AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaHumanitiesInformation ScienceNamed GroupsHealth CareGeographicals
American Native Continental Ancestry GroupAsian Continental Ancestry GroupAfrican Continental Ancestry GroupEuropean Continental Ancestry GroupOceanic Ancestry GroupAsian AmericansGenealogy and HeraldryPolymorphism, Single NucleotideGenetics, PopulationAsiaGenome-Wide Association StudyGenotypeHaplotypesGene FrequencyAfrican AmericansIndians, South AmericanGene PoolGenetic Predisposition to DiseaseEthnic GroupsGenetic VariationPhylogenyGenetic LociTrinidad and TobagoLinkage DisequilibriumAllelesGenome, HumanPrincipal Component AnalysisAsia, SoutheasternGenetic MarkersHispanic AmericansChromosomes, Human, YHuman MigrationJewsPopulation GroupsHapMap ProjectEmigration and ImmigrationEuropeDNA, MitochondrialGenetic Association StudiesGeographyCase-Control StudiesFar EastEvolution, MolecularFounder EffectAfricaContinental Population GroupsHawaiiBiological EvolutionModels, GeneticGene Flow
WhitesEthnic GroupsGenetic ancestryHispanicIndividual'sEthnicityPolymorphismPopulationsNative AmericanTraitsAlgorithmDescriptorHumansRacialNucleotideDescentEvaluateMortalityInformativeSystematicEuropeanIndividualsAncestralPopulationAdmixtureCharacteristicsQuantitativeRaceDifferencesPerceptionsEastSystemVarious groupsHigherStructure
Whites2
  • Compared with whites, other racial and ethnic groups were on average younger and had a higher median score on the National Institutes of Health Stroke Scale. (elsevierpure.com)
  • Whites had higher 30-day unadjusted mortality than other groups (white versus black versus Hispanic versus Asian=15.0% versus 9.9% versus 11.9% versus 11.1%, respectively). (elsevierpure.com)
Ethnic Groups2
  • To evaluate the possibility that such differences are accompanied by differences in brain structure, we conducted a large comparative study on cognitively matched young and old adults from two cultural/ethnic groups - Chinese Singaporeans and non-Asian Americans - that involved a total of 140 persons. (illinois.edu)
  • Subjects identified themselves as belonging to one of four major racial/ethnic groups (white, African American, East Asian, and Hispanic) and were recruited from 15 different geographic locales within the United States and Taiwan. (blogspot.com)
Genetic ancestry6
  • From ∼ 1000 individuals of a founder population in Quebec, we reveal a substantial impact of the environment on the transcriptome and clinical endophenotypes, overpowering that of genetic ancestry. (nature.com)
  • Air pollution impacts gene expression and pathways affecting cardio-metabolic and respiratory traits, when controlling for genetic ancestry. (nature.com)
  • In order to determine a new subject's genetic ancestry, Parabon Snapshot analyzes tens of thousands of SNPs from a DNA sample to determine a person's percent membership in each of these global populations. (parabon-nanolabs.com)
  • We developed a framework for inference of germline variants from tumor panel sequencing, including imputation, quality control, inference of genetic ancestry, germline polygenic risk scores, and HLA alleles. (biomedcentral.com)
  • We showcase the feasibility and utility of our framework by analyzing 25,889 tumors and identifying the relationships between genetic ancestry, polygenic risk, and tumor characteristics that could not be studied with conventional on-target tumor data. (biomedcentral.com)
  • Worldwide, its incidence has increased progressively over the last a result of genetic ancestry. (cdc.gov)
Hispanic3
  • 3060 non-Hispanic Asian Americans, 1.5%) from 926 US centers participating in the Get With The Guidelines-Stroke program from April 2003 through December 2008. (elsevierpure.com)
  • After risk adjustment, Asian American patients with AIS had lower 30-day and 1-year mortality than white, black, and Hispanic patients. (elsevierpure.com)
  • Results: Among the 70,221 included patients, 91.3% were white, 3.8% were black, 3.4% were Hispanic, and 1.5% were of Asian/Native American/Pacific Islander race. (elsevierpure.com)
Individual's3
  • Using all of this information, Snapshot builds a precise profile of an individual's ethnic ancestry using only his or her DNA. (parabon-nanolabs.com)
  • In an ancestry analysis, Snapshot will determine an individual's precise genetic origins, as well as whether there is any evidence of admixture (contribution from multiple populations). (parabon-nanolabs.com)
  • The number of ancestral groups, K, is chosen to produce a best estimate of these probabilities, which are averaged over all genetic markers to assign a membership coefficient, namely a fraction of each individual's ancestry to one of the ancestral groups (Feldman 2010. (thisviewoflife.com)
Ethnicity2
  • On the other hand, we detected only modest genetic differentiation between different current geographic locales within each race/ethnicity group. (blogspot.com)
  • Thus, ancient geographic ancestry, which is highly correlated with self-identified race/ethnicity-as opposed to current residence-is the major determinant of genetic structure in the U.S. population. (blogspot.com)
Polymorphism2
  • After attributing a regional and/or continental ancestry to each individual using genome-wide polymorphism data, we are able to capture the effect of different environmental exposures on gene expression and health-related traits, while simultaneously controlling for genetic relatedness and migration. (nature.com)
  • The polymorphism was present as an insertion in cells derived from a group of Japanese individuals, but was completely absent (a deletion) in others, albeit with a lower frequency (hence called the minor allele). (fatsoflife.com)
Populations7
  • The population frequency of the indel (rs66698963) is remarkably different among human populations with the insertion being far more frequent in South Asians, Africans and some East Asian populations, and far less common in European and other East Asian populations. (fatsoflife.com)
  • Most other forensic ancestry systems use only a small number of SNPs and thus are limited to very coarse populations and cannot detect admixture between populations. (parabon-nanolabs.com)
  • Parabon's scientists have collected data from many published scientific articles, totalling more than 9,000 individuals with clearly defined ancestry from more than 150 populations around the world, as shown in the map below. (parabon-nanolabs.com)
  • Academic research using hundreds of thousands of SNPs from across the genome has shown that human groups generally divide into seven continental populations, which have been established over the past 50,000 years during the migration out of Africa. (parabon-nanolabs.com)
  • The 150 populations collected as the ancestry background can thus be divided into these seven continental groups according to their origin. (parabon-nanolabs.com)
  • Snapshot takes a similar approach to identifying within-continental (regional) ancestry, although the local populations were identified through empirical analysis performed by our bioinformatics team. (parabon-nanolabs.com)
  • Because of extensive admixture among these various groups, the Brazilian population shows great variability in terms of Populations on different continents vary considerably in their skin pigmentation, phenotypic features, and genomic structure [2]. (cdc.gov)
Native American1
  • Latino ancestry is a mixture of European and Native American ancestry, so these groups are shown as well. (parabon-nanolabs.com)
Traits2
  • Ethnic ancestry is one of the most informative traits that can be predicted from DNA. (parabon-nanolabs.com)
  • We report a fixed-effect, inverse-weighted-variance meta-analysis from 10,074 PCOS cases and 103,164 controls of European ancestry and characterisation of PCOS related traits. (ox.ac.uk)
Algorithm2
  • After global ancestry is determined, Snapshot's ancestry algorithm investigates which subpopulations (e.g. (parabon-nanolabs.com)
  • STRUCTURE is an algorithm designed to infer population structure (cluster individuals into ancestry groups) within a species (Pritchard, Stephens, and Donnelly 2000. (thisviewoflife.com)
Descriptor1
Humans1
  • According to Nicholas Wade, "Humans cluster into five continental groups or races, and within each race there are further subclusters. (thisviewoflife.com)
Racial1
  • After risk-adjustment, there was no difference in the rates of in-hospital mortality, myocardial infarction, stroke, major bleeding, vascular complications, or new pacemaker requirements among the 4 racial groups. (elsevierpure.com)
Nucleotide1
  • STRUCTURE produces for individuals an estimate of the probability that a randomly chosen genetic marker (e.g. single tandem repeats, STR, or single nucleotide polymorphisms, SNP) from that individual originated from one of a set of ancestral groups. (thisviewoflife.com)
Descent2
  • Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent. (ox.ac.uk)
  • The term Afro-Latinx (or Afro-Latino, -Latina, or -Latine) refers to individuals of Latin America or of Latin American descent who are also of African ancestry. (loc.gov)
Evaluate1
  • Data were technically validated using published algorithms to evaluate donor relatedness, ancestry, imputed HLA, and T1D genetic risk score. (nature.com)
Mortality2
  • This is the first study to examine the association between ambient air pollution (PM2.5, O3, and NO2) and mortality (in different population groups by sex and age) based on a nationwide death record across Brazil over a 15-year period (2003-2017). (bvsalud.org)
  • 6.72) increase in the risk of circulatory mortality for the group of women, all ages. (bvsalud.org)
Informative1
  • Model-based clustering and ancestry informative markers analyses suggested that this is due to taurine introgression. (biomedcentral.com)
Systematic2
  • Although a large part of South American zebu cattle also descend from taurine cows, we did not detect significant levels of taurine ancestry in these breeds, probably because of systematic backcrossing with zebu bulls. (biomedcentral.com)
  • CONCLUSION: Our data indicate that most T2D-risk variants identified in Europeans have similar effects in South Asians from Sri Lanka, and that systematic difference in common variant associations are unlikely to explain inter-ethnic differences in prevalence or presentation of T2D. (ox.ac.uk)
European6
  • Global ancestry map showing mostly East Asian and Native/South American ancestry, with some European ancestry as well. (parabon-nanolabs.com)
  • For example, the admixed East Asian and Latino example from the global map above was determined to have specifically Japanese, Central American, and Southwest European ancestry, as shown in the map below. (parabon-nanolabs.com)
  • Regional ancestry map showing mostly Japanese, Southwest European, and Central American ancestry. (parabon-nanolabs.com)
  • Each piece of continental ancestry is partitioned according to its regional ancestry (e.g., if an individual is 50% European and 50% East Asian, the precise origin of each of those pieces will be determined). (parabon-nanolabs.com)
  • INTRODUCTION: Most studies seeking common variant associations with type 2 diabetes (T2D) have focused on individuals of European ancestry. (ox.ac.uk)
  • Conclusions: Our results indicate that European ancestry is a risk factor for cutaneous melanoma. (cdc.gov)
Individuals3
  • Drawing from this founding population of individuals with largely French ancestry, we selected 1007 individuals to determine mechanisms by which genomes, the environment, and their interactions contribute to phenotypic variation. (nature.com)
  • Snapshot uses tens of thousands of SNPs across the genome to obtain very precise estimates of ancestry, even for admixed individuals. (parabon-nanolabs.com)
  • The ancestral groups are not specified in advance, and the population membership of individuals is removed prior to analysis. (thisviewoflife.com)
Ancestral1
  • These discoveries need to be evaluated in other major ancestral groups, to understand ethnic differences in predisposition, and establish whether these contribute to variation in T2D prevalence and presentation. (ox.ac.uk)
Population8
  • The population frequency of the allele corresponding to the rs66698963 insertion (allele named I) or deletion (allele named D) was determined from genomic DNA extracted from human samples (blood, breast milk, and placenta) obtained from several participating institutions in the US and Canada (n=211, nearly all from Kansas City), as well as from a group of Asian Indians (n=76). (fatsoflife.com)
  • Each point represents a population from which we have obtained ancestry background data. (parabon-nanolabs.com)
  • This study aims to establish whether common variants conferring T2D-risk in Europeans contribute to T2D-susceptibility in the South Asian population of Sri Lanka. (ox.ac.uk)
  • The direction, statistical significance, and effect size of these associations varied considerably by type of air pollutant, region, and population group (sex and age group). (bvsalud.org)
  • In particular, the older population group (>65 years) was most affected. (bvsalud.org)
  • The Indo-Guyanese population is one of the fastest growing immigrant groups in North America (1) and the largest immigrant minority population in Schenectady, New York. (cdc.gov)
  • DISCUSSION: In addition to reporting the prevalence of use in this important group of potential users, we outline important sociodemographic risk factors for hookah use in a non-Arab American population. (who.int)
  • The NHANES II sample was selected so that certain population groups thought to be at high risk of malnutrition (persons with low incomes, preschool children and the elderly) were oversampled. (cdc.gov)
Admixture1
  • This analysis is robust to admixture, such that each piece of continental ancestry can be precisely localized within that continent. (parabon-nanolabs.com)
Characteristics2
  • We grouped patients according to examined LN number (1-15 and 16+) and compared characteristics. (houstonmethodist.org)
  • From the abstract: 'Precision prevention involves using the unique characteristics of a particular group to determine their responses to preventive interventions. (cdc.gov)
Quantitative1
  • A very important new article by a group of Greek and Chinese researchers provides the first quantitative assessment of mental processing in two groups of students, aged 8 to 14, belonging to the Caucasoid and Mongoloid races. (blogspot.com)
Race1
  • Recent genetic research indicates that the degree of genetic heterogeneity within groups and homogeneity across groups make race per se a less compelling predictor. (bvsalud.org)
Differences1
  • However, group differences were evident when high-performing old were compared. (illinois.edu)
Perceptions1
  • METHODS: Using data from 6 focus groups among ESL instructors and students, we characterized perceptions about activities that are successfully used in ESL classrooms and strategies for delivering hepatitis B information. (fhcrc.org)
East4
  • There is an emergent literature suggesting that East Asians and Westerners differ in cognitive processes because of cultural biases to process information holistically (East Asians) or analytically (Westerners). (illinois.edu)
  • Our data suggest that survival of Korean-American gastric cancer patients are comparable with outcomes from East Asian hospitals and may be independent of surgical technique. (houstonmethodist.org)
  • Below is an example plot for an individual who was determined to be 50% East Asian and 50% Latino. (parabon-nanolabs.com)
  • Most Indo-Guyanese trace their ancestry to the mid-1800s, when (East) Indian indentured servants were brought to Guyana, an English-speaking, continental West Indian country formerly known as British Guiana (1). (cdc.gov)
System2
  • Assessments used the Radiation Therapy Oncology Group scoring system for acute RT skin reaction (RTOG scale). (cancerindex.org)
  • Parabon has built a powerful system for determining ethnic ancestry from DNA. (parabon-nanolabs.com)
Various groups1
  • This pseudoscience is technically not the same as racism , which is the belief that one or more of these various groups is "superior" or "inferior" to one or more others, usually in some vague, undefined way. (rationalwiki.org)
Higher1
  • It has long been known that many Mongoloid groups generally have higher IQ scores than Caucasoids, but the reasons for this difference have not been explained. (blogspot.com)
Structure1
  • In order to obtain unbiased assessments of genetic differentiation and structure in taurine and zebu cattle, we analyzed a dataset of 135 AFLP markers in 1,593 samples from 13 zebu and 58 taurine breeds, representing nine continental areas. (biomedcentral.com)