• Frequent inactivation of cysteine dioxygenase type 1 contributes to survival of breast cancer cells and resistance to anthracyclines. (nih.gov)
  • Comparison of the deduced amino acid sequences of BenABC with related sequences, including those for the multicomponent toluate, toluene, benzene, and naphthalene 1,2-dioxygenases, indicated that the similarly sized subunits of the hydroxylase components were derived from a common ancestor. (asm.org)
  • Amino acid residues may acquire new catalytic or redox functions from posttranslational modification. (els.net)
  • Conserved cysteine and histidine residues may bind a [2Fe-2S] Rieske-type cluster to the alpha-subunits of all the hydroxylases. (asm.org)
  • Genes encoding the electron supply system of the dioxygenase are not clustered with the dioxygenase gene but rather are located on two other distinct and separate genome segments. (asm.org)
  • Nucleotide sequences of the Acinetobacter calcoaceticus benABC genes for benzoate 1,2-dioxygenase reveal evolutionary relationships among multicomponent oxygenases. (asm.org)
  • In a postmortem exploratory study, we examined whether specific amino acid abnormalities associated with liver diseases in vivo may also be detected in human brain samples obtained at clinical autopsies. (biomedsearch.com)
  • Fine-tuning the contributions of fat, carbohydrate, and amino acid catabolism toward generation of ATP to power cells is an important aspect of physiological homeostasis. (orentreich.org)
  • The sequences of the α and β subunits of the dioxin dioxygenase exhibit only weak similarity to other three component dioxygenases, but some motifs such as the Fe(II) binding site and the [2Fe-2S] cluster ligands are conserved. (asm.org)
  • Dioxin dioxygenase activity in Escherichia coli cells containing the cloned dxnA1A2 gene was achieved only through coexpression of the cognate electron supply system from RW1. (asm.org)
  • GO annotations related to this gene include iron ion binding and cysteamine dioxygenase activity . (genecards.org)
  • In addition, we demonstrated that the dioxygenase activity of COX-2 can be analyzed independently of peroxidase activity by adding sufficient phenol, which acts as a sacrificed reductant, 22,23 at a concentration of up to 2.5 mM. (rsc.org)
  • This hypothesis includes also another class of RSS, i.e. the products of cysteine transformations: hydrogen sulfide (H 2 S) and sulfane sulfur-containing compounds. (bioscirep.org)
  • The dioxin dioxygenase was not active in E. coli cells coexpressing a class IIB electron supply system. (asm.org)
  • El-Khairy L, Vollset SE, Refsum H, Ueland PM. Plasma total cysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine Study. (ukrbiochemjournal.org)
  • Insects have a high palatability to companion and livestock animals as well as a good amino acid profile, where some species are comparable to chicken or soybean meal. (wikipedia.org)
  • This molecule, which is an amino acid, maintains cell volume by controlling osmosis - a process where water flows in and out of the sperm cells across the cell membrane, changing their shape and structure. (ivf.net)