• After developing an immune response, B-cells from mice can be fused with immortalizing cells to form a hybridoma that produces monoclonal antibodies (Mab or MoAb). (wikipedia.org)
  • Like all QIAGEN mouse monoclonal antibodies, they are prepared under serum-free conditions, which guarantees the absence of viruses, mycoplasma and contaminating immunoglobulins. (qiagen.com)
  • For detection, QIA express mouse monoclonal antibodies are produced under conditions that guarantee the highest purity and activity. (qiagen.com)
  • How Do Anti-CD20 Monoclonal Antibodies Work? (rxlist.com)
  • Anti-CD20 monoclonal antibodies are administered as a solution (liquid) to be added to fluid and injected intravenously (into a vein). (rxlist.com)
  • Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. (abcam.com)
  • InvivoGen provides a family of Anti-Spike RBD CR3022 -derived monoclonal antibodies (mAbs) in multiple human and mouse isotypes. (invivogen.com)
  • The study was the first to show the benefits of monoclonal antibodies on tooth regeneration and provides a new therapeutic framework for a clinical problem that currently can be resolved only with implants and other artificial measures. (yahoo.com)
  • Current technologies for treatment of many lymphomas, leukemias, transplant rejection and some autoimmune disorders include monoclonal antibodies (mAb) that target and deplete B cell populations. (nationaljewish.org)
  • Chemotherapeutic agents, corticosteroids, and monoclonal antibodies are used to reduce the disease burden, and bisphosphonates are used to promote bone healing and to provide secondary prophylaxis against skeletal-related events (eg, hypercalcemia, bone fracture, spinal cord compression, need for radiation, and need for surgery). (medscape.com)
  • In this study we have profiled a panel of mouse antihuman CD40 monoclonal antibodies (MoAbs), regarding their CD40 binding affinity and epitope-specificity relative to the CD40L binding in relation to their cellular activating potential. (lu.se)
  • These antibodies have been verified by Relative expression to confirm specificity to LDHC. (thermofisher.com)
  • We perform extensive in-house testing to confirm the specificity and functionality of our anti-idiotype antibodies. (rndsystems.com)
  • GenScript MonoRab™ Rabbit Anti-VHH antibodies show ultra-high specificity for VHH-based CAR T cells. (genscript.com)
  • In certain clinical settings, false-positive anti-HCV results are rare because the majority of persons being tested have evidence of liver disease and the sensitivity and specificity of the screening assays are high. (cdc.gov)
  • This study has been conducted to assess the reliability and specificity of anti- CCP in the Sudanese as an indicator of RA. (bvsalud.org)
  • Other laboratories performing comparative analyses of licensed anti-HIV EIA test kits have found similar or slightly lower sensitivity and specificity (2-5). (cdc.gov)
  • In addition, false-positive test results are observed when nonspecific serologic reactions occur among uninfected persons who have immunologic disturbances or who have had analyses of licensed anti-HIV EIA test kits have found similar or slightly lower sensitivity and specificity (2-5). (cdc.gov)
  • IgG hepatitis E virus (HEV) antibody testing of stored sera specimens from NHANES III using the Wantai HEV-IgG ELISA assay was conducted to evaluate correlation of results with those of other IgG anti-HEV assays. (cdc.gov)
  • Further testing with the Wantai HEV-IgG ELISA assay and an in-house anti-HEV Western Blot assay was performed on a subset of 1803 of the 6000 samples. (cdc.gov)
  • WANTAI HEV-IgG ELISA is an enzyme-linked immunosorbent assay for the qualitative detection of IgG-class antibodies to hepatitis E virus in human serum or plasma. (cdc.gov)
  • WANTAI HEV-IgG ELISA employs solid phase, indirect ELISA method for detection of IgG-class antibodies to HEV (anti-HEV) in two-step incubation procedure. (cdc.gov)
  • Antibodies that detect ARMC1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry and ELISA. (thermofisher.com)
  • All of our anti-MMP antibodies are produced and validated in-house to ensure they will meet your microscopy, ELISA, and western blot needs. (southernbiotech.com)
  • Based on ELISA and flow cytometry, this antibody reacts with the heavy and light chains of rabbit IgG, and with the light chains of rabbit IgM and IgA. (licor.com)
  • Based on immunoelectrophoresis and/or ELISA, the antibody reacts with the Fc portion of dog IgG heavy chain but not with the Fab portion of dog immunoglobulins. (jacksonimmuno.com)
  • Dried blood spot samples were tested for LASV antibodies by ELISA to determine the seropositivity of participants, indicating previous exposure to LASV. (bvsalud.org)
  • The assay setup with the biotinylated antibody immobilized onto streptavidin-coated magnetic beads significantly reduced the amount of coating antibody giving identical sensitivity (50% saturation of the signal (SC(50))=0.2-0.4ng/ml) to the best result obtained with direct coating of the antibody on ELISA plates. (cdc.gov)
  • FITC (Fluorescein isothiocyanate) is the form of fluorescein used for conjugation to all of our antibodies and purified proteins, with the exception of streptavidin. (jacksonimmuno.com)
  • Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD24 Antibody, Clone M1/69, followed by a mouse anti-rat IgG2b antibody, FITC (filled histogram), or Rat IgG2b, kappa Isotype Control Antibody, Clone RTK4530 (Catalog #60077), followed by a mouse anti-rat IgG2b antibody, FITC (solid line histogram). (stemcell.com)
  • The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. (biolegend.com)
  • Testing was also performed using an in-house anti-HEV Western Blot assay. (cdc.gov)
  • In an indirect enzyme-linked immunoassay (EIA) or an immunofluorescence assay, antibody is detected using an antitarget species secondary conjugated antibody. (usgs.gov)
  • The sensitivity of the assay depends on the avidity of the binding reaction between the bound antibody and the detection antibody. (usgs.gov)
  • Using different types of anti-idiotypes allows more flexibility in assay development. (rndsystems.com)
  • The anti-idiotype antibody is tested in a bridging assay. (rndsystems.com)
  • The drug-sensitive Quantum Blue ® Anti-Infliximab assay allows for a highly specific detection of antibodies against infliximab within 15 min. (buhlmannlabs.ch)
  • the individual had the highest antibody levels, with a broad range against several variants in a previous neutralization assay. (news-medical.net)
  • Testing for anti-HCV should include use of an antibody screening assay, and for screening test-positive results, a more specific supplemental assay. (cdc.gov)
  • Magnetic bead-based phage anti-immunocomplex assay (PHAIA) for the detection of the urinary biomarker 3-phenoxybenzoic acid to assess human exposure to pyrethroid insecticides. (cdc.gov)
  • In this work we explore a new format that may help to optimize the performance of the phage anti-immunocomplex assay (PHAIA) technology. (cdc.gov)
  • Anti-glomerular basement membrane (anti-GBM) antibody disease is a rare autoimmune disorder in which circulating antibodies are directed against an antigen normally present in the GBM and alveolar basement membrane, specifically the alpha-3 chain of type IV collagen. (medscape.com)
  • In addition, anti-GBM disease has a strong positive association with the human leukocyte antigen (HLA)-DR15 haplotype, particularly the DRB1*1501 allele, which is found in more that 80% of patients with anti-GBM disease. (medscape.com)
  • During the second incubation step, these HRP-conjugated antibodies will be bound to any antigen-antibody (IgG) complexes previously formed and the unbound HRP-conjugate is then removed by washing. (cdc.gov)
  • Chromogen solutions containing Tetramethylbenzidine (TMB) and urea peroxide are added to the wells and in presence of the antigen-antibody-anti-IgG (HRP) immunocomplex, the colorless Chromogens are hydrolyzed by the bound HRP conjugate to a blue colored product. (cdc.gov)
  • Isolation of the target antigen of human anti-tubular basement membrane antibody-associated interstitial nephritis. (jci.org)
  • This recommendation is consistent with testing practices for hepatitis B surface antigen and antibody to human immunodeficiency virus (HIV), for which laboratories routinely conduct more specific reflex testing before reporting a result as positive ( 1 , 3 ). (cdc.gov)
  • These highly specific and high-affinity recombinant antibodies are suitable for bioanalysis and drug monitoring of daratumumab and its biosimilars. (the-scientist.com)
  • The new range of anti-daratumumab antibodies comprises three fully human IgG1 inhibitory antibodies with varying levels of affinity. (the-scientist.com)
  • Isolation of specific antibodies was accomplished by affinity chromatography using pooled rabbit IgG covalently linked to agarose. (licor.com)
  • Using a monoclonal anti-tubular basement membrane antibody (alpha TBM-Ab) affinity column, we isolated from collagenase-solubilized human renal tissue (HSRTA) a predominantly 48,000-mol-wt moiety (H3M-1) which is selectively recognized by antisera from two patients with alpha TBM-Ab-associated interstitial nephritis (alpha TBM disease). (jci.org)
  • Further experiments will involve the characterization of the effectiveness of Curly 14 for modulating immune disease, understanding Curly 14 binding affinity, determination of the antibody binding site and the ability to destabilize and/or desensitize B cells in huSCID and human CD79 knockin mouse models. (nationaljewish.org)
  • Some of these antibodies can detect proteins in specific grass taxa such as Triticeae (Triticeae glutens), while others react sporadically with certain species in those taxa, or over many taxonomically defined grass tribes. (wikipedia.org)
  • For the sensitivity of the three Anti·His Antibodies in detecting this panel of proteins see the figure Sensitivity of anti·His antibodies. Detection of 6xHis-tagged proteins with Anti·His Antibodies (Tetra·His Antibody in the center). A: DHFR; B: DHFR; C: thioredoxin; D: TNF-α; E: TFIIA γ ; F: chaperonin; G DNA polymerase; H: TFIIAαß; for tag location and sequences detected see table 'Proteins detected with QIA express Anti·His Antibodies'. Indicated amounts of pure 6xHis-tagged protein were applied to a nitrocellulose membrane, and detection was carried out with the Anti·His primary antibody indicated diluted 1/2000, followed by chromogenic detection with AP-conjugated rabbit anti-mouse IgG and NBT/BCIP. "> "Sensitivity of QIA express Anti·His Antibodies" ). (qiagen.com)
  • The wells are washed to remove unbound serum proteins and then, rabbit anti-human IgG antibodies (anti-IgG) conjugated to horseradish peroxidase (HRP-Conjugate) is added. (cdc.gov)
  • This antibody was tested by dot blot and and/or solid-phase adsorbed for minimal cross-reactivity with human, mouse, rat, sheep, and chicken serum proteins, but may cross-react with immunoglobulins from other species. (licor.com)
  • No antibody was detected against non-immunoglobulin serum proteins. (jacksonimmuno.com)
  • If these enzymes leak out into the bloodstream (as when thyroid cells are damaged) the immune system makes antibodies against these proteins. (medlineplus.gov)
  • Monoclonal mouse Anti·His Antibodies (5xHis antibodies and 4xHis antibodies), like the RGS·His Antibody, BSA-free, Tetra·His Antibody, BSA-free and Penta·His Antibody, BSA-free are used to detect recombinant protein carrying His tags. (qiagen.com)
  • Our anti-idiotype antibodies are specifically designed to detect the biosimilar antibody it is targeting. (rndsystems.com)
  • The anti-idiotype antibody is used to capture and detect the biosimilar. (rndsystems.com)
  • The anti-idiotype antibody is used to detect the biosimilar antibody but does not detect other irrelevant biosimilar antibodies. (rndsystems.com)
  • Tests to detect antibody to hepatitis C virus (anti-HCV) were first licensed by the Food and Drug Administration (FDA) in 1990 ( 1 ). (cdc.gov)
  • Tests to detect antibody to human immunodeficiency virus (HIV), the virus that causes acquired immunodeficiency syndrome (AIDS), were first licensed by the Food and Drug Administration (FDA) in 1985, primarily as screening tests for blood and plasma donation. (cdc.gov)
  • Profiling anti-cyclic citrullinated peptide antibodies in patients with juvenile idiopathic arthritis. (medscape.com)
  • The Anti-Spike RBD clone CR3022 is a SARS-CoV neutralizing antibody that was obtained from the screening of an antibody-phage library and converted to a human IgG1 format [1]. (invivogen.com)
  • binding of the RM4-5 antibody can be blocked by the clone GK1.5 antibody. (stemcell.com)
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD4+ T Cell Isolation Kit (Catalog #19852) and EasySep™ Mouse CD25 Regulatory T Cell Positive Selection Kit (Catalog #18782). (stemcell.com)
  • Anti-mMincle-IgG (clone 6G5) is a monoclonal rat IgG2b antibody specific for murine Mincle (mMincle). (invivogen.com)
  • As a model system we used a polyclonal antibody to 3-phenoxybenzoic acid (3-PBA) and an anti-immunocomplex phage clone bearing the cyclic peptide CFNGKDWLYC. (cdc.gov)
  • A 3-fold serial dilution of the Anti-Spike-RBD hIgG1 (red curve) or of the Anti-βGal hIgG1 control antibody (grey curve) was performed for the capture step. (invivogen.com)
  • The amount of color intensity can be measured and is proportional to the amount of antibody captured in the wells, and to the sample respectively. (cdc.gov)
  • , 2020. Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody. (invivogen.com)
  • Recognizing that USAG-1 is a bifunctional protein that antagonizes BMP and Wnt, Dr. Takahashi investigated the effects of a monoclonal antibody for USGA-1. (yahoo.com)
  • The latest VOC, Omicron, carries 37 mutations in its spike protein, most of which lie within the receptor-binding domain (RBD), the target for neutralizing antibodies (nAbs). (news-medical.net)
  • [ 1 ] Anti-RA33 positivity may also be associated with systemic lupus erythematosus and mixed connective-tissue disease. (medscape.com)
  • I am looking for goat, rabbit, or sheep anti-human Rb antibodies. (bio.net)
  • They are man-made antibody that was developed using cloning and recombinant DNA technology from human and murine (mice or rat) genes and work by inhibiting early-stage B lymphocyte activation. (rxlist.com)
  • These antibodies target ARMC1 in Human samples. (thermofisher.com)
  • These antibodies target LDHC in Human, Mouse, Rat samples. (thermofisher.com)
  • Human monoclonal antibody. (abcam.com)
  • Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants. (invivogen.com)
  • IMC-002 is a fully human IgG4 monoclonal antibody designed to block the CD47-SIRPα interaction in order to promote the phagocytosis of cancer cells by macrophages. (prnewswire.com)
  • In later experiments they developed a proprietary monoclonal antibody against human CD79 (Curly 14) that has the capacity to desensitize the BCR in vitro. (nationaljewish.org)
  • The creation of a human CD79 expressing mouse model for in-vivo preclinical testing to optimize anti-CD79 therapy is underway. (nationaljewish.org)
  • We believe that this analysis of several mouse anti-CD40 antibodies can be used to develop strategies for producing new human anti-CD40 antibodies that can more effectively induce or block B-cell proliferation. (lu.se)
  • IgG fraction Monoclonal Mouse Anti-Digoxin may be used either as direct conjugates, or for more sensitivity, they can be used unconjugated followed by a conjugated anti-mouse IgG (H+L) for signal enhancement . (jacksonimmuno.com)
  • The next day, the membranes are washed at room temperature with agitation three times for 10 minutes in 5 % non-fat milk in TBST and incubated with a secondary antibody for two hours at room temperature with gentle rocking. (cdc.gov)
  • secondary antibodies. (antibodies-online.com)
  • IRDye 680LT Secondary Antibodies are supplied as purified immunoglobulin conjugates, lyophilized in phosphate-buffered saline, pH 7.4. (licor.com)
  • IRDye 680LT Secondary Antibodies are not intended for use in In-Cell Western ™ Assays or in vivo imaging applications. (licor.com)
  • Neither biologic nor clinical symptoms are specific but high antithyroid antibodies levels are characteristic. (nih.gov)
  • Literature shows that a close link exists between depression and antithyroid antibodies whatever thyroid status. (nih.gov)
  • Thyroid peroxidase (TPO, antimicrosomal antibody, antithyroid microsomal antibody) antibody - blood. (medlineplus.gov)
  • earchers can rely on our antibodies to deliver reproducible results over the lifecycle of their bioanalytical assays" she said. (the-scientist.com)
  • The discovery of immunoglobulin G anti-GQ1b antibodies in patients with Fisher syndrome and later in Bickerstaff brainstem encephalitis was crucial in providing the necessary evidence to conclude that both conditions were in fact part of the same spectrum of disease by virtue of their common clinical and immunological profiles. (nih.gov)
  • In SARS-CoV-2 infection, patients produce virus-specific B and T cells and then initially produce Immunoglobulin M (IgM) and later Immunoglobulin G (IgG) antibodies which are readily detected in serum [ 3 , 4 ]. (hindawi.com)
  • Anti-CD20 antibodies attach to the CD20 receptor and cause the tumor cells to disintegrate (lyse). (rxlist.com)
  • IMC-002 is an immune checkpoint inhibitor antibody, which blocks CD47-SIRP- α interaction between tumor cells and macrophages. (prnewswire.com)
  • however, it remains unknown whether the anti-tumor effects of anti-programmed cell death-1 antibody (PD-1-Ab) treatment are changed in hyperglycemic conditions. (nature.com)
  • Immune checkpoint inhibitors (ICIs), including antibodies against programmed cell death-1 (PD-1) and PD-1 ligand-1 (PD-L1), induce their anti-tumor effects by improving the function of immune cells 11 . (nature.com)
  • To investigate the effect of hyperglycemia on anti-tumor function induced by anti-PD-1 antibody treatment, we treated STZ-induced diabetic mice with subcutaneous MC38 colon carcinoma tumors with anti-PD-1 antibody, and examined changes in tumor growth, the number of tumor-infiltrating immune cells, and the expression of chemokines and chemokine receptors. (nature.com)
  • The effect of anti-PD-1 antibody on MC38 tumor is attenuated in STZ-induced diabetic mice. (nature.com)
  • In this clinical trial, the AAV vector designed by MGH investigators carries the genetic sequence for what is called a broadly neutralizing HIV-1 antibody that blocks HIV's ability to bind to CD4, an immune cell's receptor that HIV targets before infecting the cell. (sciencedaily.com)
  • The result is that numerous antibodies circulate to block any interaction between HIV and the CD4 receptor on immune cells, essentially shutting the door on HIV's entry into the cells. (sciencedaily.com)
  • In Nepal, immune response to SARS-CoV-2 in immune-compromised individuals, mainly in renal transplant recipients has not been reported till date and very less is known about neutralizing antibody response in them after vaccination. (hindawi.com)
  • In this study, we estimated circulating anti-SARS-CoV-2 antibody level after vaccination in three renal transplant patients who are concurrently receiving immune-suppressive drugs. (hindawi.com)
  • The company's mission is to bring safe, effective, and novel immunotherapies to oncology patients world-wide, and its portfolio includes diverse immune checkpoint antibodies. (prnewswire.com)
  • Based on these observations they produced antibodies against the BCR transducers, CD79a and b, and found that they "desensitize" the BCR and suppress the immune response, autoimmunity, and growth of non-Hodgkin's B lymphoma. (nationaljewish.org)
  • The CD40-CD40L interaction plays a critical role in both humoral and cellular immune responses and interfering antibodies have been suggested as an effective approach for the treatment of lymphomas and autoimmune diseases. (lu.se)
  • Antibodies One of the body's lines of defense ( immune system) involves white blood cells (leukocytes) that travel through the bloodstream and into tissues, searching for and attacking microorganisms and. (msdmanuals.com)
  • As a consequence, the identification of anti-GBM antibodies in the patient's serum or tissues is of paramount importance in the diagnosis of Goodpasture disease. (medscape.com)
  • Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader of life science research and clinical diagnostic products, today announced the launch of a range of anti-daratumumab antibodies that are specific for daratumumab (Darzalex) and inhibit the binding of the drug to its target, CD38. (the-scientist.com)
  • During the first incubation step, anti-HEV specific antibodies, if present, will be bound to the solid phase pre-coated HEV antigens. (cdc.gov)
  • However, with the exception of disease-agent-specific assays or functional assays, few reports describe the use of antibody detection assays in marine mammals. (usgs.gov)
  • Since anti-idiotype antibodies are specific for the variable region, they have become a useful tool in pharmacokinetic and immunogenicity studies. (rndsystems.com)
  • Take advantage of our antibody custom services to meet your specific needs. (rndsystems.com)
  • Some of our services include recombinant conversions, non-catalog antibody panels, and the ability to create anti-idiotype products to your specific target. (rndsystems.com)
  • To track VHH in patients, animal models, and cell cultures, specific anti-VHH antibodies are required. (genscript.com)
  • The Quantum Blue ® Anti-Infliximab rapid test allows for a highly specific detection of antibodies against the biologic within 15 min. (buhlmannlabs.ch)
  • However, for anti-HCV, the majority of laboratories report a positive result based on a positive screening test result only, and do not verify these results with more specific serologic or nucleic acid testing unless ordered by the requesting physician. (cdc.gov)
  • Unfortunately, certain health-care professionals lack an understanding of the interpretation of anti-HCV screening test results, when more specific testing should be performed, and which tests should be considered for this purpose. (cdc.gov)
  • [ 2 ] Anti-RA 33 antibody has been described as a highly specific antinuclear antibody for RA. (medscape.com)
  • Demonstration of a new antinuclear antibody (anti-RA33) that is highly specific for rheumatoid arthritis. (medscape.com)
  • Elevated levels of S100A8/A9 were particularly seen in patients with anti-dsDNA antibodies (p = 0.01) and glomerulonephritis before treatment (p = 0.02). (lu.se)
  • The anti-GBM antibodies can target the EA and EB epitope separately. (medscape.com)
  • [ 5 ] The more abundant D-hexamers have dimer-reinforced crosslinks between NC1 domains that help to retain the cryptic nature of the Goodpasture epitopes, whereas the less abundant M-hexamers, composed of only monomeric subunits, allow epitope unmasking and antibody binding under inflammatory states. (medscape.com)
  • The anti-idiotype antibody binds to the biosimilar antibody bound to its ligand on the cell (filled histogram). (rndsystems.com)
  • The blocking anti-idiotype antibody binds to the biosimilar antibody so it cannot bind to its ligand on the cell (orange histogram). (rndsystems.com)
  • Furthermore they established that anti-CD79a/b antibodies (intact, or mutants incompetent to bind IgG receptors and activate the complement cascade) block the development of disease and ameliorate ongoing target organ injury in MRL/LPR mouse model of Rheumatoid Arthritis, NOD mice for Type 1 Diabetes and EAE mouse model for MS. (nationaljewish.org)
  • Seroprevalence of anti-Lassa Virus IgG antibodies in three districts of Sierra Leone: A cross-sectional, population-based study. (bvsalud.org)
  • This cross-sectional study aimed to establish a baseline point seroprevalence of IgG antibodies to LASV in three administrative districts of Sierra Leone and identify potential risk factors for seropositivity and LASV exposure. (bvsalud.org)
  • Further, they tested P2G3 activity in antibody-dependent cellular phagocytosis (ADCP) and cytotoxicity (ADCC) assays. (news-medical.net)
  • We assessed S100A8/A9 and S100A12 levels in SLE patient sera in relation to disease activity, clinical phenotype, presence of anti-dsDNA antibodies and ability to promote phagocytosis of necrotic cells (NCs) by PMNs. (lu.se)
  • Pulmonary and/or renal manifestations can be encountered in various conditions, such as antineutrophilic cytoplasmic antibody (ANCA)-positive vasculitis and other autoimmune disorders. (medscape.com)
  • my docs actually are all in agreement that i have an autoimmune process (and thus an antibody) going on but that it just isn't one that's been pinned down yet. (dinet.org)
  • B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice. (nationaljewish.org)
  • We recently demonstrated that phage peptide libraries can be an excellent source of immunoreagents that facilitate the development of sandwich-type noncompetitive immunoassays for the detection of small analytes, avoiding the technical challenges of producing anti-immunocomplex antibody. (cdc.gov)
  • The antibodies are ideal for use as surrogate positive controls in anti-drug antibody assays, and for the development of pharmacokinetic bridging ELISAs to measure free drug. (the-scientist.com)
  • Anti-RA 33 antinuclear autoantibody in rheumatoid arthritis and mixed connective tissue disease: comparison with antikeratin and antiperinuclear antibodies. (medscape.com)
  • Western blot and Wantai IgG anti-HEV testing was performed to determine correlation with the DSI and Kuniholm NIH in-house IgG anti-HEV assays. (cdc.gov)
  • These anti-CD79 mAbs show therapeutic potential to induce reversible inhibition of BCR signaling and B cell function. (nationaljewish.org)
  • This antibody is found in ~80% of patients with coeliac disease. (wikipedia.org)
  • Anti-gliadin antibodies were one of the first serological markers for coeliac disease. (wikipedia.org)
  • In this article, Goodpasture disease and anti-GBM disease are used synonymously and refer to the presence of anti-GBM antibodies in tissues (eg, kidney, lungs, or both), independent of clinical manifestations. (medscape.com)
  • Differential susceptibility to anti-GBM disease in humans is strongly linked to class II major histocompatibility complex (MHC II). (medscape.com)
  • The use of the tested commercial antidog IgG antibody may be a valid approach to the detection of antibody response to disease in sea mammals. (usgs.gov)
  • The target of the most allergenic antibodies is ω-5 gliadin, which is encoded by the Gli-1B gene found on the B haplome (Aegilops speltoides derived) of wheat. (wikipedia.org)
  • however, since gluten is the target of the antibodies, that which would deplete them from the body, removal of gluten results in the benign circulation of antibodies. (wikipedia.org)
  • Bio-Rad offers a portfolio of recombinant, monoclonal, nonanimal-derived anti-idiotypic antibodies and drug-target complex binders for the development of highly selective and sensitive assays. (the-scientist.com)
  • When injected into a patient, the AAV therapy (called AAV8-VRC07) enters muscle cells, where the genetic sequence is read and translated to produce large quantities of the broadly neutralizing antibody (called VRC07) that are pumped out of the cells and travel through the blood to seek out their target. (sciencedaily.com)
  • The presence of anti-drug antibodies (ADA) against infliximab can diminish the effect of the biologic drug infliximab. (buhlmannlabs.ch)
  • The ease of use and a short incubation time offer fast and reliable qualitative measurement of free anti-drug antibodies against the biologic drug. (buhlmannlabs.ch)
  • In the absence of the biosimilar antibody, there is no binding of the anti-idiotype antibody to the cell (open histogram). (rndsystems.com)
  • It's also the first time we've had an approach capable of yielding broadly neutralizing antibodies against HIV in humans," he says. (sciencedaily.com)
  • No. A02014 ) is broadly reactive, and is ideal to be used for VHH antibody screening. (genscript.com)