Amylase secretion. Medical search. Frequent questions

Autonomic dysfunction in patients with irritable bowel syndrome evidenced by alterations of salivary alpha-amylase secretion. (nel.edu)
He L, Xie M, Zhang H, Meng L, Zhang X. Autonomic dysfunction in patients with irritable bowel syndrome evidenced by alterations of salivary alpha-amylase secretion. (nel.edu)
The PHF is screened for the phytochemical screening, and then the antidiabetic activity is determined by alpha-amylase inhibition. (hindawi.com)
In in vitro study, the result revealed polyherbal formulation in which hot water extract has the topmost inhibitory effect on alpha-amylase activity, ranging from 20.4% to 79.5% with an IC50 value of 48.98 ± 0.31 μ g/ml. (hindawi.com)
Studies on the alpha-amylase production were carried out with a bacterial strain isolated from a soil sample. (scielo.br)
The addition of calcium (10 mM) or peptone (1%) and yeast extract (0.5%) to the mineral medium shortened the lag period and improved the growth and alpha-amylase synthesis. (scielo.br)
The addition of glucose to the culture diminished greatly the synthesis of alpha-amylase, demonstrating that a classical glucose effect is operative in this organism. (scielo.br)
The addition of glucose to the culture diminished greatly the synthesis of alpha-amylase. (scielo.br)
02/2010 - 04/2011: Site-directed mutagenesis of alpha-amylase and characterization of biochemical (kinetic and activation) parameters of mutants and wild type. (uni-goettingen.de)
Here, the effects of these alkaloids on cell survival, the activity of superoxide dismutase, catalase, and glutathione peroxidase, factors associated with oxidative stress such as malondialdehyde and dityrosine, carbohydrate-hydrolyzing enzymes alpha-amylase and alpha-glucosidase, insulin secretion levels and glucose uptake ability were investigated. (ijpsonline.com)
Similar inhibition properties were shown by alpha-amylase and α-glucosidase and consequently, the investigated alkaloids could exhibit the high hypoglycemic effect. (ijpsonline.com)
Alpha amylase is of salivary or pancreatic origin and referred to as S-type or P-type amylase, respectively. (medscape.com)
Koh D, Ng V, Naing L. Alpha amylase as a salivary biomarker of acute stress of venepuncture from periodic medical examinations. (medscape.com)

Elevated amylase and/or lipase levels greater than three times the upper limit of normal in an appropriate clinical setting are suggestive of pancreatitis. (springer.com)
Pancreatitis can occur with normal or mild degree of amylase and lipase elevations, and thus, cross-sectional imaging can be helpful. (springer.com)
Severity of disease does not correlate with the degree of elevations of amylase and/or lipase. (springer.com)
Frank B, Gottlieb K. Amylase normal, lipase elevated: is it pancreatitis? (springer.com)
Evaluation of amylase and lipase in the diagnosis of acute pancreatitis. (springer.com)
Karsenti D, Bacq Y, Brechot J, Mariotte N, Vol S, Tichet J. Serum amylase and lipase activities in normal pregnancy: a prospective case-control study. (springer.com)
Lankisch PG, Burchard-Reckert S, Lehnick D. Underestimation of acute pancreatitis: patients with only a small increase in amylase/lipase levels can also have or develop severe acute pancreatitis. (springer.com)
Rats given piperine, the active principle of black pepper, showed an improved secretion of amylase, lipase and trypsin from the pancreas. (livestrong.com)
Pancreatin is a mixture of lipase (a fat-dissolving enzyme), protease (a protein enzyme), and amylase (an enzyme that aids in the digestion of starchy carbohydrates, and is often prescribed to people whose pancreatic secretions are low. (allstarhealth.com)
Pancreatin is composed of amylase, lipase, and protease. (taoofherbs.com)
A pancreatic pseudocyst is a collection of amylase-rich, lipase-rich, and enterokinase-rich fluid. (medscape.com)

It also blocks the inhibitory effects of serotonin on glucose-mediated insulin secretion [ 15 ]. (hindawi.com)
The pancreas plays a central role in both digestion and regulating metabolism through the production and secretion of insulin, along with other hormone-like molecules. (trivita.com)
Furthermore, glucose uptake and insulin secretion were enhanced by these compounds. (ijpsonline.com)
Anti-diabetic properties were evaluated by measuring the activity of carbohydrate digesting enzymes, glucose uptake into 3 T3-L1 adipocytes, and insulin secretion. (biomedcentral.com)
Basal and glucose-induced insulin secretion was measured in Min6 cells and found to be enhanced as well. (biomedcentral.com)

In summary, the maternal pancreas responded to nutrient restriction by decreasing pancreatic weight and activity of digestive enzymes while melatonin supplementation increased α -amylase content. (cambridge.org)
Intracellular signaling mechanisms activated by cholecystokinin-regulating synthesis and secretion of digestive enzymes in pancreatic acinar cells. (springer.com)
Recent discoveries of starch degrading enzymes have led to increased application of amylases in various industrial processes (1). (scielo.br)
Recent research with thermostable a-amylases has concentrated on the enzymes of thermophiles and extreme thermophiles (2,3,7,8,16,17,20) and little is known about the properties of the enzymes produced by these organisms. (scielo.br)
The pancreatic fluids secreted into the intestines contain three different types of digestive enzymes-proteases, lipases and amylases. (trivita.com)
Amylase enzymes change starch into sugars. (labpedia.net)
Secretion of pancreatic enzymes was increased by SH (trypsin) and casein (α-amylase, trypsin, and chymotrypsin) but not when SH + casein were infused together. (uky.edu)
Amylases are enzymes that catalyze the hydrolysis of amylopectin, amylose, glycogen, and their hydrolyzed products into simple and easily digestible sugars. (medscape.com)
The pancreatic enzyme amylase and brush border enzymes on microvilli lyse carbohydrates and disaccharides into constituent monosaccharides. (msdmanuals.com)
Gastric pepsin initiates digestion of proteins in the stomach (and also stimulates release of cholecystokinin that is critical to the secretion of pancreatic enzymes). (msdmanuals.com)

Nutrient restriction decreased ( P ⩽0.001) maternal pancreatic mass (g) and α -amylase activity (U/g, kU/pancreas, U/kg BW). (cambridge.org)
Ewes supplemented with melatonin had increased pancreatic mass ( P =0.03) and α -amylase content (kU/pancreas and U/kg BW). (cambridge.org)
Among healthy individuals, the pancreas and the salivary glands account for almost all the serum amylase, 40%-45% from the pancreas and 55%-60% from the salivary glands. (medscape.com)
The pancreas and salivary glands contain amylase concentrations that are several orders of magnitude greater than other organs. (medscape.com)
Electrophoresis shows that serum amylase is of two main types, as follows: (1) P-type amylase from the pancreas, and (2) S-type amylase from the salivary glands. (medscape.com)
The partly digested food leaves the stomach and enters the duodenum where it encounters secretions of the gall bladder and the pancreas. (curezone.org)
When the pancreas and salivary glands are inflamed, much more enzyme enters the blood, and as a result, more amylase is excreted in the urine. (labpedia.net)
Pancreatin production and secretion by the pancreas is essential to digestion and absorption of numerous nutrients, especially fats. (taoofherbs.com)
Amylase is an enzyme produced in the pancreas and by the salivary glands that converts starches, glycogens, and related polysaccharides into simple and easily digested sugar. (medscape.com)
Pancreatic amylase is secreted by acinar cells of the pancreas and is tissue specific and more temperature labile than salivary amylase. (medscape.com)

Coy DH, Mungan Z, Rossowski WJ, Cheng BL, Lin JT, Mrozinski JE, Jensen RT: Development of a potent bombesin receptor antagonist with prolonged in vivo inhibitory activity on bombesin-stimulated amylase and protein release in the rat. (wikipedia.org)
In exocrine acinar cells regulation of intracellular calcium plays a pivotal role in controlling fluid and protein secretion. (rochester.edu)
Amylase and total protein content were measured in saliva samples. (eur.nl)
RGTA-OTR4120 did not influence amylase or total protein secretion. (eur.nl)
Here, we increased the secretion of a heterologous α-amylase, a model protein used for studying the protein secretory pathway in yeast, by moderately overexpressing SEC16, which is involved in protein translocation from the endoplasmic reticulum to the Golgi apparatus. (dtu.dk)
PanaKare Plus is used as a digestive aid in replacement therapy where digestion of protein, carbohydrate and fat is inadequate due to deficient exocrine pancreatic secretions. (valleyvet.com)
Key to our ability to increase recombinant protein production through secretion is a better understanding of the pathways that interact to translate, process and export mature proteins to the surrounding environment, including the supporting cellular machinery that supplies necessary energy and building blocks. (mysciencework.com)
Pancreatic juice (67 mL/h) and protein (1.8 g/h) secretion rates were not affected by nutrient infusion. (uky.edu)
The effectiveness of the isolated high-copy-number plasmid for the overproduction of recombinant proteins was successfully demonstrated with two protein models Glutathione-S-transferase (GST) and α-amylase. (biomedcentral.com)
The proteins synthesized by parotid acinar cells are stored in large secretory granules whose composition includes α-amylase, leucine-rich parotid secretory protein (PSP), and proline-rich proteins (PRPs), in addition to multiple minor components 2-3 related to digestive and protective functions. (bvsalud.org)

American College of Gastroenterology American Gastroenterology Association International Association of Surgeons, Gastroenterologist and Oncologist European Crohn's and Colitis Organization Turkish Gastroenterology Association (Türk Gastroenteroloji Derneği) Türk Tıp Derneği Karaciğer Araştırmaları Derneği Gastrointestinal Motilite Derneği Mungan Z, Ertan A, Hammer RA, Arimura A: Effect of pituitary adenylate cyclase activating polypeptide on rat pancreatic exocrine secretion. (wikipedia.org)
Eight Angus steers (290 ± 8 kg), surgically prepared with pancreatic pouch-duodenal reentrant cannulas and abomasal infusion catheters were used in a replicated 4 x 4 Latin square experiment to investigate the effects of abomasal infusion of starch hydrolyzate (SH) and/or casein on pancreatic exocrine secretion and plasma concentration of hormones. (uky.edu)
These data indicate that positive effects of postruminal casein on enzyme secretion were inhibited by SH, emphasizing the complexity of the regulatory mechanisms involved in dietary adaptation of pancreatic exocrine secretion. (uky.edu)
Salivary seromucous glands are regulated predominantly by parasympathetic activation of muscarinic receptors, resulting in exocrine secretion of mucins and macroglobulin responsible by lubrication and protection of oral mucosa 3-4 . (bvsalud.org)

Amylase activity in the serum and urine is of pancreatic and salivary glands origin. (labpedia.net)
Saliva containing mucus and the enzyme amylase is secreted from 3 pairs of salivary glands, located in the head. (biologyonline.com)

Structure-dependent effect on pancreatic amylase secretion and jejunal strip contraction. (wikipedia.org)

Hyperamylasemia is most commonly the result of (1) pancreatitis or parotitis , (2) decreased metabolic clearance of amylase, or (3) amylase released from an involved organ. (medscape.com)
In acute pancreatitis, there is increased clearance of amylase in the urine compared to creatinine. (labpedia.net)

Typically, acute fluid collections do not have high amylase concentrations. (medscape.com)
These features are in contrast to those of pancreatic pseudocysts, which have high amylase concentrations, are surrounded by a thick, fibrous capsule, and are oval or round. (medscape.com)

In a study published in 'Die Nahrung' in 2000, researchers from the Central Food Technological Research Institute in India wanted to explore the effect of dietary spices on enzyme secretion. (livestrong.com)
Changes in hormone concentration may not relate directly to changes in enzyme secretion. (uky.edu)

Lipases break down fats into fatty acids and amylase breaks down starch into sugars. (trivita.com)

Mungan Z, Ozmen V, Ertan A, Coy DH, Baylor LM, Rice JC, Rossowski WJ: Structural requirements for galanin inhibition of pentagastrin-stimulated gastric acid secretion in conscious rats: Effect of potent novel rat galanin agonist. (wikipedia.org)
From these results, we make the hypothesis that in CS rats, CCK increased pancreatic secretion, which may favor a quicker absorption of carbohydrates and consequently induces an enhanced inhibition of lipid oxidation in the liver, leading to a progressive accumulation of fat preferentially in visceral deposits. (frontiersin.org)

Mungan Z, Ozmen V, Ertan A, Arimura A: Pituitary adenylate cyclase activating polypeptide-27 (PACAP-27) inhibits pentagastrin-stimulated gastric acid secretion in conscious rats. (wikipedia.org)
Rossowski WJ, Zacharia S, Mungan Z, Ozmen V, Ertan A, Baylor LM, Jiang NY, Coy DH:Reduced gastric acid inhibitory effect of a pGIP(1-30) NH2 fragment with potent pancreatic amylase inhibitory activity. (wikipedia.org)
Research [1] shows that coffee consumption does change the composition of the gut microbiota and stimulates gastric, biliary, and pancreatic secretion. (nchc.org)
In a study published in 'The African Journal of Medicine and Medical Sciences' in 2002, researchers from the University of Port Harcourt investigated the effects of piperine on gastric acid secretion in rats. (livestrong.com)
Piperine had a significant effect on gastric acid, increasing levels of secretion by up to 22 percent. (livestrong.com)

In acute pancreatitis, serum amylase is usually elevated 3-fold and then returns to normal by 3-7 days. (medscape.com)
Urinary amylase clearance is increased in acute pancreatitis from normal to 3 folds. (labpedia.net)
Urine amylase may remain elevated up to 2 weeks after the acute episode of acute pancreatitis. (labpedia.net)
Serum amylase increases in 6-48 hrs of onset of acute pancreatitis but not in proportion to the severity of the disease and activity returns to normal in 3-5 days. (medscape.com)

The first chemical breakdown of food also occurs in the mouth thanks to salivary amylase, an enzyme that begins breaking down carbohydrates. (trivita.com)

The 2 tests for amylase are serum and urine. (medscape.com)

Amylase from pancreatic acini goes through the pancreatic duct into the duodenum. (labpedia.net)

Fallopian tube secretions, tears, breast milk, and sweat have amylases with a similar electrophoretic mobility of salivary isoamylase. (medscape.com)

Pancreatin helps people with pancreatic disorders (cystic fibrosis, pancreatitis) whose pancreatic secretions are low to properly digest food. (allstarhealth.com)

The optimum temperature and initial medium pH for amylase synthesis by the organism were 50°C and 7.0 respectively. (scielo.br)

The exact pathways of serum amylase metabolism are still not fully understood. (medscape.com)
Therefore, the kidneys can be assumed to play a major role in amylase metabolism. (medscape.com)
Because high serum amylase levels are also observed in hepatic necrosis and cirrhosis, the liver is thought to play a role in amylase metabolism. (medscape.com)

In patients presenting with biliary-type abdominal pain, a 3-fold increase in serum amylase levels that returns to normal within 48-72 hours suggests stone passage through the common bile duct. (medscape.com)
Relationships among canine fasting pancreatic and biliary secretions, pancreatic duct pressure, and duodenal phase III motor activity-Boldyreff revisited. (springer.com)

Digestion begins in the mouth by salivary amylase and completed in the small intestine by pancreatic amylase. (biologyonline.com)

Amylase excretion in the urine depends upon renal function, so urinary excretion of amylase correlates with creatinine clearance. (labpedia.net)
Amylase/creatinine clearance ratio depends upon this function of the kidneys. (labpedia.net)
Amylase/creatinine clearance ratio becomes abnormal after 1 to 2 days of the serum amylase level, and it will remain abnormal as long as urine amylase is present. (labpedia.net)
Amylase/creatinine clearance ratio is more accurate than the serum amylase. (labpedia.net)
The ratio of amylase urinary clearance to creatinine clearance can be used in the diagnosis of acute and relapsing pancreatitis. (medscape.com)

The major limitation of using serum amylase measurement in diagnosing pancreatitis is the lack of specificity. (medscape.com)
A 3- to 4-times increase in serum amylase levels 4 hours after ERCP predicts the occurrence of complicating postprocedure pancreatitis. (medscape.com)
Prevalence of normal serum amylase levels in patients with acute alcoholic pancreatitis. (springer.com)
It diagnoses pancreatitis in the late stages when the blood amylase is normal. (labpedia.net)
In the case of pancreatitis, amylase level is raised in the blood for a short time, while in the urine remains for several days. (labpedia.net)
15. Jens Hegnhøj, Ove Schaffalitzky de Muckadell, Jes Lauritzen, Jens Rikardt Andersen & Erik Magid: Duodenal output and concentration of lactoferrin in chronic pancreatitis: Correlation to amylase secretion and duct morphology. (ku.dk)

A Multicellular Model of Primary Saliva Secretion in the Parotid Gland. (rochester.edu)
The parotid gland has serous cells in abundance, which produce a salivary secretion with abundant water and electrolytes responsible for the buffering capacity and protection of dental surface 1 . (bvsalud.org)
Some pathological conditions related to symptoms of xerostomia, such as radiotherapy, diabetes and SS, can alter the secretion of both parotid and submandibular glands 5-7-8 . (bvsalud.org)
Salivary amylase is synthesized by parotid, sweat, and lactating mammary glands. (medscape.com)
Other conditions in which determination of serum amylase is useful is to determine the effects of the removal of gallstones, and swelling and inflammation of the salivary/parotid glands. (medscape.com)

In addition to the autonomic innervation, neuropeptides and hormones can influence the secretion and vascularization of submandibular 6 . (bvsalud.org)

Mucus moistens the food and amylase partially digests polysaccharides (starches). (biologyonline.com)
The submandibular gland is composed of a predominance of cells characterized by mucus secretion. (bvsalud.org)

Most elevations in serum amylase are due to increased rates of amylase entry into the blood stream, decreased rates of clearance or both. (medscape.com)

Finally, the moderate overexpression of SEC16 was shown to improve the secretion of two other recombinant proteins, Trichoderma reesei endoglucanase I and Rhizopus oryzae glucan-1,4-α-glucosidase, indicating that this mechanism is of general relevance. (dtu.dk)

These concentrations reflect the origin of the lesion from extravasated pancreatic exocrine secretions resulting from pancreatic ductal disruption. (medscape.com)

Timed urine specimens can be obtained for urinary amylase and normalized to creatinine content. (medscape.com)

Acid urine decreases amylase levels. (labpedia.net)
decreases were seen in tissues and mucosal secretions, critically decreasing potential for virus transmission. (cdc.gov)

Liver (little or no amylase activity). (labpedia.net)

Plasma samples that have been anticoagulated with citrate or oxalate should be avoided because amylase is a calcium-containing enzyme and false low levels can be obtained with such specimens. (medscape.com)

Since carnitine, namely l-acetyl-carnitine (LAC), has been demonstrated to be effective in the modulation of the central hypothalamic control of GnRH secretion, we aimed to evaluate whether a combined integrative treatment for 12 weeks of LAC (250 mg/die) and l-carnitine (500 mg/die) was effective in improving the endocrine and metabolic pathways in a group of patients (n = 27) with FHA. (researchgate.net)

The pancreatic secretions incite an intense inflammatory response, which eventually leads to the development of a thick, fibrous capsule surrounding the pancreatic fluid. (medscape.com)
The reason for these differences is that acute fluid collections do not result from pancreatic ductal disruption and the subsequent leakage of pancreatic exocrine secretions. (medscape.com)

A variety of organs and body secretions contain amylase activity. (medscape.com)
Activity of α-amylase and α-glucosidase was inhibited by extracts of all S. spinosum organs. (biomedcentral.com)
Macroamylasemia is a condition of persistently elevated serum amylase activity with no apparent pancreatic disorder due to the formation of a large amylase-globulin complex, which is not excreted. (medscape.com)

This peptide is as potent as neurotensin itself in the stimulation of amylase secretion. (peptide.com)

Humans who have had a nephrectomy or have renal insufficiency have average serum amylase levels that are 50% higher than healthy individuals. (medscape.com)

The extrarenal mechanisms of amylase clearance have not been clearly defined. (medscape.com)

Anatomy13

Organisms3

Diseases1

Chemicals and Drugs55

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes9

Alpha-amylase13

Lipase11

Insulin5

Enzymes10

Pancreas10

Protein10

Exocrine secretion4

Salivary glands2

Effect on pancreatic1

Clearance of amylase2

High amylase2

Enzyme secretion2

Starch into sugars1

Inhibition2

Gastric5

Acute pancreatitis4

Carbohydrates1

Serum and urine1

Duodenum1

Fallopian1

Pancreatic disorders1

Synthesis1

Metabolism3

Biliary2

Small Intestine1

Creatinine clearance5

Pancreatitis6

Parotid5

Hormones1

Mucus2

Elevations1

Recombinant1

Concentrations1

Urinary1

Decreases2

Liver1

Citrate1

Pathways1

Fluid2

Activity3

Potent1

Renal1

Mechanisms1