Animals developed metabolic. Medical search. Frequent questions

Supported by researchers and investigators, UNSW aims to address these disorders and develop new treatments and strategies. (edu.au)
UNSW research in metabolism and metabolic disorders has undergone considerable growth in scope and output, producing high impact publications and secured national competitive grants. (edu.au)
Notably, UNSW School of Biotechnology & Biomolecular Sciences Professor Rob Yang carried out extensive research into metabolic disorders with a breakthrough discovery in the transportation of cholesterol in cells. (edu.au)
Porphyrias are a group of rare metabolic disorders characterized by red and purple pigments accumulating in the body. (keene.edu)
eating disorders also occur in animals when stress and fear inhibit feeding. (sciencebasedmedicine.org)
Recent insight suggests that an altered composition and diversity of gut microbiota could play an important role in the development of metabolic disorders. (frontiersin.org)
Metabolic syndrome is one of the most common disorders in industrialized countries. (druglib.com)
Metabolic and Bariatric Surgery Metabolic and bariatric (weight-loss) surgery alters the stomach, intestine, or both to produce weight loss in people have obesity or overweight and have metabolic disorders related to obesity. (msdmanuals.com)
However, for most people, taking multivitamins does not appear to reduce risk of developing cancer or heart or blood vessel (cardiovascular) disorders. (msdmanuals.com)
The overall purpose of our research is to develop novel strategies for the prevention and treatment of diabetes and related metabolic disorders. (lu.se)
To elucidate the role of brain hormone-sensitive lipase in the development of metabolic and neurodegenerative disorders. (lu.se)

No prospective studies have evaluated the associations between different types of plant-based diets and incident metabolic syndrome (MetS) and components of MetS. (unboundmedicine.com)
Wild dragonflies infected with parasites become obese and develop a form of metabolic syndrome. (sciencebasedmedicine.org)
In studying the immunological mechanisms that underlie metabolic control of fat tissue, Yair Reisner, of the Weizmann Institute of Science in Israel, and his colleagues discovered that mice that lacked certain dendritic immune cells that release a toxic molecule called perforin progressively gained weight and exhibited features of the metabolic syndrome. (sciencedaily.com)
The findings indicate that perforin-expressing dendritic cells are critical for protecting against metabolic syndrome and autoimmunity, and shifting the abundance of these cells in relation to other immune cell populations may help prevent or treat such conditions. (sciencedaily.com)
It is hard to predict how this might impact patient care, but we should initially try to find if the absence of this rare subpopulation of cells is associated with obesity, metabolic syndrome, or any autoimmune or other immune abnormalities," Reisner says. (sciencedaily.com)
Diet-induced obesity in C57BL/6 mice triggers common features of human metabolic syndrome (MetS). (scienceopen.com)
In conclusion Ecd has beneficial effects on fat and muscle tissue and may be able to prevent the metabolic syndrome and sarcopenia by a non-estrogenic mechanism. (ironmagazine.com)
Metabolic syndrome consists of a group of co-occuring conditions that increase an individual's risk of developing heart disease, stroke, and diabetes. (druglib.com)
The purpose of this study is to evaluate the long-term effectiveness of chloroquine, a protein-activation medication, at reducing the progression of atherosclerosis in patients with the metabolic syndrome. (druglib.com)
The syndrome substantially increases the risk of developing diabetes and vascular disease, but there is no clear unifying approach to treat this disorder. (druglib.com)
In animals, activation of the protein ataxia telangiectasia mutated (ATM) using the antimalarial drug chloroquine improves features of metabolic syndrome and decreases atherosclerosis, a build-up of fatty plaque within arteries. (druglib.com)
The purpose of this study is to examine the effect of long-term treatment with low doses of chloroquine on atherosclerosis in people with metabolic syndrome. (druglib.com)
Hence, many effects of nutrition on the development and progression of cancer lack 'specificity' in their association, and such alimentary cues also affect the risk of developing metabolic syndrome, a prelude to arteriosclerosis and neurodegeneration ( Fig. 1 ). (nature.com)
We leverage modern techniques of functional genomics, epigenetics, transcriptomics, proteomics, gene editing and model-driven experimentation to understand the underlying causes of atherosclerosis and metabolic syndrome and discover therapeutic targets. (yale.edu)
Our work involves population and family-based genetic studies, high throughput sequencing to identify disease genes, with a focus on coronary artery disease (CAD) and metabolic syndrome (MetS). (yale.edu)
These groundbreaking achievements have made us one of the leading laboratories in investigation of metabolic syndrome. (yale.edu)
One of our groundbreaking discoveries was the identification of founder mutations in the DYRK1B gene, underlying atherosclerosis, metabolic syndrome, and fatty liver disease. (yale.edu)
People who become infected with this virus often exhibit relatively mild or no symptoms, but some will develop a form of hemorrhagic fever with renal syndrome (HFRS) with death in approximately 1-2% of HFRS cases. (cdc.gov)

Our researchers are currently looking to combat metabolic diseases such as cardiovascular disease, fatty liver disease, obesity, type 2 diabetes and cancer. (edu.au)
Changing the mix of gut bacteria in mice prevented those destined for obesity from gaining weight and fat or developing related metabolic problems linked to insulin resistance - but only if the mice ate a healthy diet - a new study from Washington University School of Medicine in St. Louis has found. (ausfoodnews.com.au)
This is important as we look to develop next-generation probiotics as a treatment for obesity," he said. (ausfoodnews.com.au)
In both men and women, central obesity is associated with increased levels of insulin and with disruption of normal endocrine and metabolic functions. (britannica.com)
It is known that rats treated, at neonatal age, with monosodium L-glutamate (MSG) develop neuroendocrine and metabolic abnormalities, resulting in a phenotype of hypothalamic obesity, characterized by increased adiposity, corticosteronemia and leptinemia. (nel.edu)
Postmenopausal women develop often obesity which may be prevented by 20-OH-Ecdysone (Ecd). (ironmagazine.com)
Animal and human epidemiological studies have established that sub-optimal maternal diet throughout pregnancy results in offspring that are at increased risk of later metabolic disease including diabetes and obesity. (nottingham.ac.uk)
Although not all studies are unanimous [ 11 - 13 ], most agree that this type of training is also a time-effective alternative to MICT, leading to higher weight loss, particularly visceral fat mass, and better improvement of the metabolic profile and cardiorespiratory fitness in people with obesity [ 14 - 16 ]. (hindawi.com)

We have strong expertise in the fields of lipid and glucose metabolism and use state-of-the art techniques to better understand how altering cellular metabolism impacts metabolic diseases. (edu.au)
With the accidental discovery that the skin color of the flatworm Schmidtea mediterranea (S. mediterranea) changes under prolonged exposure to sunlight, these animals could provide a new model for studying the diseases. (keene.edu)
She began to wonder whether animals got other human diseases. (sciencebasedmedicine.org)
The pathogens from animal diseases can adapt to humans, as in the case of HIV. (sciencebasedmedicine.org)
White adipose tissue (WAT) - a key contributor in many metabolic diseases - contributes about one fourth of a healthy human's body mass. (nature.com)
Understand these changes is important to predict diseases and develop therapies. (frontiersin.org)
A new theory suggests that gut microbiota contribute to the regulation of energy homeostasis, provoking the development of an impairment in energy homeostasis and causing metabolic diseases, such as insulin resistance or TDM2. (frontiersin.org)
The metabolic endotoxemia, modifications in the secretion of incretins and butyrate production might explain the influence of the microbiota in these diseases. (frontiersin.org)
On another floor is Paradigm Therapeutics, which plans to extend the genomics-driven research on the central nervous system and metabolic diseases that it does at its UK home in Cambridge. (newscientist.com)
As a result, nutrition affects the incidence, natural progression and therapeutic response of malignant diseases, both in humans and in preclinical animal models. (nature.com)
Because of the abrupt onset of uremia, patients are usually well fleshed, have glossy well groomed hair coats, and pink mucous membranes in contrast to animals with chronic diseases and chronic renal failure. (vin.com)
The group comprises faculty that span across multiple disciplines with research focuses in basic and translational research and with implications for animal health and diseases and the environment. (umd.edu)
We carry out translational gene therapy studies targeting several neurological and metabolic diseases. (umassmed.edu)
In addition to targeting specific diseases, we develop therapeutic platforms based on molecular approaches such as genome editing and RNA-based methods. (umassmed.edu)
Since the beginning of the pandemic, researchers such as Holger Volk, PhD, chair of small animal diseases at the University of Veterinary Medicine in Hannover, Germany, have been investigating whether dogs can recognize SARS-CoV-2 infections. (medscape.com)
This programme will entail collection, analysis, interpretation and exchange of appropriate information on animal and human populations at risk of disease, on animal husbandry practices and the environment, as well as on the impact of these diseases on human and animal health and national economy, which will assist in determining the cost-effectiveness of surveillance and control programmes. (who.int)
Policies and plans for implementation of the global and regional exchange of information and surveillance of diseases of common interest should be developed by WHO with FAO and the Office international des Epizooties . (who.int)
In collaboration with FAO and the Office international des Epizooties , WHO should update and review existing lists of reportable diseases common to humans and animals. (who.int)
Other zoonotic diseases such as rabies, brucellosis and bovine tuberculosis (caused by Mycobacterium bovis ) have been controlled or eliminated in several industrialized countries, but remain endemic in developing regions. (who.int)

Renal Tubular Defects in Small Animals The form of metabolic acidosis that occurs in acute kidney injury and Stages 2-4 of chronic kidney disease, referred to as uremic acidosis, is due to reduced urine-acidifying ability of diseased. (merckvetmanual.com)
The excretory failure is identified by rapid (hours to days) increases in BUN, serum creatinine and phosphate, and variable hyperkalemia and metabolic acidosis. (vin.com)
The classic laboratory profile is an early osmolar gap that later transitions to an anion gap metabolic acidosis. (medscape.com)

If the animals ate a healthy diet low in saturate fat and high in fruits and vegetables, microbes from the lean twin invaded the gut of the mouse with the obese twin's microbes, preventing weight gain and the development of metabolic problems associated with insulin resistance. (ausfoodnews.com.au)
In humans, insulin resistance is associated with significant weight gain and typically is the first sign of metabolic problems that eventually can lead to diabetes. (ausfoodnews.com.au)

In line with its desire to provide innovative solutions to meet the sustainability challenges facing farms and animal sectors, METEX NØØVISTAGO has developed a unique combination of natural ingredients specially selected and scientifically tested for the functional and synergetic roles they play in animal metabolism. (metabolic-explorer.com)
DO-SRS microscopy enables us to probe de novo lipogenesis in animals, image protein biosynthesis without tissue bias, and simultaneously visualize lipid and protein metabolism and reveal their different dynamics. (nih.gov)
Efficient Metabolism: Xerocoles often have lower metabolic rates, which helps them conserve energy and reduce water loss through respiration. (desertusa.com)
We have developed expertise in in vivo investigation of lipid and glucose metabolism, insulin secretion and sensitivity, and vascular biology and in human physiological studies, leading to discovery of attractive drug targets that have been either patented or being investigated for their utility in treatment of fatty liver disease and diabetes in 2 clinical trials in the outlier populations of Fars/Iran. (yale.edu)
Faculty in our nutrient utilization and metabolism group study the uptake, transport and fate of nutrients in animals, the nutritional requirements of animals, and procedures for minimizing nutrient loss to the environment. (umd.edu)
The Nutrient Utilization and Metabolism faculty possess expertise in both basic and applied research approaches to systemically address important nutritional issues facing animal agriculture at the local, state and national levels. (umd.edu)
It is in this context that Marx's central concepts of the "universal metabolism of nature," "social metabolism," and the metabolic "rift" have come to define his critical-ecological worldview. (monthlyreview.org)

Here we discuss the molecular mechanisms through which alimentary cues modulate metabolic, microbial and neuroendocrine circuitries and thus affect the probability of developing premalignant lesions that progress to clinically manifested disease and the response to therapeutic intervention. (nature.com)

T2DM - the most prevalent form of diabetes - often develops during chronic positive energy balance, e.g., by a combination of excessive energy intake and physical inactivity 1 , 2 . (nature.com)
Next, they fed the mice a high fat diet, causing the animals to develop diabetes. (newswise.com)
For patients with diabetes, alert dogs recognize a dangerous metabolic state before clinical symptoms develop. (medscape.com)

Additionally, in vivo metabolic responses to intravenous high glucose load were performed in, 24 hour-fasting, CT and TP rats. (nel.edu)
We use a unique combination of nanotechnology , animal model development and in vivo imaging to better understand the mechanism and progression of cellular and metabolic conditions that lead to perinatal brain injury, with a focus on autism and cerebral palsy. (hopkinsmedicine.org)

The first area involves the identification and evaluation of a new generation of probiotic bacterial strains that can be used to promote metabolic health. (lu.se)
Bacterial strains with potentially beneficial properties are screened in different cell lines and primary cells, after which the most promising strains are evaluated further in animal models and eventually in clinical trials. (lu.se)

Over a median follow-up of 8 years, 2,583 participants developed incident MetS. (unboundmedicine.com)
By recruiting more than thousand kindreds with early onset CAD and multiple metabolic risk factors for genetics and metabolic studies we have been able to map, identify and characterize a dozen of human disease genes for CAD and MetS, which have been reported in leading journals such as Nat Genet, Science, NEJM, Cell Metab, JCI, PNAS, AJHG, etc. (yale.edu)

BioRestorative Therapies, Inc. ( www.biorestorative.com ) develops therapeutic products using cell and tissue protocols, primarily involving adult stem cells. (biospace.com)
The Sujatha Kannan Lab works to develop therapeutic strategies for preventing perinatal brain i ... njuries from occurring during development. (hopkinsmedicine.org)

In the new study, scientists observed that mice lacking a particular type of immune cell gained excess weight and developed metabolic abnormalities even when they consumed a standard diet. (sciencedaily.com)
Depleting these T cells prevented the mice that lacked the perforin-expressing dendritic cells from gaining weight or developing metabolic abnormalities. (sciencedaily.com)
Animal models of genetically determined ALS exhibit pathological abnormalities long predating clinical deficits. (bmj.com)

Public health officials and others concerned with appropriate actions to take at hazardous waste sites may want information on levels of exposure associated with more subtle effects in humans or animals (LOAELs) or exposure levels below which no adverse effects (NOAELs) have been observed. (cdc.gov)
Bio-calorimeter system to measure the metabolic rate of laboratory animals after inhalation exposure to toxic materials. (cdc.gov)
Breathing rates in addition to metabolic rates were measured pre-exposure, immediately post-exposure and 18 hours post-exposure. (cdc.gov)
Food (particularly from animals) is the major source of exposure for humans. (pops.int)
No studies were located regarding systemic effects in animals after inhalation exposure to tetryl. (cdc.gov)
The immediately dangerous to life or health (IDLH) airborne concentration values developed by the National Institute for Occupational Safety and Health (NIOSH) characterize these high-risk exposure concentrations and conditions [NIOSH 2013]. (cdc.gov)
A physiologically based pharmacokinetic (PBPK) model for iodomethane was developed to characterize poten- tial human health effects from iodomethane exposure. (cdc.gov)

Notably, mice lacking these regulatory dendritic cells were also found to be more prone to develop another form of autoimmunity with symptoms similar to those found in multiple sclerosis," Reisner adds. (sciencedaily.com)
After sudden caffeine cessation, withdrawal symptoms develop in a modest number of cases but are typically moderate and transient. (medscape.com)
People who become infected with this virus often exhibit relatively mild or no symptoms, but some develop HFRS ( https://www.cdc.gov/hantavirus/hfrs ), which can result in death in approximately 1-2% of HFRS cases. (cdc.gov)

BAT is intended to mimic naturally occurring brown adipose depots that regulate metabolic homeostasis in humans. (biospace.com)
Two years ago, the international research team first demonstrated that adipose tissue offers beneficial metabolic effects in response to exercise. (newswise.com)

Direct visualization of metabolic dynamics in living animals with high spatial and temporal resolution is essential to understanding many biological processes. (nih.gov)
It comprises a variety of tools ranging from high-resolution anatomical structure visualization to functional studies and even molecular-level description of metabolic events in the cell. (lu.se)

Biochemical, cellular, and tribological analyses are undertaken to establish the metabolic fate and influence of the novel vegetable oil derivatives. (usda.gov)
As such, the Department's research programs extend beyond traditional areas of animal science and include investigation into the molecular, cellular and biochemical basis of animal reproduction and development. (umd.edu)
Faculty in our genetics and cell biology group investigate the genetic basis for animal growth, disease resistance, and nutrient efficiency, and the mechanisms underlying nutrient uptake, cellular differentiation, and lipid secretion. (umd.edu)

As compensatory mechanisms are not fully developed in pediatric patients, the clinical signs need to be dealt with as quickly as possible. (ivis.org)
Despite its significance, many WAT-related pathophysiogical mechanisms in humans are still not understood, largely due to the reliance on non-human animal models. (nature.com)

Many animals with compensated and asymptomatic chronic renal insufficiency sustain subtle insults (e.g., fever, concomitant disease, vomiting, diarrhea, congestive heart failure, drug administration), which precipitate a seemingly acute uremic crisis (designated A acute-on-chronic@ renal failure). (vin.com)
During early December 2016, a home-based rat breeder in Wisconsin developed an acute febrile illness. (cdc.gov)

In energy homeostasis, not only does WAT act as the main storage site of excess dietary energy (Fig. 1c ), it also performs crucial endocrine and metabolic functions (Fig. 1d ) 7 , 8 . (nature.com)

Using renewable raw materials, the company develops and industrialises innovative and competitive industrial fermentation processes as alternative to petrochemical processes to meet consumers' new societal expectations and the objectives of the energy transition. (metabolic-explorer.com)
Their immune system and many of the metabolic processes are not fully developed yet. (ivis.org)

In dogs, supplementation with oral calcium during pregnancy may predispose the animal to eclampsia during peak lactation, because excessive calcium intake during pregnancy causes downregulation of the calcium regulatory system and subsequent clinical hypocalcemia when calcium demand is high. (merckvetmanual.com)
Students are trained in molecular cell biology, drug discovery/development, animal physiology, pharmacology and pre-clinical disease models. (edu.au)
The overt clinical ALS phenotype may develop when safety margins are exceeded subsequent to years of mitochondrial dysfunction, neuroinflammation or an imbalanced environment of excitation and inhibition in the neuropil. (bmj.com)

In contrast, intense visible light altered their coloring, with just over half of them developing one or more small tissue lesions. (keene.edu)
The animals also had an altered collection of T immune cells residing in their fat tissue. (sciencedaily.com)
High-quality images of small animals and excised tissue can be obtained. (lu.se)

To find out if the protein promoted beneficial metabolic effects, they treated the mice with TGF beta 2. (newswise.com)
The experiment showed a number of positive metabolic effects in the mice, including improved glucose tolerance and increased fatty acid uptake. (newswise.com)
To know if TGF beta 2 was actually responsible for the metabolic effects, they treated the diabetic mice with TGF beta 2. (newswise.com)
While the connection between fat cells and inflammation has already been shown in mice fed a high-fat diet, this is the first time that researchers have demonstrated the connection in animals on a regular diet, simply by eliminating perforin-expressing dendritic cells. (sciencedaily.com)
Mice fed low-fat mouse food and given gut microbes from an obese twin gained weight and fat and took on the metabolic dysfunction of the donor, while mice given gut microbes from a lean twin stayed lean. (ausfoodnews.com.au)
The researchers showed that weight gain, accumulation of fat and development of metabolic problems were only prevented in mice that had "obese" microbes if they ate healthy diets. (ausfoodnews.com.au)
When the animals were fed a typical "unhealthy" diet - high in saturated fat and low in fruits and vegetables - there was no colonisation of "lean" microbes into the guts of mice carrying microbes from an "obese" twin. (ausfoodnews.com.au)
These mice gained weight and fat and developed metabolic problems. (ausfoodnews.com.au)

Eliminate risk of animal or viral infectious agents in cell cultures. (pharmaceutical-business-review.com)
The NITD is plugging into the country's strengths in infectious disease research by concentrating on developing new treatments for dengue fever and tuberculosis. (newscientist.com)

Initial preclinical research indicates that increased amounts of brown fat in animals may be responsible for additional caloric burning as well as reduced glucose and lipid levels. (biospace.com)

The results of the high glucose load 90-min test indicated that TP and CT rats developed similar glycemia but this accounted because of an early significantly higher peak values of circulating insulin in TP than in CT rats, regardless of similar enhancement in circulating glucocorticoid concentrations in both groups. (nel.edu)
While high glucose load significantly increased, over the baseline, circulating leptin concentrations as early as 30 min post-glucose in CT rats, in TP animals, it significantly enhanced leptinemia only by the end of the test. (nel.edu)
Baseline testing includes carotid artery intimal-medial thickness, carotid MRI, lipid panel, complete blood count, comprehensive metabolic chemistry panel, Thyroid-stimulating hormone (TSH) and glucose tolerance test with plasma insulin and glucose responses. (druglib.com)

Within the broad vibrational spectra of C-D bonds, we discover lipid-, protein-, and DNA-specific Raman shifts and develop spectral unmixing methods to obtain C-D signals with macromolecular selectivity. (nih.gov)
Developed by bioprocess engineers to improve cell culture performance and to enhance protein production while maintaining cell viability. (pharmaceutical-business-review.com)

Pretty much every human disorder occurs in animals too. (sciencebasedmedicine.org)

This new knowledge can be applied to developing drugs that will boost good cholesterol and alleviate the risk of heart disease and stroke in the years to come. (edu.au)
Teenage risk-taking behavior is paralleled in young animals undergoing the transition to adult life. (sciencebasedmedicine.org)
However, several factors have been identified that increase the risk of developing pancreatic cancer. (britannica.com)
Through our new collaboration, we together have made a commitment to help protect people around the world who are at risk of developing dengue virus disease. (merck.com)
Occupational health professionals have employed these values beyond their initial purpose as a component of the NIOSH Respirator Selection Logic to assist in developing risk management plans for nonroutine work practices governing operations in high-risk environments (e.g., con- fined spaces) and the development of emergency preparedness plans. (cdc.gov)
In addition, animal-associated infections (caused by, for example, Toxoplasma gondii , Listeria monocytogenes ) have been reported in people at increased risk because of deficiencies in the normal immune response as a result of immunosuppressive drugs, cancer or HIV infection. (who.int)

Everything from gambling to compulsive shopping can be viewed in terms of beneficial animal activities like foraging and hunting. (sciencebasedmedicine.org)
Our results are important because it's really the first demonstration of an exercise-released adipokine that can have beneficial metabolic effects on the body," says Goodyear. (newswise.com)

No group differences were found in basal circulating levels of several hormones and metabolic parameters. (nel.edu)
The model enabled calculation of human equivalent con- centrations (HECs) to the animal no-observed-adverse-effect levels (NOAELs) using chemical-specific parameters to determine the internal dose instead of default assumptions. (cdc.gov)

GO and KEGG analysis showed that genes regulated by E2 and/or HFD are mainly responsible for immune response, inflammatory response and metabolic pathways. (scienceopen.com)

A sexually transmitted disease in animals can become a human disease where infection is by ingestion, like brucellosis. (sciencebasedmedicine.org)
It is essential that most of the dragon's food (especially livefood) first be dusted with a phosphorus-free commercial calcium supplement, as bearded dragons are susceptible to Metabolic Bone Disease (MBD) if their calcium and vitamin D3 requirements are not met. (wikibooks.org)
KENILWORTH, N.J.-( BUSINESS WIRE )-Merck (NYSE:MRK), known as MSD outside the United States and Canada, and Instituto Butantan, Sao Paulo, Brazil, a non-profit producer of immunobiologic products for Brazil today announced a collaboration agreement to develop vaccines to protect against dengue virus disease, the mosquito-borne infection. (merck.com)
Each disease changes individual metabolic steps in the body, which is a topic of research in metabolomics. (medscape.com)

Behavioral Adaptations: Some xerophilic animals exhibit behavioral adaptations to survive in arid environments. (desertusa.com)
Mouse models with genetic or pharmacological inhibition of hormone-sensitive lipase are studied using a battery of metabolic and behavioral tests. (lu.se)

We can now add porphyria to this growing list, with plans to use the animals to screen for novel therapies in the near future. (keene.edu)

Laboratory animals given dioxins suffered a variety of effects, including an increase in birth defects and stillbirths. (pops.int)
neutron radiation (in cinogenicity in laboratory animals. (who.int)

INNEUS ® plays a key role in keeping animals' digestive and immune systems working properly and improves their general health and well-being. (metabolic-explorer.com)

Animal studies shed light on human erectile dysfunction and premature ejaculation. (sciencebasedmedicine.org)
Human drug addicts are not alone: animals seek and respond to chemical rewards in the lab and in the wild. (sciencebasedmedicine.org)
Lessons learned from reducing the weight of obese pets and zoo animals might inform human dieting efforts. (sciencebasedmedicine.org)
No human or live animal testing is needed. (usda.gov)
The animals in this experiment were fed "healthy" or "unhealthy" human diets. (ausfoodnews.com.au)
Subsequent molecular and physiological studies in human mutation carriers and animal models have allowed us to unravel novel functions of the identified genes, to delineate their cognate pathways and to discover new targets for pharmaceutical intervention. (yale.edu)
In this study, we report the full sequence and analysis of pCT and demonstrate the spread of pCT-like plasmids in animal and human E. coli isolates from the United Kingdom, Europe, Australia, and Asia. (cdc.gov)
Human and animal health officials are working together to trace-back from where infected rodents may have come, and trace-out where potentially infected rodents may have been distributed, and make sure infected rats are not distributed further. (cdc.gov)

Research also links PCBs to reproductive failure and suppression of the immune system in various wild animals, such as seals and mink. (pops.int)

Develop standardized methods and protocols for collecting, processing, and archiving samples obtained from live animals and teach collaborating researchers protocols. (nist.gov)
To assess the animals' performance, the researchers collected real-world data from 2802 attendees at four concerts. (medscape.com)

Its functional ingredients of natural origin are used in the formulation of cosmetic products, nutrition-animal health or as intermediates for the synthesis of biomaterials. (metabolic-explorer.com)
New products will be developed that improve the health and safety of the American public, extend the shelf life of consumer products, and provide biobased alternatives and substitutes for petroleum-based chemicals. (usda.gov)
Pacific Marine Mammal Health Assessments (PMMHA) allow monitoring and sample collection and biobanking from individual living animals in U.S. Pacific Islands marine mammal populations. (nist.gov)
Assess environmental and anthropogenic stressors along with metabolic changes that may impact health of individuals and U.S. Pacific Islands marine mammal populations. (nist.gov)
No other health effects were studied in animals. (cdc.gov)
Alison is responsible for developing the curriculum, learning materials and assessments for the pharmacology components of the post- graduate non-medical prescribing programme run as a distance or attended route.The course is available to a range of health care professionals including nurses, midwives, physiotherapists and podiatrists. (nottingham.ac.uk)
Central to the mission of most veterinary public health organizations and services are the needs to assess and manage animal-related public health risks and to communicate these risks to the parties concerned. (who.int)
To identify novel probiotic strains with the ability to promote metabolic health. (lu.se)
Our research will contribute to the development of a new generation of probiotic strains that can be used to preserve metabolic health. (lu.se)

They are a group of organisms that are environmentally important, such as saprophytes and mutualists, but are pathogens for animals, especially plants. (intechopen.com)
Complete DNA sequences can be used as a platform to develop rapid epidemiologic tools to identify and trace the spread of plasmids in clinically relevant pathogens, thus facilitating a better understanding of their distribution and ability to transfer between bacteria of humans and animals. (cdc.gov)

This reversed the negative metabolic effects of the high fat diet, similar to what happens with exercise. (newswise.com)
This research really revolutionizes the way we think about exercise, and the many metabolic effects of exercise. (newswise.com)
These relationships can all be interpreted in the light of the 'unopposed estrogen' hypothesis, which proposes that endometrial cancer may develop as a result of the mitogenic effects of estrogens, when these are insufficiently counterbalanced by progesterone. (scienceopen.com)
Metabolic effects of 20-OH-ecdysone in ovariectomized rats. (ironmagazine.com)

Their research developed from the unexpected observation by undergraduate students that the flatworms they were investigating changed color from brown to white when exposed to sunlight for several days. (keene.edu)
The research animals are to be housed in a vast complex in the basement. (newscientist.com)
This agreement recognizes the tremendous progress that scientists and clinicians at the Instituto Butantan have made in developing their investigational dengue virus vaccine," said Dr. Roger M. Perlmutter, president, Merck Research Laboratories. (merck.com)

Pediatric patients are not just small versions of the adult animals. (ivis.org)
We found that neonatal androgenization induced adult animals displaying higher visceral adiposity mass, body weight and leptinemia than CT rats. (nel.edu)

The amino acids produced by fermentation meet the precise nutritional requirements of animals. (metabolic-explorer.com)

The animals Seidlova-Wuttke uses for her experiments have had their ovaries removed, so they produce very low levels of sex hormones. (ironmagazine.com)

NAMs for chemical hazard assessment are often evaluated in comparison to animal studies. (nih.gov)
In animal studies, modest doses of the ecdysteroid 20-hydroxy-ecdysone [structural formula shown below] increased the muscle mass of rats and also reduced the amount of body fat. (ironmagazine.com)
Few data exist from animal studies with tetryl. (cdc.gov)

Metabolic rate of animals can be affected by a variety of toxic agents. (cdc.gov)
The calorimeter system provides non-invasive, reproducible results which can be used to evaluate an animal's metabolic response to toxic materials. (cdc.gov)

This can be seen in sick animals that are anorectic for prolonged periods but also in grazing animals in arid regions with low phosphorus content in soil. (merckvetmanual.com)
The desert biome is home to a unique array of animals that have evolved remarkable adaptations to survive in the harsh conditions of arid regions. (desertusa.com)

self-injury also occurs in animals and probably represents grooming gone awry. (sciencebasedmedicine.org)
The ability and frequency with which antimicrobial resistance genes disseminate between bacteria in humans, the environment, and animals is still debated, and the role of plasmids in this movement between ecosystems, including the food chain, is also still contested, despite mounting evidence that it occurs ( 8,9 ). (cdc.gov)

Instead, embryos from the high-altitude region used less energy to complete development, that is, they developed faster without a concomitant increase in metabolic rate, compared with those from the low-altitude region. (lu.se)

We develop chemical and biochemical systems for the conversion of seed oils to value-added specialty/commodity chemicals. (usda.gov)

The fennec fox of North Africa has large ears which Schwartz points out "serve a dual purpose": they are great for listening for bugs to eat that may be moving around underground, but they are also loaded with blood vessels, allowing the animals to dissipate excess body heat. (mentalfloss.com)

Join us as we explore the incredible adaptations of these animals in the desert. (desertusa.com)
Some animals may have adaptations that allow them to survive in the desert, but they may also be found in other habitats and environments. (desertusa.com)
So, while xerocoles are specialized desert dwellers with specific adaptations, not all desert animals fall exclusively into this category. (desertusa.com)
There is a spectrum of adaptations and habitat preferences among the animal species found in desert ecosystems. (desertusa.com)
To learn more about desert animals and their unique adaptations, explore the links below. (desertusa.com)

Disorders11

Syndrome18

Obesity8

Diseases19

Acidosis3

Insulin resistance2

Metabolism7

Neuroendocrine1

Diabetes3

Vivo2

Bacterial2

MetS2

Therapeutic2

Abnormalities3

Exposure7

Symptoms3

Adipose2

Visualization2

Cellular3

Mechanisms2

Acute2

Homeostasis1

Processes2

Clinical3

Tissue3

Mice8

Infectious2

Preclinical1

Glucose3

Protein2

Disorder1

Risk6

Beneficial2

Parameters2

Inflammatory1

Disease4

Behavioral2

Therapies1

Laboratory2

Improves1

Human8

Immune system1

Researchers2

Health9

Pathogens2

Effects4

Research3

Adult animals2

Nutritional requirements of animals1

Experiments1

Studies3

Toxic2

Arid regions2

Occurs2

Development1

Biochemical1

Excess1

Adaptations5