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  • spores
  • There is an urgent need to devise more effective measures to protect U.S. citizens from the harmful effects of anthrax spores used as instruments of terror," said Secretary Thompson. (eurekalert.org)
  • It is hoped that a quicker administration time and other technological improvements would allow the vaccine to protect individuals from anthrax spores even if the vaccine was given shortly after exposure. (eurekalert.org)
  • Anthrax occurs in humans when they are exposed to infected animals, tissue from infected animals or when they are directly exposed to B. anthracis or its spores. (clinicaltrials.gov)
  • efficacy
  • The companies' challenge will be to take this experimental vaccine strategy through several stages of development, including manufacturing pilot lots of the vaccine, testing for safety in laboratory and clinical trials, testing for efficacy in animals, and preparing and submitting all necessary Food and Drug Administration (FDA) applications. (eurekalert.org)
  • bacterium
  • Anthrax is a zoonotic disease, occurring in wild and domestic mammals, caused by the spore-forming bacterium Bacillus anthracis (B. anthracis). (clinicaltrials.gov)
  • Furthermore
  • Furthermore, the vaccine could offer improved protection against inhaled B. anthracis, and could, when used in conjunction with antibiotics, form part of the management of anthrax exposed individuals. (clinicaltrials.gov)
  • infectious diseases
  • Vaccines are the best method of protecting the public against infectious diseases," said NIAID Director Anthony S. Fauci, M.D. "At NIAID, one of our top priorities is to work with industry to create new and improved vaccines against possible agents of bioterrorism. (eurekalert.org)