Analysis bacterial structures. Medical search. Frequent questions

In molecular biology, bacterial DNA binding proteins are a family of small, usually basic proteins of about 90 residues that bind DNA and are known as histone-like proteins. (wikipedia.org)
Since bacterial binding proteins have a diversity of functions, it has been difficult to develop a common function for all of them. (wikipedia.org)
in these processes, bacterial DNA binding proteins have an architectural role, maintaining structural integrity as transcription, recombination, replication, or any other DNA-dependent process proceeds. (wikipedia.org)
Upon further investigation, it was discovered that the amino acid composition of HU resembles that of eukaryotic histones, thus prompting further research into the exact function of bacterial DNA binding proteins and discoveries of other related proteins in bacteria. (wikipedia.org)
Initially, bacterial DNA binding proteins were thought to help stabilize bacterial DNA. (wikipedia.org)
Currently, many more functions of bacteria DNA binding proteins have been discovered, including the regulation of gene expression by histone-like nucleoid-structuring protein, H-NS. (wikipedia.org)

Although we did not find a particular species assemblage or community marker to distinguish infection risk on an individual sample level, we identified differences in bacterial community composition, diversity, and structure between clinically symptomatic and asymptomatic TIVAPs that could be explored further. (hal.science)
In recent years, microbial culturomics has been a culturing approach that uses multiple techniques, such as MALDi-TOF mass spectrometry and 16S rRNA sequencing, for the identification of bacterial species. (springeropen.com)
Ribosomal RNA analysis confirmed that filamentous cyanobacteria Phormidesmis priestleyi , also found in Antarctic lakes and marshes, is the predominant species contributing to granule formation and growth. (wattsupwiththat.com)
Analysis also showed that granule diameter surpassing 250μm due to growth of P. priestleyi leads to change of bacterium species inhabiting cryoconite granules. (wattsupwiththat.com)
The filamentous cyanobacterium Phormidesmis priestleyi was the dominant bacterial species in larger granules. (wattsupwiththat.com)
Structure of Co-expression Networks of Bifidobacterium species in Response to Human Milk Oligosaccharides. (openwetware.org)
Results 80 (66 viable) bacterial species were identified overall and 12 fungal (none viable). (bmj.com)
In 2002, an ad hoc committee for the reevaluation of species definition in bacteriology ( 24 ) advised that all new bacterial species descriptions include an rRNA sequence from the type strain, and in 2001, Bergey's Trust published a revised higher-order taxonomy attempting to reconcile bacterial taxonomy with rRNA-based phylogeny ( 12 , 13 ). (asm.org)
Current estimates of the number of bacterial species range from 1 to 1000 million. (lu.se)
16S sequencing is performed to determine which bacterial species are present in a clinical sample or isolate. (folkhalsomyndigheten.se)

H-NS is about 15.6 kDa and assists in the regulation of bacterial transcription in bacteria by repressing and activating certain genes. (wikipedia.org)
Now, new research has revealed syringelike structures produced by bacteria that induce this metamorphosis. (livescience.com)
he researchers have now identified that the bacteria produces syringelike structures similar to virus tails that appear to be the key to the bacteria's role in the tubeworm metamorphosis. (livescience.com)
Structure and function of the Q-type centers in Chloroflexus and purple bacteria, comparison with photosystem II. (elte.hu)
To confirm which media and which bacterial colony densities can enrich certain kinds of bacteria, we selected eight common media and used them to enrich the gut microorganisms on agar plates. (springeropen.com)
We investigated how the nutritional components and densities influence the composition and diversity of the bacterial community, which bacteria could be enriched and the conditions of nutritional composition or density that allowed enrichment, and what the interaction was among bacteria at various densities. (springeropen.com)
Bacteria often switch from a free-living lifestyle to a surface adapted, structured lifestyle known as a biofilm. (southampton.ac.uk)
Microscopic analysis of cell and colony structure indicates that CmrRST promotes the formation of elongated bacteria arranged in bundled chains, which may contribute to bacterial migration on surfaces. (nih.gov)
The realization of the vastness of bacterial diversity and the development of novel experimental techniques have propelled molecular microbiology into a new era of investigation This course provides insights into how genes are organized and regulated in bacteria and in their viruses. (lu.se)
Sequence variations between different bacteria provide a unique identity, and the analysis of these sequence enables taxonomic placement. (folkhalsomyndigheten.se)

The organic amendments increased CO 2 emissions with increased bacterial and archaeal abundance in the Kabwe site, while no impacts were shown in the Lusaka site. (researchsquare.com)

Development of molecular properties and reaction centers: loss of charge, appearance of apolar structures, ability to insert into membranes. (elte.hu)
Knowledge of the three-dimensional structures of the carbo-hydrate molecules is indispensable for a full understanding of the molecular processes in which carbohydrates are involved, such as protein glycosylation or protein-carbohydrate interactions. (iucr.org)
Although the use of polycation to complex and purify DNA has been described in the literature, elution often requires a high ionic strength or pH levels not compatible with molecular analyses. (mdpi.com)
Here, we investigate annotated FabG homologs, finding a low-molecular weight 3-oxoacyl-ACP reductase, as the most likely FASII FabG candidate, and high-molecular weight 3-oxoacyl-ACP reductase (HMwFabG), showing differences in structure and coenzyme preference. (rcsb.org)
To date, this is the second bacterial high-molecular weight FabG structurally characterized, following FabG4 from Mycobacterium. (rcsb.org)
To illustrate the capabilities of CAVER 3.0, the tool was applied for the analysis of molecular dynamics simulation of the microbial enzyme haloalkane dehalogenase DhaA. (plos.org)
Obtained results clearly demonstrate that analysis of molecular dynamics simulation is essential for the estimation of pathway characteristics and elucidation of the structural basis of the tunnel gating. (plos.org)
Identification methods are conceptually easier to interpret than molecular phylogenetic analyses and are often preferred when the groups are well understood. (asm.org)
Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)
With the help of various forms of mass spectrometry, synchrotron radiation, protein production & labelling, and bioinformatics, our facilities provide the opportunity to study protein structure and dynamics, molecular probes and drug design. (lu.se)
The course comprises molecular biology of genes, proteins, multicomponent protein complexes, and other biomolecules that provide structure and perform the organism's functions. (lu.se)
The effect of genetic structure on molecular dating and tests for temporal signal. (cdc.gov)
Krithika Ravi successfully defended her PhD thesis entitled "Towards bacterial valorization of low molecular weight lignin" on November 28, 2019. (lu.se)

The latter includes work on important human viral, parasite and bacterial pathogens. (embl.org)
The isolation of bacterial pathogens resistant to the commonly prescribed antibiotics from pregnant women symptomatic and asymptomatic for UTI calls for early screening of all pregnant women for UTI during antenatal care service delivery. (who.int)

Biofilms are increasingly recognised as the predominant mode of bacterial growth including within medical, engineered, and environmental contexts. (southampton.ac.uk)
We discovered that exogenous nitric oxide can act as a signal for the dispersal of bacterial biofilms. (southampton.ac.uk)

Bacterial isolates were identified based on their colonial morphology, Gram staining and biochemical reactions. (ispub.com)
This study was aimed at determining the urinary bacterial isolates and their susceptibility to selected antibiotics among pregnant women attending antenatal clinics of selected Hospitals in Ilorin, Nigeria. (who.int)
For contact tracing or inquiries related to antibiotic resistance, whole genome sequencing (WGS) of bacterial isolates is offered. (folkhalsomyndigheten.se)

An increase in bacterial mutation rate can promote biofilm formation. (southampton.ac.uk)
Bacterial biofilm formation causes many diseases inside oral cavity: gingivitis, periodontal disease, and caries, so that the search for alternative methods for biofilm control are very important 6,28,30 . (bvsalud.org)

At both sites, temporal changes of soil carbon dioxide (CO 2 ) emissions, bacterial and archaeal community structures were monitored during crop growing season (126 days). (researchsquare.com)
Additionally, despite the complexity of the honeybee's bacterial community, all groups exhibited a straightforward archaeal community structure. (biorxiv.org)

In this study, we assessed CO 2 emissions, litter bag decomposition rates, bacterial and archaeal abundance, and taxonomic diversity under different organic amendments at two different experimental sites in Zambia. (researchsquare.com)
Using the Illumina HiSeq platform, we analyzed the composition and diversity of the culture-enriched gut bacterial community. (springeropen.com)
Our data suggested that medium supplemented with blood could increase the diversity of the bacterial community. (springeropen.com)
Conclusions: Bacterial GEs exhibit much larger diversity than fungal counterparts. (proteopedia.org)
Today, rRNA-based analysis remains a central method in microbiology, used not only to explore microbial diversity but also as a day-to-day method for bacterial identification. (asm.org)

By PICRUSt analysis, some metabolism-related functions and signal transduction functions of the rhizosphere bacterial community in the M. incognita infection-tobacco plants had a higher relative abundance than those uninfected. (ppjonline.org)
Our findings indicate that C. difficile employs phase variation of the CmrRST signal transduction system to generate phenotypic heterogeneity during infection, with concomitant effects on bacterial physiology and pathogenesis. (nih.gov)

PID can result from untreated bacterial infections, including chlamydia and gonorrhea, and can lead to infertility, ectopic pregnancy, and chronic pelvic pain ( 1 ). (cdc.gov)
Iclaprim, a diaminopyrimidine antimicrobial, was compared with vancomycin for treatment of patients with acute bacterial skin and skin-structure infections (ABSSSIs) in two studies (REVIVE-1 and REVIVE-2). (whiterose.ac.uk)
Urinary tract infections (UTIs) are the most prevalent bacterial infections in pregnancy. (ispub.com)
Urinary tract infections are the most prevalent bacterial infections during pregnancy [1] The burden of UTI disease is estimated at 150 million cases yearly worldwide, with various types of UTI causing significant health problems that affect millions of people [2]. (ispub.com)
However, nongonococcal bacterial infections can also occur and can rapidly destroy joint structures. (msdmanuals.com)

2023. Editorial: Role of Transcription Factors and Sigma Factors in Bacterial Stress. (openwetware.org)

PID occurs when microorganisms ascend from the vagina or cervix to the fallopian tubes and other upper genital tract structures ( 1 ). (cdc.gov)
To understand the processes by which the granules develop, this study focused on the altitudinal distribution of the granules and photosynthetic microorganisms on the glacier, bacterial community variation with granules size and environmental factors affecting the growth of the granules. (wattsupwiththat.com)
It can be caused by a large variety of microorganisms, but has essentially two distinct etiologies: bacterial and fungal. (who.int)
Bacterial biofilm can be simply defined as a set of microorganisms and their extracellular products, adhered on many surface types. (bvsalud.org)

CAVER is a software tool widely used for the identification and characterization of transport pathways in static macromolecular structures. (plos.org)
In this study, we significantly expanded the existing knowledge on CE15 with the in-depth characterization of ten bacterial GEs broadly spanning the phylogenetic tree, and also presented two novel enzyme structures. (proteopedia.org)
These models provide a unique visualization window for the analysis of physical chemistry and the morphological characterization of microbial communities. (lu.se)

To explore the relationships between nonpathogenic organisms colonizing TIVAPs and the potential risk of infection, we analyzed the bacterial community parameters between TIVAPs suspected (symptomatic) or not (asymptomatic) of infection. (hal.science)
According to the findings, M. incognita infection can alter the bacterial population in the soil. (ppjonline.org)
Principal Coordinate Analysis revealed clear separations between bacterial communities from infested and uninfested soil, indicating that different infection conditions resulted in significantly different bacterial community structures in soils. (ppjonline.org)
The infection resides in synovial or periarticular tissues and is usually bacterial-in younger adults, frequently Neisseria gonorrhoeae . (msdmanuals.com)

5. Structure and function of Q-type centers in bacterial photosynthetic organisms. (elte.hu)

The creation and isolation of specific mutants is a cornerstone of bacterial genetics. (lu.se)

In an integrated analysis of the interactions between changes in the microbiota and host gene dysregulation, we found an agreement between the microbiota and transcriptomic responses to B. pettiboneaei parasitism. (frontiersin.org)
Microbiota oral contains bacterial spores. (medscape.com)

2022. Analysis of Carbohydrate-Active Enzymes and Sugar Transporters in Penicillium echinulatum: a Genome-wide Comparative Study of the Fungal Lignocellulolytic System. (openwetware.org)
The bacterial GEs were able to utilize substrates lacking 4-OH methyl substitutions, known to be important for fungal enzymes. (proteopedia.org)

The samples were incubated in bacterial suspension (S. mutans) enriched with 20% sucrose to promote biofilm growth on the surfaces. (bvsalud.org)

We sought to characterise the bacterial and fungal stool flora of preterm neonates and organism viability and evaluate any associations with NEC and sepsis. (bmj.com)
Methods Stools were analysed by PCR-DGGE for assessment of the total bacterial and fungal communities by analysis of 16S rRNA and 28S rRNA, respectively. (bmj.com)
In 65 samples (25 infants), the viable (RNA) bacterial and fungal communities were analysed. (bmj.com)

Comparison of the structures of the new protein with those recently reported for N-acetyl-L-ornithine transcarbamylase indicates that amino acid residue 90 (B. fragilis numbering) plays an important role in conferring substrate specificity for N-succinyl-L-ornithine versus N-acetyl-L-ornithine. (nih.gov)
Changes in urine chemistry with elevated levels of glucose and amino acid encourage bacterial growth [13]. (ispub.com)

Comparative genomics of DNA-binding transcription factors in archaeal and bacterial organisms. (openwetware.org)

Here, we used culture-dependent and 16S rRNA gene-based culture-independent approaches to identify differences in bacterial colonization of TIVAPs obtained from two French hospitals. (hal.science)
Bacterial community structures, based on 16S rRNA gene amplicon sequencing, were different between the smaller and larger granules. (wattsupwiththat.com)
This study used 16S rRNA gene sequencing and PICRUSt to assess bacterial community structure and function changes in rhizosphere soil from Meloidogyne incognita -infected tobacco plants. (ppjonline.org)

Information on age, gestational age, gravidity, level of education and area of residence were recorded in a well-structured questionnaire. (ispub.com)
Socio-demographic, clinical, and laboratory data were collected using structured questionnaire. (bvsalud.org)

Construction and Analysis of Gene Co-Expression Network in the Pathogenic Fungus Ustilago maydis. (openwetware.org)
two protein structures were solved, and insights into their regulation and biological roles were gained through gene expression analysis and enzymatic assays on complex biomass. (proteopedia.org)
The gene expression analysis demonstrated that bacterial GE-encoding genes were differentially expressed as response to different carbon sources. (proteopedia.org)

We also observed larger temporal variability in soil microbial community structure in Kabwe than in Lusaka. (researchsquare.com)
I developed artificial porous media that mimic oil reservoirs, soil structures, and cement concrete pore networks. (lu.se)
As a crucial member of the Soil Chip team led by Edith Hammer, I take on the responsibility of designing and fabricating microfluidic devices, leveraging deep learning techniques to analyze soil bacterial communities efficiently. (lu.se)

Interactions of antimicrobial dressings with bacterial load, biofilm matrix and the overall protein-rich wound microenvironment remain insufficiently studied. (lohmann-rauscher.com)
This analysis aimed to extend the investigation on the efficacy of a variety of antimicrobial dressings using an in vitro biofilm model (lhBIOM) mimicking the specific biofilm-environment in human wounds. (lohmann-rauscher.com)
5 evaluated the antimicrobial activity of a resin composite containing silver nanoparticles, at two concentrations, and verified that the amount of adhered bacterial cells was smaller. (bvsalud.org)

The purpose of these analyses was to assess the burden of self-reported PID in a nationally representative sample using data from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 cycle. (cdc.gov)
This work utilized amplicon sequencing of the bacterial and archaeal 16S rRNA genes to assess the bacterial and archaeal communities of adult bee groups (healthy and affected by Varroa designed in NG and VG, respectively) and larvae from Varroa destructor -infected hives. (biorxiv.org)

Then, we calculated the numbers of bacterial colonies and collected the bacterial culture mixtures from each kind of medium. (springeropen.com)

HU is a small (10 kDa) bacterial DNA-binding protein, which structurally differs from a eukaryotic histone but functionally acts similarly to a histone by inducing negative supercoiling into circular DNA with the assistance of topoisomerase. (wikipedia.org)

The spearman correlation analysis revealed that UPF supplementation reduced the relative abundance of Parasutterella and possibly decreased the blood sugar levels, leading to a decrease in the relative abundances of Blautia and Fusicatenibacter and a subsequent decrease in insulin levels. (frontiersin.org)
Multivariate analysis suggests that the abundance of mineral particles on the glacier surface is the main factor controlling growth of these cyanobacteria. (wattsupwiththat.com)

Despite containing residues for catalysis and the ACP coordinating motif, biochemical analyses showed limited activity against an acetoacetyl-CoA substrate in vitro. (rcsb.org)
Biochemical and structural features of diverse bacterial glucuronoyl esterases facilitating recalcitrant biomass conversion. (proteopedia.org)
Arnling Baath J, Mazurkewich S, Knudsen RM, Poulsen JN, Olsson L, Lo Leggio L, Larsbrink J. Biochemical and structural features of diverse bacterial glucuronoyl esterases facilitating recalcitrant biomass conversion. (proteopedia.org)

bacterial etiology, pregnant women, susceptibility profile. (ispub.com)

EMBL Grenoble also operates the High Throughput Crystallization Facility (HTX lab), which integrates protein crystallisation into efficient structure determination pipelines. (embl.org)
Their focus is creating pipelines to enhance and automate analyses. (folkhalsomyndigheten.se)
Pipelines are series-connected data processes that utilise software tools to structure, process, and interpret genetic information. (folkhalsomyndigheten.se)

Scientists at EMBL Grenoble determine 3D structures of human and viral proteins to understand how they interact with the nucleic acids DNA and RNA. (embl.org)

Antifungal prophylaxis was associated with altered bacterial community and a reduction in bacterial richness was observed in week 4, correlating with high antibiotic exposure. (bmj.com)

Quantitative analysis was performed using a quantitative suspension method, separately assessing remaining microbial counts within the solid biofilm as well as the dressing eluate (representing the absorbed wound exudate). (lohmann-rauscher.com)

Macromolecular synthesis (chromosome structure, cell division and its control). (lu.se)

The Ribosomal Database Project (RDP) Classifier, a naïve Bayesian classifier, can rapidly and accurately classify bacterial 16S rRNA sequences into the new higher-order taxonomy proposed in Bergey's Taxonomic Outline of the Prokaryotes (2nd ed., release 5.0, Springer-Verlag, New York, NY, 2004). (asm.org)

As a result, rhizosphere soils from tobacco plants infected with M. incognita showed considerable bacterial community structure and function alterations. (ppjonline.org)

We studied the rhizosphere bacterial community structure of M. incognita -infected and uninfected tobacco plants through a paired comparison design in two regions of tobacco planting area, Yuxi and Jiuxiang of Yunnan Province, southwest China. (ppjonline.org)
Significant drivers of community structure differed based on either total or viable analysis. (bmj.com)

Because eukaryotic BATs are recalcitrant to crystallographic analysis, our understanding of the mechanism of these inhibitors and antidepressants is limited. (rcsb.org)

Recent highlights include: the structure and function of long non-coding RNAs , the structure of the integrator complex , the determination of the mechanism of action of secreted Legionella effector proteins , and the structural and mechanistic analysis of the transcription/replication machines of influenza virus and lassa virus . (embl.org)

The 3D structure of a biological molecule can tell you a lot about what that molecule does - and how its biological activity might be blocked or altered, for example to treat a disease. (embl.org)
In this letter, we present a very convenient and efficient technique of direct replication of biological structures via a two-step phase-separation micromolding process (PSμM). (acs.org)

Antibiotic resistance is a huge problem in both medicine and agriculture, and continuing searches for new antibiotics are very important as they may provide leads for future anti-bacterial agents. (rutgers.edu)

Furthermore, transcriptomic analysis of the liver tissues displayed that the peroxisome proliferator activated receptor-1α (PPAR) and AMP-activated protein kinase (AMPK) signaling pathway genes ( Pparaa, Cpt1a, Prkaa1, Prkab1, Prkaa2 , and Ppargc1a ) were upregulated in those groups supplemented with UPF. (frontiersin.org)

In the crystal structure, the mol-ecules are connected into chains running in the b -axis direction by O-H⋯N hydrogen bonding. (iucr.org)
Furthermore the mol-ecular and crystal structure of the title compound, 2 , are presented together with a Hirshfeld surface analysis and non-covalent inter-action plots. (iucr.org)
Crystal structure of photosystem II. (elte.hu)
Crystal structure of photosystem I. Structure and function of FeS-type centers of Chlorobium and Heliobacteria, comparison with photosystem I. FeS-type centers containing chlorophyll d. (elte.hu)
CAVER 3.0 safely identified and reliably estimated the importance of all previously published DhaA tunnels, including the tunnels closed in DhaA crystal structures. (plos.org)
We determined 12 crystal structures of LeuBAT in complex with four classes of antidepressants. (rcsb.org)

In addition, beef powder and peptone could significantly change the culture-enriched bacterial community. (springeropen.com)
Total bacterial communities significantly differed between healthy infants and those with NEC or sepsis, with Sphingomonas spp. (bmj.com)

The aim of the present meta-analysis was to examine the possible association between insulin treatment and risk of fr. (researchgate.net)
Analyses were performed to examine the possible effects of demographic or treatment related factors and the development of NEC or sepsis. (bmj.com)

C-IOD demonstrated superior bacterial reduction. (lohmann-rauscher.com)

We will be able to determine the direction of carbon flow by establishing which compounds are labelled first and because bacterial and archaeal lipids are readily distinguished on the basis of their chemical structures and because some preliminary analyses of the lipid contents. (europa.eu)
Chemical structure of isoeugenol. (researchgate.net)
Characteristics of individual transport pathways, including their geometry, physico-chemical properties and dynamics are instrumental for understanding of structure-function relationships of these proteins, for the design of new inhibitors and construction of improved biocatalysts. (plos.org)

Furthermore, they often overlooked the functional characteristics of bacterial community in silage. (springeropen.com)

The HTX Facility also promotes structure-guided drug design, through automated facilities for ligand and fragment screening. (embl.org)

Here, we show that by using fractal mathematics analysis alone, one can readily quantify the degree of entropy difference (and thus, their structural complexity) of living processes (lichen growths and plant growing patterns in this case) as distinct entities separate from its similar abiotic surroundings. (cambridge.org)
The four institutes join forces in the Partnership for Structural Biology (PSB), which provides a uniquely comprehensive range of state-of-the-art structural biology platforms for sample production, sample characterisation and structure determination for both in house research and external users. (embl.org)

Structure, function and regulation of PEP carboxylase. (elte.hu)

The bacterial type II fatty acid synthesis (FASII) pathway is an attractive target for the development of inhibitors and is particularly favourable due to the differences from mammalian type I fatty acid synthesis. (rcsb.org)

The two solved structures revealed similar overall folds to known structures, but also indicated active site regions allowing for more promiscuous substrate specificities. (proteopedia.org)

Binding proteins6

Species10

Bacteria10

Increased bacterial and archaeal1

Molecular13

Pathogens2

Biofilms2

Isolates3

Biofilm formation2

Archaeal community2

Diversity5

Signal transduction2

Infections5

20231

Microorganisms4

Characterization3

Infection4

Photosynthetic1

Genetics1

Microbiota2

Enzymes2

Promote biofilm1

Fungal3

Amino Acid2

Genomics1

RRNA gene3

Questionnaire2

Gene3

Soil3

Antimicrobial3

Assess2

Colonies1

Structurally1

Abundance2

Biochemical3

Susceptibility1

Pipelines3

Viral1

Richness1

Microbial1

Macromolecular1

Rapidly1

Soils1

Community structure2

Recalcitrant1

Transcription1

Biological2

Antibiotic resistance1

Genes1

Crystal6

Significantly2

Examine the possible2

Reduction1

Chemical3

Functional characteristics1

Promotes1

Structural2

Regulation1

Differences1

Substrate1