). (duke.edu)
Amiodarone is a medication primarily used to treat certain types of irregular heart rhythms, such as atrial fibrillation and ventricular tachycardia. (healthylifepharma.com)
He was hypoxic and had episodes of supraventricular tachycardia and rapid atrial flutter (ventricular rate 160-200 beats/min). (rcjournal.com)
They are said to have AF, but actually have a focal atrial tachycardia or common atrial flutter. (drjohnm.org)
This can present with palpitations or syncope from an atrioventricular reciprocating tachycardia or rarely sudden death secondary to ventricular fibrillation from rapid conduction of atrial fibrillation across the accessory pathway. (escardio.org)
5 In fact, about 11 % of patients with CHD develop atrial arrhythmias (intra-atrial reentrant tachycardia [IART] and AF), with the risk being higher in patients with right-sided heart lesions. (aerjournal.com)
These include atrial flutter, atrial tachycardia and - most commonly - AF. (aerjournal.com)
Some indications for the use of procainamide include atrial premature contractions, premature ventricular contractions, ventricular tachycardia, paroxysmal atrial tachycardia, and maintenance of a normal sinus rhythm after conversion from atrial fibrillation/flutter. (medscape.com)

Treatment involves rate control with medication, prevention of thromboembolism with anticoagulants, and often conversion to sinus rhythm with medication, cardioversion, or atrial flutter substrate ablation. (msdmanuals.com)
13 This recommendation is based on several studies that showed effective heart rate control and improvement in symptoms with AVN ablation and permanent pacemaker implantation in selected patients with AF. (ahrq.gov)
For example, patients who have the classic Fontan operation are amenable to ablation attempts of the atrial flutter in the electrophysiology laboratory because the right atrium can be approached via the inferior and/or superior vena cava. (medscape.com)
However, patients who have an extracardiac Fontan repair in which the right atrium has been bypassed with a baffle require open-heart surgery if ablation is contemplated, which is performed at the time of their Fontan revision. (medscape.com)
Biviano A, Garan H, Hickey K, Whang W, Dizon J, Rosenbaum M. Atrial flutter catheter ablation in adult patients with repaired tetralogy of Fallot: mechanisms and outcomes of percutaneous catheter ablation in a consecutive series. (medscape.com)
The aim of our study was to assess the value of entrainment mapping in the presence of amiodarone in patients undergoing radiofrequency ablation (RFA) of isthmus-dependent atrial flutter. (univ-brest.fr)
Successful targeting of ablation primarily to the anatomic arrhythmia substrate, as opposed to mapping and targeting ablation based on electrogram characteristics, began with recognition that common atrial flutter passes through a narrow structure known as the cavo-tricuspid isthmus. (rmmj.org.il)
There is limited data regarding the outcomes of AF catheter ablation in HCM patients. (bvsalud.org)
In this study, we aimed to synthesize all available evidence on the effectiveness of ablation of AF in patients with HCM compared to those without HCM. (bvsalud.org)
We included cohort studies with available quantitative information on rates of recurrent atrial arrhythmias, anti-arrhythmic drug (AAD) therapy, and repeat ablation procedures after initial AF ablation in patients with vs without HCM. (bvsalud.org)
It would be prudent to assess carefully whether patients presenting with both AF and HF will benefit from improved outcomes following restoration and maintenance of sinus rhythm, whether achieved by drug therapy or catheter ablation. (ecrjournal.com)
Pulmonary vein isolation remains the cornerstone of atrial fibrillation (AF) ablation. (jafib.com)
However, due to high recurrence rates, especially in patients with persistent AF, PV antral isolation, complemented by linear ablation, autonomic modulation, and ablation of complex fractionated electrograms, have been attempted to increase the odds of success. (jafib.com)
We performed a prospective randomized trial by assigning 92 patients with persistent AF in 1:1 ratio to pulmonary-vein isolation plus ablation of electrograms showing complex fractionated activity (45 patients), or pulmonary-vein isolation plus additional linear ablation across the left atrial roof and mitral valve isthmus (47 patients). (jafib.com)
The primary endpoint was freedom from any documented recurrence of atrial fibrillation after a single ablation procedure. (jafib.com)
At a 12-month follow-up, 9 (23%) patients had AF recurrence in the linear ablation and 8 (21%) patients in the CFAE groups. (jafib.com)
At a mean follow-up duration of 59±36 months, 48.3% of patients in the linear ablation group and 44.6% of patients in the CFAE group were free from AF (p=0.403). (jafib.com)
Among patients with persistent atrial fibrillation, we found no difference in maintenance of sinus rhythm in either linear ablation or ablation of complex fractionated electrograms was performed in addition to pulmonary vein isolation in short- and long-term follow-up. (jafib.com)
Since the seminal report by Dr. Michel Haïssaguerre, catheter-based ablation for atrial fibrillation (AF) has evolved and been highly effective for the elimination of atrial fibrillation (AF) compared to antiarrhythmic medications. (jafib.com)
However, due to a relatively high recurrence rate, especially in patients with persistent AF, other ablation techniques have been developed, involving a PV antral isolation, often complemented by ablation lines, and ablation of complex fractionated atrial electrograms. (jafib.com)
Hence we designed a prospective study to establish freedom from AF with combined wide area circumferential ablation and linear ablation, vs. combined wide area circumferential ablation and CFAE ablation in addition to antiarrhythmic therapy. (jafib.com)
We prospectively randomized patients undergoing pulmonary vein isolation to either additional linear ablation, versus the adjunctive ablation targeting fractionated or high-frequency electrograms ablation for the treatment of AF. (jafib.com)
Ninety-two patients with symptomatic persistent AF were randomized to PVI+ additional linear ablation group vs. PVI + physiology guided CFAE ablation. (jafib.com)
Catheter ablation for AF has been shown to be a very effective treatment modality in patients with refractory AF. (aerjournal.com)
However, data and guidelines regarding catheter ablation in patients with congenital heart disease are not well established. (aerjournal.com)
This review will shed light on the procedural techniques, success rates and complications of AF catheter ablation in patients with different types of CHD, including atrial septal defects, tetralogy of Fallot, persistent left superior vena cava, heterotaxy syndrome and atrial isomerism, and Ebstein anomaly. (aerjournal.com)
The 2014 American College of Cardiology/American Heart Association/Heart Rhythm Society guidelines for the management of AF describe medical therapies including rate control, rhythm control and anticoagulation, with radiofrequency catheter ablation mainly reserved for patients who are refractory or intolerant to treatment with antiarrhythmic medication. (aerjournal.com)
7 Here in this review we describe the efficacy, technical limitations and common complications of radiofrequency catheter ablation for AF in patients with different types of CHD. (aerjournal.com)
Together with Ashley, he decided to perform what's known as a hybrid ablation procedure to help better control atrial fibrillation and atrial flutter. (rush.edu)
No, it wasn't on semaglutide , or atrial fibrillation (AF) ablation, or anything about percutaneous coronary interventions (PCI). (medscape.com)

It can evaluate right and left atrial size, as well as the size and function of the right and left ventricles, and this information facilitates diagnosis of valvular heart disease, left ventricular hypertrophy (LVH), and pericardial disease. (medscape.com)
The p wave in lead V1 is entirely positive, suggesting a left atrial focus. (acc.org)
Atrioventricular 2:1-conduction via an accessory pathway during left atrial flutter unmasking WPW. (deepdyve.com)
BACKGROUND: We recently demonstrated that patients with atrial fibrillation (AF) and hypertrophic cardiomyopathy (HCM) have an increased risk of left atrial (LA) thrombus. (bvsalud.org)

Atrial flutter is a cardiac arrhythmia characterized by atrial rates of 240-400 beats/min, usually with some degree of atrioventricular (AV) node conduction block. (medscape.com)
Based on the Cardiac Arrhythmia Suppression Trial study results, flecainide is not recommended in patients with structural heart disease due to high proarrhythmic risk. (wjgnet.com)
Based on the Cardiac Arrhythmia Suppression Trial study results, flecainide is contraindicated for patients with structural heart disease due to high proarrhythmic risk. (wjgnet.com)
Several studies have shown that atrial flutter in the early postoperative period in patients who have undergone the Fontan operation predicts both early operative mortality and recurrence of the arrhythmia. (medscape.com)
If the ventricular response is slow enough to permit a sustained arrhythmia, atrial thrombosis with consequent thromboembolism may result. (medscape.com)
To minimize the risk of induced arrhythmia, patients initiated or re-initiated on Sotalol Hydrochloride Tablets (AF) should be placed for a minimum of three days (on their maintenance dose) in a facility that can provide cardiac resuscitation, continuous electrocardiographic monitoring and calculations of creatinine clearance. (nih.gov)
Atrial fibrillation (AF) is the most prevalent arrhythmia encountered in clinical practice (suffers about 1 % of the adult population) 1,2 and people who suffer from it, especially those aged more than 55 years, will constantly be increasing 3 . (hippokratia.gr)
CARDIAC  Cardiac arrhythmia-  PSVT  ATRIL FLUTTER  ATRIAL FIBRILLATION  AND VENTRICULAR TACHY-CARDIA can be treated by giving anti-arrhythmic drugs to mother orally or by trans-placental route. (slideshare.net)
demonstrate the ability to discuss the diagnosis, investigations, therapies and long term prognosis related to the specific arrhythmia problem with the patient and family 3. (aboutdrugspdf.com)
Dofetilide is a class III antiarrhythmic agent approved by the Food and Drug Administration for the conversion of atrial fibrillation and atrial flutter and maintenance of sinus rhythm in symptomatic patients with persistent arrhythmia. (psu.edu)
The pharmacokinetics of CORVERT Injection in patients with atrial flutter or atrial fibrillation are similar regardless of the type of arrhythmia, patient age, sex, or the concomitant use of digoxin, calcium channel blockers, or beta blockers. (pfizermedicalinformation.com)
6 The most common arrhythmia in patients with CHD is IART that occurs secondary to reentrant circuits in the right atrium. (aerjournal.com)
AF is a less common cause of atrial arrhythmia in CHD, but its prevalence is increasing in these patients because of improved survival to older age. (aerjournal.com)
Atrial fibrillation (AF) is the most common form of cardiac arrhythmia. (nature.com)
Atrial fibrillation is the most common type of cardiac arrhythmia, and is responsible for substantial morbidity and mortality in the general population. (nature.com)

however, direct-current cardioversion is treatment of choice when patient is hemodynamically compromised. (drugs.com)
Atrial flutter in an unstable patient should be treated immediately with synchronized cardioversion. (medscape.com)
The patient should be treated with an intravenous (IV) sedative prior to cardioversion if their condition permits. (medscape.com)
The pharmacological cardioversion of recent-onset atrial fibrillation (AF) is a challenge for the clinician. (hippokratia.gr)
The aim of the study was to compare the efficacy, the safety, and the overall cost of intravenous (iv) administration of vernakalant, which is a relatively new atrial-selective antiarrhythmic agent, versus ibutilide, in cardioversion of recent-onset AF. (hippokratia.gr)
Electrical cardioversion requires certain circumstances and presents various untoward issues (sedation, the presence of an anesthesiologist, and fasted patients for at least 6 hours) 9 , while monitoring is needed for at least 6 hours, and the patients are not allowed to drive for 24 hours 10 . (hippokratia.gr)
There is, therefore, a need for a pharmaceutical treatment and cardioversion of AF with fast-acting, effective, safe drugs, well tolerated by patients. (hippokratia.gr)
If a patient is hemodynamically unstable and/or has an excessively rapid ventricular rate you may consider an antiarrhthmic drug or synchronized DC cardioversion. (openanesthesia.org)
If synchronized DC cardioversion is utilized in a non-emergent setting, the provider must be certain that the atrial flutter is new-onset, that a patient does not have thrombosis in the heart via echo, or that the patient has been adequately anticoagulated in order to prevent a thromboembolic event. (openanesthesia.org)
Ibutilide is a good option for cardioversion of atrial fibrillation. (anesthesiaexperts.com)
When cardioversion is indicated, my approach is propofol sedation followed by electrical cardioversion, reserving ibutilide for patients who prefer not to undergo sedation or electrical cardioversion. (anesthesiaexperts.com)
The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM), Rate Conrol versus Electrical Cardioversion for Persistent Atrial Fibrillation (RACE), Pharmacological Intervention in Atrial Fibrillation (PIAF), Strategies of Treatment of Atrial Fibrillation (STAF) and How to Treat Chronic Atrial Fibrillation (HOT-CAFÉ) studies have been unable to show conclusively the superiority of one strategy over the other. (ecrjournal.com)

Preoperative descriptors associated with an increased prevalence of atrial tachyarrhythmias were age 70 years or older (p less than .02), mitral regurgitation (p less than .002), history of paroxysmal atrial fibrillation (p less than .03), or antiarrhythmic therapy (p less than .006), diabetes mellitus (p less than .01), and elevated pulmonary systolic, mean, and capillary wedge pressures (p less than .02, p less than .007, p less than .005). (duke.edu)
Prior to the Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial, these studies were largely conducted on patients without heart failure (HF) and included patients with paroxysmal AF. (ecrjournal.com)
2,6 However, all of these aforementioned studies were largely conducted on patients without heart failure (HF) and included patients with paroxysmal AF. (ecrjournal.com)
1 ] The overall freedom from AF is dependent on the duration of AF, with success rates ranging between 75% and 90% in patients with paroxysmal AF. (jafib.com)

Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. (wikipedia.org)
The isthmus of tissue responsible for atrial flutter is seen anterior to the coronary sinus (CS) orifice. (medscape.com)
Intravenous dofetilide can convert sustained atrial fibrillation or flutter to sinus rhythm. (qxmd.com)
Carotid sinus massage can increase AV block and better expose the typical flutter waves. (msdmanuals.com)
Nowadays, flecainide is recommended as one of the first line therapies for pharmacological conversion as well as maintenance of sinus rhythm in patients with atrial fibrillation and/or supraventricular tachycardias. (wjgnet.com)
In addition, endocardial pacemaker leads can be inserted if the patient has sinus node dysfunction. (medscape.com)
Because of its selective class III antiarrhythmic effect, dofetilide has no effect on atrioventricular conduction or sinus node function. (bmj.com)
Ten (16%) and 4 (7%) patients in the HCM and control groups, respectively, were in sinus rhythm at the time of TEE identifying the LA thrombus (p = 0.13). (bvsalud.org)
Ibutilide , a class III antiarrhythmic (Corvert, 1 mg in 10 mL saline infused slowly over 10 minutes) is effective in converting new-onset atrial flutter patients to normal sinus rhythm 90% of the time. (openanesthesia.org)
Amiodarone (150 mg IV loading dose infused over 10 minutes, followed by 1 mg/min infusion for 6 hours, a 0.5-mg/min infusion for 18 hours, and then a reduced IV dose or oral dose) is also effective in converting atrial flutter to normal sinus ryhthm. (openanesthesia.org)
There appear to be specific advantages of sinus rhythm in patients who have AF and HF. (ecrjournal.com)
These might include a salutary effect of sinus rhythm due to at least three factors: regularisation of the rhythm, physiological rate control and restoration of atrial contribution to cardiac output. (ecrjournal.com)
For decades, conventional wisdom suggested that sinus rhythm was preferred over rate control in the treatment of patients with atrial fibrillation (AF). (ecrjournal.com)
Maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter [AF/AFl]) in patients with AF/AFl lasting more than 1 wk, and who have been converted to normal sinus rhythm. (mhmedical.com)
For the conversion of atrial fibrillation and atrial flutter to normal sinus rhythm. (mhmedical.com)

Because the AV node cannot conduct at the same rate as the atrial activity, some form of conduction block is often seen, typically 2:1 (most common), 3:1, or 4:1. (medscape.com)
Atrial flutter may be perceived as a regular or irregular palpitation, the latter suggesting variable atrioventricular (AV) conduction. (medscape.com)
The flutter may be associated with syncope , severe presyncope, or chest pain, suggesting either periods of 1:1 conduction ratio or associated ventricular dysfunction. (medscape.com)
Physical examination in patients with atrial flutter should assess the likely conduction ratio and rate of flutter and assess for signs of associated ventricular dysfunction or heart failure. (medscape.com)
In intact animals it slows heart rate, decreases AV nodal conduction and increases the refractory periods of atrial and ventricular muscle and conduction tissue. (nih.gov)
Interrogation of the two-chamber ICD, which was very likely implanted unjustified in a peripheral clinic before, revealed atrial flutter with 2:1 AV conduction. (deepdyve.com)
be able to describe the basic mechanisms involved in the pathogenesis of disorders of impulse formation, impulse conduction and cardiac tachyarrhythmias including SVT, atrial fibrillation/flutter, ventricular tachyarrhythmias 4. (aboutdrugspdf.com)
In terms of its antiarrhythmic effects, digoxin slows down the conduction of electrical impulses through the atrioventricular (AV) node. (pharmacologymentor.com)
In summary, while digoxin is primarily used for heart failure, its ability to slow down AV nodal conduction makes it useful as an antiarrhythmic agent in specific cases. (pharmacologymentor.com)
As emphasized in ECG Blog #137 - the most common ventricular response to untreated atrial flutter is with 2:1 AV conduction. (blogspot.com)
At first glance, the rhythm in Figure-1 appears to be atrial flutter with this latter conduction ratio. (blogspot.com)
This is because with the exception of the variable conduction variant of flutter - there will usually be a readily identifiable repetitive pattern of atrial activity with respect to each QRS complex that results in a predictable conduction ratio. (blogspot.com)

Intravenous dofetilide, a class III antiarrhythmic agent, for the termination of sustained atrial fibrillation or flutter. (qxmd.com)
This study sought to determine the safety and efficacy of a single bolus of intravenous dofetilide, a pure class III antiarrhythmic agent, for the termination of sustained atrial fibrillation or flutter. (qxmd.com)

This finding also adds to the antiarrhythmic medical options for atrial flutter. (medscape.com)

Treatment of atrial flutter focuses on ventricular rate control, rhythm control, and prevention of thromboembolism. (msdmanuals.com)
Initial treatment of atrial flutter targets the rate control (which is frequently ~150 BPM). (openanesthesia.org)

NEW YORK (Reuters Health) - For conversion of recent-onset atrial fibrillation, vernakalant acted more rapidly and was more effective than amiodarone in an international study. (thedoctorschannel.com)
Some experts recommend revascularization and β-blockade followed by IV antiarrhythmic drugs, such as procainamide or amiodarone, for patients with recurrent or incessant polymorphic VT due to acute myocardial ischemia. (drugs.com)
Value of entrainment mapping in determining the isthmus-dependent nature of atrial flutter in the presence of amiodarone. (univ-brest.fr)
METHODS AND RESULTS: The study consisted of 83 patients with isthmus-dependent atrial flutter: 52 were taking amiodarone at the time of RFA (group 1) and 31 were in a drug-free state (group 2). (univ-brest.fr)
My Cardiologist wants to try me on Amiodarone if Digoxin doesn't work, think this is a similar antiarrhythmic. (patient.info)
1 , 2 The most common class III antiarrhythmic agents (amiodarone and sotalol) are effective but also cause undesirable side effects. (bmj.com)
M J Chapman, J L Moran, M S O'Fathartaigh, A R Peisach, D N Cunningham Management of atrial tachyarrhythmias in the critically ill: a comparison of intravenous procainamide and amiodarone. (openanesthesia.org)
We are not told if this patient is taking an antiarrhythmic agent ( such as flecainide, amiodarone, sotalol, etc. ) that might slow the atrial rate of flutter. (blogspot.com)

This finding potentially represents an important advance in the pharmacologic termination of atrial flutter. (qxmd.com)
A similar response may follow pharmacologic AV nodal blockade (eg, with adenosine ), but such therapy does not terminate atrial flutter. (msdmanuals.com)
Pharmacologic rate control is more difficult to achieve in atrial flutter than in atrial fibrillation. (msdmanuals.com)

Dofetilide is used to treat an irregular heartbeat (including atrial fibrillation or atrial flutter). (medlineplus.gov)
Atrial Fibrillation Atrial fibrillation is a rapid, irregularly irregular atrial rhythm. (msdmanuals.com)
This block may also be variable and cause atrial flutter to appear as an irregular rhythm. (medscape.com)
It is also used to treat certain fast/irregular heartbeats (atrial fibrillation/flutter) in patients with severe symptoms such as weakness and shortness of breath. (hellohippo.com)
At Rush, doctors determined she had an irregular heartbeat called atrial fibrillation . (rush.edu)

Treatment with intravenous ibutilide fumarate for acute termination of recent onset atrial flutter/fibrillation was evaluated in 466 patients participating in two randomized, double-blind, placebo-controlled clinical trials. (pfizermedicalinformation.com)

This information may guide the design of a treatment plan, particularly in patients with repaired congenital heart disease. (medscape.com)
In patients with congenital heart disease who have undergone surgery, episodes of atrial flutter have been shown to increase in frequency over time. (medscape.com)
In patients who have undergone surgery for congenital heart disease, new onset of atrial arrhythmias such as atrial flutter may indicate elevated right atrial pressure and, thus, the need for surgery (eg, conduit obstruction in a patient with a Rastelli-type surgery). (medscape.com)

See Atrial Flutter and Pediatric Atrial Flutter for complete information on these topics. (medscape.com)

Adverse effects of beta blocker therapy can lead to fatigue, bronchospasm, depression, impotence, and attenuation of hypoglycemic symptoms in diabetic patients and worsening of congestive heart failure. (pharmacology2000.com)

Clinical reports have shown that dofetilide is effective in the treatment of supraventricular tachyarrhythmias, such as atrial fibrillation and atrial flutter. (bmj.com)
Patients with suspected supraventricular or ventricular tachyarrhythmias, or both, were referred for a routine electrophysiological evaluation. (bmj.com)
Scholars@Duke publication: Clinical correlates of atrial tachyarrhythmias after valve replacement for aortic stenosis. (duke.edu)
One hundred eighteen consecutive patients undergoing valve replacement for aortic stenosis were analyzed to determine the incidence of and predisposing factors to postoperative atrial tachyarrhythmias. (duke.edu)
One of the most important causes of morbidity in patients with CHD is the development of cardiac arrhythmias, in particular tachyarrhythmias. (aerjournal.com)

General treatment goals for symptomatic atrial flutter are similar to those for atrial fibrillation. (medscape.com)
Rare and minimally symptomatic self-terminating episodes of atrial flutter are likely to require less treatment. (medscape.com)

At the time of this update, there is no consensus on the optimal management of atrial flutter in the emergency department, due to a lack of robust evidence, as well as a wide variation in typical management. (medscape.com)
In the treatment and management of atrial fibrillation (AF), the debate over 'rate versus rhythm' has largely been answered by several large randomised prospective clinical trials that have shown no distinct advantage for one strategy over the other in terms of clinical outcomes. (ecrjournal.com)

The setting and associated features of atrial flutter are an important aspect of the assessment of atrial flutter. (medscape.com)

Ibutilide's unique mechanism works by an activation of a specific inward sodium current, thus producing its therapeutic response in which a prolonged action potential increases myocytes' cardiac refractoriness in case of atrial fibrillation and flutter. (wikipedia.org)
Due to its narrow therapeutic window, patients on digoxin are closely monitored. (pharmacologymentor.com)
Figure 2: Molecular basis for atrial ionic remodelling and therapeutic opportunities. (nature.com)

Effective for rapid termination of atrial fibrillation in patients with minimal structural heart disease . (pharmacologymentor.com)

It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells. (wikipedia.org)
Additionally, it is effective as an antiarrhythmic agent for the management of ischemic and myocardial infarction-related ventricular arrhythmias. (pipelinemedical.com)
Drug trials showed neutral mortality in post-myocardial infarction patients and those with heart failure. (psu.edu)

If the ventricular response is rapid, atrial flutter may cause significant morbidity secondary to hemodynamic deterioration due to low cardiac output . (medscape.com)
In favor of AFlutter - is regular and rapid atrial activity with a peaked upward deflection in this right-sided MCL-1 monitoring lead. (blogspot.com)

120ms) is commonly found in trained athletes but care is needed not to miss underlying pathology such as an atrial septal defect, brugada syndrome or arrhythmogenic right ventricular cardiomyopathy (see below) ( 1 ). (escardio.org)

K A Ellenbogen, B S Stambler, M A Wood, P T Sager, R C Wesley, M C Meissner, R G Zoble, L K Wakefield, K T Perry, J T Vanderlugt Efficacy of intravenous ibutilide for rapid termination of atrial fibrillation and atrial flutter: a dose-response study. (openanesthesia.org)

Ibutilide, like other class III antiarrhythmic drugs, blocks delayed rectified potassium current. (wikipedia.org)
Like other antiarrhythmics, ibutilide can lead to abnormal heart rhythms due to its ability to prolong the QT interval, which can lead to the potentially fatal abnormal heart rhythm known as torsades de pointes. (wikipedia.org)
Ibutilide successfully cardioverted 55% of patients within 4 hours in a multicenter retrospective cohort study. (anesthesiaexperts.com)
If patients are given ibutilide, they must be monitored for a minimum of 4 hours if the QTc interval remains prolonged. (anesthesiaexperts.com)
Ibutilide is also cleared rapidly and highly distributed in patients being treated for atrial flutter or atrial fibrillation. (pfizermedicalinformation.com)

The Class III electrophysiological effects in man include prolongation of the atrial and ventricular monophasic action potentials, and effective refractory period prolongation of atrial muscle, ventricular muscle, and atrio-ventricular accessory pathways (where present) in both the anterograde and retrograde directions. (nih.gov)
These effects lead to prolongation of atrial and ventricular action potential duration and refractoriness, the predominant electrophysiologic properties of CORVERT in humans that are thought to be the basis for its antiarrhythmic effect. (pfizermedicalinformation.com)

Reserve for suppression and prevention of documented life-threatening ventricular arrhythmias in carefully selected patients in whom the benefits of procainamide therapy outweigh the possible risks. (drugs.com)
Beta blockers and CCB are effective in prophylactic prevention of atrial flutter after postoperative thoracic or cardiac surgery. (openanesthesia.org)
Prevention of atrial fibrillation: report from a National Heart, Lung, and Blood Institute workshop. (nature.com)
This study dealt with oral anticoagulants (OAC) for stroke prevention in patients with AF . (medscape.com)

Atrial flutter is a rapid regular atrial rhythm due to an atrial macroreentrant circuit. (msdmanuals.com)
We have labeled Figure-1 by adding red arrows for the regular atrial activity. (blogspot.com)

In the modern era, the use of digoxin for arrhythmias has declined due to the development of other antiarrhythmic drugs that are more effective and have better safety profiles. (pharmacologymentor.com)
Why is it important to know if this patient is on Digoxin? (blogspot.com)

Episodes of atrial flutter may be associated with low cardiac output, brain and other end-organ injury, and sudden or subacute death. (medscape.com)
But despite aggressive medical therapy with anti-arrhythmic drugs, Laura continued to experience episodes of atrial fibrillation and required multiple cardioversions to help reset her heart back to normal rhythm," Sharma says. (rush.edu)

Given the left sided location, the treating physicians decided to pursue medical management with beta blockers and a class Ic antiarrhythmic. (acc.org)
Flecainide acetate is a class IC antiarrhythmic agent and its clinical efficacy has been confirmed by the results of several clinical trials. (wjgnet.com)

9 , 10 Studies have shown that dofetilide prolongs both atrial and ventricular monophasic action potential durations and increases atrial and ventricular effective and functional refractory periods. (bmj.com)

Note negative sawtooth pattern of flutter waves in leads II, III, and aVF. (medscape.com)
That said, the atrial rate of 230/minute is a bit below the usual atrial rate range for untreated atrial flutter ( of 250-350/minute ) - and, the expected "sawtooth" pattern of atrial flutter is missing in this lead. (blogspot.com)

Adenosine is antiarrhythmic agent that is widely used for the investigation and management of both narrow complex and, less often, broad complex tachycardias. (pharmacologymentor.com)

Signs and symptoms in patients with atrial flutter typically reflect decreased cardiac output as a result of the rapid ventricular rate. (medscape.com)
Hypotension: Not recommended for patients for whom vasodilating agents are not appropriate, or other conditions in which cardiac output is dependent upon venous return, or for patients suspected to have low cardiac filling pressures. (nih.gov)
A study of hemodynamic function in patients with ejection fractions both above and below 35% showed no clinically significant effects on cardiac output, mean pulmonary arterial pressure, or pulmonary capillary wedge pressure at doses of CORVERT up to 0.03 mg/kg. (pfizermedicalinformation.com)

Dofetilide is well tolerated and a good choice for patients with acceptable renal function and a normal QT interval, especially if atrioventricular nodal blockade needs to be avoided. (psu.edu)
Patients with chronic bifascicular block (BFB) can progress to advanced atrioventricular block (AVB), especially when syncope or a prolonged HV interval is present. (revespcardiol.org)

Ninety-one patients with sustained atrial fibrillation (75 patients) or flutter (16 patients) were entered into a double-blind, randomized multicenter study of one of two doses of dofetilide (4 or 8 micrograms/kg body weight) or placebo. (qxmd.com)
It is important to read the patient information provided to you every time you begin therapy with dofetilide. (medlineplus.gov)
Dofetilide increased the atrial and ventricular effective refractory periods, as well as the antegrade and retrograde effective refractory period of the accessory pathway. (bmj.com)
Dofetilide is a novel class III antiarrhythmic agent that produces potent and selective blockade of the rapidly activating component of the delayed rectifier current, I kr . (bmj.com)

However, the influence of antiarrhythmic drugs on the method's value is not clearly established. (univ-brest.fr)
This Review focuses on the mechanistic rationale for the development of new anti-atrial fibrillation drugs, on the molecular and structural motifs that they target and on the results obtained so far in experimental and clinical studies. (nature.com)

In addition, the risk for thromboembolism with conversion of AF is related to the length of time a patient is in AF, not whether the patient is chemically or electrically converted. (anesthesiaexperts.com)

be able to initiate chronic prophylactic antiarrhythmic drug therapy for the management of SVT, atrial fibrillation/flutter or VT and to establish long term goals of therapy and follow-up requirements 26. (aboutdrugspdf.com)
Anticipation of atrial arrhythmias in patients with specific clinical descriptors may be used to guide prophylactic therapy. (duke.edu)
It is possible that other variables could help identify patients who would benefit from prophylactic pacemaker implantation. (revespcardiol.org)

because of higher risk of toxicity and proarrhythmic effects, antiarrhythmic agents generally reserved for patients who do not respond to or cannot be treated with AV nodal blocking agents (β-adrenergic blocking agents, verapamil, diltiazem). (drugs.com)

It is in a class of medications called antiarrhythmics. (medlineplus.gov)
Atrial rates are generally between 240 and 360 beats per minute (bpm) without medications. (medscape.com)

The diagnosis of atrial flutter is by electrocardiography (ECG). (msdmanuals.com)
In all patients, the anticoagulation strategy was modified after the LA thrombus diagnosis. (bvsalud.org)

Anatomy16

Organisms2

Diseases25

Chemicals and Drugs26

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Phenomena and Processes7

Disciplines and Occupations1

Information Science1

Health Care4

Tachycardia42

Ablation30

Left atrial4

Arrhythmia15

Cardioversion12

Paroxysmal4

Sinus15

Conduction12

Sustained atrial fibrillation or flutter2

Options for atrial flutter1

Treatment of Atrial Flutter2

Amiodarone8

Pharmacologic3

Irregular5

Recent onset1

Congenital heart d3

Pediatric Atrial Flutter1

Congestive heart f1

Tachyarrhythmias5

Symptomatic2

Management of atrial2

Assessment of atrial1

Therapeutic3

Fibrillation in patients1

Myocardial3

Rapid atrial2

Brugada Syndrome1

Termination1

Ibutilide5

Prolongation of atrial2

Prevention4

Regular atrial2

Digoxin2

Episodes2

Class Ic antiarrhythmic2

Ventricular monophasic action1

Sawtooth2

Adenosine1

Cardiac output3

Atrioventricular2

Dofetilide4

Drugs2

Thromboembolism1

Prophylactic3

Nodal1

Medications2

Diagnosis2