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  • resistant
  • Penicillin: Penicillinase resistant? (brainscape.com)
  • The two main internationally spread cefixime-resistant gonococcal clones, MLST ST7363 and ST1901 (NG-MAST ST1407 most frequent internationally) that also have shown their capacity to develop high-level ceftriaxone resistance (superbugs H041 and F89), likely emerged, evolved and started to disseminate in the metropolitan area, including Kanagawa, in Japan, which was followed by global transmission. (biomedcentral.com)
  • Coffey TJ, Daniels M, Enright MC et al (1999) Serotype 14 variants of the Spanish penicillin-resistant serotype 9V clone of Streptococcus pneumoniae arose by large recombinational replacements of the cpsA-pbp1a region. (springer.com)
  • These mutants: (1) are resistant to two different oxidative stressors, paraquat and the omission of 2-mercaptoethanol, (2) have reduced levels of endogenous reactive oxygen species (ROS), (3) are capable of generating live mice, and (4) transmit the stress resistance phenotype to the mice. (frontiersin.org)
  • Augmented HR appears to underpin temozolomide resistance in the recurrent lines, as these cells were cross-resistant to other agents that induced replication-associated DSBs, exhibited faster resolution of damage-induced Rad51 foci, and displayed higher levels of sister chromatid exchanges (SCE). (aacrjournals.org)
  • Imipenem
  • The beta-lactamase OXA-48 hydrolyzed imipenem at a high level and was remotely related (less than 46% amino acid identity) to the other oxacillinases. (nih.gov)
  • prevalence
  • Objective: The present ent pilot study was taken up to compare the multidrug resistance prevalence in commensal Enterococci and pathogenic Enterococci. (scribd.com)
  • Until recently bowel commensals including pilot study was taken up to compare the Enterococci were perceived as bacteria with no multidrug resistance prevalence in commensal harm. (scribd.com)
  • The 17 articles which presented concrete information about the prevalence of carbapenem resistance in East Africa were reviewed. (biomedcentral.com)
  • erythromycin
  • When introduced into strain FA19 by transformation, a single base pair deletion in the mtrR promoter sequence from strain FA6140 was sufficient to provide high-level resistance to HAs (e.g., erythromycin and Triton X-100) but only a twofold increase in resistance to penicillin. (asm.org)
  • gonococcal
  • From 1945 to 1988, penicillin was the antibiotic of choice for treatment of gonococcal infections. (asm.org)
  • These types of strains, which has been referred to as "superbugs", were isolated in Japan ("H041"), France ("F89") and Spain ("F89") from 2009 to 2011 [ 7 , 14 , 15 ], which might represent the initial phase of dissemination of gonococcal strains with high-level CRO resistance. (biomedcentral.com)
  • ABSTRACT
  • Open Access Journal │www.njcmindia.org pISSN 0976 3325│eISSN 2229 6816 Original Article ▌ STUDY OF COMMUNITY AND NOSOCOMIAL UROPATHOGENS AND THEIR DRUG RESISTANCE Smita U Shevade1, Gopal N Agrawal2 Financial Support: None declared ABSTRACT Conflict of interest: None declared Copy right: The Journal retains the copyrights of this article. (spotidoc.com)
  • antimicrobials
  • Since the introduction of antimicrobials for treatment of gonorrhoea in the mid-1930s, N. gonorrhoeae has developed resistance to all previously used first-line antimicrobials for empirical treatment of gonorrhoea. (biomedcentral.com)
  • genetic
  • The regional genetic determinants of carbapenem resistance detected were bla IMP, bla VIM-1 bla SPM-l, bla NDM-1, bla OXA-23 bla OXA-24, bla OXA-58 and bla KPC. (biomedcentral.com)
  • efflux pump
  • Resistance to these agents is most commonly due to a single base pair deletion in the regulatory region of the mtrCDE locus that results in increased expression of the energy-dependent Mtr efflux pump. (asm.org)