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  • Peroxisome
  • Activation of peroxisome proliferator-activated receptor-α enhances fatty acid oxidation in human adipocytes. (biomedsearch.com)
  • There are two types of target peptides directing to peroxisome, which are called peroxisomal targeting signals (PTS). (wikipedia.org)
  • Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma. (embl.de)
  • residue
  • Optional peptide modifications are available, including residue phosphorylation and acetylation, and different formulations are possible that enable study of cellular signaling events. (thermofisher.com)
  • The NetNES 1.1 program predicted the leucine at residue 47 to be a nuclear export signal. (wikipedia.org)
  • homology
  • The human and mouse NHE6 peptides share 97% overall homology. (embl.de)
  • This 182-amino acid region that interacted with the AT2 also shares 98% homology with the corresponding region of rat NHE6 and therefore is highly conserved across species. (embl.de)
  • microarray
  • A peptide microarray (also commonly known as peptide chip or peptide epitope microarray) is a collection of peptides displayed on a solid surface, usually a glass or plastic chip. (wikipedia.org)
  • and immobilization chemistries Higher batch-to-batch reproducibility A peptide microarray is a planar slide with peptides spotted onto it or assembled directly on the surface by in-situ synthesis. (wikipedia.org)
  • Nucleus
  • The nuclear localisation signal found within the domain, GRKKR, mediates further translocation of Tat into the cell nucleus. (wikipedia.org)
  • neuronal
  • Thus, understanding all of these behavioral actions of alcohol requires some knowledge of neuronal signaling in the brain and, especially, the process of synaptic transmission. (thefreelibrary.com)
  • Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. (wikipedia.org)
  • cell
  • Live imaging is a powerful tool to understand the dynamics of cell signaling because it enables constant monitoring of an individual cell over time ( 1 ). (sciencemag.org)
  • Individual neurons usually are completely separated from one another by their outer cell membranes and thus cannot directly share electrical or chemical signals. (thefreelibrary.com)
  • We also identified the expression of the N terminal extended form of PDIP1alpha (referred to as PDIP1beta) consisting of 2649 amino acids (295 kDa) in human cultured cell lines by RT-PCR, and 5' rapid amplification of cDNA ends. (embl.de)
  • Using the proliferative response of the NAG8/7 cell line as a bioassay, we have isolated a novel cDNA from a Z210R.1 expression library by direct expression screening. (rupress.org)
  • These application-specific peptide libraries can be used in applications such as vaccine development, T- and B-cell research, antibody development, biomarker discovery, and kinase and protease studies. (thermofisher.com)
  • These application-specific peptide libraries are ready to use in applications such as vaccine development, T and B cell research, antibody development, and biomarker discovery. (thermofisher.com)
  • Sigma RBI produces specialized products for use in the field of cell signaling and neuroscience. (wikipedia.org)
  • Targeting signals are the pieces of information that enable the cellular transport machinery to correctly position a protein inside or outside the cell. (wikipedia.org)
  • This peptide chip can directly be incubated with a variety of different biological samples like purified enzymes or antibodies, patient or animal sera, cell lysates and then be detected through a label-dependent fashion, for example, by a primary antibody that targets the bound protein or modified substrates. (wikipedia.org)
  • Cellular recipients of a particular hormonal signal may be one of several cell types that reside within a number of different tissues, as is the case for insulin, which triggers a diverse range of systemic physiological effects. (wikipedia.org)
  • The typical mode of cell signaling in the endocrine system is endocrine signaling, that is, using the circulatory system to reach distant target organs. (wikipedia.org)
  • clones
  • Complementary DNA clones, encoding the LH-hCG (luteinizing hormone-human choriogonadotropic hormone) receptor were isolated by screening a lambda gt11 library with monoclonal antibodies. (sciencemag.org)
  • 1996) showed that the full-length clones contained an open reading frame of 350 amino acids with a VEGF-homologous region that is 30% identical to VEGF and 27% identical to VEGFB/VRF (601398). (lymphedemapeople.com)
  • also identified clones encoding VEGF species with 121 amino acids and 189 amino acids, which result from a 44-amino acid deletion at position 116 and a 24-amino acid insertion at position 116, respectively. (lymphedemapeople.com)
  • The insert from this clone, clone 17, was then used to screen an oligo-dT-primed Z210R.1 cDNA library made in λgt10, from which two other clones (2-1 and 1A) were isolated. (rupress.org)
  • cDNA libraries
  • In this study, human nidogen cDNAs were isolated and characterized from human placental and skin fibroblast cDNA libraries by hybridization with a mouse nidogen cDNA probe. (embl.de)
  • regulatory
  • VEGF and placental growth factor ( 601121 ) constitute a family of regulatory peptides capable of controlling blood vessel formation and permeability by interacting with 2 endothelial tyrosine kinase receptors, FLT1 ( 165070 ) and KDR/FLK1. (lymphedemapeople.com)