• Here is a list of the ones found so far: IQGAP1 (IQ-domain GTP-ase Activating Protein): an effector of RhoC to enhance expression of cyclin E and cyclin D1. (wikipedia.org)
  • Besides the effect on cell migration, exogenous Tβ 4 was found to have multifunctional activities such as angiogenesis, anti-apoptosis, anti-oxidative stress and anti-inflammation ( 8 - 11 ), which emphasize its therapeutic potential in the repair of damaged tissues or wound healing. (spandidos-publications.com)
  • Tyrosine phosphorylation of the scaffold protein IQGAP1 in the MET pathway alters function. (nih.gov)
  • Ubiquitination of the scaffold protein IQGAP1 diminishes its interaction with and activation of the Rho GTPase CDC42. (nih.gov)
  • We analized the expression of the scaffold proteins IQGAP1, FKBP51 and AmotL2 and the Na,K-ATPase α and β subunits in colorectal cancer and liver metastases after the administration of oxaliplatin-based chemotherapy. (ull.es)
  • 4. The c-Cbl ubiquitin ligase regulates nuclear β-catenin and angiogenesis by its tyrosine phosphorylation mediated through the Wnt signaling pathway. (nih.gov)
  • 17. IQGAP1-dependent signaling pathway regulates endothelial cell proliferation and angiogenesis. (nih.gov)
  • Endothelial IQGAP1 regulates leukocyte transmigration by directing the LRBC to the site of diapedesis. (nih.gov)
  • IQGAP1 causes choroidal neovascularization by sustaining VEGFR2-mediated Rac1 activation. (nih.gov)
  • Arora PD, Nakajima K, Nanda A, Plaha A, Wilde A, Sacks DB, McCulloch CA. Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodeling. (nih.gov)
  • Zhang M, Li Z, Jang H, Hedman AC, Sacks DB , Nussinov R. Ca2+-dependent switch of calmodulin interaction mode with tandem IQ motifs in the scaffolding protein IQGAP1. (nih.gov)
  • 6. A role for protein ubiquitination in VEGFR-2 signalling and angiogenesis. (nih.gov)
  • Absence of IQGAP1 protein leads to insulin resistance. (nih.gov)
  • Here is a list of the ones found so far: IQGAP1 (IQ-domain GTP-ase Activating Protein): an effector of RhoC to enhance expression of cyclin E and cyclin D1. (wikipedia.org)
  • Various cell types release these vesicles to contribute to many cellular functions, including intercellular communication, cell proliferation, differentiation, angiogenesis, response to stress, and immune system signaling. (biomedcentral.com)
  • The identified candidate genes have critical functions in heart development, such as angiogenesis, mechanotransduction, regulation of heart size, chromatin remodeling, or ciliogenesis. (nature.com)
  • 2. A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis. (nih.gov)
  • 5. c-Cbl inhibits angiogenesis and tumor growth by suppressing activation of PLCγ1. (nih.gov)
  • IQGAP1 binds AMPK and is required for maximum AMPK activation. (nih.gov)