Loading...
  • fatty acid synt
  • In fatty acid synthesis, the chain elongation step consists of the condensation of acyl groups, derived from acyl‐ACP or acyl‐CoA with malonyl‐ACP. (embopress.org)
  • The present invention is directed to synthase enzymes relevant to fatty acid synthesis in plants, protein preparations, amino acid and nucleic acid sequences related thereto, and methods of use for such compositions. (google.com)
  • molecular
  • 1. A cDNA sequence encoding a Ricinus communis β-ketoacyl-ACP synthase protein, wherein said cDNA sequence comprises the mature protein encoding portion of said synthase protein, and wherein said mature protein has a molecular weight of approximately 50 kD. (google.com)
  • residues
  • Oxytocin, a hormone similar in structure to vasopressin, is analogously bound and transported by Neurophysin I. Both hormones are nine residues long, and only differ by the amino acids at positions three and eight. (wikipedia.org)
  • isolation
  • Compared to other classes of proteins, the determination of membrane protein structures has remained a challenge in large part due to the difficulty in establishing experimental conditions where the correct conformation of the protein in isolation from its native environment is preserved. (wikipedia.org)
  • permease
  • The most recent families added include the PAAP (Putative Amino Acid Permease), LIVCS (Branched Chain Amino Acid:Cation Symporter), NRAMP (Natural Resistance-Associated Macrophage Protein), CstA (Carbon starvation A protein), KUP (K⁺ Uptake Permease), BenE (Benzoate:H⁺ Virginia Symporter), and AE (Anion Exchanger). (wikipedia.org)
  • As of this edit, this article uses content from "The Amino Acid/Auxin Permease (AAAP) Family", which is licensed in a way that permits reuse under the Creative Commons Attribution-ShareAlike 3.0 Unported License, but not under the GFDL. (wikipedia.org)
  • water-soluble
  • They are transported through aqueous compartments of cells or through extracellular space by water-soluble carriers (e.g. retinol binding protein). (wikipedia.org)
  • These proteins are water-soluble but can aggregate and associate irreversibly with the lipid bilayer and become reversibly or irreversibly membrane-associated. (wikipedia.org)
  • Putative
  • Putative bifunctional protein of 748 aas and 12 TMSs with an N-terminal sodium:alanine symporter domain and a C-terminal phosphatidylserine decarboxylase proenzyme domain. (tcdb.org)
  • Oxidation
  • Ned Budisa made seminal contributions to our understanding of the role of methionine oxidation in prion protein aggregation and has discovered the roles of proline side chain conformations (endo-exo isomerism) in translation, folding and stability of proteins. (wikipedia.org)
  • Next a still unidentified protein catalyzes the selective oxidation of the benzene (as shown in Fig. 2). (wikipedia.org)
  • lipids
  • Existing at capillary levels this barrier can be understood by examining the capillary junctions and the nature of lipids and proteins within the cell membrane. (anthropogen.com)
  • antibody
  • The antibody detects a 75 kDa band on SDS-PAGE immunoblots of human PAK6 recombinant protein phosphorylated with ERK2. (abcam.com)
  • It's very hard for an antibody to navigate that glycan shield, find a protein, and neutralize. (iavireport.org)
  • Structures
  • Explore structures of Alamethicin at the protein data bank Alamethicin in Norine From "A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-A resolution. (wikipedia.org)
  • Kinetics
  • The adsorption isotherms and kinetics of two organic acids (tannic acid, humic acid) and two dyes (methylene blue, reactive dye RR222) using composite beads, activated clay, and chitosan beads were compared. (biomedsearch.com)
  • Pathways
  • Once ammonium has entered the cell via diffusion across the cytoplasmic membrane or by protein-dependent transport, it is assimilated into the major biosynthetic nitrogen donors L-glutamate and L-glutamine through one of two pathways, depending on nitrogen availability. (biomedcentral.com)
  • condensation
  • The growing chain is attached to the amino acid bearing PCP by the "condensation" (C) domain, followed by another round of the same reactions by the next module. (wikipedia.org)
  • encode
  • 74-79) Point mutations in the genes that encode arginine vasopressin and or its carrier protein neurophysin II underlie most cases of the familial, autosomal dominant disorder neurohypophyseal diabetes insipidus. (wikipedia.org)
  • kinase
  • as well as the downstream molecule extracellular indication regulated proteins kinase (ERK) 1/2, which induced the upregulation of p53 and Bcl-2-linked X proteins, mediating the next mobile apoptosis and proliferation in IECs. (biomasswars.com)
  • p16 (also known as cyclin-dependent kinase inhibitor 2A, multiple tumor suppressor 1 and as several other synonyms), is a tumor suppressor protein, that in humans is encoded by the CDKN2A gene. (wikipedia.org)
  • molecule
  • The possibility that the entire molecule is assembled as a single polyketide with a Baeyer-Villiger oxidation inserting an oxygen into the carbon backbone has been ruled out because C1 of monic acid and C9' of 9-hydroxy-nonanoic acid are both derived from C1 of acetate. (wikipedia.org)
  • synthesis
  • The absence of endoperoxide-containing products derived from 10,10-difluoroarachidonic acid has been thought to indicate the importance of a C-10 carbocation in PGG2 synthesis. (wikipedia.org)
  • This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. (wikipedia.org)
  • Mupirocin reversibly binds to the isoleucyl t-RNA synthetase in Staphylococcus aureus and Streptococcus, resulting in inhibition of protein synthesis. (wikipedia.org)
  • The inhibition of RNA synthesis was shown to be a protective mechanism in response to a lack of one amino acid, isoleucine. (wikipedia.org)
  • variants
  • this transcript contains an alternate open reading frame (ARF) that specifies a protein that is structurally unrelated to the products of the other variants. (wikipedia.org)
  • receptors
  • The cytosolic C-terminal domain contains ~50 amino acids, including a signal sequence important for localizing the receptors to clathrin-coated pits and for triggering receptor-mediated endocytosis after binding. (wikipedia.org)
  • cellular
  • Taking a systems approach, we develop and summarise the view that "serum ferritin" actually originates from damaged cells (and thus reflects cellular damage), that it contains some iron but has lost or liberated most of its normal content, and that since the protein part of ferritin is assumed to be benign, that it is this (initially) free iron that correlates with and is causative of disease. (rsc.org)
  • Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress. (wikipedia.org)
  • pathogen
  • Pneumolysin (PLY), an associate from the category of Gram-positive bacterial, cholesterol-dependent, -barrel pore-forming cytolysins, may be the main proteins virulence aspect from the dangerous respiratory pathogen, (pneumococcus). (biomasswars.com)
  • They contain DNA that codes for specific proteins (antigens) from a pathogen. (wikipedia.org)
  • specificity
  • These results indicate that SNARE proteins contribute to the overall specificity of membrane trafficking in vivo, and that the polarity of syntaxin 3 is essential for epithelial cell polarization. (rupress.org)
  • consists
  • Other underlying causes of tetrahydrobiopterin deficiency are: 6-Pyruvoyl tetrahydropterin synthase (PTPS) deficiency Autosomal recessive guanosine triphosphate cyclohydrolase I (GTPCH) deficiency Pterin-4alpha-carbinolamine dehydratase (PCD) deficiency Treatment of THB deficiencies consists of THB supplementation (2-20 mg/kg per day) or diet to control blood phenylalanine concentration and replacement therapy with neurotransmitters precursors (L-DOPA and 5-HTP) and supplements of folinic acid in DHPR deficiency. (wikipedia.org)
  • catalytic
  • Both the cyclooxygenase and the peroxidase active sites are located in the catalytic domain, which accounts for approximately 80% of the protein. (wikipedia.org)
  • indicate
  • These findings indicate that LECT is an evolutionary conserved protein, has one or more important functions, and may be involved in various diseases. (wikipedia.org)
  • interacts
  • This sequence was originally called Box A, which in now known to be the sequence that interacts with the homologue of the archaeal TATA-binding protein (TBP). (wikipedia.org)
  • several
  • Regulation of p16 is complex and involves the interaction of several transcription factors, as well as several proteins involved in epigenetic modification through methylation and repression of the promoter region. (wikipedia.org)
  • BH4 is a compound that helps convert several amino acids, including phenylalanine, to other essential molecules in the body. (wikipedia.org)
  • Mupirocin is a mixture of several pseudomonic acids, with pseudomonic acid A (PA-A) constituting greater than 90% of the mixture. (wikipedia.org)
  • structural
  • It can be activated by collectin proteins which recognize the structural pattern of polysaccharide on the surface of microorganisms. (scirp.org)
  • Other proteins have structural or mechanical functions, such as those that form the cytoskeleton, a system of scaffolding that maintains the cell shape. (wikipedia.org)
  • bile
  • UP4 Probiotics uses superstrains of live cultures like Lactobacillus acidophilus DDS-1 to support healthy digestion, withstand stomach bile and acid, and help support wellness. (pureformulas.com)
  • bind
  • The archaea protein exhibits a greater symmetry in its primary sequence and in the distribution of electrostatic charge, which is important because the higher symmetry lowers the protein's ability to bind the TATA box in a polar manner. (wikipedia.org)
  • vitro
  • Leukocyte cell-derived chemotaxin-2 (LECT2) is a protein first described in 1996 as a chemotactic factor for neutrophils, i.e. it stimulated human neutrophils to move directionally in an in vitro assay system. (wikipedia.org)
  • cell
  • Proteins are also important in cell signaling, immune responses, cell adhesion, active transport across membranes, and the cell cycle. (wikipedia.org)
  • The protein was detected in and purified from cultures of Phytohaemagglutinin-activated human T-cell leukemia SKW-3 cells. (wikipedia.org)
  • Alternatively, the DNA may be encapsulated in protein to facilitate cell entry. (wikipedia.org)
  • Alkaline phosphatase in E. coli is located in the periplasmic space and can thus be released using techniques that weaken the cell wall and release the protein. (wikipedia.org)
  • interaction
  • We investigated the interaction of PEGylated and un-PEGylated PLGA NPs with Recombinant Human Mannose-Binding Protein (HMBP) in an effort to understand the effect of surface modification on their binding to the protein. (scirp.org)
  • PRC1 and PRC2 are two protein complexes that modify the expression of p16 through the interaction of various transcription factors that execute methylation patterns that can repress transcription of p16. (wikipedia.org)
  • found
  • Serum ferritin" presents a paradox, as the iron storage protein ferritin is not synthesised in serum yet is to be found there. (rsc.org)
  • It is found in all proteins and in some artificial sweeteners. (wikipedia.org)
  • The TATA box was found in protein coding genes transcribed by RNA polymerase II. (wikipedia.org)
  • belongs
  • This protein belongs to the LDLR family and is made up of a number of functionally distinct domains, including 3 EGF-like domains, 7 LDL-R class A domains, and 6 LDL-R class B repeats. (wikipedia.org)
  • structure
  • However, their binding is shown to have different effect on the structure of the protein. (scirp.org)
  • On the other hand the fluorescence emission of the protein increased upon binding to the PLGA-PEG-NH2 indicating conformational changes in the protein structure. (scirp.org)
  • essential
  • These biochemicals can be joined together to make polymers such as DNA and proteins, essential macromolecules of life. (wikipedia.org)
  • Because the plasmid is the "vehicle" from which the immunogen is expressed, optimising vector design for maximal protein expression is essential. (wikipedia.org)
  • contain
  • These AT domains are the only domains present on MmpC, while the other three type I PKS proteins contain no AT domains. (wikipedia.org)
  • hydrogen
  • First, hydrogen is abstracted from carbon 13 of arachidonic acid, and then two molecules of oxygen are added by the PTGS2 (COX-2), giving PGG2. (wikipedia.org)
  • immune responses
  • Because these proteins are recognised as foreign, when they are processed by the host cells and displayed on their surface, the immune system is alerted, which then triggers immune responses. (wikipedia.org)
  • additional
  • Biotin protein ligases have an additional C-terminal domain which participates in biotin adenylation and dimerization. (wikipedia.org)
  • Biotin protein ligases may also have an additional N-terminal domain required for DNA binding, although this domain is not always present. (wikipedia.org)
  • Also present in mupirocin are pseudomonic acid B with an additional hydroxyl group at C8, pseudomonic acid C with a double bond between C10 and C11, instead of the epoxide of PA-A, and pseudomonic acid D with a double bond at C4` and C5` in the 9-hydroxy-nonanoic acid portion of mupirocin. (wikipedia.org)