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  • Ester
  • The aim of the present study was to evaluate the utility of the relatively hydrophilic Δ 9 -tetrahydrocannabinol (THC) prodrugs, mono and di-valine esters (THC-Val and THC-Val-Val) and the amino acid (valine)-dicarboxylic acid (hemisuccinate) ester (THC-Val-HS), with respect to ocular penetration and intraocular pressure (IOP) lowering activity. (arvojournals.org)
  • neural
  • Contained in oral contraceptives to reduce the risk of neural tube defects arising from folic acid deficiency for pregnant women who conceived during use or shortly after the discontinuation of the product. (drugbank.ca)
  • The Aspartame "dicarboxlic amino acid neural excito toxicity" is also molecularly maximized, when given the two factors entioned above, (which also maximize the methyl alcohol toxic axis toxicity. (laleva.org)
  • Medically well known examples of the extreme damage from these two factors and chemical classes, are "Guam Parkinson disease," and "Prince Edward Island shell fish: Domoic Acid" poisoning, both of which have caused extreme neurological disease epidemics in Guam (And all around the World's Oceans), and Prince Edward Island, with lifelong neural sequelae, and also additional disease generations, occurring in those epidemic's victims! (laleva.org)
  • Activity
  • Here, we validate and benchmark the CK-EDB for the homologous series of straight-chain dicarboxylic acids (oxalic-pimelic) with measurements in better agreement with Universal Quasichemical Functional Group Activity Coefficients (UNIFAC) predictions than the original data used to parametrise UNIFAC. (atmos-chem-phys.net)
  • In this research, an improved method for preparation of optically pure β-hydroxy-α-amino acids, catalyzed by serine hydroxymethyl transferase with threonine aldolase activity, is reported. (springer.com)
  • natural
  • Synthesis and x-ray analysis of cis-3,4-methylene-L-proline, the new natural amino acid from horse chestnuts, and of its trans isomer. (nih.gov)
  • active
  • There is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. (drugbank.ca)
  • human
  • For example, species of Lactobacillus live in the human vagina and derive nutrients from the environment while producing acid to prevent the overgrowth of other organisms. (answersingenesis.org)
  • product
  • In fact, the general suggestion for any such pidolic acid product is to exercise caution in their recommendation as much more research is necessary [A (drugbank.ca)