SulfateHuman organic anion transporterSerum phosphateCationRenalPhosphoric acidPyrophosphateCations and anionsAqueousHydrogenAcetateSodium phosphateInorganic phosphatePO43CalciumIonsDivalentMonovalentEsterOrganic anionsSuperoxideCompoundsAbstractExcretionAnionicLactateHOAT1LigandsRetentionAcidFunctional groupAcidosisSeparationOccurMetabolismRolesUptakeUrinarySolubleBufferProcessesMmolOxygenEnzymeDeterminationInteractionsPhosphorusChainsBloodPlasmaForm
Sulfate7
- and hydrogen sulfate (HSO 4 − ) anions. (rsc.org)
- Fifty percent of plasma calcium is ionized, 40% is bound to proteins (90% of which binds to albumin), and 10% circulates bound to anions (eg, phosphate, carbonate, citrate, lactate, sulfate). (medscape.com)
- A sulfate anion in the ATP binding pocket mimics the beta-phosphate group of an adenine nucleotide. (rcsb.org)
- At site 1, three side chains and a sulfate or phosphate anion are involved in metal coordination. (rcsb.org)
- The developed process achieves around 70% phosphorus recovery as an industrial-grade (19 wt% P) dicalcium phosphate dihydrate product with minimal iron, magnesium, and aluminum contamination, while also producing value-added calcium sulfate dihydrate (gypsum) and iron/magnesium byproducts. (rsc.org)
- Inorganic anions sulfate (-2 charge), phosphate (-3 charge) and pyrophosphate (-4 charge) are noted. (thermofisher.com)
- To date, we have found components from the aging of lithium-ion battery anodes in several classes, including carboxylic acids, esters, phosphate esters, sulfate esters, as well as inorganic anions. (thermofisher.com)
Human organic anion transporter1
- A cDNA clone was isolated from a human renal library and designated human organic anion transporter 1 (hOAT1). (aspetjournals.org)
Serum phosphate3
- Elevated levels of serum phosphate may be associated with a higher risk of death and adverse cardiovascular outcomes in people with prior myocardial infarction, and is the subject of large amount of research. (immunochemistry.com)
- Secondary endpoints are measurement of serum phosphate levels, other acid-base parameters such as the strong ion difference (SID), the onset and severity of postoperative nausea and vomiting (PONV), electrolyte levels and their excretion in the urine, monitoring of renal function and glycocalyx components, haemodynamics, amounts of catecholamines and other vasopressors used and the safety of the infusion regime. (biomedcentral.com)
- The normal serum phosphate concentration in adults ranges from 2.5 to 4.5 mg/dL (0.81 to 1.45 mmol/L). Phosphate concentration is 50% higher in infants and 30% higher in children, possibly because of the important roles the phosphate-dependent processes play in growth. (msdmanuals.com)
Cation2
Renal4
- The secretion of numerous organic anions, including endogenous metabolites, drugs, and xenobiotics, is an important physiological function of the renal proximal tubule. (aspetjournals.org)
- Importantly, both hOAT1 and rat renal organic anion transporter 1 (rROAT1) mediated saturable, probenecid-sensitive uptake of cidofovir, adefovir, and other nucleoside phosphonate antivirals. (aspetjournals.org)
- Renal phosphate excretion roughly equals gastrointestinal absorption to maintain phosphate balance. (msdmanuals.com)
- Primary metabolic acidoses that occur as a result of a marked increase in endogenous acid production (eg, lactic or keto acids) or progressive accumulation of endogenous acids when excretion is impaired by renal insufficiency are characterized by decreased plasma bicarbonate concentration and increased anion gap without hyperchloremia. (medscape.com)
Phosphoric acid3
- 2 The phosphate rock is converted to phosphoric acid (H 3 PO 4 ) which is used to produce phosphate fertilizers. (rsc.org)
- In the wet phosphoric acid process, the phosphate rock is reacted with sulfuric acid (H 2 SO 4 ), producing gypsum (CaSO 4 ·2H 2 O) and aqueous phosphoric acid (reaction (1) ). (rsc.org)
- In chemistry, a phosphate is an anion, salt, functional group or ester derived from a phosphoric acid. (top500.de)
Pyrophosphate2
- The host-guest interaction between orthophosphate, pyrophosphate and triphosphate anions and three cyclen based macrotricyclic ligands possessing ortho- (TOC), meta- (TMC) and para-xylenyl (TPC) linkers was investigated by potentiometric measurements. (univ-brest.fr)
- The pyrophosphate anion is unstable in aqueous solutions with the degree of instability varying according to pH. (europa.eu)
Cations and anions3
- excellent long- and short-term precision in relative retention times were obtained for both cations and anions. (unboundmedicine.com)
- A1 - Lurie,I S, PY - 1996/9/1/pubmed PY - 1997/12/31/medline PY - 1996/9/1/entrez SP - 237 EP - 42 JF - Journal of capillary electrophoresis JO - J Capillary Electrophor VL - 3 IS - 5 N2 - Methodology is presented for the analysis of cations and anions in illicit heroin using CE with indirect UV detection. (unboundmedicine.com)
- The AG value represents the difference between unmeasured cations and anions, ie, the presence of anions in the plasma that are not routinely measured. (medscape.com)
Aqueous2
- Inclusion of long aliphatic chains on these ligands allows the assemblies to extract anions from aqueous media into organic solvents . (bvsalud.org)
- We are developing luminescent europium(III) complexes 2-6 capable of reversibly binding and discriminating between nucleoside tri-, di- and monophosphate anions in aqueous biological media (Figure 1). (edu.au)
Hydrogen3
- Anion adsorption peak positions are determined for solution phase anion concentrations present in microbial fuel cells and microbial electrolysis cells and discussion is provided as to the impact of anion adsorption on oxygen reduction and hydrogen evolution reaction rates in these devices. (psu.edu)
- The substrate is converted to Hydrogen peroxide in presence of inorganic phosphate in a coupled enzymatic reaction. (immunochemistry.com)
- as bicarbonate anions and phosphate anions prevent hydrogen cations from doing so. (medfriendly.com)
Acetate3
- Density functional theory (DFT) methods are used to predict the adsorption free energy of acetate and phosphate anions as a function of Pt(1 1 1) electrode potential. (psu.edu)
- The Langmuir model is sufficient for predicting the adsorption peak shape, indicating coverage effects are minor in altering the LSV for acetate and phosphate adsorption. (psu.edu)
- Savizi, ISP & Janik, MJ 2011, ' Acetate and phosphate anion adsorption linear sweep voltammograms simulated using density functional theory ', Electrochimica Acta , vol. 56, no. 11, pp. 3996-4006. (psu.edu)
Sodium phosphate2
- Sodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy. (sigmaaldrich.com)
- Each 15 mL contains 7.2 g monobasic sodium phosphate monohydrate and 2.7 g dibasic sodium phosphate heptahydrate. (medscape.com)
Inorganic phosphate2
- The assay is based on an enzyme-coupled reaction that detects inorganic phosphate. (immunochemistry.com)
- In distilled water pyrophosphates will hydrolyse slowly via abiotic mechanisms to inorganic phosphate. (europa.eu)
PO431
Calcium3
- The amount in stool varies depending on the amount of phosphate-binding compounds (mainly calcium) in the diet. (msdmanuals.com)
- Phosphate, which works together with calcium to build strong bones and teeth. (medlineplus.gov)
- Some physicochemical characteristics influence the erosivity of food like the type of acid, pH, titratable acidity, chelating potential, calcium and phosphate concentration, temperature and adhesion 4 . (bvsalud.org)
Ions3
- In these phosphate and phosphite form bridging ligands to hard metal ions. (wikipedia.org)
- ions) are phosphate and bicarbonate. (medfriendly.com)
- Anions elute in this separation in order of valency on the anion exchange column but are detected as singly-charged ions in the mass spectrometer. (thermofisher.com)
Divalent2
- For example, the anion with a m/z of 125.0009 must be monovalent at the found retention time, so the probable species is the monovalent phosphate ester, dimethylphosphate, as opposed to a divalent species ethylhydrogenphosphate. (thermofisher.com)
- Phosphate is a divalent anion largely absorbed in the proximal small intestine. (medscape.com)
Monovalent1
- In water solutions, this substance is present as a monovalent anion, ascorbate- (Asc-), which easily donates electrons to oxidized molecules and scavenges reactive oxygen species (ROS). (deepdyve.com)
Ester1
- Upon ingestion, psilocybin is converted, via hydrolysis of the phosphate ester, to psilocin (4-hy-droxy- N , N -di-methyl-tryptamine, C 12 H 16 N 2 O), which acts as an agonist of the serotonin (5-hy-droxy-tryptamine or 5-HT) 2A receptor, mediating its psychoactive effects. (iucr.org)
Organic anions1
- The process of secreting organic anions through the proximal tubule cells is achieved via unidirectional transcellular transport involving the uptake of organic anions into the cells from the blood across the basolateral membrane, followed by extrusion across the brush-border membrane into the proximal tubule fluid. (aspetjournals.org)
Superoxide1
- The FHA cycle is active inside the cell, detoxifying superoxide anion radicals (O2·-), which are mainly generated as a result of so-called 'electron leakage' to triplet oxygen (O2) in photosynthetic, mitochondrial, peroxisomal, and probably other electron transport chains (Ozyigit et al. (deepdyve.com)
Compounds4
- These are mixed anion compounds or mixed valence compounds. (wikipedia.org)
- Phosphate phosphites frequently occur as metal organic framework (MOF) compounds which are of research interest for gas storage, detection or catalysis. (wikipedia.org)
- Phosphate phosphite compounds are frequently produced by hydrothermal synthesis, in which a water solution of ingredients is enclosed in a sealed container and heated. (wikipedia.org)
- In soft tissues, phosphate is mainly found in the intracellular compartment as an integral component of several organic compounds, including nucleic acids and cell membrane phospholipids. (msdmanuals.com)
Abstract1
Excretion1
- To elucidate the molecular mechanisms for the tubular excretion of diuretics, we have elucidated the interactions of human organic anion transporters (hOATs) with diuretics using cells stably expressing hOATs. (aspetjournals.org)
Anionic1
- 1. Describe the anion or anionic complex that characterizes these non-silicate groups? (lsu.edu)
Lactate1
- However, glucose-6-phosphate is also the substrate for glycolysis and produces lactate. (medscape.com)
HOAT11
- These diuretics inhibited organic anion uptake mediated by hOAT1, hOAT2, hOAT3, and hOAT4 in a competitive manner. (aspetjournals.org)
Ligands1
- Host-guest interaction between cyclen based macrotricyclic ligands and phosphate anions. (univ-brest.fr)
Retention3
- Loss of glomerular function (associated with decreased glomerular filtration rate [GRF]) results in the retention of many end products of metabolism, including the anions of various organic and inorganic acids and urea. (medscape.com)
- The development of azotemia, anion retention, and acidosis is defined as uremic acidosis, which is not hyperchloremic. (medscape.com)
- The term hyperchloremic acidosis (ie, RTA) refers to a diverse group of tubular disorders, uncoupled from glomerular damage, characterized by impairment of urinary acidification without urea and anion retention. (medscape.com)
Acid3
- Intriguingly, the replacement of gluconate with ascorbate in the patch-clamp pipette reveals a large ascorbate efflux current, which shows sensitivity to the anion channel blocker, anthracene-9-carboxylic acid (A9C), indicative of the ascorbate release via anion channels. (deepdyve.com)
- This study aims to investigate the effects of a modified, balanced crystalloid including phosphate in a perioperative setting in order to maintain a stable electrolyte and acid-base homeostasis in the patient. (biomedcentral.com)
- The accumulation of lactic acid in blood can cause true acidosis with a large anion gap, a characteristic of glycogen-storage disease type I. (medscape.com)
Functional group1
- In the interaction with proteins, lead binds with virtually every available functional group, including sulfhydryl, amine, phosphate, and carboxyl groups, with sulfhydryl having the highest affinity. (cdc.gov)
Acidosis1
- The initial differentiation of metabolic acidosis should involve a determination of the anion gap (AG). (medscape.com)
Separation3
- High-performance chromatografic separation of inositol phosphate isomers on strong anion exchange columns. (chalmers.se)
- In this study, we develop an integrated process for the direct recovery and separation of dicalcium phosphate dihydrate for fertilizer and livestock feed additive production from a low-grade (2.0 wt% P) iron-rich (19.7 wt% Fe) phosphate ore. (rsc.org)
- Figure 1 shows the anion-exchange separation of components from the wash of an anode exhibiting 45% loss in capacity. (thermofisher.com)
Occur2
- Serious skin/hypersensitivity reactions such as Stevens-Johnson Syndrome, toxic epidermal necrolysis and erythema multiforme: Discontinue oseltamivir phosphate capsules and initiate appropriate treatment if allergic-like reactions occur or are suspected. (nih.gov)
- Phosphate depletion can occur in various disorders and normally results in conservation of phosphate by the kidneys. (msdmanuals.com)
Metabolism1
- Phosphate is also involved in aerobic and anaerobic energy metabolism. (msdmanuals.com)
Roles1
- Anion selective recognition plays pivotal roles in the environmental field. (rsc.org)
Uptake1
- Hepatic uptake carriers of the organic anion-transporting peptide (OATP) family of solute carriers are more and more recognized as being involved in hepatic elimination of many drugs and potentially associated drug-drug interactions. (aspetjournals.org)
Urinary2
Soluble1
- The main role of phosphate supplements is to deliver soluble and bioavailable phosphorus to plants and livestock as crop fertilizers or animal feed additives. (rsc.org)
Buffer2
- For anions, proprietary reagents were used, including the Anitron run buffer (PE Applied Biosystems, Foster City, CA, U.S.A.) and Micro-Coat capillary charge-reversal agent (PE Applied Biosystems), which was utilized to flush the capillary prior to each analysis. (unboundmedicine.com)
- Phosphate in bone serves as a reservoir, which can buffer changes in plasma and intracellular phosphate. (msdmanuals.com)
Processes1
- Most previous studies on the adoption of low-grade phosphate ores have focussed on ore beneficiation processes which are expensive, complex, and in some cases inefficient. (rsc.org)
Mmol1
- all concentrations in this formula are in mmol/L (mM or mEq/L) (see also the Anion Gap calculator). (medscape.com)
Oxygen1
- Most phosphorus in the body is complexed with oxygen as phosphate. (msdmanuals.com)
Enzyme1
Determination1
- Cell Technology's Phosphate detection kit provides a simple, one-step fluorimetric or colorimetric method for determination of phosphate in serum and plasma samples. (immunochemistry.com)
Interactions1
- Energy Decomposition Analysis (EDA) shows that the anion-receptor interactions are predominantly electrostatic. (rsc.org)
Phosphorus1
- Phosphorus supplements are usually produced from high-grade phosphate rock concentrates (28-40 wt% P 2 O 5 ). (rsc.org)
Chains1
Blood2
- Quantitation of phosphate anion in blood, plasma and serum samples. (immunochemistry.com)
- A related test, the anion gap blood test , checks whether your electrolytes are out of balance or if your blood is too acidic or not acidic enough. (medlineplus.gov)
Plasma1
- Phosphate is a major intracellular anion but is also present in plasma. (msdmanuals.com)
Form1
- 40% P 2 O 5 ), while livestock feed additives are usually in the form of dicalcium phosphate (CaHPO 4 ), monocalcium phosphate (Ca(H 2 PO 4 ) 2 ), or defluorinated phosphate (Ca 3 (PO 4 ) 2 ). (rsc.org)