Congophilic angiopathyHereditary cerebral amyloid anAmyloid plaquesSporadicCerebral CortexAlzheimer'sDisease of the blood vesselsCognitive impairmentIntracranial hemorrhageBiomarkersStrokeInflammationMicroangiopathyIntracerebralDiseasesComplicationBrainPeripheralMagnetic ResonanPlaquesDiagnosisAtherosclerosisImagingBloodPatientsCommonTotal
Congophilic angiopathy1
- Cerebral amyloid angiopathy (CAA), also known as congophilic angiopathy, is a recognized cause of lobar intracerebral haemorrhage in patients above the age of 50 years. (touchneurology.com)
Hereditary cerebral amyloid an11
- Hereditary cerebral amyloid angiopathy is a condition characterized by an abnormal buildup of protein clumps called amyloid deposits in the blood vessels in the brain, causing vascular disease (angiopathy). (medlineplus.gov)
- People with hereditary cerebral amyloid angiopathy often have progressive loss of intellectual function (dementia), stroke, and other neurological problems starting in mid-adulthood. (medlineplus.gov)
- There are many different types of hereditary cerebral amyloid angiopathy. (medlineplus.gov)
- The various types of hereditary cerebral amyloid angiopathy are named after the regions where they were first diagnosed. (medlineplus.gov)
- The Dutch type of hereditary cerebral amyloid angiopathy is the most common form. (medlineplus.gov)
- People with the Flemish and Italian types of hereditary cerebral amyloid angiopathy are prone to recurrent strokes and dementia. (medlineplus.gov)
- The first sign of the Icelandic type of hereditary cerebral amyloid angiopathy is typically a stroke followed by dementia. (medlineplus.gov)
- Strokes are rare in people with the Arctic type of hereditary cerebral amyloid angiopathy, in which the first sign is usually memory loss that then progresses to severe dementia. (medlineplus.gov)
- Two types of hereditary cerebral amyloid angiopathy, known as familial British dementia and familial Danish dementia, are characterized by dementia and movement problems. (medlineplus.gov)
- The prevalence of hereditary cerebral amyloid angiopathy is unknown. (medlineplus.gov)
- Variants (also called mutations) in the APP gene are the most common cause of hereditary cerebral amyloid angiopathy. (medlineplus.gov)
Amyloid plaques1
- Micrograph of a section of the cerebral cortex from a person with Alzheimer's disease , immunostained with an antibody to amyloid beta (brown), a protein fragment that accumulates in amyloid plaques and cerebral amyloid angiopathy . (wikipedia.org)
Sporadic1
- Scholars@Duke publication: Cystatin C mutation in an elderly man with sporadic amyloid angiopathy and intracerebral hemorrhage. (duke.edu)
Cerebral Cortex2
- Cerebral amyloid angiopathy (CAA) refers to the deposition of β-amyloid in the media and adventitia of small and mid-sized arteries (and, less frequently, veins) of the cerebral cortex and the leptomeninges. (medscape.com)
- The cerebral cortex in cerebral amyloid angiopathy. (rush.edu)
Alzheimer's5
- BACKGROUND: The majority of patients with Alzheimer's disease (AD) exhibit amyloid-β (Aβ) deposits at the brain vasculature, a process referred to as cerebral amyloid angiopathy (CAA). (amsterdamumc.org)
- Cerebral amyloid angiopathy (CAA) is an age-related condition and a major cause of intracerebral hemorrhage and cognitive decline that shows close links with Alzheimer's disease (AD). (biomedcentral.com)
- Amyloid β-peptide (Aβ) deposition in cerebral vessels contributes to cerebral amyloid angiopathy (CAA) in Alzheimer's disease (AD). (nature.com)
- Objective: To investigate the association between the extent of cerebral amyloid angiopathy (CAA) and Apolipoprotein E (Apo E) e4 allele in Alzheimer's disease (AD). (confex.com)
- Cerebral amyloid angiopathy (CAA) is a devastating condition common in patients with Alzheimer's disease but also observed in the general population . (bvsalud.org)
Disease of the blood vessels1
- Angiopathy is the generic term for a disease of the blood vessels (arteries, veins, and capillaries). (wikipedia.org)
Cognitive impairment1
- Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress. (bvsalud.org)
Intracranial hemorrhage3
- The Boston Cerebral Amyloid Angiopathy Group has elaborated guidelines for the diagnosis of cerebral amyloid angiopathy (CAA) associated with intracranial hemorrhage (ICH). (medscape.com)
- Research conducted by Sheharyar Jamali, MD, and Michelle Lin, MD, MPH, showed that aspirin lowers the risk of ischemic stroke without increasing the risk of intracranial hemorrhage in patients with cerebral amyloid angiopathy. (neurologylive.com)
- Cerebral amyloid angiopathy is a disorder that affects the small blood vessels in the brain and causes them to be very leaky, thus increasing the risk of intracranial hemorrhage. (neurologylive.com)
Biomarkers1
- Cerebral Amyloid Angiopathy-Related Inflammation Biomarkers: Where are we Now? (iospress.com)
Stroke3
- Patient A.D., a physical fit senior woman, suffered a bleeding stroke, attributed to Cerebral Amyloid Angiopathy, in her left occipital lobe. (amyloidangiopathy.com)
- How do we prevent the ischemic stroke burden in these patients with cerebral amyloid angiopathy? (neurologylive.com)
- The best study we can do is a randomized controlled trial, where we randomize patients with cerebral amyloid angiopathy into an aspirin versus no aspirin arm and see whether there's an increased risk of ischemic or hemorrhagic stroke in that scenario. (neurologylive.com)
Inflammation3
- This case highlights unique imaging findings of cerebral amyloid angiopathy-related inflammation (CAA-ri). (touchneurology.com)
- We report a biomarker and genetic evaluation of four patients with cerebral amyloid angiopathy-related inflammation (CAA-ri) treated with corticosteroids. (iospress.com)
- Cerebral amyloid angiopathy- related inflammation (CAA-ri) is an aggressive disease subtype of CAA with characteristic clinical and radiological findings. (iospress.com)
Microangiopathy1
- There are two types of angiopathy: macroangiopathy and microangiopathy. (wikipedia.org)
Intracerebral3
- The disease was clinically characterized by multiple and complex intracerebral hemorrhages, so it was also known as cerebral amyloid angiopathy hemorrhage (CAAH) [ 2 , 3 ]. (ijpsonline.com)
- OBJECTIVE: To gain insight into different cerebral amyloid angiopathy (CAA) phenotypes and mechanisms, we investigated cortical superficial siderosis (CSS), a new imaging marker of the disease, and its relation with APOE genotype in patients with pathologically proven CAA, who presented with and without intracerebral hemorrhage (ICH). (mcmaster.ca)
- BACKGROUND: Cerebral amyloid angiopathy (CAA) with intracerebral hemorrhage (ICH) occurs both sporadically and as a result of mutations in either cystatin C or the amyloid precursor protein. (duke.edu)
Diseases2
- Cerebral amyloid angiopathy (CAA) was a group of diseases characterized by the deposition of the insoluble fibrin (glycoprotein) in brain tissue. (ijpsonline.com)
- Jamali, a neurologist from Mayo Clinic, noted that despite the insignificance, these results open the door for future research opportunities to evaluate the use of antiplatelets among patients with cerebral amyloid angiopathy and other similar diseases. (neurologylive.com)
Complication1
- The best known and most prevalent angiopathy is diabetic angiopathy, a common complication of chronic diabetes. (wikipedia.org)
Brain2
- Cerebral amyloid angiopathy affects the small-to-medium-sized cerebral arteries most commonly resulting in asymptomatic microhaemorrhages and symptomatic lobar brain haemorrhages. (bmj.com)
- Down syndrome, Alzheimer disease, and cerebral amyloid angiopathy: the complex triangle of brain amyloidosis. (bvsalud.org)
Peripheral1
- In individuals with diabetes, the body's ability to produce or utilize insulin, a hormone that helps to regulate blood sugar levels, suffers diabetic peripheral angiopathy without gangrene. (microqnix.com)
Magnetic Resonan3
- To investigate the diagnostic value of the magnetic susceptibility-weighted imaging and routine magnetic resonance imaging in cerebral amyloid angiopathy hemorrhage. (ijpsonline.com)
- Magnetic susceptibility-weighted imaging has obvious advantages in detecting the micro cerebral hemorrhage, and it can show the characteristics of the cerebral amyloid angiopathy multiple hemorrhages, and its diagnostic value was better than that of routine routine magnetic resonance imaging. (ijpsonline.com)
- Magnetic resonance imaging (MRI) showed diffuse vasogenic oedema in both cerebral hemispheres, intervening zones of gyral oedema, a tiny acute petechial haemorrhage and leptomeningeal enhancement with diffuse signal dropout supportive of amyloid angiopathy ( Figure 1A ). (touchneurology.com)
Plaques1
- Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles. (alzforum.org)
Diagnosis1
- The consistency of the two detection methods in the diagnosis of cerebral amyloid angiopathy hemorrhage and the difference in image quality were analyzed. (ijpsonline.com)
Atherosclerosis1
- One of the most severe complications of atherosclerosis is arterial occlusive disease (AOD) and with diabetic angiopathy (DA), is a common chronic problem in clinical practice worldwide. (ahyperbaric.com)
Imaging1
- Physiologic, hematologic, and imaging data show not only the presence of a hypercoagulable phenotype in severe COVID-19 pneumonia but also markedly impaired pulmonary perfusion likely caused by pulmonary angiopathy and thrombosis. (nih.gov)
Blood1
- Figure 8: SRF and MYOCD control blood flow and cerebral amyloid angiopathy (CAA). (nature.com)
Patients7
- A total of 64 patients with suspected cerebral amyloid angiopathy hemorrhage diagnosed in our hospital from January 2018 to January 2019 were included in the study. (ijpsonline.com)
- The findings add to the body of evidence for use of antiplatelets in patients with cerebral amyloid angiopathy. (neurologylive.com)
- Patients with cerebral amyloid angiopathy tend to be older. (neurologylive.com)
- I think an interesting topic to study in the future would be to look at patients with cerebral amyloid angiopathy who also have another disorder called atrial fibrillation. (neurologylive.com)
- We conducted a clinical prospective study and included a total of 80 patients, divided into two groups: 40 patients with the arterial occlusive disease and lower-extremity wounds, with sub-group (n=20) treated with HBO therapy on the top of the standard therapy and 40 patients with diabetic angiopathy and diabetic lower-extremity wounds, with sub-group (n=20) treated with HBO therapy on top of the standard therapy. (ahyperbaric.com)
- A search was carried out through Internet resources for the period from1991 to December 2020 publications containing the clinical results of the use of color light therapy in the treatment of patients with diabetic neuro and angiopathies and ulcerative lesions of the lower extremities in peerreviewed domestic and foreign scientific journals. (bioresonancetoba.ir)
- Streptococcus species [ 3 ], although an in- tion as determined by the Wagner classifi- creasing number of patients have been en- cation. (who.int)
Common1
- Hypertension and cerebral amyloid angiopathy (CAA) are the most common causes of primary ICH, but the mechanism of hemorrhage in both conditions is unclear. (nature.com)
Total1
- T2D pancreata had greater ADM, angiopathy, and total T lymphocytes, but no difference in adipocyte number, compared to ND organs. (figshare.com)