• Designing and modeling such processes requires a strong fundamental understanding of the chemical and biological phenomena at work. (sdsmt.edu)
  • Both behaviors are instrumental in biological function and enzymatic processes in general. (purdue.edu)
  • Gene ontology functional enrichment analysis revealed twenty eight biological processes and 10 molecular functions associated with cognitive impairment. (ijpsonline.com)
  • Studies published in In Silico Biology generally use theoretical models and computational analysis to gain quantitative insights into regulatory processes and networks, cell physiology and morphology, tissue dynamics and organ systems. (iospress.com)
  • Genes determined to have altered expression levels in schizophrenics relative to controls are involved in a number of biological processes, including synaptic plasticity, neuronal development, neurotransmission, and signal transduction. (mssm.edu)
  • Keren Yizhak majored in computational biology at the Hebrew University of Jerusalem and is currently a PhD student at the School of Computer Science at Tel-Aviv University, where she uses computational techniques to study biological phenomena, focusing on the metabolic changes that occur in cells during cancer and ageing. (elifesciences.org)
  • Keren Yizhak uses computational techniques to study biological phenomena. (elifesciences.org)
  • I develop computational methods that help us to integrate large amounts of detailed biological data collected from cells with this model. (elifesciences.org)
  • Here, I will present some lines of work where computational modelling and analysis is used to study changes in neural tissue during brain development and degeneration. (surrey.ac.uk)
  • In Silico Biology is a scientific research journal for the advancement of computational models and simulations applied to complex biological phenomena. (iospress.com)
  • Experimental support may also be provided to support the computational analyses. (iospress.com)
  • We strive to provide computational frameworks for understanding how observable biological properties arise from complex systems. (iospress.com)
  • A secondary goal that should be sought by a bioinformatics facility is to make algorithms and analysis methods accessible for non-computational biologists. (lu.se)
  • A computational platform for high-throughput analysis of RNA sequences and modifications by mass spectrometry. (nih.gov)
  • In Systems Biology, mathematical modeling and computational software are important tools to unravel the complexity of biological systems and predict their behavior under different perturbations [ 1 ]. (biomedcentral.com)
  • Class examples and coursework apply general techniques to problems in biological signal analysis, including circuits, enzyme kinematics, and physiological system analysis. (illinois.edu)
  • EMRM 2023 is devoted to the mathematical analysis of PDE models for multi-component systems and reactive mixtures. (wias-berlin.de)
  • Use different mathematical tools to model physical and biomedical/biological phenomena and systems (i.e., differential equations, convolution, and signal transforms). (illinois.edu)
  • My main focus regards the interpretation of Feynman diagrams that could be considered as depiction representing physical phenomena as well as merely mathematical tools. (google.com)
  • The analysis of stability and stabilization in dynamical systems, spanning fields such as physical, biological, and engineering, allows for the exploration of complex phenomena. (amrita.edu)
  • In in 2003 and given to the wrong parents, The family returned to the hospital this case, relatives may claim the child a fact which was not discovered until 4 in Saudi Arabia to find their biological on the basis of physical resemblance. (who.int)
  • Currently, researchers have encountered low expression level in many fungi transgenic research, so it is of great practical significance and economical value to investigate the application of codon bias analysis in foreign gene expression in fungi. (novapublishers.com)
  • In this review, we summarize the basic theories and analysis methods about codon bias, and introduce the application of codon bias analysis in foreign gene expression in three categories of fungi - yeasts, molds and mushrooms respectively. (novapublishers.com)
  • The biological insight gained from Horizon's single cell RNAseq-linked CRISPR screening platform could help researchers to gain further understanding into complex biological models and speed up the time from discovery to validation by integrating the effect of gene editing with complex gene expression mapping. (biospace.com)
  • Analysis of massive gene expression data requires statistical methods, data mining approaches, and data base storage and searches tools, but most relevant is the standardization of experimental protocols, data format, information describing experimentals, and other experimental and analytical aspects, to be able to exploit data sets from different laboratories in large scale analysis of data. (nettab.org)
  • 3 ] used large-scale experimental data from the SEQC (Sequencing Quality Control) consortium, consisting of replicates of well-known cell lines, to evaluate the performance of differential gene expression methods and the effects of modifying sequencing depths and the number of biological replicates. (biomedcentral.com)
  • To identify molecular substrates associated with schizophrenia, DNA microarray analysis was used to assay gene expression levels in postmortem dorsolateral prefrontal cortex of schizophrenic and control patients. (mssm.edu)
  • They're based on the analysis of DNA methylation, a biological process by which CH3 methyl groups are added to the DNA molecule and that determines gene expression. (medscape.com)
  • In the meantime, bioinformatics is solicited to create the tools of analysis and interpretation to understand the biological phenomena under investigation. (nettab.org)
  • Ability to deploy across high performance computing systems sophisticated mathematical modeling frameworks, data analysis pipelines and bioinformatics workflows to address complex biological phenomena. (vliz.be)
  • The Protein Structure and Bioinformatics (LU PSB) develops methods and performs analyses to understand biological and medical phenomena at genetic, functional, mechanical and systems level. (lu.se)
  • I believe that developing new and creative ways for analyzing and modelling the enormous amounts of biological data that are being generated is of great importance. (elifesciences.org)
  • His pioneering work on using system analysis and computer modelling techniques to quantify and predict biological phenomena, and conduct risk assessments, is still having impact today in the USA and Asian rice growing countries. (rsis.edu.sg)
  • Further, the relationship between measurement and modelling is introduced as a way to describe spatial and temporal phenomena. (lu.se)
  • ChE graduates are recruited for their technical engineering knowledge as well as their problem solving, systems analysis, and communication skills. (sdsmt.edu)
  • and biochemistry and biotechnology with a focus on evolutionary systems biology (Ghent University, PhD.). More than 9 years of expertise in developing and applying systems biology-oriented mathematical modeling, evolutionary algorithms and combinatorial optimization methods, multimodal data analysis and visualization methods. (vliz.be)
  • We publish peer-reviewed leading-edge biological, biomedical and biotechnological research in which computer-based (i.e., 'in silico' ) modeling and analysis tools are developed and utilized to predict and elucidate dynamics of biological systems, their design and control, and their evolution. (iospress.com)
  • Today, ISB is dedicated exclusively to biological systems modeling and multi-scale simulations and is published solely by IOS Press. (iospress.com)
  • Apply linear systems methods (i.e., convolution, Fourier analysis, and Laplace analysis) to characterize these models and calculate analytical solutions. (illinois.edu)
  • In cancer systems biology, biological networks are typically modeled through Ordinary Differential Equation (ODE) models. (biomedcentral.com)
  • It offers the users the ability to import a mathematical model in Systems Biology Markup Language (SBML), to perturb the model parameter space and to choose the reference node for the robustness analysis. (biomedcentral.com)
  • The other research line in highly related and investigates the effects of the variations and perturbations as systems biological and medical level. (lu.se)
  • The socioeconomic gradient in and biological systems. (who.int)
  • In this paper, the transport phenomena of synaptic electric impulses are considered. (mdpi.com)
  • The only feasible approach to large molecule calculation at the time was to use lattice methods which Prof. Prohofsky used regularly in vibrational mode analysis in crystalline solids. (purdue.edu)
  • Several reports have recently provided snapshots of the performance of gene-level differential expression analysis methods, using both synthetic and experimental data [ 1 - 5 ]. (biomedcentral.com)
  • We use a combination of methods to map, via quantitative content analysis of CRISPR papers, the research funding profile of major government agencies and philanthropic organizations and the networks involved in supporting key stages of high-influence research, namely, basic biological research and technological development. (mit.edu)
  • METHODS: We conducted a secondary analysis of data from the Child Health Epidemiology Reference Group, including 11 population-based pregnancy or birth cohort studies, to evaluate the appropriateness of vital event data for mortality estimation. (bvsalud.org)
  • OSH studies regardless of focus should incorporate inclusive methods for recruitment, data collection, and analysis to reflect societal diversity and account for differing experiences of social conditions. (cdc.gov)
  • RNA-seq has been a boon to the quantitative analysis of transcriptomes. (biomedcentral.com)
  • From an analysis perspective, there are several ways to approach RNA-seq data to unravel differential transcript usage, such as annotation-based exon-level counting, differential analysis of the percentage spliced in, or quantitative analysis of assembled transcripts. (biomedcentral.com)
  • Gene ontology functional enrichment analysis was performed using search tool for the retrieval of interacting genes/proteins. (ijpsonline.com)
  • Summary: A generalized goal of many high-throughput data studies is to identify functional mecha-nisms that underlie observed biological phenomena, whether disease outcomes or metabolic out-put. (pnnl.gov)
  • However, the total gene count derived from Roary analysis exhibited a perplexing range, fluctuating from 250,000 to 470,000 genes. (biostars.org)
  • The ability to predict changes in shape based on vibrational mode analysis was demonstrated very early on in the program. (purdue.edu)
  • We have been able to cover some interesting cases by the mathematical analysis thanks to a fruitful analogy with some SIR type model. (europa.eu)
  • On the side of mathematics, in 2022 I began working on several topics in mathematical analysis. (google.com)
  • Typically, in unraveling interesting biological phenomena, inferring changes in expression is a critical, yet initial step of the discovery pipeline, and the results often feed into downstream interpretive analyses. (biomedcentral.com)
  • Docking studies were carried out with AutoDock4.2v. Molecular dynamics analyses were performed using Schrodinger Desmond 6.1v software for a 50 ns production run. (ijpsonline.com)
  • Bifurcation analysis is performed to identify stability properties of the model's steady state, and numerical simulations are performed to illustrated different types of dynamics associated with the cycle. (surrey.ac.uk)
  • The results of the content analysis show how the research supported by the main U.S. government agencies focuses both on the study of CRISPR as a biological phenomenon and on its technological development and use as a biomedical research tool. (mit.edu)
  • My colleague Mattia Sensi and I have generalized some results concerning the models quoted above, by using classical tools of differential geometry and analysis. (google.com)
  • Moreover, applications of such models arise in several biophysical phenomena in different fields such as, for instance, biology, medicine and electronics, where, by means of nanoscale memristor networks, scientists seek to reproduce the behavior of biological synapses. (mdpi.com)
  • Given all the variables and the noisy nature of biology, the fact that we still manage to identify targets that have a true biological meaning is always very exciting and rewarding. (elifesciences.org)
  • With the right analyses we can potentially shed light on many biological phenomena that could not have otherwise been revealed. (elifesciences.org)
  • Should I consider employing an alternative program for Pangenome analysis to potentially rectify these unexpected outcomes? (biostars.org)
  • Provide an analysis of the extent to which addiction to psychoactive drugs is a biological versus a psychological phenomenon. (submityouressays.com)
  • A biopsychosocial approach explores the dynamic, multidirectional interactions between biological phenomena, psychological factors, and social contexts, and can be a tool for both deeper understanding of the social determinants of health and advancing health equity. (cdc.gov)
  • The We analysed 16 gene regions iso- portant to preserve the marriage union, psychological and social dimensions lated from blood samples taken from a baby girl may be switched with a baby of the event have not been explored the mother, father and child. (who.int)
  • Assistant to the Secretary of Defense for Nuclear and Chemical and Biological Defense Programs, Washington, DC. (cdc.gov)
  • Hence, robustness analysis consists in quantifying how much the temporal behavior of a specific node is influenced by the perturbation of model parameters. (biomedcentral.com)
  • Dr. Szymanski's research interests span from network science, with emphasis on social networks and computer wireless and sensor networks to analysis and design of distributed algorithms, simulation of computers, networks and biological/ecological phenomena. (rpi.edu)
  • ChE students develop a wide range of problem solving skills grounded in mathematics and computer analysis techniques. (sdsmt.edu)
  • Currently, it can be challenging to adequately multiplex the data from these screens to evaluate complex biological phenomena occurring in a subset of edited cells. (biospace.com)
  • This resulted in analyses to evaluate and correct errors arising from such liquid junction potentials in a range of different situations and led him to develop a C/C++ DOS-based Windows software program, JPCalc , to calculate and apply appropriate corrections to experimental membrane potential measurements. (edu.au)
  • He is best known for his Threat Simulation Theory, which - in the tradition of evolutionary psychology - states that dreams serve the biological function of rehearsing possibly threatening situations in order to aid survival, and his advocacy of the dreaming brain as a model of consciousness. (wikipedia.org)
  • We shall continue to explore the new convexity structure unraveled by our analysis of the Fisher infinitesimal model. (europa.eu)
  • No one supposes that there is any connexion between horse-kicks suffered by soldiers in the German army and blood cells on a microscope slide other than that the same urn scheme provides a satisfactory abstract model of both phenomena. (upenn.edu)
  • The term 'in silico' is a pendant to 'in vivo' (in the living system) and 'in vitro' (in the test tube) biological experiments, and implies the gain of insights by computer-based simulations and model analyses. (iospress.com)
  • These software are designed to assist the users at different stages of the modeling process, from model generation to parameter estimation and model analysis. (biomedcentral.com)
  • The analysis of these results, in terms of a statistical-mechanical model that incorporates polymer flexibility as well as the excluded volume of the protein, shows that the dramatic enhancement of bovine pancreatic trypsin inhibitor self-association can be quantitatively rationalized in terms of hard repulsive interactions. (lu.se)
  • We are working in that direction, following new experimental set up, and new scientific challenges.More precisely, we aim at building a theoretical framework to describe propagation of biological waves, and patterns of adaptation of populations, either in a stationary or in a changing environment. (europa.eu)
  • We will emphasize experimental design, data collection in the field and in the laboratory, data analysis, and writing skills. (middlebury.edu)
  • Despite the predicted large magnitude of this universal effect and its far-reaching biological implications, few experimental studies of macromolecular crowding have been reported. (lu.se)
  • Whereas theoretical predictions of macromolec- use of nonadsorbing polymers, like polyethylene glycol, for ular crowding effects abound, there are remarkably few protein separation (Albertsson, 1986) and crystallization experimental studies of this universal phenomenon. (lu.se)
  • Analyses were descriptive, summarizing study designs, populations, protocols, and internal checks to assess their impact on data quality. (bvsalud.org)
  • Robustness is defined as the ability of a biological system to maintain its functionalities against internal and external perturbations [ 4 ]. (biomedcentral.com)
  • Ascarelli, Prohofsky, and Van Zandt collaborated for several years forming a molecular biological physics group that worked at improved models by strong correlation of theory and experiment. (purdue.edu)
  • Professor Earl Prohofsky spent the first decade of his professional career as a theoretical physicist doing analysis on second sound in super fluid helium and crystalline solids, thermal conductivity, ultrasonic attenuation and electron-vibration wave interaction. (purdue.edu)
  • Exercises in usage of computer based analysis and presentation tools, information retrieval and oral and written presentation techniques are included in certain learning activities. (lu.se)
  • The unification of all biological databases would be hugely beneficial. (elifesciences.org)
  • We have designed and analysed Asymptotic-Preserving schemes for some quantitative genetics models with a linear operator for the distribution of the effects of mutations, in the regime of vanishing variance. (europa.eu)
  • asymptotic analysis. (wias-berlin.de)
  • Analysis of 2179 clonal sequences derived from hypervariable region 1 (HVR1) of the HCV genome in samples obtained from patients with acute (n = 49) and chronic (n = 102) HCV infection showed that intra-host HVR1 diversity was 1.8 times higher in patients with chronic than acute infection. (iospress.com)
  • His work seeks to understand consciousness as a biological phenomenon. (wikipedia.org)
  • I am not sure I understand why you think there is a problem with your analysis. (biostars.org)
  • According to a 2017 study in Sleep, an analysis of the statistical content of intelligible sleep-talking found that 24 percent contained negative content, 22 percent had "nasty" language, about 10 percent contained a variation of the word "no", and 10 percent contained profanity. (wikipedia.org)
  • With its unique set of functions, the CRA Toolbox is a remarkable software for the topological study of biological networks. (biomedcentral.com)
  • In 1973 he became interested in the question of whether vibrational waves could be important in the description and analysis of biological phenomena. (purdue.edu)
  • Horizon's pooled format screens offer researchers access to highly robust whole-genome level analyses that yield quality data outputs. (biospace.com)
  • One of the key analysis challenges with RNA-seq data is to infer a set of such units that change their expression level or expression pattern between conditions. (biomedcentral.com)
  • In general, there is substantial literature on worker hazards related to ambient temperatures, biological hazards, and extreme weather but less on air pollution, ultraviolet radiation, industrial transitions, and the built environment. (cdc.gov)
  • Learn about current research in biological physics . (purdue.edu)
  • I am currently engrossed in the analysis of gram-positive pathogenic bacterial genomes, having meticulously selected approximately 300 genomes for my research. (biostars.org)
  • Such research must demonstrate application to a concrete biological problem. (iospress.com)
  • Given that Roary is widely recommended in the literature for bacterial Pangenome analysis, are there specific adjustments or configurations within the Roary program that I could explore to align with my expectations? (biostars.org)
  • Section 3 addresses legal and structural features relevant to the analysis that follows, including regarding a potential new instrument for pandemic preparedness and response and adjustments to the IHR. (who.int)
  • Section 4 analyses the value of and incentives for (that is, broadly, the benefits of) making adjustments to the IHR to further address pandemic preparedness and response, and related risks. (who.int)
  • This target could not have been found by conventional data analysis. (elifesciences.org)
  • Interview audio was transcribed, and rapid qualitative data analysis was used to analyze transcripts. (cdc.gov)
  • To analyse the time-series 3D microscopic images of developing embryos with fluorescently labelled nuclei, these studies used image segmentation. (nature.com)
  • To support mathematical modeling of biological networks, the use of software tools has grown substantially in recent years. (biomedcentral.com)
  • social and biological phenomena. (who.int)
  • It defines the dichotomy whereby and risk factors with biological mea- sociation between the overall social individuals actively determine the surements (Vineis et al. (who.int)
  • Group theory analysis shows that this displacement is also an eigenvector of a vibrational mode whose eigenfrequency approaches zero. (purdue.edu)
  • An ever- ``horses for courses'' approach whereby existing increasing number of unique nanomaterials are cre- analytical tools (such as risk ranking, multi-criteria ated every year, each engineered to take advantage of decision analysis, and ``control banding'' approaches) the properties that emerge when materials are manip- might be adapted to regulators' goals in particular ulated at the nanoscale (Maynard 2007 ). (cdc.gov)