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  • Abstract
  • Study on the obtaining of transgenic wheats with GNA alien gene by biolistic particle, Scientia Agricultura Sinica (in Chinese with English abstract), 2001, 34 (1): 1-4. (springer.com)
  • structural
  • By our predictions and analysis, both of the PpseOBPs share some similar physicochemical and structural characteristics with insect classic OBP genes, but they do not strictly observe the cysteine pattern of OBPs in insects, in which there are three amino acid residues between the second and the third cysteine residues but 27 amino acid residues in P. pseudoannulata . (springer.com)
  • RNA-sequencing (RNA-seq) data from eight equine tissue samples (34-day whole embryo, full term placental villous, adult testes, adult cerebellum, adult articular cartilage, adult LPS-stimulated articular cartilage, adult synovial membrane, and adult LPS-stimulated synovial membrane) were used to refine the structural annotation of protein-coding genes in the horse and for a preliminary assessment of tissue-specific expression patterns. (biomedcentral.com)
  • A consensus set of equine protein-coding gene structures was defined by consolidation of gene sets predicted by Ensembl and NCBI (containing 20,322 and 17,610 genes respectively) and structural annotation derived from the RNA-seq experiments. (biomedcentral.com)
  • Gene ontology annotation was used to evaluate the functional and structural categories of genes expressed in either a stable or tissue-restricted pattern. (biomedcentral.com)
  • PhenoFam provides a user-friendly, easily accessible web interface to perform GSEA based on high-throughput data sets and structural-functional protein information, and therefore aids in functional annotation of genes. (biomedcentral.com)
  • In recent years, access to high-resolution protein structural information has increased considerably. (biomedcentral.com)
  • inhibitory
  • 5 These proteins interact with several diverse proteins implicated in transcription and exert inhibitory effects through suppression of the DNA-binding activity of a transcription factor, enrollment of other co-regulators, or enhancing the sumoylation of a transcription factor. (dovepress.com)
  • tissues
  • METHODS: Pulp tissues were subjected to reverse transcription-polymerase chain reaction (PCR) detection for transporter isoforms belonging to organic anion transporting polypeptide (Oatp), organic anion transporter (Oat), organic cation transporter (Oct), multidrug resistance-associated protein (Mrp), and multidrug resistance protein (Mdr) families. (biomedsearch.com)
  • Comprehensive qRT-PCR analysis found various expression patterns for MdFKBP s in different tissues and in plant responses to water-deficit and salt stresses. (biomedcentral.com)
  • novel
  • Transgene inheritance and quality improvement by expressing novel HMW glutenin subunit (HMW-GS) genes in winter wheat, Chinese Science Bulletin, 2003, 48(8): 771-776. (springer.com)
  • Analysis of homology data also allows for comprehensive re-annotation of T3SS loci within Desulfovibrio, Lawsonia and Hahella, and subsequent comparison of these T3SSs with related Yersinial T3SSs, and also (in conjunction with in vitro assays) for identification of many novel effectors in E. coli. (bham.ac.uk)
  • Addgene: Newsletter Hot Plasmids Michael Lin and colleagues at Stanford University have deposited plasmids encoding novel cas9 proteins that enable light regulated gene editing or activation of. (educoo.us)
  • functional
  • Our tool is designed to analyse complete sets of results from quantitative high-throughput studies (gene expression microarrays, functional RNAi screens, etc .) without prior pre-filtering or hits-selection steps. (biomedcentral.com)
  • These results offer a roadmap for further functional characterizations of the protein factors, and for building models when testing the genetic contributions of these genes in plant growth and development. (biomedcentral.com)
  • The occurrence of similar CATGCATG consensus cis elements with alternating purine and pyrimidine base pairs in front of several other plant genes suggests a functional role of the motif in a wider range of plant promoters. (deepdyve.com)
  • suggests
  • Our research suggests that introducing wblrp gene into wheat is an effective way to improve its nutrition quality. (springer.com)
  • The highly conserved tubby domain in different species suggests that these proteins must have fundamental biological functions in multicellular organisms. (plantphysiol.org)
  • The plot of ENC values and GC3s as well as the correlation between base composition and codon usage bias suggests that mutational pressure rather than natural selection is the main factor that determines the codon usage bias in the VP2 gene. (deepdyve.com)
  • Apis
  • Forêt S, Maleszka R (2006) Function and evolution of a gene family encoding odorant binding-like proteins in a social insect, the honey bee ( Apis mellifera ). (springer.com)
  • transcription
  • It encodes a simple transcription unit of two exons, encoding a 541 aa protein. (biomedcentral.com)
  • Protein inhibitors of activated STAT (PIAS) are transcription co-regulator of the Janus kinase/signal transducer and activator of transcription signaling pathway as well as nuclear factor-κB family of transcription factors. (dovepress.com)
  • sequences
  • Overlapping loci from the two gene sets were analyzed by calculating the intersection and union of their respective coding (exon) sequences to determine if they represented the same gene. (biomedcentral.com)
  • These proteins all feature an approximately 270-amino acid tubby domain at their C-terminal region, but their N-terminal sequences are more divergent both in length and in amino acid sequences. (plantphysiol.org)
  • Membrane
  • Gene Expression Analysis of Membrane Transport Proteins in Normal and Lipopolysaccharide-inflamed Rat Dental Pulp. (biomedsearch.com)
  • INTRODUCTION: Membrane transport proteins (transporters) play a crucial role in the transmembrane uptake and/or efflux of various compounds such as inorganic ions, endogenous bioactive substances such as prostaglandins (PGs), and drugs such as nonsteroidal anti-inflammatory drugs. (biomedsearch.com)
  • showed that mouse TUBBY is transported from the plasma membrane to the nucleus after phospholipase C- β activation of a subclass of G proteins called G α q . (plantphysiol.org)
  • mNeonGreen was also used successfully to trace endogenous proteins, and label specific subcellular compartments such as the nucleus or the plasma membrane. (g3journal.org)
  • regulate
  • G protein−coupled receptors (GPCRs) regulate facets of growth, development, and environmental sensing in eukaryotes, including filamentous fungi. (g3journal.org)
  • cellular processes
  • Collectively these results point to deregulation of cellular processes, such as metabolism and protein synthesis, consistent with the observed elevated oxidative stress levels in DNMC potentially resulting in oxidative DNA damage in these cells. (hindawi.com)
  • pathway
  • Engineering of the aspartate family biosynthetic pathway in barley ( Hordeum vulgare L.) by transformation with heterologous genes encoding feed-back-insensitive aspartate kinase and dihydrodipicolinate synthase, Plant Mol. (springer.com)
  • determine
  • Deleted derivatives of this legumin upstream sequence were fused to the npt‐ll reporter gene to determine the tissue‐specific activity of the chimeric constructs in stably transformed tobacco plants. (deepdyve.com)
  • We assessed the PRNP gene by whole-exome sequencing in 264 pathologically confirmed MSA cases and 462 healthy controls to determine whether the 2 diseases share similar risk factors. (ucl.ac.uk)
  • To determine amino acid subsequences likely to be important for function, we have compared the protein sequence of several species. (springer.com)
  • genomic
  • First, the genomic locus data and intervals for the genes predicted by Ensembl and NCBI were combined. (biomedcentral.com)
  • All three databases want the same end result: a richly annotated, biologically and computationally sound record, one that allows other scientists to be able to reap the benefits of the work already performed by the submitting biologist and that affords links to the protein, bibliographic, and genomic databases (see Chapter 7). (booksbw.com)
  • silico
  • In silico analysis of several of the conserved components of T3SSs shows similarities between them and other secretion systems, as well as components of ATPases. (bham.ac.uk)
  • researchers
  • Later it was established that these proteins have physico-chemical properties similar to those of ovalbumin (storage egg-white protein) or serum albumin (major protein of serum) which are typical albunoid proteins and therefore researchers have proposed to rename major royal jelly proteins as apalbumins. (biomedcentral.com)
  • Results
  • Results suggested that some genes which had not been taken into account in the original study could have an important role in the processes causing, or affected by, pulmonary fibrosis. (upc.edu)
  • PhenoFam utilizes Ensembl databases to link a list of user-provided identifiers with protein features from the InterPro database, and assesses whether results associated with individual domains differ significantly from the overall population. (biomedcentral.com)
  • Analysis of large sets of results derived from high-throughput experiments is a challenging but promising field of study. (biomedcentral.com)
  • Previous studies investigated the association of G-protein β 3 (GNB3) genetic polymorphisms with FD but with inconsistent results. (hindawi.com)
  • publicly available
  • In this contribution a network-based candidate gene prioritization strategy was applied to the enrichment of a publicly available gene expression dataset, focused on the study of the mechanosensitivity of genes exposed to altered pulmonary matrix stiffness. (upc.edu)
  • When comparing the gene expression profiles extracted from publicly available microarray datasets, some of the polyadenylation related genes showed tissue-specific expression, suggestive of potential different polyadenylation complex configurations. (biomedcentral.com)
  • patterns
  • This study represents a comprehensive analysis of IBDV VP2 gene codon usage patterns and provides a basic understanding of the codon usage bias. (deepdyve.com)
  • NCBI
  • Sequin is also an ASN.1 editing tool that takes full advantage of the NCBI data model (see Chapter 2) and has become a platform for many sequence analysis tools that NCBI has developed over the years. (booksbw.com)
  • play
  • Olfaction is crucial for insect behaviors such as feeding, mating and foraging, and odorant-binding proteins (OBPs) play a vital role in smell sensing, so we suppose that OBPs may be also important in spider behaviors. (springer.com)
  • In mammals, TUBBY-like proteins play an important role in maintenance and function of neuronal cells during postdifferentiation and development. (plantphysiol.org)
  • The FK506-binding proteins (FKBPs) play diverse roles in numerous critical processes for plant growth, development, and abiotic stress responses. (biomedcentral.com)
  • transgenic
  • Analysis of transgenic plant lines of T 2 by Northern dot-blotting showed good expression of wblrp gene in offspring seed. (springer.com)
  • The content of free lysine in leaves, contents of bound lysine and total proteins in seeds of T 2 transgenic wheat lines were determined and analyzed. (springer.com)
  • Transfer of high lysine-rich gene into maize by microprojectile bombardment and detection of transgenic plants, J. Agri. (springer.com)
  • Transfer of Lysine-rich protein gene into rice and production of fertile transgenic plants, Acta Botanica Sinica, 2001, 43 (5): 506-511. (springer.com)
  • Wobus, Ulrich 1992-01-01 00:00:00 A 2.4 kb fragment containing the 5 ‐flanking region and the 5′‐noncoding sequence of the Vicia faba legumin gene LeB4 mediates high level seed‐specific expression in transgenic tobacco plants. (deepdyve.com)
  • study
  • In a recent study, the utility of the Roche xCELLigence System was explored for assessing RNAi-mediated knockdown of gene function. (technologynetworks.com)
  • The present study provides evidences for altered expression of PIAS genes in IFNβ-treated MS patients compared with healthy subjects. (dovepress.com)
  • In the present study, we have analyzed the relative synonymous codon usage and effective number of codons (ENC) using 69 IBDV VP2 genes. (deepdyve.com)
  • Thus
  • Thus, when the tree-building analysis based on the alignment is followed, one should consider whether other evolutionary relationships might be favored using a slightly modified alignment. (booksbw.com)
  • diverse
  • Unlike the highly diverse N-terminal region of animal TUBBY-like proteins, all AtTLP members except AtTLP8 contain a conserved F-box domain (51-57 residues). (plantphysiol.org)
  • Use of conserved components allows for identification of T3SS loci in diverse bacteria, in order to assess in the different proteins used by different T3SSs, and to see where, in evolutionary space, these differences arose. (bham.ac.uk)
  • Neurodegenerative diseases are a very diverse group of disorders but they share some common mechanisms such as abnormally misfolded proteins with prion-like propagation and aggregation. (ucl.ac.uk)
  • plant
  • An extensive protein network was revealed for plant polyadenylation machinery, in which all predicted proteins were found to be connecting to the complex. (biomedcentral.com)
  • The largest predicted GPCR class in these organisms is the Pth11-related, with members similar to a protein required for disease in the plant pathogen Magnaporthe oryzae . (g3journal.org)
  • However
  • However, a convenient tool that combines these two features to aid in high-throughput data analysis has not been developed yet. (biomedcentral.com)
  • However, for fluorescent proteins, this also means lower signal intensities, which can only be compensated by using brighter fluorescent proteins. (g3journal.org)