Loading...
  • hemoglobin
  • A macrocytic class of anemia is an anemia (defined as blood with an insufficient concentration of hemoglobin) in which the red blood cells (erythrocytes) are larger than their normal volume. (wikipedia.org)
  • Both of these factors work to the opposite effect of larger cell size, to finally result in a total blood hemoglobin concentration that is less than normal (i.e., anemia). (wikipedia.org)
  • citation needed] Other disorders which cause macrocytosis without DNA replication problems (i.e., non-megaloblastic macrocytic anemias), are disorders associated with increased red cell membrane surface area, such as pathologies of the liver and spleen which produce codocytes or "target cells" which have a central collection of hemoglobin surrounded by a pallor (a thin area) then followed by a thicker collection of hemoglobin at the rim of the cell. (wikipedia.org)
  • CDA is one of many types of anemia, characterized by ineffective erythropoiesis, and resulting from a decrease in the number of red blood cells (RBCs) in the body and a less than normal quantity of hemoglobin in the blood. (wikipedia.org)
  • Hemolysis
  • Also, rapid blood replacement from the marrow after a traumatic blood loss, or rapid red blood cell turnover from rapid hemolysis (G6PD deficiency), also often produces mild macrocytosis in the associated anemia. (wikipedia.org)
  • symptoms
  • Hypochromic anemia was historically known as chlorosis or green sickness for the distinct skin tinge sometimes present in patients, in addition to more general symptoms such as a lack of energy, shortness of breath, dyspepsia, headaches, a capricious or scanty appetite and amenorrhea. (wikipedia.org)
  • occurs
  • Anemia occurs when there are insufficient red blood cells, or they don't function properly. (drugs.com)
  • bone
  • citation needed] Classically, these megaloblastic types of anemias are associated also with more specific features, such as megaloblasts in the bone marrow, the presence of ovalocytes in the (peripheral) blood smear, and the pathognomonic presence of hypersegmented neutrophils. (wikipedia.org)
  • disorder
  • To generate funds for the charitable and scientific purpose of furthering the knowledge of the disorder known as Diamond Blackfan Anemia (DBA). (causes.com)
  • disorders
  • There are over 6,000 reported rare disorders and Diamond Blackfan Anemia is one of the rarest of the rare. (causes.com)