Analysis of complete genomes. Medical search. Frequent questions

We sequenced the complete mt genome of W. compar and conducted phylogenetic analyses using concatenated coding sequences of 12 protein-coding genes (PCGs) by maximum likelihood and Bayesian inference. (nature.com)
The complete mt genome is 14,373 bp in size and comprises 36 genes, including 12 protein-coding, two rRNA and 22 tRNA genes. (nature.com)
About 2000 completely sequenced mitochondrial genomes are available from the NCBI RefSeq data base together with manually curated annotations of their protein-coding genes, rRNAs, and tRNAs. (scienceopen.com)
The genomes contained numerous genes that encode siderophore receptors, but no evidence of siderophore production was found, suggesting that they may obtain iron via interaction with other microorganisms. (nih.gov)
Virulence genotype analysis revealed that strain CR1 lacked hemolytic phospholipase C and D, three genes for LPS biosynthesis and had reduced antibiotic resistance genes when compared with clinical strains. (frontiersin.org)
Comparison with Streptomyces coelicolor A3(2) revealed that an internal 6.5-Mb region in the S. avermitilis genome was highly conserved with respect to gene order and content, and contained all known essential genes but showed perfectly asymmetric structure at the oriC center. (elsevierpure.com)
The S. purpurea mt genome contains 52 genes: 31 protein-coding, 18 tRNAs, and three rRNAs. (springeropen.com)
In addition, these findings provide further support for models in which conflicts between different genes in genomes can drive the process of speciation. (elifesciences.org)
A total of 134 genes were identified in the cp genome of S. tetrandra, including 87 protein - coding genes , 8 rRNA genes , 37 tRNA genes and 2 pseudogene copies (ycf1 and rps19). (bvsalud.org)
Comparative analysis of the Stephania cp genomes revealed 5 highly variable regions, including 3 intergenic regions (trnH-psbA, trnD-trnY, trnP) and two protein coding genes (rps16 and ndhA). (bvsalud.org)
Phylogenetic tree analysis based on the conserved chloroplast protein coding genes indicated a sister relationship between S. tetrandra and the monophyletic group of S. japonica and S. kwangsiensis with high support values, suggesting a close genetic relationship within Stephania plants . (bvsalud.org)
The International Mouse Phenotyping Consortium (IMPC) is aiming to produce a complete catalogue of mammalian gene function across all genes. (sciencedaily.com)
Their initial results, now published in Nature Genetics , is based on an analysis of the first 3,328 genes (15 per cent of the mouse genome coding for proteins). (sciencedaily.com)
When C. sakazakii SP291 was compared to the reference C. sakazakii ATCC BAA-894, which is also of PIF origin, the annotated genome data identified two interesting functional categories, comprising of genes related to the bacterial stress response and resistance to antimicrobial and toxic compounds. (northumbria.ac.uk)
That's comparable to the number of genes many scientists now think the human genome contains. (sciencenews.org)
The application of fluorescence in situ hybridization for the mapping of genes and sequences, as well as comparative analyses of genome homology by comparative genomic hybridization will be useful tools for understanding the genomic changes in relation to evolutionary processes such as speciation and adaptation to different environments. (karger.com)
Current diagnostic PCR assays target a variety of SARS CoV-2 genes and the vast majority target sequences in regions of the SARS CoV-2 genome that are highly conserved. (who.int)

In this study, we investigated the presence of DuCV in northern Vietnam, and furthermore, conducted molecular characterization of identified DuCV strains based on the complete genome. (researchsquare.com)
Characterization of La Crosse virus small genome transcripts. (microbiologyresearch.org)

It is a matter of concern that the Human reference genome originally developed in 2003[ 1 ] is derived from about 200 anonymous individuals from six countries: China, France, Germany, Great Britain, Japan and the United States, but did not have Deoxyribonucleic Acid (DNA) from any Indian. (ijpsonline.com)
With affordable technology and accessible reference genome database, analyzing individual genome has become feasible to understand one's health and associated health related risk factors. (ijpsonline.com)
The secondary analysis is the steps done from sequencing down to expression values have been generated, including demux and alignment against a reference genome. (lu.se)

Here we present the whole genome sequence analysis of an individual from the Kashmir region of India who is from the pandit community (IHGP04). (ijpsonline.com)
In this context, we have recently reported a complete sequence analysis of a male from the Western part of The contemporary Indian population is an admixture of several waves of human migration from various directions, which is believed to have been segregated into various communities over the past 2000 y or so[ 2 ]. (ijpsonline.com)

A complete mitochondrial genome sequence of Ogura-type male-sterile cytoplasm and its comparative analysis with that of normal cytoplasm in radish (Raphanus sativus L. (biomedcentral.com)

Complete genomic sequences of 12 different coronavirus strains demonstrated that the viral structure, with small irrelevant mutations, was stable in the transmission chains and showed remarkable traits of infectious traceability. (ersjournals.com)
The L protein of Rift Valley fever virus can rescue viral ribonucleoproteins and transcribe synthetic genome-like RNA molecules. (microbiologyresearch.org)
Little genetic drift was detected in viruses shed by the same subjects following repeated reactivation events, suggesting strong selective pressure on the viral genome to maintain sequence fidelity during reactivations from its latent state within an individual host. (emmes.com)
We used next-generation sequencing techniques to determine whole-genome sequences of four viral samples from two subjects in the Herpevac Trial. (emmes.com)
Only 19 genetic polymorphisms unique to the primary or recurrent isolate were identified, 10 in subject A and 9 in subject B. These observations indicate remarkable genetic conservation between primary and recurrent episodes of HSV-2 infection and imply that strong selection pressures exist to maintain the fidelity of the viral genome during repeated reactivations from its latent state. (emmes.com)
Viral proteins are synthesized, and the viral genome is copied by a viral RNA polymerase (see the image below). (medscape.com)
The laboratory service is available for Swedish healthcare givers and contract costumers round-the-clock every day of the year for analysis of specimens from patients suspected to be infected with a high consequence viral pathogen that pose a danger to society. (folkhalsomyndigheten.se)
The laboratory is always operational, and within two hours of notification from a healthcare facility, laboratory staff can initiate analyses of samples suspected to contain viral haemorrhagic fever viruses such as Ebola and Marburg viruses. (folkhalsomyndigheten.se)
1/f correlations in viral genomes--a Fast-Fourier Transformation (FFT) Study. (who.int)

A new genetic databank has been established containing the completed whole-genome sequencing (WGS) data of close to 5,000 Singaporeans. (medicalxpress.com)
We present an in silico approach for the reconstruction of complete mitochondrial genomes of non-model organisms directly from next-generation sequencing (NGS) data-mitochondrial baiting and iterative mapping (MITObim). (scienceopen.com)
We undertook whole genome sequencing of E. faecalis associated with bloodstream infection in the UK and Ireland over more than a decade to determine the population structure and genetic associations with hospital adaptation. (nature.com)
Microbial genome sequencing provides the opportunity to gain a detailed understanding of the molecular basis for hospital adaptation. (nature.com)
CHICAGO (GenomeWeb) - A little more than a year after launching a genome-sequencing effort, a high-performance computing facility at a Scottish university has analyzed more than 6,000 human genomes, and has been processing more than 600 a month of late. (genomeweb.com)
The article focused on the sequencing technology that will soon enable a full scan of a human genome for $1000, and to make the story come alive, I decided to go through the process myself. (discovermagazine.com)
The Baylor team has been intimately involved in many of the most important advances of genome sequencing over the last decade. (discovermagazine.com)
Once the Human Genome Project was completed, researchers were eager to start sequencing individual human beings, and to examine the genetic variations that define each individual's traits and quirks. (discovermagazine.com)
If the cost of sequencing a genome had continued at $3 billion a pop, there would be no way to conduct such experiments. (discovermagazine.com)
When the sequencing was complete, Watson flew down to Houston. (discovermagazine.com)
Another genetics pioneer, Craig Venter , was also sequencing his personal genome at the same time, but the Baylor team says Watson's was completed first. (discovermagazine.com)
In 2011, whole-genome sequencing revealed not only the genetic variants responsible, it also revealed which neurotransmitters were affected, and suggested a new drug regimen that worked remarkably well to control the twins' symptoms. (discovermagazine.com)
Whole-genome sequencing aims to provide complete analysis of an organism's genome. (nanoporetech.com)
The technique allows subsequent reassembly of the genome sequence and identification of novel variants and genomic structures that would be missed by targeted sequencing approaches. (nanoporetech.com)
however, the development of modern sequencing techniques, such as nanopore sequencing, now enable every researcher to benefit from comprehensive and cost-effective whole-genome characterisation of their samples of interest. (nanoporetech.com)
Whole-genome sequencing has been instrumental in many research areas, from identifying novel disease-associated variation in humans, plants, and animals, to tracking microbial outbreaks such as SARS-CoV-2. (nanoporetech.com)
Why nanopore technology for whole-genome sequencing? (nanoporetech.com)
A wide range of library preparation kits are available to suit all whole-genome sequencing requirements. (nanoporetech.com)
Amplification-based kits are also available, enabling whole-genome sequencing from low input amounts or poor-quality DNA (e.g. (nanoporetech.com)
Get best practice recommendations to optimise your end-to-end whole-genome sequencing workflow in our Getting started guides. (nanoporetech.com)
View all of our whole-genome sequencing resources, including white papers, case studies, best practice workflows, and more. (nanoporetech.com)
Which device for whole-genome sequencing? (nanoporetech.com)
From portable, yet powerful Flongle and MinION devices, suitable for microbial genomes, through to the flexible GridION device and high-output PromethION devices, ideal for large eukaryotic genomes - scale your sequencing to match your specific whole-genome sequencing requirements. (nanoporetech.com)
They combined a variety of approaches including protein sequencing, amino acid composition and a complete RNA reference database for mass spectrometry analysis. (scienceblog.com)
With the development of next generation sequencing (NGS) technologies, such as the Roche and Illumina platforms, new strategies are being used to characterize plant mitochondrial genomes. (springeropen.com)
2015 ), have been successfully assembled through a combination approach using shotgun and paired-end NGS sequencing from non-enriched whole genome DNA libraries. (springeropen.com)
Sequencing of the 3′ and 5′ termini of the BUNdelNSs S RNA segment and analysis using a minireplicon system show that the N overexpressing phenotype results from a single nucleotide substitution at position 16 in the 3′ terminus. (microbiologyresearch.org)
During my time in SOKENDAI I've been studying ancient human genomes as well single-cell RNA-sequencing in zebrafish. (soken.ac.jp)
For whole-genome sequence assembly and finishing, the Optical Mapping System is complementary to existing second- and forthcoming third-generation sequencing technologies, he said, in that it can provide a complete genome scaffold for contig alignment and orientation. (genomeweb.com)
Decreases in genome sequencing costs have driven a proliferation in the volume of genomic data. (uic.edu)
In particular, rates of bacterial genome sequencing have accelerated, due to low sequencing costs. (uic.edu)
Each of the HSV-2 genome sequences was initially obtained using next-generation sequencing and completed with Sanger sequencing. (emmes.com)
Remarkable advancement in next generation sequencing technology has made personal genome analysis feasible and affordable. (ijpsonline.com)
Newborn screening in the genomics era: are we ready for genome sequencing? (cdc.gov)
Thus, the research programme gene or genome-wide genotyping of GCS complements that of GEP, studies, as well as sequencing work. (who.int)
CDC used whole genome sequencing (WGS) analysis to link one case to contaminated opened powdered formula from the patient's home and the other to contaminated breast pump equipment. (medscape.com)
Primary analysis is the base calling performed by the Illumina software during the sequencing. (lu.se)
#546 ) Confirm sequencing as completed. (lu.se)

Gene reduction analysis revealed that the gene deletion processes are under selective pressure, and many of the inactivations are probably related to the organism's interaction with its host environment. (asm.org)
2005). "Extensive DNA inversions in the B. fragilis genome control variable gene expression" (PDF). (wikipedia.org)
The Edinburgh Parallel Computing Centre is handling data analysis and storage of gene sequences, leaving the scientific operations to the scientists on each campus. (genomeweb.com)
Thirty gene clusters related to secondary metabolite biosynthesis were identified, corresponding to 6.6% of the genome. (elsevierpure.com)
Plant mitochondrial (mt) genomes possess several complex features, including a variable size, a dynamic genome structure, and complicated patterns of gene loss and gain throughout evolutionary history. (springeropen.com)
The gene order and GC content were highly consistent in the Stephania species according to the comparative analysis results, with the highest RSCU value in arginine (1.79) and lowest RSCU value in serine of S. tetrandra, respectively. (bvsalud.org)
The project involves going through the mouse genome systematically and knocking out a particular gene, one by one, in different mice. (sciencedaily.com)
In this thesis, I present a novel genome data visualization targeting an important area of genomics research: comparative bacterial gene neighborhood analysis. (uic.edu)
In this thesis, I present Bacterial Gene Neighborhood Investigation Environment, or BactoGeNIE, a new comparative gene neighborhood visualization designed to address large volumes of bacterial genome sequences and explore the design decisions that best take advantage of large, high-resolution environments. (uic.edu)
My high-density genome data visualization approach relies on interactive visual queries to transform large data volumes into high-resolution comparative genomic maps, that use pre-attentive visual cues to address analytic tasks for comparative gene neighborhood investigations across large volumes of complete bacterial genomes. (uic.edu)
1) BactoGeNIE is a novel visualization design that is the first scalable visualization for comparative analysis of hundreds to thousands of gene neighborhoods. (uic.edu)
Genome-wide scans localized the disease phenotype to chromosome 8q, a region harboring RP1, a gene previously implicated in the pathogenesis of RP. (molvis.org)
Gene expression analyses of foraminifera common to severely hypoxic or anoxic sediments identified metabolic strategies used by this abundant taxon. (lu.se)
We have studied the presence of long-range correlations in the complete genomes of ten different dsDNA viruses and Saccharomyces cerevisiae (bakers' yeast) chromosome I. We have also studied the correlation between the distribution of the gene length and the domain of "1/f region" of their genomes. (who.int)

Celera, the Rockville, Md., company that sequenced the human genome, also completed a mouse genome, but researchers need to pay a subscription fee to access the data. (sciencenews.org)

Cytogenet Genome Res (2014) 142 (2): 107-111. (karger.com)
Cytogenet Genome Res (2010) 128 (1-3): 77-87. (karger.com)

To further investigate the genomic diversity among this group and to help characterize lineages of the plague organism that have no sequenced members, we present here the genomes of two isolates of the "classical" antiqua biovar, strains Antiqua and Nepal516. (asm.org)
To date, a lack of the Vietnamese DuCV strains in GenBank and systemic analysis were performed to elucidate the genetic characteristics of the Vietnamese DuCV strains. (researchsquare.com)
The complete genomes of three strains from the phylum Acidobacteria were compared. (nih.gov)
It clustered with the outlier group, hence we scaled up the analyses to understand the differences in environmental and clinical outlier strains. (frontiersin.org)
We have determined the complete nucleotide sequences of 10 new NLV strains. (edu.sa)
When the distance distribution analysis was performed, the polymerase-based classification did not separate the strains into internal clusters within the genogroup. (edu.sa)
Furthermore, a diversity plot analysis of the complete nucleotide sequences of WUG1, a NLV GI strain, and Saitama U1, a NLV GII strain, indicated that the genotype was different between the polymerase and capsid N/S domain, suggesting that these strains are the genetic recombinants. (edu.sa)

The complete nucleotide sequence of the mitochondrial genome for the Senegal sole Solea senegalensis Kaup was determined. (unboundmedicine.com)
We have determined the complete nucleotide sequence of the linear chromosome of Streptomyces avermitilis. (elsevierpure.com)

Recent molecular analyses of mt genome sequences have provided selectable hypotheses for the phylogenetic relationships of nematodes based on 18S rRNA. (nature.com)
Kumar S, Stecher G, Tamura K (2016) MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets. (springer.com)
Complete chloroplast genome of Stephania tetrandra (Menispermaceae) from Zhejiang Province: insights into molecular structures, comparative genome analysis, mutational hotspots and phylogenetic relationships. (bvsalud.org)
In addition, the species relationship within Stephania genus still remains uncertain due to high morphological similarity and low support values of molecular analysis approach. (bvsalud.org)
In addition, five pairs of specific primers targeting the divergence regions were accordingly designed, which could be utilized as potential molecular markers for species identification, population genetic and phylogenetic analysis in Stephania species. (bvsalud.org)
Molecular Evolution of Herpes Simplex Virus 2 Complete Genomes: Comparison between Primary and Recurrent Infections. (emmes.com)
C.P. tion stage, why much more detailed molecular analysis is contributed to the design of the study, discussions on statistical analysis of called for [2]. (lu.se)

The approach overcomes the limitations of traditional strategies for obtaining mitochondrial genomes for species with little or no mitochondrial sequence information at hand and represents a fast and highly efficient in silico alternative to laborious conventional strategies relying on initial long-range PCR. (scienceopen.com)
In this study, we undertook extensive genome-wide comparative analyses of twelve species that conform the Pectobacterium genus. (mdpi.com)
strain CF27, new sequences were generated, and an update assembly and functional annotation were undertaken, followed by a comparative analysis with other Acidithiobacillus species whose genomes are publically available. (frontiersin.org)
The array of techniques applied to analysis of a mussel foot showed that a species-to-species variation exists in mussel, including unusual variation in the protein. (scienceblog.com)
Our analysis contributes toward understanding the organization and evolution of organelle genomes in Salicaceae species. (springeropen.com)
2015 ). Plant mt genomes can be extraordinarily larger than animal mt genomes, and vary significantly in size, even between very closely related species or within a single family (Alverson et al. (springeropen.com)
Here we identify causes underlying hybrid infertility of two recently diverged fission yeast species Schizosaccharomyces pombe and S. kambucha , which mate to form viable hybrid diploids that efficiently complete meiosis, but generate few viable gametes. (elifesciences.org)
The complete chloroplast (cp) genome data has become a promising strategy to determine geographical origin and understand species evolution for closely related plant species. (bvsalud.org)
Herein, we sequenced the complete cp genome of S. tetrandra from Zhejiang Province and conducted a comparative analysis within Stephania plants to reveal the structural variations, informative markers and phylogenetic relationship of Stephania species. (bvsalud.org)
Overall, we provided comprehensive and detailed information on the complete chloroplast genome and identified nucleotide diversity hotspots of Stephania species. (bvsalud.org)
In evaluating the genome data currently available for Cronobacter species, no sequence information has been published describing a Cronobacter sakazakii isolate found to persist in a PIF production facility. (northumbria.ac.uk)
Near-complete expression of a diatom's plastid genome in one foraminiferal species suggests kleptoplasty or sequestration of functional plastids, conferring a metabolic advantage despite the host living far below the euphotic zone. (lu.se)

Although the S. purpurea chloroplast genome has been published (Carlson et al. (springeropen.com)

We make a fingerprint of the DNA, of the whole genome, that we can then put into our database and we can compare it with other isolates. (genomeweb.com)
Patient isolates and environmental samples were sent to CDC, state public health laboratories, and other federal agencies for isolation, identification, and WGS analysis of C. sakazakii . (medscape.com)

Genome Insider: Methane Makers in Yosemite's Lakes Meet researchers who sampled the microbial communities living in the mountaintop lakes of the Sierra Nevada mountains to see how climate change affects freshwater ecosystems, and how those ecosystems work. (doe.gov)
Hongoh Y (2010) Diversity and genomes of uncultured microbial symbionts in the termite gut. (springer.com)
We think there's a significant [opportunity] for the microbial market," White said, but, he added, the company targeted less complex genomes for the initial launch of the Argus system for practical reasons. (genomeweb.com)

We identified eight new regions of genomic plasticity and a plasmid pCR1 with a VirB/D4 complex followed by trimeric auto-transporter that can induce virulence phenotype in the genome of strain CR1. (frontiersin.org)

However, the vast majority of the mouse genome remains poorly understood, as scientists tend to focus their research on a few specific areas of the genome linked to the most common inherited diseases. (sciencedaily.com)
This is why the IMPC is aiming to build a complete database that systematically details the functions of all areas of the mouse genome, including neurological, metabolic, cardiovascular, respiratory and immunological systems. (sciencedaily.com)
It may not mean much to Wall Street investors, but researchers worldwide were delighted to hear on May 6 that the mouse genome had finally gone public. (sciencenews.org)
The mouse genome is about 15 percent smaller than the human genome, according to the geneticists. (sciencenews.org)
Another mouse genome has been available for about a year, but not for free. (sciencenews.org)

These data extend our understanding of the genome of this important neonatal pathogen and provides further insights into the genotypes associated with features that can contribute to its persistence in the PIF environment. (northumbria.ac.uk)
Centre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton, England, United Kingdom of Great Britain and Northern Ireland. (who.int)

We are proud to work together with the leading biotech company in Sweden for biomarker panel analyses in epidemiology, OLINK Proteomics AB, Uppsala, and its representatives! (lu.se)

Adaptation and conservation insights from the koala genome. (genome.jp)
Studies of plant mt genomes can, therefore, provide unique insights into organelle evolution. (springeropen.com)

But with two projects, communities are forming to generate high quality genomes to benefit researchers. (doe.gov)
It had taken an army of researchers about 13 years and $3 billion to accomplish the task, but finally the researchers had the sequence of about 3 billion nucleotides, the complete genetic code for a human being. (discovermagazine.com)
By averaging the variations between these genomes, the researchers came up with their best approximation of what it means to be a healthy, functional person. (discovermagazine.com)
Using OpGen's MapSolver software, contigs generated by sequencers are mapped in silico "so that the contigs can be mapped back to the complete ordered optical map scaffold of DNA, giving researchers the ability to very rapidly orient the sequence data to help accelerate assembly and finishing," he said. (genomeweb.com)
The mouse researchers plan to publish their formal analysis of the genome later this year. (sciencenews.org)
Researchers have completed a quest that started 32 years ago, having uncovered the final DNA sequences that make up a human genome. (genome.gov)
The Human Genome Project ended in 2003, but genomic researchers had not yet determined every last base (or letter) of the human genome sequence. (genome.gov)

Those structural differences popped into clear view through computer analysis of more than 500 linear feet of DNA molecules analyzed by the powerful genome mapping system developed over nearly two decades by David C. Schwartz, professor of chemistry and genetics at UW-Madison. (scienceblog.com)

Silver Age of GOLD Introduces New Features The Genomes OnLine Database makes curated microbiome metadata that follows community standards freely available and enables large-scale comparative genomics analysis initiatives. (doe.gov)

It takes 40 hours to analyze a complete genome at the EPCC. (genomeweb.com)
The integrative building process included studying the behavior of fluids at microscopic scale, manipulating large DNA molecules and placing barcodes on them, automating high-powered microscopes to analyze single molecules, organizing the computing infrastructure to handle the data and algorithms to analyze whole human genome, and more. (scienceblog.com)

Polymorphisms over the entire genomes were mapped, and amino acid variants resulting from nonsynonymous changes were analyzed based on the secondary and tertiary structures of a previously crystallized protein. (emmes.com)

A review of surveys conducted to date reveals considerable variation in both the choice and use of survey methods and in the assumptions made in the analysis and interpretation of findings. (who.int)

MITOS: improved de novo metazoan mitochondrial genome annotation. (scienceopen.com)

Genetic may be conferring genetic susceptibility analysis comprises either candidate to cancer. (who.int)

We sequenced and constructed the complete genome of an environmental strain CR1 of P. aeruginosa and performed the comparative genomic analysis. (frontiersin.org)

We move around 400 terabytes of data around every week, and, if we keep all of the genomes we process, we will store several petabytes of data every year," Parsons said. (genomeweb.com)
The computing center also handles data processing for the Scottish Genomes Partnership, a collaboration announced in January 2015 between the University of Edinburgh, the University of Glasgow, and the National Health Service Scotland. (genomeweb.com)
The Illumina HiSeq X machines produce raw genome sequence data, which is then copied over via the university network to EPCC's supercomputer and stored on the DDN file systems, Parsons explained, and the computing center then creates the variant calling files. (genomeweb.com)
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We generated the mt genome sequence from 454 pyrosequencing whole genome big data. (springeropen.com)
It and BGI, OpGen said, had already used the technology to complete a study based on human genome data to successfully close gaps in existing sequence folds. (genomeweb.com)
One area that the company is focusing on is using the technology to arrive at high resolution analysis of an isolate and then using that data to compare the isolate with others that are associated with a public health outbreak. (genomeweb.com)
Thousands of complete genome sequences have been compiled on public databases and even larger volumes of data have been generated privately by independent research groups. (uic.edu)
While automated analysis plays a significant role in the generation and analysis of this data, visualization is needed to bring experts into the data-mining loop, to verify the results of automated analysis and to detect patterns that are difficult to find through computation alone. (uic.edu)
These environments present an opportunity to visualize big data in new ways and better integrate expert judgment in the computational analysis of big data. (uic.edu)
Recent research suggests that big displays present benefits to visualization designers and enable the analysis of complex data sets. (uic.edu)
The Indian male's genome was sequenced at 38.6 X coverage with a total of 110 Gb of sequence data generated using the Illumina HiSeq 2000 platform. (ijpsonline.com)
Subsequently, significant work has been done on Indian genomes but not much variant data from the Indian population has been added to the human genome variant database[ 2 - 7 ]. (ijpsonline.com)
The reference Human Genome and related variant databases need to be enriched with data from underrepresented populations. (ijpsonline.com)
However, most GEP studies have typically been performed on whole tissue samples, containing varying degrees of tumor cell content, which results in uncertainties in data analysis. (lu.se)
GEN's projects usual y involve extensive may have a larger effect than common fieldwork in col aboration with external single-nucleotide polymorphisms but investigators in order to develop large- that are not sufficiently frequent to scale epidemiological studies with be captured by current genome-wide appropriate clinical and exposure data, association genotyping arrays. (who.int)
Alternative analysis of the data from a HPV vaccine study in India - Authors' reply. (who.int)

It combines approachable narrative with extensively tested lab exercises that illustrate key concepts of genome biology in humans, invertebrates, and plants. (cshlpress.com)
NEW YORK (GenomeWeb News) - As OpGen intensifies the commercialization of its optical mapping technology, it is looking to expand its use to larger genomes, including humans, within the next year, its CEO said. (genomeweb.com)
If all goes as planned, in the third quarter of 2011, OpGen will launch the system for whole-genome sequence assembly and finishing for research on larger organisms, such as plants and animals, including humans, CEO Doug White told GenomeWeb Daily News . (genomeweb.com)
Liu et al performed phylogenetic and recombination analyses on 31 complete HAV genomes from infected humans and simians. (medscape.com)

In addition, the team identified 98.3 million genetic variants across the Singapore genomes. (medicalxpress.com)
The variant analysis revealed over 3.6 million single nucleotide variants and 5 46 681 small insertions and deletions including about 2.7 % of novel (unreported) variants. (ijpsonline.com)
The analysis and validation of the novel variants and relationship with health and diseases should be the next logical step. (ijpsonline.com)
This approach has been to use genomic and typical y occurs within GEP, which bioinformatic techniques to complement has a primary interest in the analysis more traditional approaches for the study and identification of common genetic of rare genetic variants. (who.int)

After joining the JGI, he formed the Microscale Applications group to operate a similar single-cell genomics pipeline that provides JGI users access to the genomes of uncultured microbes. (doe.gov)

The greater overlap offered by long reads enhances genome assembly by providing longer continuous, unambiguously assembled sequences, resulting in fewer contigs. (nanoporetech.com)
1997 ). The comparative analysis of plant mt genomes enhances our understanding of genome rearrangement and DNA transfer mechanisms, and of phylogenetic diversity. (springeropen.com)

I could sit down with you and start at chromosome 1, and we could pan and zoom through each one and actually see the genetic changes across an individual's genome. (scienceblog.com)
Chromosome analysis using RBA-banding consistently revealed a 39,XXY karyotype. (karger.com)
and through the analysis of mitochondrial and Y-chromosome haplogroups decipher the migratory routes as well as the time for the ancestors of this individual to reach India. (ijpsonline.com)

Here we report on the complete genome sequence of one such isolate, Cronobacter sakazakii SP291 along with its phenotypic characteristics. (northumbria.ac.uk)

We determined the genome sequences of viruses isolated from two subjects in the Herpevac Trial for Women who experienced primary HSV-2 genital disease and compared them with sequences of viruses isolated from the subsequent fifth or sixth episode of recurrent disease in the same individuals. (emmes.com)

To get a better picture of those structural variations, Schwartz and his team developed the Optical Mapping System, a wholly new type of genome analysis that directly examines millions of individual DNA molecules. (scienceblog.com)
Common systems for analyzing genomes typically chop long DNA molecules into fragments less than a couple thousand base pairs long and multiply them en masse, like a copy machine, to develop a chemical profile of each piece. (scienceblog.com)
OpGen's Optical Mapping Technology is a method of deciphering a genome's architecture by creating high-resolution, ordered, whole-genome restriction maps from single DNA molecules. (genomeweb.com)

The comparative analysis of these genomes provides a new approach to the study of novel proteins and protein interactions. (uic.edu)

The mitochondrial (mt) genome has drawn increased attention during the genomic and now post-genomic eras owing to its maternal pattern of inheritance and unique evolutionary features, and is often used for the phylogenetic study of plants (Gualberto et al. (springeropen.com)
This cytogenetic diversity offers the opportunity to perform cytotaxonomic and phylogenetic studies, as well as structural, evolutionary, and functional analyses of the genome. (karger.com)

I will describe the program design and architecture, along with several examples from visualizing draft Escherichia coli (E. coli) genomes. (uic.edu)
Those scientists have now assembled the sequences, which cover more than 95 percent of the rodent's DNA, and made the draft genome available for free over the Internet. (sciencenews.org)

Chen L, Gu W, Xu H, Yang G, Shan X, Chen G, Wang CF, Qian AD (2018) Complete genome sequence of Bacillus velezensis 157 isolated from Eucommia ulmoides with pathogenic bacteria inhibiting and lignocellulolytic enzymes production by SSF. (springer.com)

In April of 2003, the federally funded Human Genome Project finished the first complete human genome. (discovermagazine.com)
The genome constructed by the Human Genome Project was a "consensus genome" made by combining the genetic material of a handful of people. (discovermagazine.com)

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Health Care4

Geographicals2

Genes17

Characterization2

Reference genome3

Sequence analysis2

Mitochondrial genome sequence1

Viral9

Sequencing38

Gene14

Sequenced the human genome1

Cytogenet Genome Res2

Strains7

Nucleotide sequence2

Molecular7

Species12

Chloroplast genome1

Isolates2

Microbial3

Phenotype1

Mouse genome5

Pathogen2

Proteomics1

Insights2

Researchers7

Genetics1

Microbiome1

Analyze2

Amino acid1

Reveals1

Annotation1

Comprises1

Genomic analysis1

Data20

Humans4

Variants4

Genomics1

Enhances2

Chromosome3

Isolate1

Subsequent1

Molecules3

Proteins1

Evolutionary2

Draft2

20181

Human Genome2