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  • CCX168
  • The secondary objectives of this study include assessment of the feasibility of reducing or eliminating the use of corticosteroids in the treatment of subjects with ANCA-associated vasculitis without the need for rescue corticosteroid measures and the effect of CCX168 on several disease parameters. (clinicaltrials.gov)
  • diseases
  • In reality, therefore "ANCA" now refer to an increasing number of autoantibodies directed against targets within neutrophils and are associated, in general with clinically different, although often overlapping, diseases. (bmj.com)
  • Primary
  • A careful systems review and physical examination will help determine whether the investigation should move in the direction of primary (acquired) GN or toward multisystem disease associated with GN ( Table 472-1 ). (mhmedical.com)