Anti beta 2 glycoprotein beta 2 glycoprotein i. Medical search. Frequent questions

In light of the fact that lupus anticoagulants, a type of antiphospholipid antibody, have similar anticoagulant properties, the relationship of beta 2GPI to lupus anticoagulant activity was investigated. (jci.org)
The Eagle Biosciences Anti-beta 2 GP-I ELISA Assay Kit is used for the quantitative determination of IgG or IgM antibodies to ß2 glycoprotein-I (beta2 GP-I) in human serum or plasma for the diagnosis of anti-phospholipid antibody syndrome (APAS). (eaglebio.com)
In contrast, antibodies to combinations of phospholipids and serum proteins (eg, β 2-glycoprotein I [β 2-GPI] or prothrombin) are more likely associated with the vasculopathic events of antiphospholipid antibody syndrome (APS). (medscape.com)
Human IgG antibody Laboratories manufactures the tgf-beta 1 elisa kit reagents distributed by Genprice. (aabioetica.org)
Igg Antibody Laboratories manufactures the beta 2 glycoprotein 1 igg antibody anticardiolipin igg reagents distributed by Genprice. (nfkb-p65.info)
Description: A competitive ELISA for quantitative measurement of Rat Î²2 Glycoprotein 1 antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. (nfkb-p65.info)
Description: Quantitative sandwich ELISA for measuring Mouse Anti-cardiolipin antibody IgG (ACA-IgG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. (nfkb-p65.info)
Beta-2 Glycoprotein 1 Antibody is an autoantibody which is associated with inappropriate clotting of blood. (areyouhealthy.in)
Beta-2 Glycoprotein antibody is considered as one of the fundamental autoantibodies known as antiphospholipid antibodies. (areyouhealthy.in)
The biosensor is a switchable, caged luciferase-receptor-binding domain (RBD) construct that detects serum-antibody interference with the binding of virus RBD to angiotensin-converting enzyme 2 (ACE-2) as a proxy for neutralization. (nature.com)
With the availability of coronavirus disease 2019 (COVID-19) vaccines, the rise of more transmissible and pathogenic virus mutants 1 and known time-dependent declines in immunity following infection 2 , there is a need to determine the degree of serological antibody protection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). (nature.com)
Knowledge of individual immunity to SARS-CoV-2 is useful not only to determine personal actions but also to guide early therapy of patients and evaluate the efficacy of antibody treatment and vaccines over time against emerging viral variants of concern (VOCs) 3 . (nature.com)
Serological antibody tests (ideally home-based diagnostics) are critical to evaluate the response to vaccination and viral infection 2 . (nature.com)
Recently developed cell-free tools can measure antibody titers but cannot necessarily evaluate neutralization, and none of the currently available tools have estimated neutralization activity against the emerging set of SARS-CoV-2 VOCs 8 . (nature.com)
We aimed to develop a sensor technology that can quantitatively measure nAb responses against different isolates of SARS-CoV-2, be adapted for an all-in-solution multiwell format and provide rapid results in 1 hour, which is faster than established ELISA assays measuring SARS-CoV-2 antibody titer (~6 hours) or cell-based neutralization assays (~one to several days). (nature.com)
To achieve this goal, we designed an assay that focuses on antibodies competing with RBD:ACE-2 interactions as a proxy for antibody neutralization 8 (Fig. 1a,b ). (nature.com)
Objectives Evaluating the effect of repeated FTC on anticardiolipin (aCL) IgM/IgG and anti\beta\2 glycoprotein 1 (a2GPI) IgM/IgG antibody GW 542573X titer. (nanoker-society.org)
The OX-119 monoclonal antibody specifically recognizes Signal-regulatory protein gamma (SIRP-gamma or SIRPγ) which is also known as CD172g or Signal-regulatory protein beta 2 (SIRP-beta-2 or SIRPβ2). (bdbiosciences.com)
What is the advantage of an assay for anti-phospholipid antibody cofactors over an assay for the antibody itself? (diapharma.com)
What is the role of Beta 2 Glycoprotein 1 (B2GP1) in anti-phospholipid antibody binding? (diapharma.com)
Anti-beta-2-glycoprotein antibody is more closely associated with clinical features of the antiphospholipid antibody syndrome than the presence of anticardiolipin antibodies. (clinlabnavigator.com)
2000) Inhibition of in vivo neutrophil transmigration by a novel humanized anti-CD11/CD18 monoclonal antibody. (guidetopharmacology.org)
Anti-phospholipid antibodies (aPL) are a specific type of antibody found often in women and men with autoimmune issues, such as Lupus erythematosus. (kreynoldsacupuncture.com)
CONCLUSIONS: This study suggests that the positive association between physical activity and greater antibody responses seen in immunocompromised individuals following vaccination is overridden by previous SARS-CoV-2 infection, and does not extend to natural immunity. (bvsalud.org)
Thrombocytopenia, low complement, positive anti-dsDNA, and medium-high titer antiphospholipid antibody (aPL) are the main manifestations of ANA-negative SLE. (archivesofrheumatology.org)
Serum anticardiolipin antibody testing (CLPMG / Phospholipid [Cardiolipin] Antibodies, IgG and IgM, Serum) and anti-beta-2 glycoprotein I (B2GMG / Beta-2 Glycoprotein 1 Antibodies, IgG and IgM, Serum) antibody testing should also be performed in conjunction with coagulation-based testing for LA to enhance detection of different types of antiphospholipid antibodies. (mayocliniclabs.com)
PVDF membrane was probed with 0.25 µg/mL of Sheep Anti-Mouse/Rat Apolipoprotein H/ApoH Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6575) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016 ). (rndsystems.com)
Description: A competitive ELISA for quantitative measurement of Human Anti centriole and centrosome antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. (cdna-clone.com)
This brings me to my most potentially revolutionary abstract of the conference, which evaluated CAR-T directed against anti-beta 2 glycoprotein 1 expressing B cells in antiphospholipid antibody syndrome (APLS). (figure1.com)
This is a much more plausible role for CAR-T, because patients with beta-2 glycoprotein APLS 1) have a specific antibody driving pathology, which is created by 2) a specific subset of B cells that 3) are often refractory to conventional therapies. (figure1.com)
Patients with a history of 2 or more clinical miscarriages (CM) underwent an RPL work-up recommended by the American Society for Reproductive Medicine, including blood work for parental karyotypes, anti-phospholipid antibodies (anti-cardiolipin antibody, lupus anticoagulant and beta-2-glycoprotein) and a uterine cavity evaluation prior to attempting conception. (biomedcentral.com)

Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2-glycoprotein I. (jci.org)
IgG from patients with autoimmune diseases or syphilis were tested for anticardiolipin reactivity and lupus anticoagulant activity in the presence and absence of beta 2GPI. (jci.org)
These data demonstrate that antiphospholipid autoantibodies exert lupus anticoagulant activity via an interaction with beta 2GPI. (jci.org)
Anti-β2-GP1 antibodies are strongly associated with thrombotic forms of lupus. (wikipedia.org)
Evaluate for lupus anticoagulant and anti-beta-2 glycoprotein I antibodies as well. (medscape.com)
The three main cornerstone antibodies are anticardiolipin (aCL) IgM/IgG, anti\beta\2 glycoprotein 1 antibodies (a2GPI) IgM/IgG, and lupus anticoagulant (LAC). (nanoker-society.org)
Anti beta 2 glycoprotein IG A antibodies independently and differentially contribute to thrombotic risk in systemic lupus erythematosus above and beyond anti-cardiolipin and lupus anticoagulant, from a contemporary multiethnic patient cohort. (uclahealth.org)
Given with anti-coagulant blood testing for lupus. (dobratechnologia.pl)
Hughes Syndrome/Antiphospholipid syndrome (APS) is a systemic autoimmune, hypercoagulable, thrombo inflammatory, and thrombosis and/or pregnancy complications syndrome caused by the persistent presence of antiphospholipid antibodies (APL) in plasma of patients with vascular thrombosis and/or pregnancy morbidity along with persistent anti-phospholipid antibodies (APLA), including lupus anticoagulant (LA), anti-β2-glycoprotein I (anti-β2GPI) and/or anti-cardiolipin (ACL) antibodies. (endinglines.com)
To investigate associations with baseline and prospective 5-year changes in echocardiographic parameters, we performed multivariate regression analyses of SLE-related baseline variables (clinical disease activity, lupus nephritis, chronic kidney disease, anti-cardiolipin and/or anti-beta-2 glycoprotein I antibodies, and lupus anticoagulant (LAC)) and adjusted for traditional risk factors. (ox.ac.uk)

1987) Heterogeneous mutations in the beta subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency. (guidetopharmacology.org)
Diagnosis of leukocyte adhesion deficiency is by detecting absence or severe deficiency of adhesive glycoproteins on the surface of WBCs using monoclonal antibodies (eg, anti-CD11, anti-CD18) and flow cytometry. (msdmanuals.com)

As expected, anti-cardiolipin reactivity associated with autoimmune disease was beta 2GPI dependent. (jci.org)
In contrast, IgG from a patient with syphilis recognized cardiolipin alone and binding was inhibited by beta 2GPI. (jci.org)
Positivity for anti-cardiolipin antibodies in diagnostic tests for autoimmune antiphospholipid syndrome requires the presence of β2-GP1in the cardiolipin extract. (wikipedia.org)
Anti-cardiolipin antibodies are by definition a major criterion for a diagnosis of APS. (dobratechnologia.pl)
What is the clinical significance when samples test positive for the anti-cardiolipin antibodies and are negative for anti-b2GPI? (diapharma.com)
Summarize the IgG/IgM and IgA REAADS anti-cardiolipin test. (diapharma.com)
Beyond the immediate health implications, recent studies, including Dr. Kharazian's research, have raised concerns about the cross-reactivity of the spike protein with beta 2 glycoprotein and anti-cardiolipin antibodies. (holisticcharlotte.com)

MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. (thermofisher.com)
SIRPγ (CD172g) is a ~55 kDa type I transmembrane glycoprotein that is encoded by SIRPG, which belongs to the SIRPβ2 subfamily within the Ig gene superfamily. (bdbiosciences.com)

beta 2-Glycoprotein I (beta 2-GPI) is a major antigen for antiphospholipid antibodies (aPL) present in patients with antiphospholipid syndrome (APS). (elsevierpure.com)
The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long. (thermofisher.com)

It has been reported that antiphospholipid autoantibodies do not recognize phospholipid alone, but rather the plasma protein beta 2-glycoprotein I (beta 2GPI), or a beta 2GPI-phospholipid complex. (jci.org)
β2-glycoprotein 1, also known as beta-2 glycoprotein 1 and Apolipoprotein H (Apo-H), is a 38 kDa multifunctional plasma protein that in humans is encoded by the APOH gene. (wikipedia.org)
In molecular biology, the protein domain Sushi 2 is also known as the fifth protein domain of beta-2 glycoprotein 1 (β2-GP1). (wikipedia.org)
This protein domain is composed of four well-defined anti-parallel beta-strands and two short alpha-helices, as well as a long highly flexible loop. (wikipedia.org)
We designed a protein biosensor that uses thermodynamic coupling for sensitive and rapid detection of neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in serum. (nature.com)
The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein binds to the angiotensin-converting enzyme 2 (ACE-2) receptor on target cells and is the immunodominant target of neutralizing antibodies (nAbs) identified from convalescent and postvaccination plasma 3 . (nature.com)
the large (L) segment encodes viral RNA-dependent RNA polymerase, the medium (M) segment encodes glycoprotein precursor, and the small (S) segment encodes nucleocapsid protein ( 4 ). (cdc.gov)
Conversely, the transcription of COX-2 yields a 4.5-kb mRNA that encodes a 70-kd protein with roughly 70-75% homology to the COX-1 protein. (medscape.com)
Within the past 2 years, investigational peptide- and recombinant protein-based serologic assays that can more easily differentiate the antibodies to HTLV-I and HTLV-II have been developed (8,9). (cdc.gov)

Monoclonal Anti-Monkey IgG-HRP Conj. (toll-likereceptors.com)

Anti-beta 2-GPI autoantibodies derived from APS patients with episodes of arterial thrombosis were detected in ELISA, using a solid phase beta 2-GPI complex with oxLig-1. (elsevierpure.com)
The serologic detection of anti-b2GPI antibodies provides enhanced clinical sensitivity for thrombosis. (diapharma.com)
Approximately 2 million people in the United States die each year from an arterial or venous thrombosis. (clinlabnavigator.com)
A patient with the factor V Leiden mutation (1st hit) who uses oral contraceptives (2nd hit) greatly increases their risk of thrombosis by combining the 2 risk factors. (clinlabnavigator.com)

The Anti-Beta 2 GP1 ELISA is an enzyme immunoassay for the quantitative determination of IgG or IgM antibodies to ß2 glycoprotein-I in human serum or plasma. (eaglebio.com)
The Tgf-Beta 1 Elisa Kit reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (aabioetica.org)
Measure serum ALT, AST, and bilirubin prior to initiation of eltrombopag, every 2 weeks during the dose adjustment phase, and monthly following establishment of a stable dose. (salesandmarketingnetwork.com)
Most autoimmune anti-phospholipid antibodies require the serum cofactor b2GPI for optimal binding. (diapharma.com)

these glycoproteins facilitate cellular interactions, cell attachment to blood vessel walls, cell movement, and interaction with complement fragments. (msdmanuals.com)

Apolipoprotein H (ApoH), also known as beta 2‑Glycoprotein I/ beta 2-GPI, is a variably glycosylated member of the complement control superfamily of proteins with a molecular weight of aproximately 50 kDa (1, 2). (rndsystems.com)

Autoimmune antiphospholipid antibodies prolonged the dilute Russell viper venom time of normal plasma, but had no effect on beta 2GPI-depleted plasma. (jci.org)
Tests include APTT, PT, mixing studies, hexagonal phase phospholipid test, dilute Russell viper venom time, thrombin time, anticardiolipin IgG and IgM antibodies and anti-beta-2-glycoprotein I IgG and IgM antibodies. (clinlabnavigator.com)

Binding of liposomes containing oxLig-1 to macrophages were significantly enhanced in the presence of both beta 2-GPI and an anti-beta 2-GPI autoantibody derived from (NZW x BXSB) F1 mouse, an animal APS model, or from APS patients. (elsevierpure.com)
Although significance and pathological relevance of phospholipid anti-bodies are not completely revealed yet, the detection of several autoantibody specificities is usually applied to the differential diagnosis and follow-up of systemic rheumatic inflammatory diseases. (eaglebio.com)

The extent to which immune responses to natural infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and immunization with vaccines protect against variants of concern (VOC) is of increasing importance. (nature.com)

The effect of triple therapy on the mortality of catastrophic anti-phospholipid syndrome patients. (medscape.com)
2,3,4 Patients with paediatric chronic ITP are at a risk of severe bleeding. (gsk.com)
Immune (idiopathic) thrombocytopenic purpura (ITP) - characterized by a low platelet count - affects as many as 5 in 100,000 children each year.1 While many children with ITP do not require treatment and/or their disease resolves, up to 30 percent of patients experience persistent disease at 12 months and are diagnosed with cITP.2, 3,4 Patients with pediatric cITP are at a high risk of severe bleeding. (salesandmarketingnetwork.com)
PETIT2 was 2-part, double-blind, randomized placebo-controlled and open-label study to investigate the efficacy, safety and tolerability of eltrombopag in pediatric patients with previously treated cITP. (salesandmarketingnetwork.com)
This pain is generally exacerbated with extraocular movements, and occurs in the vast majority of patients with typical ON.2 Patients with features atypical of ON, such as those that suggest other etiologies (i.e. abrupt onset of vision loss suggestive of a vascular etiology), warrant ophthalmology evaluation. (clevelandclinic.org)
Funduscopic examination can appear normal acutely, but disc edema can be present in approximately one-third of patients (particularly those with anterior optic neuritis).1, 2 Optic disc pallor is generally seen weeks to months following onset of typical optic neuritis. (clevelandclinic.org)
AIM: To investigate the association between physical activity and immunogenicity among SARS-CoV-2 seropositive patients with autoimmune rheumatic diseases prior to and following a 2-dose schedule of CoronaVac (Sinovac inactivated vaccine). (bvsalud.org)
In this substudy, only SARS-CoV-2 seropositive patients were included. (bvsalud.org)
It is necessary to identify complement, anti-dsDNA, and aPL in ANA-negative patients with rheumatic symptoms, particularly thrombocytopenia. (archivesofrheumatology.org)
Correlation between beta-2-glycoprotein I gene polymorphism and anti-beta-2 glycoprotein I antibodies in patients with multibacillary leprosy. (cdc.gov)
For those patients who achieved a spontaneous conception, 88% conceived within 6 months, with a median time of 2 months and range of 1-10 months. (biomedcentral.com)
In the 1990s, an outbreak of HFRS in 2 regions of European Russia (Tula and Ryazan) was serologically confirmed to be caused by DOBV, but no clinical characterization of the patients was reported ( 10 ). (cdc.gov)

One of these cofactors has been identified as ß2 glycoprotein-I (ß2 GP-I) (apolipoprotein H) (2,3). (eaglebio.com)

This test profile identifies and estimates the IgM class of beta-2 glycoprotein 1 antibodies. (areyouhealthy.in)

Anticardiolipin and Anti-Beta-2 Glycoprotein 1 Antibodies. (dobratechnologia.pl)
anticardiolipin (aCL), which has three subcomponents: lgG, lgA, lgM anti-Beta-2-glycoprotein-I (aβ 2 GPI), which has the same three subcomponents LAC The LAC is the most important of these antibodies because it confers the greatest risk for developing clinical complications. (dobratechnologia.pl)

Screening with 2 or more phospholipid-dependent coagulation tests and demonstrating prolongation of at least one. (medscape.com)

Description: Sandwich High Sensitivity ELISA kit for Quantitative Detection of activated Pig porcine TGF beta 1. (aabioetica.org)

Type 1 results from mutations in the integrin beta-2 gene ( ITGB2 ), encoding CD18 beta-2 integrins. (msdmanuals.com)
Type 2 results from mutations in the glucose diphosphate (GDP)-fucose transporter gene. (msdmanuals.com)

In vitro beta 2GPI binds to anionic phospholipids and inhibits the prothrombinase activity of procoagulant membranes. (jci.org)
[ 2 ] This is likely due to the class and concentration of phospholipids because certain studies have reported abolishing the LA effect on the aPTT when reagents rich in phosphatidyl serine are used. (medscape.com)

Unlike multiplex or ELISA assays, the HEp-2 cell substrate provides 100-150 possible autoantigens to detect ANAs with greater sensitivity than the solid phase assays. (nemours.org)

The immunofluorescence ANA assay (Antibodies, Inc) utilizes the method considered the gold standard for ANA testing by the American College of Rheumatology: detecting circulating autoantibodies reactive with nuclear antigens of HEp-2 cells. (nemours.org)

All of these observations strongly suggest that autoimmune atherogenesis linked to beta 2-GPI interaction with oxLDL and autoantibodies may be present in APS. (elsevierpure.com)
It has been shown that many anti-phospholipid antibodies may react to a neoepitope formed on the b2GPI molecule by the interaction between the phospholipid and b2GPI. (diapharma.com)

We previously reported that beta 2-GPI specifically binds to oxidized low-density lipoprotein (oxLDL). (elsevierpure.com)

This is based on evidence showing that no single test is sensitive for detecting all LA. However, the risk of false-positive results increases to an unacceptable level if more than 2 screening tests are performed. (medscape.com)
These three variants share the N501Y substitution in the receptor-binding domain (RBD) of spike glycoprotein (S), which increases the binding affinity of S with the virus's cellular receptor, angiotensin-converting enzyme 2 (ACE2) 2 (see Fig. 1 ). (nature.com)

clinical nutrition as a specialty goes here HN - 2008 BX - Nutrition FX - Diet FX - Food DH - Child Nutrition DI - 052504 MN - SP6.021.062 MS - Nutrition of children aged 2-10 years. (bvsalud.org)

Is administering one Anti-Phospholipid test sufficient for diagnosis? (diapharma.com)
Interpretation: The key mortality risk factors at the time of SjS diagnosis were positive cryoglobulins and a high systemic activity scored using the ESSDAI, conferring a 2-times increased risk of all-cause and SjS-related death. (bvsalud.org)

For example, a coagulation assay for the detection of LA and an ELISA for the detection of anti-phospholipid antibodies or cofactors like anti-CL or anti-b2GPI are recommended. (diapharma.com)

ed about warfarin and possible adverse that coronary embolism occurs in the We administered unfractionized reactions with other drugs and followed left coronary artery in 75% of cases and heparin and tirofiban (glycoprotein regularly. (who.int)

The Anti-beta 2 GP-I ELISA is for research use only and not for diagnostic procedures. (eaglebio.com)

ITGB2 is the beta component of the β2 integrins. (guidetopharmacology.org)

Beta 2GP1 Ab, Beta-2 Glycoprotein 1 Antibodies IgG, IgM, and IgAs.Immunoglobulin Isotype specific antibodies and controls are specific to the immunoglobulin heavy chains and immunoglobulin light chains. (conzort.com)

With an incidence of 1-2 per million, diagnosing aHUS requires a high index of suspicion and the exclusion of thrombotic thrombocytopenic purpura (TTP). (asn-online.org)
The Beta 2 Glycoprotein 1-IgM test helps in investigating inappropriate blood clot formation which is known as a thrombotic episode or venous thromboembolism. (areyouhealthy.in)

The bound antibodies react specifically with anti-human-IgG or IgM conjugated to horseradish peroxidase (HRP) within the next incubation period of 30 min at RT. (eaglebio.com)

It was also reported that LDL-receptor-deficient mice that were fed a chow diet and immunized with beta 2-GPI had an accelerated atherosclerosis and that beta 2-GPI was abundantly expressed within subendothelial regions and intimal-medial borders of human atherosclerotic plaques. (elsevierpure.com)
Giannakopoulos B , 2016 , 'Do Beta 2-Glycoprotein i Disulfide Bonds Protect the Human Retina in the Setting of Age-Related Macular Degeneration? (edu.au)
After washing, enzyme conjugated anti-human IgG, IgM, or IgA immunoglobulin is added, the wells are washed again, substrate added, and color development measured in a spectrophotometer at 450 nm. (diapharma.com)
In the wake of the COVID-19 pandemic, emerging research has shed light on the intricate interplay between the SARS-CoV-2 virus and the human body. (holisticcharlotte.com)
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. (conzort.com)
Hantaviruses cause 2 human zoonoses: HFRS in Asia and Europe (caused by Hantaan virus [HTNV], Seoul virus [SEOV], PUUV, and DOBV) and hantavirus (cardio)pulmonary syndrome in the Americas (caused by Sin Nombre and Andes viruses) ( 2 - 4 ). (cdc.gov)
Furthermore, using sequence analysis of human genomic DNA, researchers concluded that the amino acids important for catalysis by COX-1 are conserved and are equally important for catalysis by COX-2. (medscape.com)
Human T-lymphotropic viruses, type I (HTLV-I) and type II (HTLV-II), were the first human retroviruses discovered (1,2). (cdc.gov)
They are only distantly related to the human immunodeficiency viruses (HIV-1 and HIV-2), which belong to the lentivirus subfamily of retroviruses and which cause acquired immunodeficiency syndrome (AIDS). (cdc.gov)

The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 22: Issue 2 (Aug 2023): End-Stage Kidney Disease, is now avail. (asn-online.org)

RP-1, an anti-beta 2GPI mAb, had anticoagulant effects similar to those of autoimmune antiphospholipid antibodies. (jci.org)
These antibodies and RP-1 appear to amplify the anticoagulant effect of beta 2GPI itself. (jci.org)

Charles and colleagues reported glycoprotein IIb/IIIa inhibitors [9-11]. (who.int)
By 1964, after recognition of this basic structure, Bergstrom and colleagues successfully synthesized series 2 prostaglandins from arachidonic acid using sheep seminal fluid. (medscape.com)
Tay and colleagues then localized COX-2 to 1q25.2-q25.3 via fluorescein in situ hybridization. (medscape.com)

Anti-β2-GP1 antibodies are found in both infectious and some systemic autoimmune diseases (eg. (wikipedia.org)
Acetylsalicylic acid, thought to be due to coronary embo- in recent years, systemic thromboem- beta-blockers and intravenous heparin lism. (who.int)

El ligando es específico para el RECEPTOR 4-1BB y puede desempeñar un papel en la indución de la proliferación de los LINFOCITOS T activados de la sangre periférica. (bvsalud.org)

Anti-beta 2-glycoprotein I autoantibodies and atherosclerosis. (elsevierpure.com)
Further, a ligand specific for beta 2-GPI, oxLig-1, purified from the extracted lipids of oxLDL was identified as 7-ketocholesterol-9-carboxynonanoate (i.e., 9-oxo-9-(7-ketocholest-5-en-3 beta-yloxy) nonanoic acid) OxLig-1 was recognized by beta 2-GPI and subsequently by anti-beta 2-GPI autoantibodies. (elsevierpure.com)
Dive into the research topics of 'Anti-beta 2-glycoprotein I autoantibodies and atherosclerosis. (elsevierpure.com)

She had no risk factors for coronary artery disease in her medical history but it was learned that she had undergone a mitral valve replacement 2 years before because of rheumatic mitral stenosis and that no international normalized ratio (INR) analysis had been done in the last 6 months. (who.int)

The emergence of new lineages of SARS-CoV-2 on three continents towards the end of 2020, and their rapid expansion at the expense of the previously dominant lineages, poses significant challenges to public health 1 . (nature.com)
In early 2021, E484K had been detected first in lineage B.1.1.7 in the United Kingdom (UK) 6 and subsequently in lineages A23.1, B.1 and B.1.177, as well as in imported cases of B.1.51 and P.2 1 . (nature.com)

Anatomy5

Organisms6

Diseases4

Chemicals and Drugs69

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Phenomena and Processes28

Information Science4

Antibody31

Lupus10

Leukocyte adhesion d2

Cardiolipin7

Transmembrane2

Antigen2

Protein9

Monoclonal1

Thrombosis4

Serum4

Interactions1

APOH1

Dilute2

Autoantibody2

Severe acute respi1

Patients12

Apolipoprotein1

Identifies1

Anticardiolipin2

Phospholipid-dependent1

ELISA Kit1

Gene2

Phospholipids2

Sensitivity1

Rheumatology1

Interaction2

Binds1

Increases2

Clinical1

Diagnosis2

Cofactors1

Warfarin1

Diagnostic1

ITGB21

Isotype1

Thrombotic2

Antibodies react1

Human9

20231

Anticoagulant2

Colleagues3

Systemic2

Receptor1

Autoantibodies3

Rheumatic1

Lineages2