Animal experimentation on research into cancer. Medical search. Frequent questions

Written by Richard Miller , emeritus professor of Pharmacology, "The Rise and Fall of Animal Experimentation" details the history of animal experimentation - from its early beginnings in the 17th century through present day - citing diverse scientific, theological and philosophical bases for its use. (northwestern.edu)
The workshop will bring together a group of scholars representing a broad range of disciplinary expertise--from the history of neurology and neuroscience to food culture and health, global cancer research, the impact of pharmaceutics on society, epidemics, medical ethics, and the history of animal experimentation--to finalize chapters for a forthcoming edited volume, "Cultural History of Medicine, 1920-2000, The Modern and Postmodern Age," to be published by Bloomsbury Publishing. (nyu.edu)

Certain animal rights groups have acted out with violence against people who believe that animal experimentation is not a bad thing. (123helpme.com)
I generally believe that animal experimentation is a morally flawed way to accumulate scientific knowledge. (freakonomics.com)

The use of animals in some forms of biomedical research remains essential to the discovery of the causes, diagnoses, and treatment of disease and suffering in humans and in animals. (stanford.edu)
It is important to stress that 95% of all animals necessary for biomedical research in the United States are rodents - rats and mice especially bred for laboratory use - and that animals are only one part of the larger process of biomedical research. (stanford.edu)
Our researchers are strong supporters of animal welfare and view their work with animals in biomedical research as a privilege. (stanford.edu)
There are many outreach and advocacy organizations in the field of biomedical research. (stanford.edu)
The focus will be on human health and biomedical applications using computational models, animal models or human experimentation. (frontiersin.org)
Using an integrated platform of metabolic labeling, high-resolution mass spectrometry and computational analysis, we report here a comprehensive dataset of the in vivo half-life of 3,228 and the expression of 8,064 cardiac proteins, quantified under healthy and hypertrophic conditions across six mouse genetic strains commonly employed in biomedical research. (nature.com)
Miller discusses important cutting-edge alternatives to the use of animals in biomedical research and examines the utility of animal research through a scientific lens. (northwestern.edu)
The project led by Jana Selent , a PI on the research programme of biomedical informatics, aims to identify antiviral drugs that interfere with the lifecycle of SARS-CoV-2 by preventing its entry into cells. (prbb.org)
Undoubtedly, animal experimentation has played a central role in biomedical research throughout history, where animals were first used as models of anatomy and physiology. (ommegaonline.org)
It became the first published book to advocate creating "induced animal models" for biomedical research, by proposing the use of chemical and physical induction of disease in animals. (ommegaonline.org)
And so began a conversation both enlightening and enraging, detailing Dr. Chandrasekera's journey as a biomedical scientist growing increasingly disenchanted by the system within which she works, specifically due to the use of animal models in research. (unboundproject.org)
This strategy allows the establishment of a revolutionary concept of disease models for experimental biomedical research. (eceae.org)
Applications of these models are countless, and so are the benefits which they brought to biomedical research within the past ten years. (eceae.org)
With a longstanding interest in biomedical research and a passion for better understanding one of the least regenerative organs in the body, the lung, he has spent the past four years helping to uncover some of the mechanisms that may drive a lung disease currently without a cure, idiopathic pulmonary fibrosis. (lu.se)

Perhaps one way to come to terms with this conundrum is to consider animal experimentation in more abstract terms, rather than on a case-by-case basis (with many of those "cases" being purely hypothetical). (freakonomics.com)

The E.P.A. has for decades required testing on a variety of animals - including rats, dogs, birds and fish - to gauge their toxicity before the chemicals can be bought, sold or used in the environment. (paperwriting.wiki)
Every year in the United States, millions of animals including monkey's, rats, mice, rabbits, cats, and dogs suffer experimentation to test the biocompatibility of products before they are. (nova.edu)
Heart failure was her area of research, mice and rats her test subjects. (unboundproject.org)
Genes that have been found to be associated with a certain disorder in human patients are knocked out or inserted into the genome of mice, rats or other animals. (eceae.org)

Research groups have now identified a number of predictable, objective and irreversible criteria in several strains of mice that reliably occur during neurodegenerative processes. (nc3rs.org.uk)
Countless articles have been published in the last decades claiming that cancer, diabetes or other diseases have successfully been cured in mice or other animals. (eceae.org)

Animal experimentation may be very harmful to animals and inhumane but it is the only thing right now that is helping to discover new medical advances. (123helpme.com)
Document epidemiological, case study, or experimental research that advances human health without dependence on animal experimentation. (uft.org)
First, animal experimentation has had little, if anything, to do with most medical advances. (uft.org)
Several medical historians have found that most major advances in areas such as heart disease and cancer have developed from human clinical investigation. (uft.org)
On a warm October day in Halifax, Dr. Charu Chandrasekera is attending the inaugural Canadian Animal Law Conference , to speak on a panel entitled, 'Ending Animal Experimentation: New Advances. (unboundproject.org)

2023). Research recommendations for selected IARC-classified agents: impact and lessons learned. (who.int)
2023). Firefighting and cancer: a meta-analysis of cohort studies in the context of cancer hazard identification. (who.int)
2023). IARC-NCI workshop on an epidemiological toolkit to assess biases in human cancer studies for hazard identification: beyond the algorithm. (who.int)

If scientist did not experiment with animals many more people would lose their life (Derbyshire). (123helpme.com)
People are making an effort to save as many animals as possible when trying to experiment. (123helpme.com)
The implications of this sensitivity have radical implications for every experiment done on an animal. (freakonomics.com)
Scientists who might have been rearranging animal subjects for clinical traumatization would have been unwittingly already traumatizing their subjects, thereby screwing up the results and rendering the entire experiment, not to mention the harsh treatment of the rodents, totally pointless. (freakonomics.com)
Especially in the practice of preventive medicine, we are increasingly dependent on the public's understanding of the methods of scientific medicine and of the need to use animal experiment as well as human observation to divine the causes and plan the prevention of disease. (animalresearch.info)
I should therefore confess at once that the last animal experiment I performed was on a frog's leg during my undergraduate training in physiology. (animalresearch.info)
Additionally, improved reporting of thedetailsmaximizes the availability andutility of the information gained fromevery animal experiment, also preventing the unnecessary animal use in thefuture. (ommegaonline.org)
Now, a multidisciplinary research team covering the Check 'animal experiment' translations into Swedish. (web.app)
Look through examples of animal experiment translation in sentences, listen to pronunciation and learn grammar. (web.app)
Approach to Animal Science Experiment. (web.app)
Experiments Each animal biology experiment that Space Biology supports is designed to build our understanding of how the novel environment(s) of spaceflight affect complex multicellular organisms at the molecular, physiological, and systemic levels. (web.app)
In order to conduct animal experiments in Sweden, researchers must first apply for permission to an animal experiment ethical review board, which will run an ethical review of the proposed research study. (lu.se)
The research is to be conducted according to a protocol which has been reviewed and approved by the regional animal experiment ethical review board in Malmö/Lund. (lu.se)
Of the twelve remaining members, one half are researchers, animal experiment technicians or animal experiment staff. (lu.se)

Until such a discovery, animals must continue to play a critical role in helping researchers test potential new drugs and medical treatments for effectiveness and safety, and in identifying any undesired or dangerous side effects, such as infertility, birth defects, liver damage, toxicity, or cancer-causing potential. (stanford.edu)
Stanford Researchers are Obligated to Ensure the Well-Being of All Animals in Their Care. (stanford.edu)
Stanford researchers are obligated to ensure the well-being of animals in their care, in strict adherence to the highest standards, and in accordance with federal and state laws, regulatory guidelines, and humane principles. (stanford.edu)
Researchers requesting use of animal models at Stanford must have their research proposals reviewed by a federally mandated committee that includes two independent community members. (stanford.edu)
Stanford researchers have made many important human and animal life-saving discoveries through their work. (stanford.edu)
Researchers from the University of Pittsburgh and the National Institutes of Health (NIH) Vaccine Research Center have developed an improved way to test potential vaccines against bird flu. (news-medical.net)
Animal researchers and their academic colleagues determine medical school curricula and edit scientific journals. (uft.org)
On Sept. 10, the Environmental Protection Agency said it would move away from requiring the testing of potentially harmful chemicals on animals, a decision that was hailed by animal rights groups but criticized by environmentalists and researchers who said the practice was necessary to rigorously safeguard human health. (paperwriting.wiki)
Interestingly, animal experimentation to address these issues is considered unethical in the European Union, because "tattoos are applied as a matter of choice, and lack medical necessity, similar to cosmetics," the researchers note. (santacruzwire.com)
The turning of the century saw the development and use of animal models for infectious diseases and screening and the evaluation of new antibacterial drugs based upon the work of these three researchers. (ommegaonline.org)
Within the breast cancer research community there is both a need and desire to make this valuable material available for researchers. (whiterose.ac.uk)
To fulfil this unmet need, we have developed a novel initiative called Sharing Experimental Animal Resources: Coordinating Holdings-Breast (SEARCHBreast) which facilitates sharing of archival tissue between researchers on a collaborative basis and, de facto will reduce overall usage of animal models in breast cancer research. (whiterose.ac.uk)
A secure searchable database has been developed where researchers can find, share, or upload materials related to animal models of breast cancer, including genetic and transplant models. (whiterose.ac.uk)
All researchers and animal facilities staff at the MDC are committed to animal welfare, the applicable laws and the ethical standards of the 3R principles. (web.app)

After graduating, she took up a role as a biology teacher at a secondary school, and left after a few years to perform research on tissue culture at the Netherlands Cancer Institute in Amsterdam. (wikipedia.org)
Implementation of systems biology methodologies in nutritional immunology research and discovery. (frontiersin.org)
Interested in gene regulation and RNA biology, my PhD thesis focused on the epigenetic regulation of non-coding RNAs in cancer. (unil.ch)
I obtained my Master's in Molecular and Structural Biology (focusing on cancer research) at the University of Geneva. (unil.ch)
At Feinberg, scientists are pursuing synthetic biology research to address the health challenges and diseases that humans face. (northwestern.edu)
There are seven major areas of medicine and biology, where animals are used, but majority of animal models is used to study the cause, nature and cure of diseases affecting both humans and animals. (ommegaonline.org)
Human biology is very much similar to that of many other animals. (ommegaonline.org)
At present, basic research in many areas of biology and medicine still needs to use animals. (ommegaonline.org)

Animal research is vital to the development of new medicines and therapies. (spiked-online.com)
On the other hand, it is possible that many promising therapies were abandoned because inaccurate animal models yielded discouraging results. (uft.org)
For this purpose, I use different omics layers to identify antigens which can be translated into potential cancer vaccines or cell therapies. (unil.ch)
Additionally, I am working with clinical samples to design of cancer therapies. (unil.ch)

Everyone might agree that animal research provides great benefit but disagree vehemently as to whether it is a morally sound activity. (spiked-online.com)
Animal rights advocates say 22 Mar 2016 Animal experiments result in great benefits for humans and that is perhaps why drug testing on animals is morally acceptable. (web.app)

If animals suffer and experience life in a similar way to us, then animal research is simply wrong, no matter what the outcome, just as non-consensual or detrimental human research would be wrong. (spiked-online.com)
Non-human animals do not appear to suffer from mental diseases as schizophrenia. (uft.org)
I have to live with my condition, I don't expect an animal to suffer or lose its life because of it - that is arrogance beyond belief. (animalaid.org.uk)
Although the shipyard closed in 1974, the Hunters Point community continues to suffer from cancer and other deadly diseases. (nupoliticalreview.org)

Present address: Mater Research Institute, The University of Queensland Translational Research Institute, Queensland 4102, Australia. (biologists.com)
The section will disseminate translational, clinical and mechanistic research related to the modulation of immune responses by foods, dietary ingredients and natural products. (frontiersin.org)
Translational nutritional immunology research. (frontiersin.org)
To promote data reusability, we describe four example use cases where this dataset may be re-analyzed to support basic research, translational investigation, omics data integration, and kinetic modeling. (nature.com)

Some scientists advocate experiments on animals while simultaneously apologising for them. (spiked-online.com)
The point has to do with the fact that, as scientists use animals to further scientific knowledge, they do so without a full, or even half-full, understanding of the animals they're exploiting. (freakonomics.com)
Because the cart of experimentation has been put before the horse of knowledge, scientists routinely end up not only inadvertently harming animals, but unknowingly executing flawed experiments bound to yield inconsistent, and thus ultimately useless, results. (freakonomics.com)
Virtually every time Medical Research Modernization Committee (MRMC) scientists and clinicians have been asked to review animal research projects, they have found significant scientific shortcomings that make the value of the research highly questionable. (uft.org)
MRMC scientists have been particularly critical of animal models of mental illness and addiction. (uft.org)
At Feinberg, scientists across various disciplines are improving the efficiency of breast cancer detection through AI and machine learning, investigating disparities in patient outcomes and identifying new precision medicine strategies through robust clinical, basic science and population-health research. (northwestern.edu)
Genzyme Corporation had a humble beginning as it was founded by a small number of scientists who were devoted to researching diseases that were genetically inherited. (wowessays.com)
Also, research on the long-term health effects of tattooing is in early stages, and scientists note that tattoo inks and pigments are full of sketchy, unregulated, and downright toxic ingredients. (santacruzwire.com)
The experiments carried out on animals are irrelevant (some scientists and doctors are now telling us this) and there are cruelty-free alternatives available. (animalaid.org.uk)
When you think of animal tests, you might think of a mouse or rat running around a maze with curious scientists looking on. (caringconsumer.com)
Scientists at the University of Hong Kong have just released more research findings adding to the growing. (naturalnews.com)
2. 89% of scientists surveyed by the Pew Research Center were in favor of animal testing for scientific research. (web.app)
Unfortunately, the changes were never made and scientists still have the ability to conduct research on one's tissues without consent. (ipl.org)
In order to test cancer treatments, scientists use 2D cultures of cancer cells. (unige.ch)

2020). The key characteristics of carcinogens: relationship to the hallmarks of cancer, relevant biomarkers, and assays to measure them. (who.int)
2020). Epidemiological studies of low-dose ionizing radiation and cancer: rationale and framework for the monograph and overview of eligible studies. (who.int)
2020). Epidemiological studies of low-dose ionizing radiation and cancer: summary bias assessment and meta-analysis. (who.int)

The use of animals in laboratory experimentation is unethical and strongly against animal rights. (123helpme.com)

However, this argument fails to defend basic scientific research and to address concerns about animal welfare. (spiked-online.com)
Moreover, this approach fails to address moral arguments for animal welfare. (spiked-online.com)
It is upon the researcher to ensure that research involving animals will contribute significantly to the health and welfare of either humans or animals. (ommegaonline.org)
NVS), animal welfare officer (e.g. (nc3rs.org.uk)

Throughout history, animal testing has played an important role in leading to new discoveries and human benefit. (123helpme.com)
U.S. federal laws require that non-human animal research occur to show the safety and efficacy of new treatments before any human research will be allowed to be conducted. (stanford.edu)
Not only do we humans benefit from this research and testing, but hundreds of drugs and treatments developed for human use are now routinely used in veterinary clinics as well, helping animals live longer, healthier lives. (stanford.edu)
We cannot justify the instrumental use of animals because we like the outcome any more than we might use a beneficial outcome to justify the instrumental use of human beings. (spiked-online.com)
The instrumental use of animals is only justified if human beings are special. (spiked-online.com)
Arguments in favour of animal research must include an acknowledgement that human beings are special, but science seems quite ambivalent on this point. (spiked-online.com)
Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. (news-medical.net)
This arsenal of technologies does not require any non-human animal experimentation. (neurovigil.com)
As I see it, one point in particular transcends specific examples of animal experimentation to suggest that we should be doing everything possible to eliminate the practice altogether-except perhaps in the most extreme cases of direct human benefit. (freakonomics.com)
A couple of real life examples, both taken from Bernard Rollin 's insightful book Animal Rights and Human Morality , highlight the problem. (freakonomics.com)
The basic problem is that animal models show fundamental anatomical, physiological, and pathological differences from the human disease they are said to mimic. (uft.org)
However, injection of rapidly growing cancer cells into young, healthy animals causes tumors that are biologically different from the major human cancers, which tend to be spontaneous, slow-growing tumors in older people. (uft.org)
In addition to such traditional research methods as clinical trials, epidemiological investigations, biopsy and autopsy, some technologically advanced methods, such as CAT and PET scans, cell and tissue cultures, computer models, and computerized post-market surveillance of drugs, permit safe, direct study of human disease. (uft.org)
I focus my work on the identification of clinically relevant cancer specific Human Leukocyte Antigen (HLA) ligands that will guide the development of personalized cancer immunotherapy. (unil.ch)
We can protect human health and the environment by using cutting-edge, ethically sound science in our decision-making that efficiently and cost-effectively evaluates potential effects without animal testing," Mr. Wheeler said in a memo announcing the changes. (paperwriting.wiki)
Medical research charities claim that they conduct animal research for the benefit of patients, but animal 'models' of human disease not only cause immense suffering, they are also unreliable and the results gained can be dangerously misleading. (animalaid.org.uk)
Non-animal research methods allow us to obtain data that is more accurate and relevant to human health, and therefore more likely to lead to effective treatments. (animalaid.org.uk)
Over the last 5 years it has been discovered - through human patients - that this drug has many more undesirable side effects than were discovered by animal testing, and many people (including myself) have been taken off them. (animalaid.org.uk)
I am a vegan and have been an animal and human rights campaigner for 30 years. (animalaid.org.uk)
Most laboratory animals have the same set of organs - heart, lungs, liver, and so on which work in the same way as they do in human. (ommegaonline.org)
Besides the spread of radioactive material, there were nuclear weapons tests, animal experimentation, and possibly human experimentation that also took place at the shipyard. (nupoliticalreview.org)
A human mind can commit errors especially that he can't be aware of all the side effects of the ingredients, this is why machines are very helpful and important in a research. (ipl.org)
I recently finished reading The Immortal Life of Henrietta Lack, a biography about Henrietta Lacks and how human tissue was taken without consent then used for medical research. (ipl.org)
Today, she notes, drugs tested to be safe and/or effective in animal models have a 95 percent failure rate in human trials. (unboundproject.org)
Brain organoids derived from human iPSCs can develop brain tumours (2), e.g. by adding human brain cancer cells (3). (eceae.org)
There is no doubt that these models poorly reflect complex human diseases such as Alzheimer's disease, diabetes or cancer. (eceae.org)
Many so-called "animal models" try to mimic a certain aspect or symptom of a human disease by artificially harming animals. (eceae.org)
Many animal models of human diseases including Alzheimer's disease or cancer are generated by genetic engineering. (eceae.org)
Instead of effectively improving human health and driving the understanding and therapy of human diseases this research strategy provides huge amounts of false positive and false negative results. (eceae.org)
In addition, the Eastmond laboratory has an active research program in which molecular cytogenetic techniques are used to detect chromosomal alterations occurring in chemically exposed human populations. (cdc.gov)

NeuroVigil is a global neurotechnology pioneer which develops proprietary non-invasive brain monitors and advanced machine learning algorithms to detect a constellation of biomarkers of pathologies in asymptomatic individuals, such as people with neurodegeneration, adverse drug side effects or brain cancer, and to ascertain intent including, at the request of the late Dr. Stephen Hawking, in individuals who cannot otherwise communicate. (neurovigil.com)
Notes on chimpanzee behaviour while they are kept for invasive research. (unboundproject.org)
Transcriptomic profiling of T-cell populations in non-muscle invasive and muscle invasive bladder cancer. (lu.se)

The best hopes to cure malaria, Parkinson's and Alzheimer's diseases, epilepsy, obesity, infertility and a variety of birth defects all rely on current animal experiments. (spiked-online.com)
Other animal-based experiments, however, appear to have genuine utilitarian value, contributing useful information to our knowledge of Parkinson's, Alzheimer's, and several cancers. (freakonomics.com)
This knowledge can lead to better diagnosis and treatment of many diseases, such as cancer, diabetes, Parkinson's, stroke and lung diseases. (lu.se)

I have had epilepsy for over 40 years, and it has not always been under good control, which means I have had many tablet changes - undoubtedly tested on animals. (animalaid.org.uk)

It is our moral duty to ascertain that animal experimentation should cause as little suffering to animals, as possible and should only be performed where necessary. (ommegaonline.org)

Doing tests on animals can help find ways to cure diseases, but testing on them is wrong. (123helpme.com)
Although we want to find cures for diseases to help many people, testing on animals not only brutally hurts them but it also denies the animals the rights they have. (123helpme.com)
If cannabis use affects cellular processes then users may be at increased risk of developing various types of cancer, and if it affects the immune system then cannabis users may be at increased risk of contracting infectious diseases and developing cancer. (druglibrary.org)
Such countries intended to encourage developments in drug research, diagnostics, and vaccines that would help improve the treatment options for such rare diseases (Pryde & Groft, 2014). (wowessays.com)
Prior to the June 2011 launch of our Victims of Charity campaign, we invited people who are suffering from diseases such as cancer and heart disease to get in touch with us, and declare their opposition to the animal experiments that are conducted in their name. (animalaid.org.uk)
At present, animals in research are essential not only in areas of neurological, infectious, digestive, genetic and chronic diseases, but also play a crucial role in the development of antibiotics, vaccines as well as in proper understanding of various diagnostics and prognostic tests. (ommegaonline.org)
While humane endpoints should be considered for all experiments involving animals, they are essential in studies where potential severe suffering or death may be involved (e.g. acute toxicology, animal models of infection, cancer and neurodegenerative/inflammatory diseases). (nc3rs.org.uk)
Expertise / Discipline: study of occupational and environmental exposures to chemicals and radiation as risk factors for cancer, autoimmune diseases, and intermediate biologic effects. (cdc.gov)

At a time when animal experiments are widely criticised, it is no surprise that their defenders emphasise these experiments' clinical benefit. (spiked-online.com)
In the public sphere, and increasingly in the academic sphere, there is a demand that the outcome of any research project involving animals be self-consciously directed towards a clinical therapy, rather than a process of scientific enquiry. (spiked-online.com)
Although hormone therapy with an anti-estrogen agent is an optional therapy for recurrent epithelial ovarian cancers, both basic and clinical researches are insufficient. (biomedcentral.com)
The autopsy rate in the United States has been falling steadily, much to the regret of clinical investigators, who recognize the value of this traditional research tool. (uft.org)
The more I learned about cancer, the better I understood that its therapy should rely on a personalized and exhaustive molecular and cellular characterization of tumors and that immunotherapy represents the most promising clinical approach. (unil.ch)
The remaining percentage of animal tests and clinical trials are split relatively evenly among the above animal species. (caringconsumer.com)
Clinical trials are a branch from the research that helps answering the question about safety and benefits of a new intervention. (ipl.org)

Animals are biologically very similar to humans. (stanford.edu)
Biologically active peptides have attracted increasing attention in research on the development of new drugs. (bvsalud.org)

Bemcentinib is an AXL inhibitor, a novel type of cancer therapeutic agent. (oslocancercluster.no)
The therapeutic effect of AIs has been shown to be superior to that of tamoxifen as adjuvant therapy for breast cancer [ 14 ]. (biomedcentral.com)
On the other hand, their therapeutic use for other purposes would be limited in patients with impaired immune systems, a restriction which would potentially preclude their use as anti-emetic agents in cancer chemotherapy, or as appetite stimulants and mood enhancers in patients with AIDS. (druglibrary.org)
Animal models are increasingly used to understand disease mechanisms and to screen promising therapeutic approaches. (sbir.gov)

Animal models have contributed to our understanding of breast cancer, with publication of results in high-impact journals almost invariably requiring extensive in vivo experimentation. (whiterose.ac.uk)

Thus the purpose of basic animal research is to understand the animal world, and can include investigations of animal behaviour as well as animal physiology - for example, the study of migratory behaviour in birds or the study of barrel structures in the rat cerebral cortex. (spiked-online.com)
Humans have been using animals as models of their anatomy and physiology since the dawn of medicine. (ommegaonline.org)

Many people have questions about animal testing ethics and the animal testing debate. (stanford.edu)

I'm sure that if one of my children were afflicted with a life threatening disease and experimentation on monkeys had a plausible chance of finding a cure, I'd reluctantly support that research. (freakonomics.com)

We here examine the efficacy of an aromatase inhibitor (AI) for peritonitis carcinomatosa, the late stage of ovarian cancer. (biomedcentral.com)

My research interests include the discovery of personalized neo-antigens and non-canonical antigens in patient tumor samples, exploring their possible different sources, including the possible translation of some non-coding RNAs. (unil.ch)
My thesis focused on studying the anti-tumor immune responses induced by concomitant chemoradiation in non-small cell lung cancer, head and neck cancer patients and in mouse tumor models. (unil.ch)

It will also suggest a variety of non-animal methodologies that could be used as alternatives to animal research. (uft.org)
She joined the American non-profit, The Physicians Committee for Responsible Medicine , which promotes plant-based eating, as well as preventive medicine and alternatives to animal research. (unboundproject.org)

Submenu for How does research happen? (lu.se)

Dr. Charu Chandrasekera - Executive Director of the Canadian Centre for Alternatives to Animal Methods. (unboundproject.org)
Though her story lands her today as the Executive Director of the Canadian Centre for Alternatives to Animal Methods at the University of Windsor in Ontario, Canada, it surprisingly didn't start with concern for animals. (unboundproject.org)

With a shorter life cycle than humans, animal models can be studied throughout their whole life span and across several generations, a critical element in understanding how a disease processes and how it interacts with a whole, living biological system. (stanford.edu)
The development of artificial arteries, understanding the ageing process and reversing spinal-cord injury are all being investigated using animal models. (spiked-online.com)
Frontiers is well aware of the potential impact of published research both on future research and on society and, hence, does not support superficial review, light review or no-review publishing models. (frontiersin.org)
Since, new animal models are continually being characterized, identifying and selecting the most appropriate animal model is the single most essential element in animal-based research. (ommegaonline.org)
Additionally, SEARCHBreast is committed to promoting the use of humanised breast tissue models as replacement alternatives to animals. (whiterose.ac.uk)
EpiZode: Noninvasive Seizure Screening in Preclinical Models of Epilepsy There is an urgent need for research into treatment options for epilepsy and other seizure disorders. (sbir.gov)
We had a number of different animal models of this," she says, "and when I came back to the lab I talked to my professor I was working for, and I said 'Do you think these receptors were activated in my dad during his heart attack? (unboundproject.org)
In the recent past, scientific experts from academia and industry have increasingly criticized animal-based disease models. (eceae.org)

In this case, the technology enhances the effect of other cancer vaccines. (oslocancercluster.no)
This novel strategy can potentiate the recognition of cancer-associated/-specific neoantigens from source-limited biopsies and the development of individualized cancer vaccines. (unil.ch)

Estrogen causes proliferation of ovarian cancer cells. (biomedcentral.com)
Estrogen receptor (ER)α was assayed in four ovarian cancer cell lines by the RT-PCR method. (biomedcentral.com)
Ovarian cancer is still the most lethal of all gynecologic cancers. (biomedcentral.com)
The American Cancer Society estimated that about 22,240 new cases of ovarian cancer will be diagnosed and 14,030 women will die of ovarian cancer in the United States in 2013 [ 1 ]. (biomedcentral.com)
There are various methods for treating of recurrent ovarian cancer and chemotherapeutic regimen is chosen based on platinum susceptibility but there is no established second-line therapy. (biomedcentral.com)
In the National Comprehensive Cancer Network (NCCN) guidelines (version 3, 2012), hormone therapy is classified under "other drugs that are potentially effective" as "approved treatment for recurrent forms" of epithelial ovarian cancer. (biomedcentral.com)

The technology helps to transport cancer medicine more effectively to the targeted cancer cells. (oslocancercluster.no)
It aims to improve the release of big molecules and chemotherapy drugs to the targeted cancer cells. (oslocancercluster.no)
6.1 Mutagenicity and carcinogenicity A major reason for research into the effects of cannabinoids on cellular processes is to discover whether cannabinoids are mutagenic, i.e. whether they may produce mutations in the genetic material in the somatic and germ cells of users. (druglibrary.org)
If cannabinoid exposure affects the genetic material of a user's somatic or bodily cells (such as those of the lung, for example) then chronic cannabis use may cause cancer. (druglibrary.org)
There is experimental evidence from in vitro studies of animal cells that some cannabinoids, including THC, can produce a variety of changes in cellular processes in vitro (i.e. in the test tube). (druglibrary.org)
It also allowed me to acquire immunological techniques, such as animal experimentation, mutiparametric flow cytometry, ELIspot, ELISA and lymphoid cells culture. (unil.ch)
Once this step has been completed, which takes 24 hours, we can test the various possible treatments for this cancer on our reproduction of the tumour and study which one will be most suitable for the patient, taking into account the effects on the tumour cells, but also on the immune system", explains Patrycja Nowak-Sliwinska. (unige.ch)
Previously, our research team had found that two molecules, or more specifically, co-transcriptional regulators, known as YAP and TAZ, are involved in the damage of the lung epithelial cells. (lu.se)

According to an article by PETA, "experiments on animals are cruel, expensive and generally inapplicable to humans" (PETA 1). (123helpme.com)
for he was a man of remarkable courage in the defence of the often unpopular cause of a disciplined freedom to pursue knowledge through experiments on animals. (animalresearch.info)

They are also obligated to continuously update their animal-care practices based on the newest information and findings in the fields of laboratory animal care and husbandry. (stanford.edu)
When the use of laboratory animal is obligatory, the most appropriate specie, breed, and strain with the closest homology to humans must be chosen. (ommegaonline.org)
Veterinary assistants and laboratory animal caretakers did not have higher likelihood of suicide. (cdc.gov)

This shows how not only many laboratories and companies that use animals in their experiments are wasting money and time, but also wasting countless lives of animals. (123helpme.com)
It is my belief and philosophy that animals are not utilities or property, and just as I do not want my stomach to be a graveyard for animals, I do not want my health to be dependent on the torture of sentient creatures in vivisection laboratories. (animalaid.org.uk)
As such, many laboratories hold large collections of surplus animal material, with only a fraction being used in publications relating to the original projects. (whiterose.ac.uk)
That means for every minute that ticks by, seven animals die in British laboratories. (web.app)

Breast Cancer Research and Treatment, 156 (3). (whiterose.ac.uk)
That same weekend, coincidentally, the Canadian Cancer Society's CIBC Run For The Cure is also taking place, to raise funds for breast cancer research. (unboundproject.org)

Cancer Res (2017) 77 (8): 2052-2063. (aacrjournals.org)

Animals are used to test new medical treatments to see if they will be effective on humans. (123helpme.com)
Antiviral immune responses present a major hurdle to the efficacious use of oncolytic adenoviruses as cancer treatments. (aacrjournals.org)
Previously, following the applied focus of my Degree in Pharmaceutical Sciences, I decided to deepen my knowledge of basic research, aiming to combine further both areas to develop innovative anticancer treatments. (unil.ch)
The majority of experimental animal treatments with oestrogens, which have resulted in carcinogenesis, have been at very high dose levels. (inchem.org)
NaturalNews) After a diagnosis of breast cancer, most women want to know where they fit into the statistics being quoted to them as reasons for submitting to the traditional toxic treatments being advocated by their oncologists. (naturalnews.com)

An article in the New England Journal of Medicine justified animal use in cancer research on the ground that "cancer kills humans and animals alike. (uft.org)

Based on the research findings, it will be important to ensure suicide prevention activities are aimed at veterinary technicians as well as veterinarians. (cdc.gov)

Together, our results support that a high intake of dietary LA could cause adverse effects on colon cancer through the CYP/EpOME eicosanoid pathway. (umass.edu)
Hence we come to what may very well be the inherent problem of animal experimentation: because we can never predict how an inarticulate animal capable of experiencing fear or pain or distress will react to the almost incalculable and endlessly subtle stimuli of any scientific environment, we can never fully trust the experimental results. (freakonomics.com)
Besides, it has been extensively proven that results from animal experimentation are not transferable to humans. (animalaid.org.uk)
results from animal experimentations are applied to humans. (ommegaonline.org)
It is largely stressed that the well-being of participants should be the main priority of the study, above research goals and quick results. (ipl.org)
These results can be read in the journal Cancers . (unige.ch)
Research combining mastery in distinct fields or disciplines that apply and exchange tools, concepts, ideas, data methods, or results around a common project. (bvsalud.org)

Animal experimentation is used in order to test products and to discover new medical research. (123helpme.com)
The development and enhancement of medical research has been based on the testing of animals. (123helpme.com)
We take our responsibility for the ethical treatment of animals in medical research very seriously. (stanford.edu)
This unit will aquatint students with some of the Medical Research Modernization Committee's concerns about the scientific value of animal research. (uft.org)
The last #IMIMseminarsathome presented the two first projects from the Hospital del Mar Medical Research Institute (IMIM) that deal with Covid19. (prbb.org)
It's medical research that seeks to appreciate the everyday reality of living with multiple forms of illness and harm. (nyu.edu)
The first written with Stefanos Geroulanos, who teaches in the history department at NYU, on concepts of homeostasis and holism that emerged out of medical research during the First World War, entitled The Brittleness of the Body. (nyu.edu)
A good example would be the brain, since there is still a lot we do not know about how it works and if we are to find answers to these important questions, fundamental research must continue.The information acquired by fundamental research often provides new insights into more applied medical research that ultimately leads to the developmentof new medicines. (ommegaonline.org)
As Humane Society International highlights, for example, over 12 million animals are experimented on within Europe every year, particularly for medical research. (caringconsumer.com)
Most of the medical research at Lund University is conducted in test tubes or using cell culture techniques. (lu.se)
We acknowledge support from the Joint European Medical Research Board (JEMRB), which pro- vided both the finance for this work and the data from the inhalation experiments. (cdc.gov)
DOCUMENTATION FILE ONLY MESSAGE FROM SURGEON GENERAL SURGEON GENERAL'S REPORT TO THE AMERICAN PUBLIC ON HIV INFECTION AND AIDS A Message from the Surgeon General It began, like so many epidemics, with a few isolated cases, a whisper that caught the ear of only a few in medical research. (cdc.gov)

With the increasing pressure to reduce animal experimentation, a model to predict the retained burden would have real utility. (cdc.gov)

A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications. (mdpi.com)
Investigations are performed using a variety of chemical, biochemical and molecular approaches with isolated enzyme, cell culture and animal model systems. (cdc.gov)

Secrecy encourages infiltration and exposure by animal rights groups, while stretching the medical claim opens up a gap between the reality and rhetoric of science. (spiked-online.com)
This platform opens up many possibilities for testing drug combinations, taking into account the different types of cancer, their mutations and the immune reactions specific to each person treated", concludes Patrycja Nowak-Sliwinska. (unige.ch)

The E.P.A. recently said it would move away from requiring the testing of potentially harmful chemicals on animals. (paperwriting.wiki)
We want proper animal testing because we don't want harmful chemicals to end up in our food, air and water. (paperwriting.wiki)
Do you support the decision by the E.P.A. to move away from requiring the testing of potentially harmful chemicals on animals? (paperwriting.wiki)
Or do you think animal testing is still necessary to regulate harmful substances that can have adverse effects on humans? (paperwriting.wiki)
He gave three reasons: "These manufacturers or promoters of these harmful things have a secret agenda which only further research can reveal. (currenthealthscenario.com)

All who care about the prevention of disease, whether in animals or humans, must certainly feel themselves in his debt. (animalresearch.info)
Invited perspective: good measure-assessing the impact of cancer hazard identification on policies for cancer prevention. (who.int)
World Cancer Report: Cancer Research for Cancer Prevention. (who.int)

video image Ati bipolar disorder video case study essays about dogs as pet animal essay on My experiments with truth essay in english: descriptive case study design. (web.app)
Titles for essays on standardized testing outline ap essay lang Synthesis outline animal experiments harrah's case study customer relationship management. (web.app)
Master dissertation research essay about moonlit, an essay on interpersonal Research papers over animal abuse teacher student interaction a case study Pioneers in experimental sketch comedy since the dawn of the 21st century! (web.app)
Previous Ministry experiments have provided answers to mankind's eternal Ieee research paper on pattern recognition write essay on narendra modi in good ways to start narrative essay animal hunting persuasive essay, essay about Animal experimentation. (web.app)

There are many negatives to animal experimentation such as the cost and the treatment of the animals. (123helpme.com)
Our member PCI Biotech, a Norwegian biopharmaceutical company, has secured a US patent for one of their cancer treatment technologies. (oslocancercluster.no)
The combination treatment has shown to be effective when enhancing the immune responses in cancer patients to fight off cancer. (oslocancercluster.no)
Cancer-related fatigue (CRF) is a debilitating yet all-too-common condition, which can severely affect quality of life for patients undergoing treatment. (news-medical.net)
Letrozole is an oral non-steroidal AI and used for the treatment of local or metastatic breast cancer that is ER positive. (biomedcentral.com)
The billions of dollars currently spent on animal experimentation should be redirected to more productive research methods, preventative health programs, and treatment facilities. (uft.org)
When they are used for the treatment of disseminated cancer such as that of the breast, prostate and endometrium, their effect on tumour growth and the severity of side-effects are the major considerations. (inchem.org)
When relevant criteria are identified, actions such as humane killing , modification of the experimental design, analgesic administration and/or treatment of the animals can then be carried out to prevent or alleviate pain and/or distress. (nc3rs.org.uk)
Nowadays researches won't be conducted unless the participants are fully aware of the potential risks that they might encounter and they should be informed of the kind of treatment they will receive. (ipl.org)
Henrietta Lacks, was a colored woman, she was the daughter of a tobacco farmer, she came from a very poor, with very little education, she died from uremic poisoning, due to the treatment for cervical cancer October of 1951 at age 31. (ipl.org)
So how do we know which treatment will work best for the patient and eradicate the cancer? (unige.ch)
This technique, which is relatively inexpensive and fast, would make it possible to propose a personalised treatment for each patient, while offering an effective alternative to several animal experimentations. (unige.ch)

We at Stanford are dedicated to refining, reducing, and replacing animals in research whenever possible, and to using alternative methods (cell and tissue cultures, computer simulations, etc.) instead of or before animal studies are ever conducted. (stanford.edu)
The study is directed towards patients with mesothelioma, a type of cancer that develops in the thin layer of tissue that covers many of the internal organs, for example the lining of the lungs or chest wall. (oslocancercluster.no)
Analyzing small-scale tissue and cell samples can help us discover unique immunogenic cancer antigens. (unil.ch)

According to the American Anti-Vivisection Society , guinea pigs are the most common research animals, representing 22% of all animal experiments. (caringconsumer.com)

Animal Experimentation Jeremy Bentham a philosopher and a utilitarian humanitarian once said, "The question is not, "Can they reason? (123helpme.com)

Administration of the natural oestrogens, oestradiol-17 b and oestrone, increases the incidence of tumours in a number of organs in a variety of animal species. (inchem.org)

This reliability on technology will help improving the infrastructure since it requires very developed and modern equipment in order to perform the researches with high precision. (ipl.org)

Adrian Smith, Eddie Clutton, Elliot Lilley, Kristine Hansen & Trond Normative Dilemmas in Sweden's Ethical Review Policy for Animal Experiments. (web.app)

In 1865, Claude Bernard, a French physiologist published a book, An Introduction to the Study of Experimental Medicine, intended to provide guidance to physicians in experimental research[5]. (ommegaonline.org)

The company successfully went to market in 2009, garnered research contracts with elite pharmaceutical companies, and spearheads a growing international preventive health conglomerate of leading innovators and entrepreneurs. (neurovigil.com)

The success of these methods counters claims that animal experimentation is necessary. (uft.org)
I don't believe it is necessary as there are many other more reliable methods of research. (animalaid.org.uk)
Animal experiments are only permitted where no alternative methods are available. (lu.se)

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