Proto-Oncogene Proteins c-bcl-2Apoptosisbcl-X ProteinMyeloid Cell Leukemia Sequence 1 Proteinbcl-2-Associated X ProteinInhibitor of Apoptosis ProteinsCaspasesApoptosis Regulatory ProteinsCaspase 3Cell SurvivalCASP8 and FADD-Like Apoptosis Regulating ProteinX-Linked Inhibitor of Apoptosis Proteinbcl-2 Homologous Antagonist-Killer ProteinGenes, bcl-2Cell Line, TumorCaspase InhibitorsNitrophenolsSignal TransductionMitochondriaProto-Oncogene Proteinsbcl-Associated Death ProteinNeoplasm ProteinsCytochromes cDown-RegulationCaspase 9Caspase 8GossypolIn Situ Nick-End LabelingUp-RegulationNF-kappa BBlotting, WesternDNA FragmentationRNA, Small InterferingTumor Cells, CulturedEnzyme ActivationAntineoplastic AgentsCell DeathAntigens, CD95Proto-Oncogene Proteins c-aktCells, CulturedBiphenyl CompoundsDrug Resistance, NeoplasmBH3 Interacting Domain Death Agonist ProteinReceptors, Death DomainTNF-Related Apoptosis-Inducing LigandTransfectionCell LineMicrotubule-Associated ProteinsPhosphorylationMembrane ProteinsCell ProliferationFlow CytometryPoly(ADP-ribose) PolymerasesLeukemia, Lymphocytic, Chronic, B-CellGene Expression Regulation, NeoplasticTumor Suppressor Protein p53Phosphatidylinositol 3-KinasesIntracellular Signaling Peptides and ProteinsDrug SynergismStaurosporinePiperazinesSulfonamidesCarrier ProteinsJurkat CellsTumor Necrosis Factor-alphaXenograft Model Antitumor AssaysFas Ligand ProteinMitochondrial MembranesAntineoplastic Agents, PhytogenicRNA, MessengerDose-Response Relationship, DrugDeath Domain Receptor Signaling Adaptor ProteinsImmunoblottingEnzyme InhibitorsReverse Transcriptase Polymerase Chain ReactionProtein-Serine-Threonine KinasesMice, Inbred C57BLGene Expression RegulationMice, TransgenicFas-Associated Death Domain ProteinSTAT3 Transcription FactorAmino Acid Chloromethyl KetonesProteinsCysteine Proteinase InhibitorsReactive Oxygen SpeciesHeLa CellsDrug Screening Assays, AntitumorMice, KnockoutCell CycleCaspase 7Annexin A5FlavonoidsMembrane Potential, MitochondrialDNA-Binding ProteinsRNA InterferenceCell DivisionMitogen-Activated Protein KinasesTime FactorsHL-60 CellsProtein Binding