Animal testing regulations. Medical search. Frequent questions

However, under the European Chemicals Agency ECHA's REACH regulation 1907/2006 , certain aspects require or enable animal testing - notably testing for environmental endpoints like aquatic toxicity, the pre-registration of some new chemical substances and registering of chemicals used in non-cosmetic products. (cosmeticsdesign-europe.com)
The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). (europa.eu)
EOGRTS was introduced under Commission Regulation (EU) 2015/282 of 20 February 2015 amending Annexes VIII, IX and X to the REACH Regulation (EC No. 1907/2006). (europa.eu)
It is a test method developed to assess the reproductive toxicity of chemical substances and is the preferred test method to address the standard information requirement defined in Column 1 of Point 8.7.3 of Annexes IX and X to the REACH Regulation instead of the Two-Generation Reproductive Toxicity study. (europa.eu)
There are no Specific Rules for Adaptation from Column 1 in Annex X Section 8.7 of the REACH Regulation, but these are in place for the test at Annex IX. (europa.eu)
The requirement to conduct complex mammalian toxicity tests at Annex IX which potentially involves the use of hundreds of vertebrates (normally rats) needs to be carefully considered to ensure that it satisfies Article 25(1) of the REACH Regulation that any testing on vertebrate animals is undertaken only as a last resort. (europa.eu)

Experiments on vertebrate animals in the European Union are since January 1, 2013. (wikipedia.org)
Furthermore, according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort. (europa.eu)

Clinique pays third-party companies to test their ingredients and finished products.Clinique does not have PeTa, Leaping Bunny, or Choose Cruelty Free certifications. (caringconsumer.com)
On 12 November 2013, we wrote to all the companies on the Choose Cruelty Free List in relation to the issue of animal testing in China. (choosecrueltyfree.org.au)

In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. (europa.eu)
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided. (europa.eu)
The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment. (europa.eu)
The relevant criterion relating to the principle of proportionality is the result of balancing the different objectives pursued by Regulation No 1907/2006 and the application of the precautionary principle. (europa.eu)

All licensed establishments must have an Animal Welfare and Ethical Review Body (commonly referred to as AWERBs) which considers and monitors project applications for the site. (wikipedia.org)
The German Animal Welfare Act, 1972, is designed to enforce the utilitarian principle that there must be good reason for one to cause an animal harm and identifies that it is the responsibility of human beings to protect the lives and well-being of their fellow creatures. (wikipedia.org)
The Animal Welfare Act is supplemented by the Animal Protection Laboratory Animal Regulations, 2013, and the European Directive 2010/63/EU. (wikipedia.org)
We prioritise animal welfare in our work. (bprc.nl)
But sadly because these overseas markets offer lucrative investment opportunities to major brands, many still continue to overlook animal welfare in exchange for bigger profits. (choosecrueltyfree.org.au)
Caterina is a Veterinary student at the University of Cambridge with a real passion for animal welfare. (frame.org.uk)
At L'Oréal, we care for animal welfare and do not test on animals. (target.com)
This database, created in 2000, is updated every three months with newly published scientific articles, books, and other publications related to improving or safeguarding the welfare of animals used in research. (awionline.org)
Journal of Applied Animal Welfare Science 25(4), 362-367. (awionline.org)
The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. (awionline.org)
Animal Welfare 29(1), 69-80. (awionline.org)
Deflighting zoo birds is a practice that receives increasing criticism due to its presumed incompatibility with animal welfare. (awionline.org)
It's Okay to Cry - Discussions by the Laboratory Animal Refinement & Enrichment Forum [LAREF], Volume V. Animal Welfare Institute, Washington, DC. (awionline.org)
In contrast, animal advocates emphasize the importance of public debate and awareness of the reality of research animals to improve animal welfare and to work towards an end of animal experimentation. (brill.com)
and reports on finished projects from an animal welfare point of view. (brill.com)

Estée Lauder's animal testing policy states they eliminated animal testing over 30 years ago, but are still not certified cruelty-free. (caringconsumer.com)

The kinetic direct peptide reactivity assay (kDPRA) is a modification of the DPRA (OECD TG 442C) wherein the reaction kinetics of a test substance towards a synthetic cysteine-containing peptide is evaluated. (iivs.org)
In a notice issued on March 22, the NMPA drafted acceptance of nine test methods including: Direct Peptide Reaction Assay (DPRA) for Skin Sensitization (OECD TG 442C) Short Time Exposure Assay (STE) for eye irritation (OECD TG 491) These new regulations will go into effect January. (iivs.org)
Following the methodology described in OECD Test Guideline 497, KeratinoSens is an alternative to animal testing methods necessary for the purpose of hazard identification. (iivs.org)
Analysis of the relevance and adequateness of using Fish Embryo Acute Toxicity (FET) Test Guidance (OECD 236) to fulfil the information requirements and addressing concerns under REACH. (ufz.de)
For example, testing according to OECD Technical Guideline 236 (fish embryo acute toxicity test (FET)) has been suggested as one of the alternative methods to toxicity testing in adult fish. (ufz.de)
The Extended One-Generation Reproductive Toxicity Study (EOGRTS) (OECD TG443, EU B.56) in its basic test design is a standard information requirement at REACH Annex IX (where concerns regarding reproductive toxicity are evident) and X levels. (europa.eu)
Bioaccumulation is assessed on the partition coefficient (n-octanol/water), usually reported as log K ow (also log P ow ) where substances with log K ow ≥ 4.5 are assessed as having a high potential for bioaccumulation (OECD test 107 or 117). (janusinfo.se)

Pan-Asian regulatory expert Dr Tommy Kong outlines current cosmetic import regulations in China . (choosecrueltyfree.org.au)
To assist in the eradication of bovine tuberculosis, farmers and ranchers should adhere to animal import regulations, require TB testing of new cattle before purchase, maintain permanent identification of animals, keep records of animal movements into and out of their herd, prevent contact of breeding cattle with cattle of unknown origin, and cooperate with government officials on TB investigations. (ca.gov)
This report summarizes initial descriptive epidemiologic, clinical, and laboratory data, interim infection-control guidance, and new animal import regulations. (cdc.gov)

The amendment does not prohibit companies to use animal testing to fulfill regulatory requirements in other countries. (wikipedia.org)
During a 2002 House of Lords select committee inquiry into animal testing in the UK, witnesses stated that the UK has the tightest regulatory system in the world, and is the only country to require a cost-benefit assessment of every licence application. (wikipedia.org)
Speaking to CosmeticsDesign-Europe, Dr Mojgan Moddaresi, regulatory expert and director of cosmetics compliance firm Personal Care Regulatory, said when it came to chemical safety assessment within cosmetics, it would be important industry looked to animal alternatives wherever possible. (cosmeticsdesign-europe.com)
To assess whether and how exposure to chemical substances can impact our health and the environment, European and national regulatory authorities rely on the results from several testing methods, including animal testing, when performing their safety assessment. (env-health.org)
All stakeholders involved in chemical regulatory discussions share the long-term goal of moving away from animal testing. (env-health.org)
As long as alternative methods validated and accepted for regulatory use are not available, and without the full implementation of a precautionary approach, animal tests are the only viable way to assess whether or not a chemical is hazardous to our health or the environment. (env-health.org)
Today, European and national regulatory authorities assess the safety of chemicals on the basis of a variety of information, including scientific literature as well as tests performed in vivo (on living organisms such as rodents, fish, amphibians), in vitro on isolated cells or tissues, and increasingly in silico (using computer models). (env-health.org)
That is why non-animal approaches such as in vitro tests cannot be used on their own to meet regulatory definitions of certain endpoints. (env-health.org)
Despite PETA's efforts -and the efforts of the thousands of PETA members who responded to our pleas to "defend animals from Environmental Defense"-EDF continues to push regulatory agencies to institute its massive animal testing plans. (peta.org)
The aim of this study was to assess the capacity of the FET test in predicting acute fish toxicity and to define the applicability domain of the FET test for regulatory purposes. (ufz.de)
Animal testing in China is under constant regulatory review and we'll do our utmost to keep you abreast of the changes as and when they occur. (choosecrueltyfree.org.au)
Examples include the care and feeding of any animals associated with research activities and maintaining research property used for regulatory science research such as high performance computational equipment. (hhs.gov)
c) References in this part and parts 12, 13, 14, 15, and 16 to regulatory sections of the Code of Federal Regulations are to chapter I of title 21 unless otherwise noted. (fda.gov)

This was ominous for the laboratory animals as it would mean even more products would be animal-tested, even if they were sold via e-commerce channels. (choosecrueltyfree.org.au)
The projects are judged not only on their potential to impact the reduction or replacement of laboratory animals, but also on the quality of the application and the feasibility of the project. (frame.org.uk)
On target animals and in laboratory animals. (hartz.com)

Animal testing regulations are guidelines that permit and control the use of non-human animals for scientific experimentation. (wikipedia.org)
According to animal experimentation statistics, fish are the second most commonly used group of animals in research after mice. (phys.org)
Rabbits and rodents are the animals most frequently victim to experimentation. (one-voice.fr)

This is the 5th volume of selected discussions that took place on the electronic Laboratory Animal Refinement & Enrichment Forum between February 2016 and December 2019. (awionline.org)

With regard to Estée Lauder, Clinique's parent company, the company has been collaborating with Cruelty Free International in their fight to end the practice of testing products on animals since 2019. (caringconsumer.com)
Gaithersburg, MD - May 8, 2019 - The Institute for In Vitro Sciences, Inc. (IIVS) has received a grant from the European Partnership for Alternative Approaches to Animal Testing (EPAA) to support its annual training of Chinese scientists in non-animal testing methods. (iivs.org)
Gaithersburg, MD - April 3, 2019 - The Institute for In Vitro Sciences (IIVS) applauds China's National Medical Products Administration (NMPA) for their acceptance of certain non-animal (alternative) test methods for the regulation of cosmetics. (iivs.org)
However, adaptions pursuant to Annex XI (General Rules for Adaptation of the Standard Testing Regime set out in Annexes VII to X) and a recent Judgement of the General Court in Case T-755/17 (September 2019) in relation to the Principle of Proportionality are considered relevant to the potential for adaption of this test requirement in appropriate instances. (europa.eu)

However, China's National Medical Products Administration (NMPA) confirmed that as of 1st May 2021, they may exempt some cosmetics brands from their compulsory animal testing requirements. (caringconsumer.com)
We'll have to wait and see if Clinique and Estée Lauder will be exempted from China's animal testing regulations. (caringconsumer.com)
We are pleased to share that today China's National Medical Products Association (NMPA) has approved new methods for the regulations of cosmetics. (iivs.org)
China's National Institutes for Food and Drug Control (NIFDC) published a bulletin on the potential adoption of two non-animal methods of cosmetics testing. (choosecrueltyfree.org.au)

While animals, largely mice, remain extensively used for medical research and testing, the European Union implemented a ban on all animal testing for cosmetic products and cosmetics ingredients under its Cosmetics Regulation 1223/2009 in 2013. (cosmeticsdesign-europe.com)
The Ministry of Health is attempting to bring its cosmetics laws in correspondence with the Cosmetics Regulation of the European Union. (invitrointl.com)

The European Union must invest more in next-generation, non-animal chemical safety assessments to achieve its European Green Deal goals, and there are opportunities in in silico methods, says Cruelty Free Europe. (cosmeticsdesign-europe.com)
A drive to better understand all the chemicals we are exposed to must be underpinned by investment in scientifically sound non-animal hazard testing methods, exposure monitoring methods and risk assessment strategies. (cosmeticsdesign-europe.com)
"If REACH and ECHA would like to reduce animal testing in industry, they should reduce the bureaucracy in approving new alternative methods for evaluating the chemical safety," she said. (cosmeticsdesign-europe.com)
Why is animal testing still being used for chemical safety testing today, while alternative methods already exist and more are being developed? (env-health.org)
While the skin sensitization hazard of substances can readily be identified using non-animal methods, the classification of potency into UN GHS sub-categories 1A and 1B remains challenging. (iivs.org)
Additionally, the bill includes funding for the development of alternative test methods. (iivs.org)
It also promotes alternative methods for the hazard assessment of substances in order to reduce the number of tests on animals. (europa.eu)
EDF representatives are behind the times and so narrowly focused on animal testing that they have missed the boat entirely on the new era of modern non-animal testing methods . (peta.org)
As the U.S. government now recognizes and the Nature article states, high-capacity non-animal methods are the only possible way to test tens of thousands of chemicals. (peta.org)
EDF is supporting a bipartisan chemical-testing reform bill called the Frank R. Lautenberg Chemical Safety for the 21st Century Act , which would modernize the way chemicals are tested and regulated in the U.S. and encourage the use of cutting-edge non-animal test methods. (peta.org)
AIDS, malaria, hepatitis, tuberculosis and autoimmune diseases such as MS. At the same time, we also expend a great deal of energy on the development of testing methods that do not involve animal testing. (bprc.nl)
BPRC researchers are working hard to develop methods which will help us preserve endangered species in an animal-friendly manner. (bprc.nl)
For this reason, BPRC is very active in the development of alternative methods which do not involve animal testing. (bprc.nl)
EU Health Commissioner Tonio Borg has urged Chinese authorities to follow the European example and rid the cosmetics arena of animal testing and turn to alternative methods instead . (choosecrueltyfree.org.au)
In the 21st century, we may be able to advance past animal testing with the help of computer modeling and advanced cell-based methods. (acdlabs.com)
According to the Ministry, Ukraine has not officially endorsed any alternative testing methods that are considered viable. (invitrointl.com)
InVitro International (IVRO), headquartered in Placentia, CA was established in September 1985 and is a customer and technology driven provider of non-animal testing methods. (invitrointl.com)

5) Any declaration under this section shall include a description of the eradication area, or part of it, the name of the disease on which the declaration is based and the list of the species of aquatic animals and carcasses or parts of carcasses of those aquatic animals that are susceptible to that disease. (gc.ca)
In her project, she used bioinformatics (computer-based technology and tools for analysing and understanding biological data) to collate and analyse available biological data to identify specific physiological differences between animal species and the impact this has on their response to different drugs. (frame.org.uk)
It is well known that differences in physiology and metabolism between species is responsible for causing differences in how animals respond to drugs - a mouse may not behave in the same way as a dog, or a human. (frame.org.uk)
It is also well publicised, and often required in the guidelines, that the most relevant species is used in specific tests. (frame.org.uk)
Yet sometimes the regulations also require tests on a second species of animal, often a larger mammal such as a dog. (frame.org.uk)
Tools that help understand or assess the relevance of a species and their similarity to humans could help streamline this process of species selection, or rejection in pharmaceutical research and testing. (frame.org.uk)
Her project made use of bioinformatics to analyse the primary protein structure of different target cells for three named drugs within eight different animal species, including humans, mice, dogs, cows and rabbits. (frame.org.uk)
Veterinary healthcare is the science involved with the diagnosis, prevention and treatment of the disease covering a broad variety of species both in wild and domestic animals. (emailwire.com)
Few people who live in countries where animal experiments occur know much detail about the numbers and species of animals used, the types of procedures they endure, or the pain and suffering involved ( Hadley, 2012 ), as well as the ineffectiveness of using animals as models for humans. (brill.com)
overcrowding and mixing of various animal species. (cdc.gov)

But if the tests are poor predictors of human cancer, then regulation of exposure to chemicals rests on quicksand. (independent.org)
REACH is the most important regulation in the chemical area, requiring all manufacturers and importers of chemicals in quantities above 1 ton/year to register the substances. (estiv.org)
While all stakeholders engaged on chemicals share the goal to progressively eliminate tests performed on animals and core pieces of EU legislation on chemicals refer to this goal, it is unfortunately currently not possible to fully do without them for several reasons that are detailed further below. (env-health.org)
However, in vitro tests alone do not allow us to assess complex adverse effects that chemicals may have on an organism, for example, effects on the brain or the metabolism across generations. (env-health.org)
The Batteries Regulation aims to make batteries sustainable throughout their life cycle, and to protect citizens and the environment from risks of harmful chemicals in batteries. (europa.eu)
REACH is a regulation of the European Union, adopted to improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemicals industry. (europa.eu)
PETA wrote to the Environmental Defense Fund (EDF) because it was one of the chief architects and is largely responsible for initiating the Environmental Protection Agency's (EPA) notorious high production volume (HPV) chemical-testing program , which was created to pressure chemical manufacturers to test (or retest) thousands of chemicals using an arbitrary "checklist" of crude, painful, and uninformative animal tests. (peta.org)
Continuing to depend on unreliable animal tests won't result in the regulation of dangerous chemicals any more than it has up until now. (peta.org)
It is conducted as part of the registration of (industrial) chemicals under European regulations as well as other regulations. (ufz.de)
The same is true when it comes to testing, whether it's chemicals or pharmaceuticals. (acdlabs.com)

EDF officials on expert panels have testified that the maximum amount of animal testing should be undertaken regardless of the ineffectiveness of these tests. (peta.org)

We are equally committed to consumer health and safety, and bringing to market products that comply with applicable regulations in every country in which our products are sold. (caringconsumer.com)
To comply with the regulation, companies must identify and manage the risks linked to the substances they manufacture and market in the EU. (europa.eu)

During the presentation we will describe both regulations and we will guide participants through the database of the European Chemical Agency (ECHA) where all the studies performed for registering chemical substances are stored. (estiv.org)
The well-respected authors of the article recommended a pause in a massive European animal testing program known as REACH (Registration, Evaluation, and Authorization of Chemical Substances) so that non-animal alternatives for reproductive toxicity testing could be developed and incorporated. (peta.org)

As of today, using non-animal approaches such as in vitro tests on cells might be informative regarding certain elements of this definition, for instance to elucidate the endocrine mode of action of a chemical. (env-health.org)
In conjunction with other in vitro tests, the results of this assay. (iivs.org)

As "Guardians of the Galaxy Vol. 3 "lights up the box office, its glow is reaching animals who are rarely seen: those in laboratories. (phys.org)
European regulation has had little effect on motivating French laboratories to change their stance on animal testing. (one-voice.fr)

The science of product testing and toxicology led to massive increases in product safety over the course of the 20th century. (acdlabs.com)
In this episode, we're going to be talking about the role of chemical predictions in toxicology and product testing. (acdlabs.com)
and there is a strong ethically-driven trend for moving towards non-animal-based techniques in toxicology," he explained. (fil-idf.org)

After previous unsuccessful attempts by physicians to elicit from the patient and his wife a history of animal exposure, on October 12, the wife reported that the patient had had recent contact with a bat. (cdc.gov)
As infected animals and contaminated environments are the primary source of human infections, regional analyses that bring together surveillance data from human and animal health sectors are an important basis for exposure and transmission risk assessment and public health action. (who.int)

Currently, the rules require all deer entering the state to be accompanied by a veterinarian's statement that the animals are free of evidence of contagious and communicable diseases, and further require all imported animals to have been tested in accordance with any applicable regulations of the Texas Animal Health Commission. (texas.gov)

Must not test their ingredients, formulations, or finished products on animals. (caringconsumer.com)
Although, once these ingredients were integrated into cosmetic formulations, further animal testing was prohibited. (cosmeticsdesign-europe.com)

Since 2009 for some endpoints and 2013 as a general rule, the Cosmetic Regulation has banned new in vivo tests of both finished cosmetics and cosmetic ingredients. (estiv.org)

Asia Pacific Strategy for Emerging Diseases and Public Health Emergencies (APSED III): Advancing implementation of the International Health Regulations (2005). (who.int)

POTUS signed my bill to end mandatory animal testing into law. (localsyr.com)
In China, it is mandatory for cosmetics to be tested on animals before they are sold. (caringconsumer.com)
Hong Kong still has no mandatory animal testing regulations for e-commerce or retail. (choosecrueltyfree.org.au)

This resistance to antimicrobial medicines is happening in all parts of the world for a broad range of pathogens, with an increasing prevalence that threatens human and animal health. (who.int)

If animal cancer tests are reasonably accurate in predicting the probability, sites, and severity of human cancers, then regulation of carcinogens is on firm ground. (independent.org)
The use of human-relevant models must be put to use in our drug development programs for the benefit of patients, drug sponsors, and animals. (localsyr.com)
Rand Paul: Why Is the FDA Still Requiring Human or Animal Testing For New Drugs? (reason.com)
The Food and Drug Administration (FDA) activities funded through user fees will continue including the regulation and testing of human and animal drugs, biosimilars, medical devices, and tobacco products. (hhs.gov)
You can never make an animal that you're testing human relevant enough. (acdlabs.com)
Research with captive wildlife in Animal Biosafety Level 2 (ABSL2) and 3 (ABSL3) facilities is becoming increasingly necessary as emerging and re-emerging diseases involving wildlife have increasing impacts on human, animal, and environmental health. (awionline.org)
But why is transparency in non-human animal (hereinafter referred to as animal) research desirable, or indeed vital? (brill.com)
Civets have been considered one of the most likely ani- immunofluoresence antibody assay (IFA) and quantified in mals responsible for animal-to-human SARS-CoV trans- a microtiter virus neutralization test (VNT). (cdc.gov)
Pre-clinical phase (around 2 years): Testing of the vaccine on non-human subjects (e.g. isolated cells and animal models) to determine if the vaccine safely produces immunity. (addisonindependent.com)
Clinical development phase (5-9 years): Following FDA approval, researchers enter the three consecutive sub-phases of the clinical development phase, in which the vaccine is tested on an increasing number of human subjects. (addisonindependent.com)
Animal Rights in Medical Research As the declaration of human right states that all human beings are free and equal in dignity and rights. (majortests.com)
The indirect impact of antimicrobial resistance, however, extends beyond increased health risks and encompasses economic losses due to reduced productivity caused by sickness (of both human beings and animals) and higher costs of treatment. (who.int)
Drug-resistant bacteria can circulate in populations of human beings and animals, through food, water and the environment, and transmission is influenced by trade, travel and both human and animal migration. (who.int)
Form a multisectoral country task force (with ToRs) to detect, verify and manage events and threats at the animal-human-environmental interface, following a One Health approach and bringing together relevant sectors at the national and subnational levels. (who.int)
Thylakoid membranes derived from green leaf chloroplasts affect appetite-regulating hormones, suppress food intake, reduce blood lipids and lead to a decreased body weight in animals and human subjects. (lu.se)
However, on October 18, rabies was diagnosed by the direct fluorescent antibody (DFA) test from postmortem brain samples tested by the Houston Department of Health and Human Services. (cdc.gov)
From November 2003, when a resurgence of H5N1 virus activity in humans and animals occurred, through September 2017, 1,838 human infections with avian influenza viruses in the region were reported to WHO. (who.int)
Hammond A, Fitzner J, Collins L, Ong S, K V. Human cases of influenza at the human-animal interface, January 2015-April 2017. (who.int)
Cyanobacteria , blue-green algae, are recommended for effects testing of antimicrobials in environmental risk assessments according to the European guidelines for risk assessment of medicinal products for human use (EMEA/CHMP/SWP/4447/00 corr 2). (janusinfo.se)
Research on dementia , life support drugs and serious injuries requires testing on human subjects who are not always capable of making their own decisions. (lu.se)

In the United States, animal tests are not a legal requirement. (caringconsumer.com)
Just like most subsidiaries under the parent company Estée Lauder, Clinque also sells products in China where animal testing is a legal requirement. (caringconsumer.com)
For instance, under the EU regulation on classification, labelling and packaging (CLP) regulation, the identification of hazards such as carcinogenicity, endocrine disruption, or reproductive toxicity includes the requirement for positive evidence coming from tests performed in vivo . (env-health.org)
Imported products can continue to be direct mailed by foreign companies to consumers in the Chinese mainland for personal use with no animal testing requirement. (choosecrueltyfree.org.au)
Imported products can be sent to Hong Kong by foreign companies, then an agent there can direct mail to consumers in the Chinese mainland for personal use, with no animal testing requirement. (choosecrueltyfree.org.au)

The CLP (classification, labelling and packaging) Regulation contains rules for the classification, labeling and packaging of chemical products. (janusinfo.se)

The assessment of severity has also changed under the amendments to the Animals (Scientific Procedures) Act (1986). (wikipedia.org)
The assessment of severity must also be conducted retrospectively, which results in severity being assigned on the basis of the actual suffering experienced by the animals, rather than what is presumed during study design. (wikipedia.org)

One of these proposed tests (a 90-day oral toxicity study that is not even required in the HPV chemical program) would involve repeatedly poisoning animals for three months, while the other (a reproductive toxicity test) would cause the suffering and deaths of more than 900 animals. (peta.org)
EDF argued against the partial animal testing moratorium, going so far as to state that "only" 2,600 animals would be killed for each reproductive toxicity test conducted, rather than the 3,200 suggested by the authors of the Nature article! (peta.org)

Recent actions by Texas Animal Health Commission (TAHC) in prohibiting the importation of elk, white-tailed deer, mule deer, and black-tailed deer from the States of Colorado and Nebraska, and the loss of Texas' TB-Free status highlight the importance of cervid diseases to livestock raisers in Texas. (texas.gov)

Analyses with terminal restriction fragment length polymorphism and principal component analysis of faeces demonstrated different microbial populations in the thylakoid- and control-fed animals. (lu.se)

With a 2004 amendment to the Cosmetics Directive, the animal testing for cosmetic products is forbidden in the EU. (wikipedia.org)
The amendment also prohibited, since 11 March 2009, to market cosmetic products containing ingredients which have been tested on animals. (wikipedia.org)
As far as cruelty-free goes, Clinique claims their products and ingredients are not tested on animals. (caringconsumer.com)
Must not permit suppliers or manufacturers to test their ingredients or finished products on animals. (caringconsumer.com)
Must not pay third-party companies to test their ingredients or finished products on animals. (caringconsumer.com)
Must not contain animal products. (caringconsumer.com)
Clinique allows suppliers to test ingredients and products where animal testing is required by law. (caringconsumer.com)
In 2013, the European Union prohibited beauty brands from selling products and ingredients that have been tested on animals. (caringconsumer.com)
The company's products are sold in China and other countries where testing products and ingredients on animals is required by law. (caringconsumer.com)
We do not conduct animal testing on our products or ingredients, nor ask others to test on our behalf, except when required by law. (caringconsumer.com)
We evaluate our finished products in clinical tests on volunteer panels. (caringconsumer.com)
The move followed an initial ban on testing for finished products in 2004 and ingredients in 2009. (cosmeticsdesign-europe.com)
we won't accredit any company that allows their products to be animal tested, anywhere in the world. (choosecrueltyfree.org.au)
In countries such as China (mainland) regulations require that most imported cosmetic products must undergo animal testing prior to being sold retail to consumers. (choosecrueltyfree.org.au)
For the animals in question this means a miserable and often shortened existence as these products are tested in the name of safety regulations. (choosecrueltyfree.org.au)
Since 1989, we have not tested the safety of our products on animals, 14 years before regulations required us to do so. (target.com)
There are effective non-animal ways to ensure the safety of cosmetic products. (target.com)
The blue and orange One Voice label clearly marks products that have not been tested on animals- and they are even vegan! (one-voice.fr)
The nation may be the next country in line to completely ban testing cosmetic products on animals, if trends continue in the direction that the government has recently set. (invitrointl.com)
However, EPA-monitored flea and tick products are tested and monitored just as rigorously since all of the products under their watch can be sold over the counter directly to the consumer. (hartz.com)
Resistant bacteria can be found in food animals and food products destined for consumption by humans. (who.int)

Texas Parks and Wildlife regulates the importation of white-tailed and mule deer under the provisions of Scientific Breeder Permit regulations. (texas.gov)

Since the establishment of a world fur market in the early modern period , furs of boreal , polar and cold temperate mammalian animals have been the most valued. (wikipedia.org)

Martina's project looked at the use of Non-Technical Summaries (NTSs) to sustain the Replacement, Reduction and Refinement of animal use in Respiratory Disease Research. (frame.org.uk)
2021. Animal-centric Care and Management - Enhancing Refinement in Biomedical Research. (awionline.org)

Also animal testing for cosmetic ingredients is prohibited since March 2009. (wikipedia.org)
In addition to that, cosmetic ingredients are governed by the EU's Cosmetic Regulation, which is focused on the protection of consumers when using cosmetics. (estiv.org)
In a recent study, we demonstrated that this is not fully true, as many cosmetic ingredients are being tested in vivo for REACH purposes ( https://doi.org/10.14573/altex.2104221 ). (estiv.org)
We will also explain the conflict between the two regulations regarding the possibility to test cosmetic ingredients on animals, by presenting the results of our analysis. (estiv.org)
Among the in new in vivo tests performed on cosmetic ingredients, some were necessary for REACH compliance, but others should have been avoided. (estiv.org)
One of the new technical regulations on cosmetics will increase the list of banned ingredients by a factor of three. (invitrointl.com)

However, the increasing regulations on antibodies coupled with the rising costs of animal testing are likely to restrain the market growth to some extent. (emailwire.com)
All of the farms tested had obtained markets had higher rates of antibodies to SARS-CoV than their original seed stock from markets. (cdc.gov)

This is not just because of improved hygiene, but is also largely due to breakthroughs in the medical industry, e.g. drugs and vaccines that were developed during this century, often partially due to animal testing. (bprc.nl)
In preclinical research, animals are used to predict safety and efficacy of new drugs prior to clinical trials on people. (frame.org.uk)

Rob Taalman, science and research director of Cosmetics Europe, recently said next-generation in vitro safety assessments for cosmetics would see good uptake in the coming years , though, becoming accepted by regulators and public alike as "robust and powerful" alternatives to animal studies. (cosmeticsdesign-europe.com)
However, completely getting rid of animal tests for chemical safety assessments overnight would constitute a serious threat to our health as well as wildlife. (env-health.org)

The best projects also have the potential to inform or impact current animal research practices, regulations, or education now and in the future. (frame.org.uk)
Thus, the only way to counter the damage done to the animal research community's public image is to increase the lay community's understanding of research practices" (O'Sullivan, 2006, p. 6). (brill.com)

Our scientific research institute is located in Rijswijk and employs more than one hundred people, ranging from animal care workers and animal behaviour experts to vets and geneticists. (bprc.nl)

Important progress is currently being made in the development of in vitro and in silico tests, but they will not be fit to address the complexity of the assessment of adverse effects on organisms before a long time. (env-health.org)

Comprehensively explains animal learning theories and current best practices in animal training within zoos. (awionline.org)

All animals have the capacity to learn through operant conditioning and other types of learning, and as a result, zoos and other animal care facilities have shifted towards the use of positive reinforcement training to. (awionline.org)
Animal performers are all around, from on TV to zoos and circuses. (majortests.com)

EU Regulations are legislative acts that are immediately implemented in all 27 member states of the European Union. (estiv.org)
In this Q&A, the Health and Environment Alliance (HEAL) answers several key questions about the use of animal testing in the European Union. (env-health.org)
If future efforts move forward in the wake of the current announcement, European Union standards will serve as the basis of the Ukrainian norms in terms of regulation. (invitrointl.com)

As part of the agreement, two scientists from BASF SE, a member of EPAA, will join IIVS to provide hands-on training in China for four non-animal approaches for skin sensitization. (iivs.org)

Now that the FDA Modernization Act 2.0 has become law, it is time for the FDA to amend its regulations," said Dr. Neil Wilcox, board president of the Center for Responsible Science and former Senior Science Policy Officer, Office of Science at the FDA. (localsyr.com)
6598 looks to amend a number of the Ukraine's laws to better match EU standards on animal abuse. (invitrointl.com)
Petition means a petition, application, or other document requesting the Commissioner to establish, amend, or revoke a regulation or order, or to take or not to take any other form of administrative action, under the laws administered by the Food and Drug Administration. (fda.gov)

The FDA is supposed to no longer mandate animal-testing for new pharmaceuticals. (localsyr.com)

All research involving humans and animals must be tried by the Ethical Review Board. (lu.se)

Among the laws in the regulation is a stoppage on cosmetic testing on animals. (invitrointl.com)
Animal rights laws apply to all sorts of animals from dogs to farm animals. (majortests.com)

Animal abuse," "preparing dogs to go hunting", and "injury of animals" are new phrases that are making their way through the legislative branch with punishments attached to them. (invitrointl.com)
CDC has received reports of patients with a febrile rash illness who had close contact with pet prairie dogs and other animals. (cdc.gov)

REACH Regulation6

Vertebrate animals2

Choose Cruelty Free2

19074

Welfare15

Certified cruelty-free1

OECD7

Import regulations3

Regulatory13

Laboratory animals3

Experimentation3

20161

20194

China's4

Cosmetics Regulation2

Methods17

Species10

Chemicals10

Undertaken1

Comply2

Chemical substances2

Vitro tests2

Laboratories2

Toxicology3

Exposure2

Applicable regulations1

Formulations2

Endpoints1

INTERNATIONAL HEALTH REGU1

Mandatory3

Pathogens1

Human20

Requirement5

Classification1

Severity2

Reproductive toxicity2

Diseases1

Populations1

Products21

Permit1

Mammalian1

Refinement2

Ingredients6

Antibodies2

Drugs2

Assessments2

Research practices2

Vets1

Organisms1

Practices1

Zoos2

European Union3

Approaches1

Amend3

Pharmaceuticals1

Humans and animals1

Laws2

Dogs2