• While other scientists have previously developed global and continental landslide susceptibility maps, Kirschbaum and Stanley used improved versions of certain datasets. (nasa.gov)
  • Because of the uncertainties inherent in the susceptibility classification of extensive landscape areas as well as timing of landslide triggers, landslide susceptibility maps should be used with caution. (usgs.gov)
  • Accurate antibiotic susceptibility testing, or AST, is a key tool in addressing the rise in antibiotic-resistant bacteria. (asm.org)
  • The company believes Hyb & Seq may offer clear advantages over existing platforms in certain areas, including rapid detection of infectious pathogens and testing of their antibiotic susceptibility and resistance. (genomeweb.com)
  • Manually determine the antibiotic susceptibility of microorganisms using Antimicrobial Susceptibility Testing (AST) methods in conjunction with reliable, easy-to-use Thermo Scientific™ Oxoid™ Trimethoprim Antimicrobial Susceptibility discs. (thermofisher.com)
  • Understand the challenges you will confront when interpreting antibiotic susceptibility test results based on minimum inhibitory concentration (MIC) accuracy. (beckmancoulter.com)
  • NEW YORK (Reuters Health) - Proper use of rapid susceptibility testing could limit the spread of antibiotic resistance in gonorrhea, according to a modeling study. (medscape.com)
  • I expected that availability of a point-of-care (POC) test that could inform on susceptibility and allow us to use another antibiotic would be helpful," Dr. Grad said. (medscape.com)
  • Exciting technological advances and growth in understanding of the biology and genetics of resistance herald a time in the near future when new rapid point-of-care diagnostics can diagnose infections and report antibiotic susceptibility," Dr. Grad concluded. (medscape.com)
  • Candidate gene studies represent the most common form of genetic association study performed to find asthma-susceptibility genes. (medscape.com)
  • Susceptibility to the development of Crohn's disease involves a combination of genetic and environmental factors. (medscape.com)
  • While this genetic alteration needs to be explored further to fully understand the role it plays, it offers insights into the molecular mechanisms underlying susceptibility to COVID-19 and other immune-related diseases, providing a basis for developing potential therapies harnessing these genetic mechanisms. (sanger.ac.uk)
  • In addition, a number of different genetic determinants of IS risk have been identified in genome-wide association studies, with single-nucleotide polymorphisms (SNPs) in 9p21, PITX2, HDAC9, ABO, NINJ2, ALDH2, and TSPAN2, all being linked with stroke susceptibility [ 2 ]. (hindawi.com)
  • These SNPs, however, are still thought to account for less than half of all genetic susceptibility to IS, with a number of yet to be discovered genes also contributing to the development of IS. (hindawi.com)
  • In order to evaluate the impact of genotype-by-Vit D interactions on EAE susceptibility, the researchers used a chromosome substitution mouse model (consomic) that involved the genetic diversity of wild-derived PWD/PhJ (PWD) mice. (ajmc.com)
  • It is well recognised that only a proportion of cigarette smokers develop COPD, 8, 9 and that this is likely to be the result of genetic susceptibility to the effects of cigarette smoke. (bmj.com)
  • A postdoctoral opportunity is immediately available at the Genetic Cancer Susceptibility Group. (who.int)
  • Ecogenetics : genetic variation in susceptibility to environmental agents / Edward J. Calabrese. (who.int)
  • National Healthcare Safety Network (NHSN) is a surveillance system for healthcare-associated infections (HAIs) that includes data collection on antimicrobial susceptibility testing results for certain reported pathogens. (cdc.gov)
  • Six isolates of S. aureus obtained from one specimen from this patient in July were sent to CDC for species confirmation and antimicrobial susceptibility testing. (cdc.gov)
  • However, treatment has been compromised by the absence of routine antimicrobial susceptibility testing in clinical care and evolution of antimicrobial resistance to the antibiotics used to treat gonorrhea. (cdc.gov)
  • If treatment failure is suspected, clinicians should submit a stool specimen for antimicrobial susceptibility testing, and consider consulting an infectious disease specialist to identify best treatment options. (cdc.gov)
  • Collect a stool specimen for culture, and work with your clinical microbiology laboratory to submit for additional antimicrobial susceptibility testing. (cdc.gov)
  • Although they only minimally advance the field, studies such as these are the most commonly performed scientific investigation of asthma-susceptibility genes. (medscape.com)
  • [ 4 ] These genes are thought to be involved in atopy, bronchial hyperresponsiveness, elevated IgE levels, and other asthma-related traits, although the effect of each gene on asthma susceptibility seems to be small. (medscape.com)
  • [ 6 , 13 ] All of the genes identified seemed to support a role for disordered inflammatory/immunologic responses, but the precise mechanism and impact of each gene on asthma susceptibility has yet to be elucidated. (medscape.com)
  • The study, published in Nature Genetics (12 June), helps to unpick the relationship between specific genes, their expression levels, and their potential connection in disease susceptibility. (sanger.ac.uk)
  • We used recombinant congenic mouse strains to map asthma susceptibility genes on mouse chromosome 17. (rug.nl)
  • Comparing the DNA from patients at the best and worst extremes of a health condition can reveal genes for resistance and susceptibility. (washington.edu)
  • We identified 3 strong asthma susceptibility loci, lmr1A, lmr1B and H2. (rug.nl)
  • He added that the ability to support rapid infectious disease detection and drug susceptibility testing could be one of the "killer applications" for Hyb &Seq, a sequencing-by-hybridization platform in which DNA or RNA is read six bases at a time through the use of thousands of unique hexamer barcodes. (genomeweb.com)
  • The MIC allows correlation between drug susceptibility of the organism and the achievable tissue concentration of free drug (ie, drug not bound to protein). (msdmanuals.com)
  • CMAP has developed urban and riverine flood susceptibility indexes (FSI) to identify priority areas across the region for flood mitigation activities. (illinois.gov)
  • instead, they are designed to identify larger scale priorities across the region for mitigation activities and help inform flood susceptibility in communities lacking more technical analysis. (illinois.gov)
  • See the Guide to Flood Susceptibility and Stormwater Planning for information on how to use the FSI in planning activities. (illinois.gov)
  • CMES Deputy Director Ronny Berndtsson has co-authored an article on flood susceptibility prediction in Afghanistan, published in the journal Natural Hazards. (lu.se)
  • CMES Deputy Director Ronny Berndtsson has co-authored the article "Flood susceptibility prediction using MaxEnt and frequency ratio modeling for Kokcha River in Afghanistan" together with Abdul Baser Qasimi (Samangan University) and Vahid Isazade (Kharazmi University). (lu.se)
  • In total, 88 flood points collected from Google Earth were used to train the frequency ratio model to predict flood susceptibility, and 34 GPS-recorded points of the flooded area were used to evaluate the model's performance. (lu.se)
  • The developed models can help planners and decision-makers perform flood susceptibility mapping in the region by determining locations of flooding sensitivity. (lu.se)
  • First, we investigated the power of this approach for the mapping of asthma susceptibility using the CcS/Dem series. (rug.nl)
  • We then started to map asthma susceptibility in the Lmr series of recombinant congenic and subcongenic strains. (rug.nl)
  • Identification of N. gonorrhoeae infections with reduced ceftriaxone susceptibility can be a sign of emerging resistance. (cdc.gov)
  • No Azi-RS isolates exhibited reduced cefixime or ceftriaxone susceptibility (Cfx-RS and Cro-RS, respectively). (cdc.gov)
  • Using a 30-meter digital elevation model to classify hillslope angle, a digital map of bedrock geology, and maps showing the locations of landslides associated with a severe storm in October 1985, the municipality was classified into areas of low, moderate, and high susceptibility to landslides triggered by heavy rainfall. (usgs.gov)
  • The results of the cystic fibrosis infection susceptibility study appear July 8 in Nature Genetics. (washington.edu)
  • Exome Sequencing Project scientists are using an approach similar to the one in this study to examine the genetics behind resistance and susceptibility to other chronic conditions like obesity, heart attacks and hypertension. (washington.edu)
  • To accurately detect staphylococci with reduced susceptibility to vancomycin, antimicrobial susceptibility should be determined with a quantitative method (broth dilution, agar dilution, or agar gradient diffusion) using a full 24 hours of incubation at 95 F (35 C). Strains of staphylococci with vancomycin MICs of 8 ug/mL were not detected using disk-diffusion procedures. (cdc.gov)
  • Detailed recommendations for the prevention, detection, and control of S. aureus strains with reduced susceptibility to vancomycin are outlined in 'Interim Guidelines for Prevention and Control of Staphylococcal Infection Associated with Reduced Susceptibility to Vancomycin,' published previously in MMWR (4). (cdc.gov)
  • The Gonococcal Isolate Surveillance Project (GISP) was established in 1986 as a sentinel surveillance system to monitor trends in antimicrobial susceptibilities of N. gonorrhoeae strains in the United States. (cdc.gov)
  • Despite the MIC decrease (i.e., trend of improved cefixime susceptibility) during 2012-2013, the increase in the number of strains with Cfx-RS in 2014 underscores the potential threat of cephalosporin-resistant N. gonorrhoeae . (cdc.gov)
  • Antimicrobial susceptibility data revealed increasing resistance to co-trimoxazole and ampicillin, but strains remained highly susceptible to ofloxacin. (who.int)
  • This is a follow-up to HAN 401: CDC Recommendations for Diagnosing and Managing Shigella Strains with Possible Reduced Susceptibility to Ciprofloxacin . (cdc.gov)
  • [ Jurisdictions can consider including ] Laboratories are encouraged to maintain all Neisseria gonorrhoeae isolates demonstrating reduced cephalosporin susceptibility until further notice. (cdc.gov)
  • A comparison between elevation and landslide susceptibility (the third image) shows that many of the lower-elevation areas in the Himalaya foothills are more susceptible than steeper, high-elevation areas on the Tibetan Plateau. (nasa.gov)
  • Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. (sanger.ac.uk)
  • Using GASPACHO (GAuSsian Processes for Association mapping leveraging Cell HeterOgeneity), researchers at the Wellcome Sanger Institute, the National Center for Child Health and Development in Japan, Tel Aviv University and their collaborators have identified a gene variant that affects COVID-19 susceptibility. (sanger.ac.uk)
  • When the researchers added the adolescents' baseline susceptibility status to the model, it became the strongest predictor of experimentation, causing a 2.6-fold increase in risk, and all other influences accept age and living with a smoker were no longer statistically significant. (scienceblog.com)
  • The researchers identified 805 different DNA methylation regions that can potentially act as an epigenetic biomarker for susceptibility to father offspring with autism. (news-medical.net)
  • All three headlines are among 20 compiled by researchers into a new Misinformation Susceptibility Test - the MIST - designed to measure how well you can discern real and fake news, and distinguish them from each other, in two minutes. (niemanlab.org)
  • Researchers from the Mayo Clinic have identified a possible method of predicting patients' susceptibility to COVID-19 using DNA sequencing. (medpagetoday.com)
  • Resistance folder within the Unusual Susceptibility Profile Alerts sub-folder. (cdc.gov)
  • This is the first report to present comprehensive surveillance data from GISP and summarize gonococcal susceptibility over time, as well as underscore the history and public health implications of emerging cephalosporin resistance. (cdc.gov)
  • Ceftriaxone and azithromycin are first-line drugs used for empiric treatment of gonorrhea while awaiting culture and susceptibility results, but there is increasing resistance to both antibiotics. (medscape.com)
  • Dr. Teodora Elvira Wi from the World Health Organization in Geneva, who recently reviewed the challenges of antimicrobial resistance in gonococci, told Reuters Health by email, "Modeling of the use of point-of-care test to determine gonococcal treatment susceptibility and tailor fit patient treatment based on susceptibility information can delay the overall resistance for several years. (medscape.com)
  • Isolates are tested for antimicrobial susceptibility using agar dilution at one of five regional laboratories. (cdc.gov)
  • Reduced azithromycin susceptibility (Azi-RS) (defined as minimum inhibitory concentration [MIC] ≥2.0 µ g/mL) increased from 0.6% in 2013 to 2.5% in 2014. (cdc.gov)
  • Among those tested, 16.5% have a ciprofloxacin MIC in the 0.12-1 μg/mL range, and 22.1% have reduced susceptibility to azithromycin. (cdc.gov)
  • Thus the volume magnetic susceptibility χv and the magnetic permeability μ are related by the following formula: μ = μ 0 ( 1 + χ v ) . {\displaystyle \mu =\mu _{0}\left(1+\chi _{\text{v}}\right). (wikipedia.org)
  • My goal is to carry out genomic fine-mapping of the region of the human genome around TNF, to determine the causal basis of associations between TNF polymorphisms and susceptibility to severe malaria in African children. (europa.eu)
  • These findings suggest an effect for RAD50 and NBS1 haploinsufficiency on genomic integrity and susceptibility to cancer. (lu.se)
  • 2021) Sperm DNA methylation epimutation biomarker for paternal offspring autism susceptibility. (news-medical.net)
  • Facial wrinkling in smokers may therefore be a biomarker of susceptibility to COPD. (bmj.com)
  • The template health alert below can be adapted and used by a health department to notify local public health practitioners, clinicians, public health laboratories, and public information officers about a case, cluster or isolate of reduced susceptibility N. gonorrhoeae in their jurisdiction. (cdc.gov)
  • 2000. Sadness and Susceptibility to judgmental bias: The case of anchoring. (northwestern.edu)
  • To address this key question, we used in vivo time-course analysis of OA development and murine interstrain variability in natural susceptibility to OA to examine changes in non-OA-prone CBA mice versus OA-prone STR/Ort mice, which develop disease that bears significant histologic resemblance to human OA. (bepress.com)
  • Ignoring uncertainty introduced through multiple factors-interlaboratory variability, biological differences, incubation temperature fluctuations, time ranges, proximity to breakpoints and others-influences the results of antimicrobial susceptibility test results. (beckmancoulter.com)
  • A recent study found that the association between vitamin D (Vit D) status and multiple sclerosis (MS) susceptibility is genotype dependent and suggested that the outcome of Vit D status in MS is determined by gene-by-sex interactions. (ajmc.com)
  • Taken together, our results support the observation that the association between VitD status and MS susceptibility is genotype dependent and suggest that the outcome of VitD status in MS is determined by gene-by-sex interactions. (ajmc.com)
  • Krementsov D, Asarian L, Fang Q, McGill M, Teuscher C. Sex-specific gene-by-vitamin D interactions regulate susceptibility to central nervous system autoimmunity [published online July 17, 2018]. (ajmc.com)
  • Antimicrobial susceptibility tests can guide the physician in drug choice and dosage for difficult-to-treat infections. (medscape.com)
  • We cast these considerations into the new model of R- Susceptibility, which can inform and alert users about their potential for being targeted, and devise measures for quantitative risk assessment. (mpg.de)
  • Our results suggest that prevention efforts tailored to an adolescent's susceptibility status may be more effective among Mexican-American youth," said senior author Anna Wilkinson, Ph.D., assistant professor in M. D. Anderson's Department of Epidemiology. (scienceblog.com)
  • Thus, susceptibility test results do not always predict treatment outcome. (msdmanuals.com)
  • Personal view: food for thought--western lifestyle and susceptibility to Crohn's disease. (medscape.com)
  • A new hypothesis is proposed, by which excessive delivery of highly fermentable but poorly absorbed short-chain carbohydrates and polyols (designated FODMAPs--Fermentable Oligo-, Di- and Mono-saccharides And Polyols) to the distal small intestinal and colonic lumen is a dietary factor underlying susceptibility to Crohn's disease. (medscape.com)
  • Now we've uncovered significant evidence that a high abundance of Ca. Aquarickettsia is a marker of disease susceptibility in corals that otherwise seem healthy. (sciencedaily.com)
  • Disentangling the role of pulmonary impairment in lung cancer development is important from an etiological perspective, for refining disease susceptibility mechanisms, and for informing precision prevention and risk stratification strategies. (nature.com)
  • Facial wrinkling is associated with COPD in smokers, and both disease processes may share a common susceptibility. (bmj.com)
  • Active surveillance of serotypes and antimicrobial susceptibility is essential to predict future epidemics and define measures to curtail the disease. (who.int)
  • While previous studies had demonstrated the importance of susceptibility among other ethnic groups, this study was the first to examine its role leading to experimentation among Mexican-American youth. (scienceblog.com)
  • Through the study of early antimalarial transcriptional and functional cellular responses in two ethnic groups with differing susceptibility to malaria, we will identify the key innate pathways which underlie this differential ability to control parasitemia. (yale.edu)
  • VITEK 2 Gram Negative Susceptibility Card, AST-N107, REF 22 265, For In Vitro Diagnostic Use, 20 cards/box. (fda.gov)
  • Cards that are intended for use with the Vitek 2 Systems in clinical laboratories as an in vitro test to determine the susceptibility of clinically significant aerobic/anaerobic gram-negative bacilli to antimicrobial agents. (fda.gov)
  • Susceptibility testing occurs in vitro and may not account for many in vivo factors (eg, pharmacodynamics and pharmacokinetics, site-specific drug concentrations, host immune status, site-specific host defenses) that influence treatment success. (msdmanuals.com)
  • Susceptibility to smoking is a measurable characteristic that predicts transition to smoking. (scienceblog.com)
  • Imagine a simple blood test that predicts patients' susceptibility to SARS-CoV-2. (medpagetoday.com)
  • Currently, clinical laboratories have limited ability to differentiate the ciprofloxacin MIC values within the reduced susceptibility range, ≤1 μg/mL. (cdc.gov)
  • Functional studies revealed that some variants increased protein expression, which might increase viral susceptibility and severity, while other variants decreased protein expression, possibly exerting a protective effect. (medpagetoday.com)
  • The current research is aimed at assessing the correlation between two functional GAS5 variants (rs145204276 and rs55829688) and susceptibility to IS in a Han Chinese population. (hindawi.com)
  • The result of this classification indicates that 34 percent of the municipality has high susceptibility to rainfall-triggered landsliding, 24 percent has moderate susceptibility, and 9 percent has low susceptibility. (usgs.gov)
  • Quantitative measures of the magnetic susceptibility also provide insights into the structure of materials, providing insight into bonding and energy levels. (wikipedia.org)
  • When a user enters a pathogen's susceptibility testing result into the NHSN application that aligns with one of the unusual susceptibility profiles, upon saving the event, a "pop-up" message will appear on the screen. (cdc.gov)
  • Susceptibility testing can be done for bacteria, fungi, and viruses. (msdmanuals.com)
  • Susceptibility testing can be done qualitatively, semiquantitatively, or using nucleic acid-based methods. (msdmanuals.com)
  • Perinatal exposure to foodborne inorganic nanoparticles: A role in the susceptibility to food allergy? (frontiersin.org)
  • The current review focuses on the possible impacts of perinatal exposure to foodborne NP during pregnancy and early life on the susceptibility to developing FA. (frontiersin.org)
  • This study aimed to evaluate the frequency and antimicrobial susceptibility profile of non-O1 and non-O139 V. cholerae in Pakistan. (who.int)
  • This association was most notable in patients with non-pulmonary sepsis (an indirect, vasculature-targeted mechanism of lung injury) and persisted in patients who lacked epithelial expression of the A antigen, suggesting an endothelial mechanism of A1-associated ARDS susceptibility. (jci.org)
  • It is hoped the tool can be applied to discover further susceptibility mechanisms across other human disorders. (sanger.ac.uk)
  • We also hoped to find interactions between hypnotic susceptibility and dissociation with paranormal experiences. (bvsalud.org)
  • Mexican-American adolescents are more inclined to experiment than other groups, and experimentation is likely to lead to a permanent habit, so understanding susceptibility offers an opportunity for early intervention, the authors note. (scienceblog.com)
  • Future studies need to focus on understanding and targeting risk factors for susceptibility to prevent experimentation and habitual smoking, the authors note. (scienceblog.com)
  • Understanding what, exactly, underpins susceptibility to misinformation is critical to effectively fight it. (niemanlab.org)
  • Impaired lung function is often caused by cigarette smoking, making it challenging to disentangle its role in lung cancer susceptibility. (nature.com)
  • Here we report the association of three Mre11 complex mutations with hereditary breast cancer susceptibility, studied by using a case-control design with 317 consecutive, newly diagnosed Northern Finnish breast cancer patients and 1000 geographically matched healthy controls (P = 0.0004). (lu.se)
  • The map is part of a broader effort to establish a hazards monitoring system that combines satellite observations of rainfall from the Global Precipitation Measurement (GPM) mission with an assessment of the underlying susceptibility of terrain. (nasa.gov)
  • We have tested the hypothesis that there is a common susceptibility for the development of COPD and facial wrinkling in cigarette smokers. (bmj.com)
  • The objective of our study was to test the hypothesis that there is a common susceptibility for the development of airflow obstruction and facial wrinkling in cigarette smokers. (bmj.com)
  • Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis. (bepress.com)