• As the fetus relies on the placenta for not only nutrition, but many other developmentally essential functions, the correct development of the placenta is important to correct embryonic and fetal development. (edu.au)
  • Because the fetal development occurs over the course of several months, critical structures may be affected at various periods. (psychologic.science)
  • Importantly, a precise temporal description of RPRM protein expression during the development of neuronal structures is still missing. (frontiersin.org)
  • The evolutionary process is intimately linked to the embryonic development. (bcbl.eu)
  • First, I will focus on the differential contribution of external glutamatergic populations to the development of the dorsal pallium, the embryonic structure that generates the neocortex. (bcbl.eu)
  • Osteoderms are composed of bone tissue , and are derived from a scleroblast neural crest cell population during embryonic development of the organism. (wikipedia.org)
  • But by studying embryonic development, we can gain insight into why and how these two structures resemble one another. (abdn.ac.uk)
  • Our finding that these structures develop from a common pool of cells suggests otherwise - that gills and fins share a much deeper and more substantial evolutionary relationship that is reflected in their embryonic development. (abdn.ac.uk)
  • The presence of estradiol in developing ovarian follicles usually inhibits spermatogonia development in adjacent or contralateral seminiferous tubules. (medscape.com)
  • Approaches to scaffolding technology that were discussed at the meeting ranged in complexity from tissue repair products consisting of bovine type 1 collagen knee implants to the highly complex such as the use of whole acellular lung matrix (ACM) to support the development of engineered lung tissue from embryonic stem cells. (genengnews.com)
  • Early in development, the anterior portion of the neural tube has three distinct vesicles, which will each develop into different structures. (msu.edu)
  • Through development, the walls of these vesicles will differentiate into adult brain structures. (msu.edu)
  • Differentiation is the process by which structures become more complex and functionally specialized during development. (msu.edu)
  • Abnormalities in embryonic development that result in birth defects are likely to involve the disruption of many cellular signaling cascades that would usually direct normal embryonic development. (nih.gov)
  • 10. The Sugar Code forms information-rich structures that influence the arrangement of different cell types during embryological development. (catsboard.com)
  • In the nineteenth and twentieth centuries, the development of new microscopic and molecular techniques, including DNA sequencing, enabled scientists to confirm the hypothesis that chromosomes determine the sex of developing organisms. (asu.edu)
  • CT scanning can give valuable information regarding the anatomical and mechanical contributions in the development of acute sinusitis. (medscape.com)
  • During the third week of embryonic development, proliferation and medial migration of ectodermal cells form the notochord. (medscape.com)
  • Anatomical homologies - Throughout the domains of life, organisms show a distinct pattern of constraints based on homology in the development and construction of the body. (rationalwiki.org)
  • Embryology - The pharyngula stage of embryonic development appears to be highly conserved. (rationalwiki.org)
  • The glans penis develops as the terminal end of the genital tubercle during the embryonic development of the male fetus. (simonewhitehead.co.uk)
  • Cell and tissue specific gene expression is a defining feature of embryonic development in multi-cellular organisms. (biomedcentral.com)
  • There are several reasons for choosing Drosophila melanogaster as an organism for the global study of gene expression during embryonic development. (biomedcentral.com)
  • the process that governs the early embryonic patterning of the Drosophila body plan is now the best understood example of a complex cascade of transcriptional regulation during development [ 14 , 15 ]. (biomedcentral.com)
  • Biologist regularly use C. elegans to gain insight into topics ranging from embryonic development and aging to genetics and neurobiology. (discovermagazine.com)
  • This is according to new research from Tufts University scientists which shows that long before movement or other behaviors occur, the brain of an embryonic frog influences muscle and nerve development and protects the embryo from agents that cause developmental defects. (medindia.net)
  • To examine the role of the brain during early development, the researchers removed the brains of Xenopus laevis frog embryos 27-1/2 hours after the eggs were fertilized, long before independent embryonic activity occurs. (medindia.net)
  • The pituitary gland is entirely ectodermal in origin but is composed of 2 functionally distinct structures that differ in embryologic development and anatomy: the adenohypophysis (anterior pituitary) and the neurohypophysis (posterior pituitary). (medscape.com)
  • After the heart tube and pericardium have rotated from the cranial position to lie anteriorly, the notochord, which is initially in the caudal region of the embryonic disc, rotates to lie posterior to the primitive foregut. (medscape.com)
  • The tubercle is present in the embryos of both sexes as an outgrowth in the caudal region that later develops into a primordial phallus. (simonewhitehead.co.uk)
  • In the zebrafish, rprma mRNA is expressed in the olfactory placodes (OP) and olfactory epithelium (OE), rprmb is observed in the tectum opticum (TeO) and trigeminal ganglion (Tg), whereas rprml is found primarily in the telencephalon (Tel). At protein level, RPRM is present in a subset of cells in the OP, and neurons in the OE, TeO, hindbrain and sensory peripheral structures. (frontiersin.org)
  • The connectome - an anatomical map of links between neurons - is insufficient to reconstruct the way the nervous system works in practice. (discovermagazine.com)
  • This involves transplantation of developing midbrain cells from aborted fetuses, (the part that form mesDA neurons), into the striatum of a PD patient. (lu.se)
  • A potentially pre-clinical aspect of this thesis is detailed in paper №4 where I describe a robust protocol for the generation of functional mesDA neurons from human embryonic stem cells that are functional in a rat model of PD. (lu.se)
  • Here, we describe in detail the spatiotemporal expression of three rprm genes ( rprma, rprmb , and rprm l) within distinct anatomical structures in the developing peripheral and central nervous system. (frontiersin.org)
  • Dr Sleight commented: "Although the distinct embryonic origin of the gill arches and paired fin skeleton is widely assumed, it has never been formally tested in fishes. (abdn.ac.uk)
  • Chordates are a phylum of animals that possess a distinct set of anatomical features at some stage in their life cycle. (thenoveldifference.com)
  • Anatomical entity that comprises the animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. (xenbase.org)
  • One is a method for in vitro differentiation of thyrocytes and 3D culture of follicles starting from mouse embryonic stem cells. (unil.ch)
  • Using diabetic mice in vivo and high glucose-treated primary ENPCs in vitro, the effects of L-Fucose on the injured ENS and ENPCs was evaluated by assessing gastrointestinal motility, ENS structure, and the differentiation of ENPCs. (bvsalud.org)
  • The neurohypophysis develops from the differentiation of neural ectoderm into the pars nervosa, the infundibular stem, and the median eminence. (medscape.com)
  • Fins come from a population of cells called mesoderm while the gill arches develop from a population called neural crest. (abdn.ac.uk)
  • Such human fully integrated and complete SEMs recapitulate the organization of nearly all known lineages and compartments of post-implantation human embryos, including the epiblast, the hypoblast, the extra-embryonic mesoderm and the trophoblast layer surrounding the latter compartments. (nature.com)
  • These include embryonic disc and bilaminar disc formation, epiblast lumenogenesis, polarized amniogenesis, anterior-posterior symmetry breaking, primordial germ-cell specification, polarized yolk sac with visceral and parietal endoderm formation, extra-embryonic mesoderm expansion that defines a chorionic cavity and a connecting stalk, and a trophoblast-surrounding compartment demonstrating syncytium and lacunae formation. (nature.com)
  • Mouse naive embryonic stem cells have recently been shown to give rise to embryonic and extra-embryonic stem cells capable of self-assembling into post-gastrulation structured stem-cell-based embryo models with spatially organized morphogenesis (called SEMs) 3 . (nature.com)
  • We determined and documented embryonic expression patterns for 6,003 (44%) of the 13,659 protein-coding genes identified in the Drosophila melanogaster genome with over 70,000 images and controlled vocabulary annotations. (biomedcentral.com)
  • The workings of stem cells within the testicles are not well understood in mammals, though a few genes have been linked to stem cell self-renewal in the fruit fly, which has a simpler anatomical structure. (sciencedaily.com)
  • But that changed in the early 21st century when scientists developed a set of techniques for switching genes on and off with light. (discovermagazine.com)
  • Here we extend those findings to humans using only genetically unmodified human naive embryonic stem cells (cultured in human enhanced naive stem cell medium conditions) 4 . (nature.com)
  • The researchers went on to show that another protein, OCT4, which functions to maintain the stem cells in the early embryo and in cultured embryonic stem cells, is also present in the adult germ stem cell. (sciencedaily.com)
  • Among these is the isolation of the first line of murine stem cells [ 5 , 6 ] in 1981, followed by establishment of the first human embryonic stem cell lines by Thompson [ 7 ]. (intechopen.com)
  • In the early embryo, embryonic stem cells give rise to all of the cell types in the organism, including adult stem cells, which continually replace cells in the adult tissues that die or differentiate into more mature cells like red blood cells. (sciencedaily.com)
  • Coronary sinus, normally located between the LEFT ATRIUM and LEFT VENTRICLE on the posterior surface of the heart, can serve as an anatomical reference for cardiac procedures. (bvsalud.org)
  • Students study the morphological structures and 3D relationships of the musculoskeletal, cardiopulmonary, and gastrointestinal systems. (unthsc.edu)
  • The placenta is a mateno-fetal organ which begins developing at implantation of the blastocyst and is delivered with the fetus at birth. (edu.au)
  • The innate and adaptive immune defenses of the developing fetus are poorly equipped to fight infections. (edu.au)
  • The timing of the alcohol exposure will determine the variations of the anatomical effects in the developing fetus. (psychologic.science)
  • In the brain, changes in the developing program ruling the formation of the brain produced the anatomical and functional divergences present across vertebrate taxa. (bcbl.eu)
  • Some anatomical structures in the developing embryo disappear completely or regress substantially once they serve their developmental purpose, remaining only as scar-like vestiges (literally, "footprints") in the mature human. (answersingenesis.org)
  • The fundamental information provided by GUDMAP will serve as a baseline for developing new strategies for repair or replacement of damaged organs, for understanding organogenesis and the etiology of congenital malformations, and for generating insights into pathologic processes underlying developmental defects and disease. (nih.gov)
  • Furthermore, embryonic developmental factors are emerging as important participants in adult regenerative and repair processes. (nih.gov)
  • These progenitors which are derived from either embryonic stem cells (ESCs) or healthy induced pluripotent stem cells (iPSCs) express wild-type levels of a-syn, thus making them equally susceptible to developing Lewy bodies over time. (lu.se)
  • The dorsal hollow nerve cord is a neural tube that develops into the central nervous system. (thenoveldifference.com)
  • Do human embryos replay the evolutionary history of their species as they develop? (answersingenesis.org)
  • Do developing embryos really replay the evolutionary history of their species as they develop? (answersingenesis.org)
  • By studying embryos of the skate, a cartilaginous fish closely related to sharks, Dr Sleight and Dr Gillis found that gill arches develop from both neural crest and mesodermal cells - what is known as dual origin. (abdn.ac.uk)
  • Although it is possible to culture structures derived from human blastocysts ex vivo, these cultures do not recapitulate the events and structural organization of the in vivo embryos 6 ( Supplementary Information ). (nature.com)
  • In addition, when exposed to chemicals that do not cause birth defects in normal embryos, embryos without brains developed severe deformities, such as bent spinal cords and tails. (medindia.net)
  • The GUDMAP consortium has established a molecular anatomy atlas of the developing murine kidney and the lower urinary tract. (nih.gov)
  • They are considered homologous structures because they have similar underlying anatomy. (knowexamples.com)
  • And the basic rule of homologous structures is that homologous structures have the same skeletal anatomy but have different purposes. (knowexamples.com)
  • The hyaloid canal appears to have no function in the adult eye, though its remnant structure can be seen. (turningtooneanother.net)
  • This important finding confirms earlier published studies suggesting that the adult germ stem cells are not far removed from embryonic stem cells. (sciencedaily.com)
  • Thus, a comprehensive understanding of how organs develop in the embryo is necessary to effectively interrogate maladaptive processes and understand regeneration. (nih.gov)
  • Chordates and non-chordates exhibit significant differences in their anatomical structures and physiological processes. (thenoveldifference.com)
  • Genetic and molecular analyses have led to a deep understanding of many embryonic processes in this animal [ 8 ]. (biomedcentral.com)
  • Students develop processes to understand, analyze, and critique current research articles in biomedical sciences. (unthsc.edu)
  • Mesenchyme that is part of a developing pinna [Automatically generated definition]. (mcw.edu)
  • While directing expression in a broad range of anatomical structures in the embryo, the majority of the 75 enhancers directed expression to various regions of the developing nervous system. (ox.ac.uk)
  • The ectoderm layer is what will develop into the nervous system. (msu.edu)
  • Let's focus on the ectoderm that will develop into the nervous system. (msu.edu)
  • The structures of the central nervous system will form from the walls of the neural tube and the lumen of tube will become the ventricles of the brain and central canal of the spinal cord. (msu.edu)
  • Modelling these interdependencies will reveal the computational rules embedded in the structure of C. elegans' nervous system. (discovermagazine.com)
  • The course covers how the nervous system develops, its structure and how it functions. (lu.se)
  • Here we report that 45% of these sequences functioned reproducibly as tissue-specific enhancers of gene expression at embryonic day 11.5. (ox.ac.uk)
  • This occurs during the embryonic period of gestation or around the third and fourth weeks after conception. (psychologic.science)
  • Homology occurs when very different animals have bones or other structures that appear very similar in form but not in function. (knowexamples.com)
  • As a major divergence, the neocortex governs the mammalian brain with its unique six-layered structure. (bcbl.eu)
  • [1] The armadillo osteoderm is believed to develop in subcutaneous dermal tissues. (wikipedia.org)
  • Embryo-like models with spatially organized morphogenesis and structure of all defining embryonic and extra-embryonic tissues of the post-implantation human conceptus (that is, the embryonic disc, the bilaminar disc, the yolk sac, the chorionic sac and the surrounding trophoblast layer) remain lacking 1 , 2 . (nature.com)
  • Much of this process relies on the morphogenesis of the extra-embryonic tissues and the effect this has on the organization of embryonic cells. (nature.com)
  • In this talk I will present the latest results of our group in the search of those singular events by comparing the early developing brain of mouse and chick. (bcbl.eu)
  • Your eyes and vision are fully developed when you reach your early 20s. (turningtooneanother.net)
  • In the bitch, things become even more difficult when we realize that apparent infertility can be due to very different situations which prove difficult to distinguish, such as lack of fertilization (no union between eggs and sperm) and early embryonic death. (vin.com)
  • Work developed in the Department of Human Embryology, Faculty of Medicine of Marília, Marília, São Paulo. (bvsalud.org)
  • The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures. (virtualflybrain.org)
  • Anatomical structures of great complexity seem to begin as much simpler forms. (answersingenesis.org)
  • There is no similar structure in other species, which brings the question as to what singular evolutionary mechanisms enabled neocortical origin. (bcbl.eu)
  • Future research will focus on decoding the specific information being sent through the newly identified communication channels from the brain, identifying other body structures that require brain presence, exploring relevance in other species, and honing the ability to provide brain-like signals in other contexts to improve complex patterning and tissue repair. (medindia.net)
  • The structures are however derived from scutes , common to all classes of amniotes and are an example of what has been termed deep homology . (wikipedia.org)
  • In homology, the organ or bone with similar underlying anatomical traits is found in different animals. (knowexamples.com)
  • Understanding the embryonic origin of gill arches and paired fins sheds light on their possible evolutionary relationship. (abdn.ac.uk)
  • It was previously believed that comparative anatomist Carl Gegenbaur's theory that paired fins evolved from gill arches couldn't be possible as these structures develop from two distinctly different sets of cells in the embryo. (abdn.ac.uk)
  • Tissue engineers working at the laboratory for stem cells and tissue engineering at Columbia University's Fu Foundation School of Engineering are applying a biomimetic approach to developing tissue replacements. (genengnews.com)
  • Veins are tubular collections of cells transporting deoxygenated blood and waste products from capillaries Capillaries Capillaries are the primary structures in the circulatory system that allow the exchange of gas, nutrients, and other materials between the blood and the extracellular fluid (ECF). (lecturio.com)
  • The Allen Discovery Center at Tufts focuses on reading and writing the morphogenetic code that orchestrates how cells communicate to create and repair complex anatomical shapes and includes researchers from Tufts, Harvard, Princeton, the University of Chicago and Tel Aviv University. (medindia.net)
  • However, patient-derived cells may be more prone to develop disease-associated pathology after grafting. (lu.se)
  • This discovery reveals a previously unrecognised embryonic continuity between gill and fin skeletons, and explains the anatomical similarities that led Gegenbaur to propose an evolutionary relationship between these structures nearly 150 years ago. (abdn.ac.uk)
  • From an anatomical perspective, we can look at two structures that loosely resemble one another, like the skeletons of gills and fins, and speculate that one might have undergone an evolutionary transformation into the other. (abdn.ac.uk)
  • From these mesodermal structures the branchial arches develop, the first of which gives rise to internal nasal structures. (medscape.com)
  • There are several examples of homologous structures such as the leg of a cat, an arm of a human, the leaves of a pitcher plant, and a wing of a bird, etc. (knowexamples.com)
  • A flipper of a dolphin is a homologous structure like a human limb, the wings of a bird, etc. the flipper of a dolphin or whale and a human limb, also the wing of the bird have different purposes, but are similar and share common traits. (knowexamples.com)
  • Other homologous structures to the human arm are the flipper of a whale, the wing of a bird, and the leg of a cat. (knowexamples.com)
  • Abnormalities can range from anatomical associated with degree or site of inplantation, structure (as with twinning), to placental function, placento-maternal effects (pre-eclampsia, fetal erythroblastosis) and finally mechanical abnormalities associated with the placental (umbilical) cord. (edu.au)
  • Non-chordates encompass a wide range of animal phyla, exhibiting diverse body plans, anatomical structures, and ecological roles. (thenoveldifference.com)
  • These different structures are also homologous to the wings of the bat, the arms of people, and the other animal parts described above. (knowexamples.com)
  • The notochord is a flexible rod-like structure that serves to support vertebrate bodies while acting as its precursor. (thenoveldifference.com)
  • A critical distinction between chordates and non-chordates lies in their body structures - chordates have a spinal cord or backbone, whereas non-chordates lack it and contain notochord. (thenoveldifference.com)
  • 19] The rich innervation of the glans penis reveals its function as a primary anatomical source of male sexual pleasure. (simonewhitehead.co.uk)
  • Using the Virtual Knife slicing tool in the NetOStat brain atlas browser, a researcher can manipulate the view of this 3D anatomical data set over the Internet. (epmba.org)
  • By studying cellular structures and mechanisms, researchers gain insights into how different systems operate at a microscopic level. (filosofia-internet.net)
  • specifically, differences in iodine organification cannot be modelled in 2D cell cultures, because it requires the 3D structure of the normal anatomical units of the thyroids, the sphere-shaped follicles. (unil.ch)
  • Homologous structure means a similar structure that evolved from a common ancestor. (knowexamples.com)
  • These structures support the idea that the different animals originated from a common ancestor and it is proof or evidence of evolution . (knowexamples.com)
  • Biologists have evidence that all life developed from a common ancestor that lived just under 4 billion years ago, and virtually all scientists in the field accept the concept. (rationalwiki.org)
  • Through meticulous research, scientists have been able to unlock the mysteries behind various diseases and develop innovative therapies. (filosofia-internet.net)
  • At the same time, scientists have developed ways to automate the measurements of neural activity in vastly parallel experiments. (discovermagazine.com)
  • This means, they have the same skeletal structure, and they perform different functions. (knowexamples.com)
  • A developing embryo changes its shape dramatically as it morphs into its mature form. (answersingenesis.org)
  • in contrast, the neurohypophysis develops from the infundibulum, which is a downward extension of neural ectoderm from the floor of the diencephalon (see the image below). (medscape.com)
  • A: Infundibulum and Rathke's pouch develop from neural ectoderm and oral ectoderm, respectively. (medscape.com)