• AN - not for activation of enzymes, receptors, cells, etc. by amino acids: index ENZYME ACTIVATION or specific term with /metab HN - 2005 MH - Anabaena cylindrica UI - D046868 MN - B3.280.100.150 MN - B3.440.475.100.100.150 MS - A species in the genus ANABAENA whose trichomes are composed of cylindrical cells. (nih.gov)
  • A subclass of enzymes that aminoacylate AMINO ACID-SPECIFIC TRANSFER RNA with their corresponding AMINO ACIDS. (bvsalud.org)
  • Fig. 6: Charging tRNA with unnatural amino acids using acylation chemistry. (nature.com)
  • Ribozyme (catalytic RNA) is present in ribosome and joins the amino acids together by peptide bond formation to form protein chains. (worksheetsbag.com)
  • The emergence of polypeptide catalysts for amino acid activation, the slowest step in protein synthesis, poses a significant puzzle associated with the origin of biology. (nyu.edu)
  • The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis. (systemsbiology.net)
  • Guanosine triphosphate (GTP) dependent release factors cleaves the polypeptide chain from the terminal tRNA, releasing the polypeptide from the ribosome. (worksheetsbag.com)
  • Peptide bond formation occurs between the nascent polypeptide chain and the new amino acid resulting in the elongation of polypeptide chain. (worksheetsbag.com)
  • UAA/UAG/UGA does not code for any amino acid, but brings about termination of polypeptide synthesis. (worksheetsbag.com)
  • Aminoacylation or charging of the tRNA is the process during which the amino-acyl-adenylateenzyme complex reacts with tRNA specific for the amino acid to form aminoacyl-tRNA complex. (worksheetsbag.com)
  • HN - 2005 BX - American War of Independence BX - Revolutionary War MH - Aminoacylation UI - D049148 MN - G6.535.95.55 MN - G6.535.770.50 MN - H1.181.404.95.526 MS - A reaction that introduces an aminoacyl group to a molecule. (nih.gov)
  • The aminoacyl-tRNA complex specific for the initiation codon reaches the P-site to initiate the process of protein synthesis. (worksheetsbag.com)
  • Il s'agit d'une conférence qui traite de différentes thématiques sur les ARNts : expression des ARNts, traduction du code génétique, aminoacylation des ARNts par les amino-acyl tRNA synthetases, structure et modifications des ARNts etc. (cnrs.fr)
  • These codons do not code for any amino acid. (worksheetsbag.com)
  • We deleted the anticodon binding domain from tryptophanyl-tRNA synthetase and fused the discontinuous segments comprising its active site. (nyu.edu)
  • Our preclinical data therefore provide evidence that blockade of prolyl-aminoacylation evokes a complex pro-apoptotic response beyond the canonical integrated stress response and establish a framework for its evaluation in a clinical setting. (ox.ac.uk)
  • An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe). (systemsbiology.net)
  • An aminoacyl tRNA complex reaches the A-site and attaches to mRNA codon next to initiation codon with the help of its anticodon. (worksheetsbag.com)
  • We describe here the use of protein design to show experimentally that a minimal class I aminoacyl-tRNA synthetase active site might have functioned in the distant past. (nyu.edu)
  • Class II amino acyl-tRNA. (systemsbiology.net)
  • For every single amino acid incorporated the peptide chain one ATP and two GTP molecules are used. (worksheetsbag.com)
  • Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP. (systemsbiology.net)
  • We here show that glutamyl-prolyl-tRNA synthetase (GluProRS) inhibition constitutes a novel therapeutic target. (ox.ac.uk)
  • In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA. (systemsbiology.net)
  • A peptide bond (-CO -NH-) is established between the carboxyl group (-COOH) of amino acid attached to tRNA at P-site and amino group (-NH 2 ) of amino acid attached to tRNA at A-site. (worksheetsbag.com)
  • c) Peptide bond is formed between carboxyl group of amino acid attached to tRNA at P site and amino group of amino acid attached to tRNA at A site catalysed by the enzyme peptidyl transferase. (worksheetsbag.com)