Cloning and characterization of a novel functional organic anion transporting polypeptide 3A1 isoform highly expressed in the human brain and testis. (bioinformatics.hu)
Superoxide anion1
Phagocytic cells yield high concentrations of microbicidal ROS (reactive oxygen varieties) like hydrogen peroxide and superoxide anion during phagocytosis to assault invading foreign pathogens. (enmd-2076.com)
Transporter1
auxotrophy inside a mutant from the ABC sulfate transporter complicated. (exposed-skin-care.net)
Polypeptide1
Desk 1 The SLC26 Multifunctional Anion Exchanger /Anion Route gene Family includes a one SulP polypeptide, YchM. (exposed-skin-care.net)
Annotations1
Gray triangles = other expression annotations only (e.g. absence of expression or data from mutants). (jax.org)
Normotensive2
In this report, we describe the construction and hemodynamic characterization of a congenic strain of SHR (SHR-Lx) that carries a defined segment of chromosome 8 from a normotensive strain of Brown-Norway rats (BN-Lx strain). (jci.org)
A strain of Rattus norvegicus used as a normotensive control for the spontaneous hypertensive rats (SHR). (lookformedical.com)
Chromosome3
Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat. (jci.org)
Transfer of this segment of chromosome 8 from the BN-Lx strain onto the SHR background resulted in substantial reductions in systolic and diastolic blood pressure and cardiac mass. (jci.org)
These findings demonstrate that BP regulatory gene(s) exist within the differential chromosome segment trapped in the SHR-Lx congenic strain and that this region of chromosome 8 plays a major role in the hypertension of SHR vs. BN-Lx rats. (jci.org)
Gene3
The phylogenetically ancient SLC26 gene family encodes multifunctional anion exchangers and anion channels transporting a wide selection of substrates, including Cl? (exposed-skin-care.net)
To investigate the potential role of Lsm1p in response to UV radiation, we constructed double mutant strains in which LSM1 was deleted in combination with a representative gene from each of three known yeast DNA repair pathways. (bioone.org)
Yeasts are unicellular eukaryotic fungi and they belong to the phyla Ascomycota (e.g., etc.,) and Basidiomycota (e.g., strains is the capability of transfer of resistant gene to the pathogenic bacteria. (enmd-2076.com)
Mutagenicity2
In the NTP study (NTP, 2013) cobalt metal was evaluated for bacterial mutagenicity in 2 strains of Salmonella typhimurium (TA98 and TA100) and 1 strain of E. coli (WP2 uvrA/pKM101) using the pre-incubation method. (europa.eu)
Relevant of mutagenicity and clastogenici- angiosarcomas of the liver, which carcinogens discussed in this chap- ty, including the induction of sister are rare tumours, were identified in ter do not include pharmaceutical chromatid exchange (SCE), chro- humans, rats, and mice exposed to drugs classified in Group 1, which mosomal aberrations (CA), and mi- vinyl chloride. (who.int)
Mice2
or each of these agents, carcinogenicity in rats and/or mice, els, differences in exposure con- there was sufficient evidence of car- for example for the liver (aflatoxins, ditions between studies in animals cinogenicity from studies in rats and/ trichloroethylene [TCE], and vinyl and in humans, or limitations in Part 1 · Chapter 1. (who.int)
Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice. (jci.org)
Utilizing2
Utilizing two further mutants of low-adhesive FimH proteins via Ersus. (phosphorylasesignals.com)
Utilizing the in-vitro studies as well as rats models, this manuscript illustrates the different regulatory mechanisms of exercise and antioxidant intervention on redox balance/redox state(s) that are linked to improved glucose control and thereby effective management of diabetes. (elifesciences.org)
Hypertension2
The spontaneously hypertensive rat (SHR) is the most widely studied animal model of essential hypertension. (jci.org)
A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke. (lookformedical.com)
Mutations1
Evidence that cobalt sulfate heptahydrate was a weak inducer of mutations in Salmonella typhimurium strain TA100 when using the pre-incubation method was published by Zeiger et al (1992), when reporting on NTP studies. (europa.eu)
Enzyme3
The enzyme activities of recombinant strains over-expressing PDI and CPR5 reached the highest levels of 259.47 U/mL and 161.34 U/mL, 635% and 357% higher than the original enzyme activity, respectively. (inra.fr)
Transcriptomic analysis of the two recombinant strains in comparison with the control strain showed that the correct folding of proteins assisted by molecular chaperones played a key role in the improvement of FumDM expression and its enzyme activity. (inra.fr)
It is stated that the studied coordination compounds render both activating and inhibiting effect on enzyme activity, depending on composition, structure, charge of complex, coordination number of complex former and also on the enzyme and strain producer. (ukrbiochemjournal.org)
Hippocampal1
Interestingly, ginsenosides extracted from Panax ginseng reduced the hippocampal and cortical expression of phosphorylated tau in a rat model of AD. (megazyme.com)
Commonly1
Rats, Inbred WF are a strain of laboratory rats that are commonly used in medical research due to their consistent genetic makeup and susceptibility to various diseases. (lookformedical.com)
Capability1
Here, by comparing exercise and antioxidant intervention on type 2 diabetic rats, we found moderate exercise upregulated compensatory antioxidant capability and reached a higher level of redox balance in the liver. (elifesciences.org)
Metabolic3
By performing the same task, light-driven anion pumps can considerably reduce the use of metabolic energy. (wikipedia.org)
Approximately 2-fold increases in TA100 revertants were seen in 3 separate experiments in the absence of metabolic activation (rat or hamster liver S9), with a peak response at 333 µg/plate in each experiment. (europa.eu)
A 2011 study in rats investigated the use of a combination of the Chinese herbs jiaogulan, coptis , and red sage in the treatment of metabolic syndrome, a combination of symptoms and cardiac risk factors that result from obesity-related insulin resistance . (thischickisraw.com)
Tissue1
Ramsamooj R, Llull R, Black KS, Hewitt CW (1999) Composite tissue allografts in rats: IV. (tradingsignalsforex.com)
Matrix1
Cellular studies of NTD and CTD oligomerization interface mutants demonstrate the importance of each interface in matrix assembly. (uci.edu)
Type3
The δ subunit mRNA was present at wild-type levels in the mutant granule cells, indicating a post-translational loss of the δ subunit. (jneurosci.org)
The β1-subunit homologous mutant β2(V436T) substantially diminished the efficacy of both drugs to a third of that obtained with wild-type β2 subunit combinations, but without changing potency. (researchgate.net)
Comparison of the volatile profile produced by an engineered mutant impaired in quorum-sensing (QS) signalling with the corresponding wild-type led to the conclusion that QS is not involved in the regulation of volatile production in B. Fosbretabulin research buy ambifaria LMG strain 19182. (bcl2signaling.com)
Control1
The control revertant numbers for 2 of the strains (TA1535 and TA1537) are unusually high, and therefore the reliability of the study is questionable. (europa.eu)
Studies1
Based on these preliminary studies, researchers from the University of Sydney set out to investigate the effects of jiaogulan gypenosides in rats with induced hyperlipidemia. (thischickisraw.com)
Human1
The STAS domain name shown may be the backbone framework of the human being pendrin STAS domain name encompassing aa 515C734 (excluding the intervening series (IVS) area of aa 566C653 between helix 1 and strand 3), as modeled with PyMOL through the X-ray crystal framework of rat SLC26A5/prestin (PDB Identification 3LLO). (exposed-skin-care.net)
Study1
In this study, a uricase-producing strain (named CSAJ-16) was isolated from the soil sample of Cangshan Mountain, Yunnan Province, China. (bvsalud.org)
Widely1
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. (lookformedical.com)
Effect1
The salt effect cannot be described in terms of Debye screening, but involves the ion-specific sequestering of anions within the narrow channel. (lu.se)
Animals1
Rats bearing mutant genes which are phenotypically expressed in the animals. (lookformedical.com)
Blood1
Superoxide dismutase (SOD) activity of rat blood was determined using SOD activity assay kit (E-BC-K022-M). (elabscience.com)
Disease1
Mutant strain of Rattus norvegicus which is used as a disease model of kernicterus. (lookformedical.com)