Animals in toxicity testing animal testing alternatives. Medical search. Frequent questions

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Anatomy12

Cell Line Liver Cells, Cultured Cell Line, Tumor Kidney Brain Tumor Cells, Cultured Neurons Mitochondria HeLa Cells Lung Bone Marrow

Organisms12

Rats, Sprague-Dawley Mice, Inbred C57BL Mice, Inbred BALB C Escherichia coli Rats, Inbred F344 Rabbits Rats, Wistar Larva Cricetinae Dogs Daphnia Mice, Knockout

Diseases28

Neoplasms Drug-Related Side Effects and Adverse Reactions Leukopenia Radiation Injuries Drug-Induced Liver Injury Neutropenia Lung Neoplasms Hematologic Diseases Disease Models, Animal Breast Neoplasms Thrombocytopenia Body Weight Nausea Neurotoxicity Syndromes Neoplasm Metastasis Neoplasm Recurrence, Local Adenocarcinoma Gastrointestinal Diseases Stomatitis Plant Poisoning Vomiting Disease Progression Carcinoma, Non-Small-Cell Lung Colorectal Neoplasms Drug Eruptions Recurrence Abnormalities, Drug-Induced Prostatic Neoplasms

Chemicals and Drugs76

Antineoplastic Agents RNA, Messenger Protein Isoforms Cisplatin Fluorouracil Doxorubicin RNA Splice Sites Deoxycytidine Antineoplastic Agents, Phytogenic Antimetabolites, Antineoplastic Paclitaxel Cyclophosphamide Antidotes Recombinant Proteins RNA Precursors Camptothecin Plant Extracts Insecticides Antibodies, Monoclonal Carboplatin Water Pollutants, Chemical Teratogens Taxoids Environmental Pollutants Organoplatinum Compounds Etoposide DNA Glutathione Complement Factor B Leucovorin DNA, Complementary Methotrexate Vinblastine RNA-Binding Proteins Antineoplastic Agents, Alkylating DNA Primers Antibiotics, Antineoplastic Oxidoreductases Vincristine Complement C3 Bacterial Proteins Peptides Prodrugs Acetaminophen Drug Carriers Drug Combinations Enzyme Inhibitors Nuclear Proteins Ifosfamide Cadmium Aluminum Bacterial Toxins Anti-Bacterial Agents Dacarbazine Neurotoxins Methylmercury Compounds Amyloid beta-Peptides Antioxidants Reactive Oxygen Species Recombinant Fusion Proteins Antibodies, Monoclonal, Humanized Proteins Dihydrouracil Dehydrogenase (NADP)L-Lactate Dehydrogenase Complement C3 Convertase, Alternative Pathway Transcription Factors Xenobiotics Cytochrome P-450 CYP2E1 Liposomes Thiazoles Bleomycin Nerve Tissue Proteins RNA Topotecan Herbicides Membrane Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment70

Toxicity Tests Toxicity Tests, Acute Animal Testing Alternatives Treatment Outcome Lethal Dose 50 Antineoplastic Combined Chemotherapy Protocols Drug Administration Schedule Toxicity Tests, Chronic Complementary Therapies Infusions, Intravenous Administration, Oral No-Observed-Adverse-Effect Level Combined Modality Therapy Maximum Tolerated Dose Survival Analysis Drug Evaluation Models, Biological Drug Evaluation, Preclinical Disease-Free Survival Survival Rate Toxicity Tests, Subchronic Radiotherapy Dosage Cloning, Molecular Follow-Up Studies Polymerase Chain Reaction Retrospective Studies Reverse Transcriptase Polymerase Chain Reaction Disease Models, Animal Reproducibility of Results Prospective Studies Feasibility Studies Body Weight Radiotherapy Organ Size Area Under Curve Sequence Alignment Neoplasm Staging Gene Expression Profiling Models, Genetic Phytotherapy Clinical Trials as Topic Transfection Injections, Intravenous Dose Fractionation Drug Delivery Systems Sensitivity and Specificity Toxicity Tests, Subacute Remission Induction Radiotherapy, Conformal Drug Therapy, Combination Sequence Analysis, DNA Blotting, Western Drug Carriers Salvage Therapy Models, Molecular Clinical Trials, Phase I as Topic Radioimmunotherapy Pilot Projects Risk Assessment Biological Assay Chromatography, High Pressure Liquid Models, Statistical Radiotherapy, Intensity-Modulated Chemotherapy, Adjuvant Oligonucleotide Array Sequence Analysis Analysis of Variance Mutagenicity Tests Dose-Response Relationship, Radiation Injections, Intraperitoneal Genetic Therapy

Phenomena and Processes60

Alternative Splicing Complement Pathway, Alternative Dose-Response Relationship, Drug Lethal Dose 50 Exons Base Sequence Time Factors Amino Acid Sequence Cell Survival No-Observed-Adverse-Effect Level Maximum Tolerated Dose Mutation RNA Splice Sites Introns RNA Splicing Tissue Distribution Transcription, Genetic Apoptosis Gene Expression Regulation Protein Binding Drug Interactions Species Specificity Kinetics Complement Activation Body Weight Organ Size Gene Expression Area Under Curve Oxidative Stress Signal Transduction Algorithms Transfection Cell Death Genetic Vectors Drug Synergism Promoter Regions, Genetic Structure-Activity Relationship Sensitivity and Specificity Organ Specificity Sequence Homology, Amino Acid Molecular Structure Phenotype Biotransformation Protein Structure, Tertiary Binding Sites Particle Size Oxidation-Reduction Pregnancy Polyadenylation Larva Drug Resistance, Neoplasm Phylogeny Metabolic Detoxication, Drug Complement Pathway, Classical Reproduction Evolution, Molecular Cell Proliferation Half-Life Dose-Response Relationship, Radiation Drug Resistance

Disciplines and Occupations3

Toxicology Toxicogenetics Computational Biology

Technology, Industry, Agriculture3

Nanoparticles Metal Nanoparticles Liposomes

Information Science9

Molecular Sequence Data Base Sequence Amino Acid Sequence Survival Rate Algorithms Radiotherapy, Conformal Computer Simulation Phylogeny Radiotherapy, Intensity-Modulated

Health Care19

Treatment Outcome Survival Analysis Radiation Injuries Disease-Free Survival Survival Rate Follow-Up Studies Retrospective Studies Reproducibility of Results Prospective Studies Feasibility Studies Area Under Curve Clinical Trials as Topic Sensitivity and Specificity Clinical Trials, Phase I as Topic Pilot Projects Risk Assessment Models, Statistical Analysis of Variance Dose-Response Relationship, Radiation

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Technology, Industry, Agriculture Information Science Health Care

Alternative Splicing Toxicity Tests Toxicity Tests, Acute Animal Testing Alternatives Complement Pathway, Alternative Dose-Response Relationship, Drug Treatment Outcome Molecular Sequence Data Lethal Dose 50 Exons Antineoplastic Combined Chemotherapy Protocols Drug Administration Schedule Antineoplastic Agents Toxicity Tests, Chronic Complementary Therapies Base Sequence Time Factors Amino Acid Sequence Neoplasms RNA, Messenger Cell Survival Infusions, Intravenous Protein Isoforms Administration, Oral Cisplatin Fluorouracil Cell Line No-Observed-Adverse-Effect Level Combined Modality Therapy Maximum Tolerated Dose Doxorubicin Mutation Liver Cells, Cultured Toxicology RNA Splice Sites Introns RNA Splicing Drug-Related Side Effects and Adverse Reactions Survival Analysis Deoxycytidine Antineoplastic Agents, Phytogenic Drug Evaluation Models, Biological Antimetabolites, Antineoplastic Leukopenia Cell Line, Tumor Radiation Injuries Paclitaxel Drug-Induced Liver Injury Drug Evaluation, Preclinical Neutropenia Tissue Distribution Cyclophosphamide Disease-Free Survival Antidotes Recombinant Proteins RNA Precursors Lung Neoplasms Survival Rate Camptothecin Rats, Sprague-Dawley Plant Extracts Toxicity Tests, Subchronic Radiotherapy Dosage Cloning, Molecular Insecticides Antibodies, Monoclonal Follow-Up Studies Transcription, Genetic Carboplatin Hematologic Diseases Mice, Inbred C57BL Polymerase Chain Reaction Water Pollutants, Chemical Teratogens Apoptosis Retrospective Studies Reverse Transcriptase Polymerase Chain Reaction Gene Expression Regulation Taxoids Disease Models, Animal Breast Neoplasms Thrombocytopenia Environmental Pollutants Organoplatinum Compounds Etoposide Kidney DNA Glutathione Complement Factor B Leucovorin Protein Binding DNA, Complementary Drug Interactions Species Specificity Reproducibility of Results Methotrexate Kinetics Prospective Studies

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